Nicolas Savy

Documents

Publications

	Agent based modeling in health care economics: examples in the field of thyroid cancer Romain Demeulemeester , Nicolas Savy , Pascale Grosclaude , Nadège Costa , Philippe Saint-Pierre The international journal of biostatistics, 2023, 19 (2), pp.351-368 Article dans une revue hal-04474992v1
	OTrecod: An R Package for Data Fusion using Optimal Transportation Theory Grégory Guernec , Valérie Garès , Jérémy Omer , Nicolas Savy , Philippe Saint-Pierre R Journal, 2022, 14 (4), pp.195 - 222. ⟨10.32614/RJ-2023-006⟩ Article dans une revue hal-03827398v1
	Guiding measurement protocols of connected medical devices using digital twins: A statistical methodology applied to detecting and monitoring lymphedema Loic Bethencourt , Walid Dabachine , Vincent Dejouy , Zakaria Lalmiche , Karl Neuberger IEEE Access, 2021, Online ahead of print. ⟨10.1109/ACCESS.2021.3063786⟩ Article dans une revue inserm-03167145v1
	Équiper et évaluer un « certificat de compétences cliniques » Olivier Catteau , Anne Mayère , Nicolas Savy , Odile Beyne-Rauzy STICEF (Sciences et Technologies de l'Information et de la Communication pour l'Éducation et la Formation), 2021, Numéro Spécial - Sélection de la conférence EIAH 2019, 27 (2), pp.1-28. ⟨10.23709/sticef.27.2.1⟩ Article dans une revue hal-03186732v1
	On the use of optimal transportation theory to recode variables and application to database merging Valérie Garès , Chloé Dimeglio , Grégory Guernec , Romain Fantin , Benoit Lepage The international journal of biostatistics, 2020, 16 (1), pp.article number : 20180106. ⟨10.1515/ijb-2018-0106⟩ Article dans une revue hal-01905857v2
	La fabrique des données à l’épreuve des programmes de big data Nicolas Savy , Anne Mayère , Anja Martin-Scholz , François Lambotte Actualité et dossier en santé publique, 2020, Dossier thématique Données massives et santé publique, 112, pp.27-29 Article dans une revue hal-03352270v1
	Real-world costs of illness of Hodgkin and the main B-Cell Non-Hodgkin lymphomas in France Michael Mounie , Nadège Costa , Cécile Conte , Dominique Petiot , Didier Fabre Journal of Medical Economics, 2020, 23 (3), pp.235-242. ⟨10.1080/13696998.2019.1702990⟩ Article dans une revue hal-02533775v1
	The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial Xavier Coumoul , Rémi Servien , Ludmila Juricek , Yael Kaddouch-Amar , Yannick Lippi Toxicological Sciences, 2019, 168 (2), pp.315-338. ⟨10.1093/toxsci/kfy298⟩ Article dans une revue hal-02196332v1
	Évaluation du coût de la prise en charge des patients atteints de Leucémie Myéloïde Chronique (LMC) en Midi-Pyrénées : impact économique des différents Inhibiteurs de Protéines Kinases Michael Mounié , Nadège Costa , Martin Gauthier , Aurore Palmaro , Cyrille Delpierre Journal de gestion et d’économie médicales, 2018, 36 (2), pp.109 Article dans une revue hal-01976692v1
	Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial Hélène Charbonneau , Marie Pasquié , Benoit Peyronnet , Aurélien Descazeaud , Nicolas Barry-Delongchamps Trials, 2018, 19 (1), ⟨10.1186/s13063-018-3066-9⟩ Article dans une revue hal-02180512v1
	Incremental Costs in Giant Cell Arteritis Michael Mounié , Nadège Costa , Laurent Sailler , Maryse Lapeyre-Mestre , Robert Bourrel Arthritis Care & Research = Arthritis Care and Research, 2018, 70 (7), pp.1074 - 1081. ⟨10.1002/acr.23429⟩ Article dans une revue hal-01864221v1
	On the Fleming-Harrington test for late effects in prevention randomized controlled trials Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy Journal of Statistical Theory and Practice, 2017, 11 (3), pp.418-435. ⟨10.1080/15598608.2017.1295889⟩ Article dans une revue hal-01539213v1
	Anticipative Integrals with respect to a filtered Lévy Process and Lévy-Itô decomposition Nicolas Savy , Josep Vives Communications on Stochastic Analysis, 2017, 11 (1), pp.63-85 Article dans une revue hal-01864321v1
	The Authors Respond Benoit Lepage , Sébastien Lamy , Nicolas Savy , Thierry Lang Epidemiology, 2017, 28 (3), pp.e29. ⟨10.1097/EDE.0000000000000619⟩ Article dans une revue hal-01864253v1
	Interest of the trajectory method for the evaluation of outcomes after in utero drug exposure: example of anxiolytics and hypnotics Caroline Hurault-Delarue , Cécile Chouquet , Nicolas Savy , Isabelle Lacroix , Anna-Belle Beau Pharmacoepidemiology and Drug Safety, 2017, 26 (5), pp.561-569 Article dans une revue hal-01974892v1
	How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic? Nathan Minois , Valerie Lauwers-Cances , Stephanie Savy , Michel Attal , Sandrine Andrieu Contemporary Clinical Trials Communications, 2017, 5 (23), pp.144 - 152. ⟨10.1016/j.conctc.2017.01.003⟩ Article dans une revue hal-01864356v1
	Using Poisson-gamma model to evaluate the duration of recruitment process when historical trials are available Nathan Minois , Valerie Lauwers-Cances , Stephanie Savy , Michel Attal , Sandrine Andrieu Statistics in Medicine, 2017, 36 (23), pp.3605 - 3620. ⟨10.1002/sim.7365⟩ Article dans une revue hal-01864244v1
	Un vicomte rescapé, un comte retrouvé et un chevalier ruiné. Notes sur des prisonniers de la bataille de Poitiers Françoise Lainé , Nicolas Savy Annales du Midi : revue archéologique, historique et philologique de la France méridionale, 2016, 128 (293), pp.45-67 Article dans une revue hal-01477735v1
	Additional costs of polymyalgia rheumatica with giant-cell arteritis Michael Mounié , Grégory Pugnet , Nicolas Savy , Maryse Lapeyre-Mestre , Laurent Molinier Arthritis Care & Research = Arthritis Care and Research, 2016, 11 (3), pp.418-435 Article dans une revue hal-01976676v1
	Estimation of a controlled direct effect when an effect of the exposure confounds the mediator-outcome relationship: a comparison of different methods. Benoit Lepage , Dominique Dedieu , Nicolas Savy , Thierry Lang Statistical Methods in Medical Research, 2016, 25 (2), pp.553-570 Article dans une revue hal-01864366v1
	How to take into account exposure to drugs over time in pharmacoepidemiology studies of pregnant women? Caroline Hurault-Delarue , Cécile Chouquet , Nicolas Savy , Isabelle Lacroix , Anna-Belle Beau Pharmacoepidemiology and Drug Safety, 2016, 25 (7), pp.770 - 777. ⟨10.1002/pds.4000⟩ Article dans une revue hal-01864258v1
	Estimating the Causal Effect of an Exposure on Change from Baseline Using Directed Acyclic Graphs and Path Analysis Benoit Lepage , Sébastien Lamy , Dominique Dedieu , Nicolas Savy , Thierry Lang Epidemiology, 2015, 26 (1), pp.122 - 129. ⟨10.1097/EDE.0000000000000192⟩ Article dans une revue hal-01864260v1
	An omnibus test for several hazard alternatives in prevention randomized controlled clinical trials Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy Statistics in Medicine, 2015, 34 (4), pp.541-557. ⟨10.1002/sim.6366⟩ Article dans une revue hal-01120983v1
	Big Data et Santé publique : plus que jamais, les enjeux de la connaissance Chloé Dimeglio , Cyrille Delpierre , Nicolas Savy , Thierry Lang Actualité et dossier en santé publique, 2015, 93, pp.5-7 Article dans une revue hal-01864348v1
	Mixed Hidden Markov Model for Heterogeneous Longitudinal Data with Missingness and Errors in the Outcome Variable Dominique Dedieu , Cyrille Delpierre , Sébastien Gadat , Thierry Lang , Benoit Lepage Journal de la Société Française de Statistique, 2014, 105 (1), pp.73-98 Article dans une revue hal-01864353v1
	A comparison of the constant piecewise weighted logrank and Fleming-Harrington tests Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy Electronic Journal of Statistics , 2014, 8, pp.841-860. ⟨10.2014/14-EJS911⟩ Article dans une revue hal-01056360v1
	On Ornstein-Uhlenbeck driven by Ornstein-Uhlenbeck processes Bernard Bercu , Frédéric Proïa , Nicolas Savy Statistics and Probability Letters, 2014, 85, pp.36-44. ⟨10.1016/j.spl.2013.11.002⟩ Article dans une revue hal-00915963v1
	Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model Alice Aarnink , Edward Mee , Nicolas Savy , Nicola Congy-Jolivet , Nicola Rose Immunogenetics, inPress, 66 (2), pp.105 - 113. ⟨10.1007/s00251-013-0752-3⟩ Article dans une revue hal-01864282v1
	Estimation of the instantaneous volatility Alexander Alvarez , Fabien Panloup , Monique Pontier , Nicolas Savy Statistical Inference for Stochastic Processes, 2012, 15 (1), pp.27-59. ⟨10.1007/s11203-011-9062-2⟩ Article dans une revue hal-00761710v1
	Models for patients' recruitment in clinical trials and sensitivity analysis Guillaume Mijoule , Stéphanie Savy , Nicolas Savy Statistics in Medicine, 2012, 31 (16), pp.1655-1674. ⟨10.1002/sim.4495⟩ Article dans une revue hal-00942867v1
	Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex Antoine Blancher , Alice Aarnink , Nicolas Savy , Naoyuki Takahata G3, 2012, 2, pp.123-130. ⟨10.1534/g3.111.001248⟩ Article dans une revue hal-01864345v1
	Sharp large deviations for the non-stationary Ornstein-Uhlenbeck process Bernard Bercu , Laure Coutin , Nicolas Savy Stochastic Processes and their Applications, 2012, 122, pp.3393-3424. ⟨10.1016/j.spa.2012.06.006⟩ Article dans une revue hal-00645074v1
	Sharp large deviations for the fractional Ornstein-Uhlenbeck process Bernard Bercu , Laure Coutin , Nicolas Savy SIAM Theory of Probability and its Applications, 2011, 55 (4), pp.575-610 Article dans une revue hal-00386239v1
	Upper bounds on Rubinstein distances on configuration spaces and applications Laurent Decreusefond , Aldéric Joulin , Nicolas Savy Communications on Stochastic Analysis, 2010, 4 (3), pp.377--399 Article dans une revue hal-00347899v2
	Sharp large deviations for the fractional Ornstein - Uhlenbeck process Bernard Bercu , Laure Coutin , Nicolas Savy Teoriya Veroyatnostei i ee Primeneniya, 2010, 55 (4), pp.732-771 Article dans une revue hal-01976746v1
	Anticipative calculus with respect to filtered Poisson processes L. Decreusefond , Nicolas Savy Annales de l'Institut Henri Poincaré (B) Probabilités et Statistiques, 2006, 42 (3), pp.343 - 372. ⟨10.1016/j.anihpb.2005.03.005⟩ Article dans une revue hal-01864331v1
	A general model based on two mixed Weibull distributions of bacterial resistance, for fitting various shapes of inactivation curves Louis Coroller , Ivan Leguérinel , Eric Mettler , Nicolas Savy , Pierre Mafart Applied and Environmental Microbiology, 2006, 72 (10), pp.6493-6502. ⟨10.1128/AEM.00876-06⟩ Article dans une revue hal-00552093v1
	Quantifying the combined effects of the heating time, the temperature and the recovery medium pH on the regrowth lag time of Bacillus cereus spores after a heat treatment Stéphane Gaillard , Ivan Leguérinel , Nicolas Savy , Pierre Mafart International Journal of Food Microbiology, 2005, pp.1-6 Article dans une revue hal-00653930v1
	Survival curves of heated bacterial spores: effect of environmental factors on Weibull parameters Olivier Couvert , Stéphane Gaillard , Nicolas Savy , Pierre Mafart , Ivan Leguérinel International Journal of Food Microbiology, 2005, 101 (1), pp.73-81. ⟨10.1016/j.ijfoodmicro.2004.10.048⟩ Article dans une revue hal-00560873v1
	Filtered Brownian motions as weak limit of filtered Poisson processes L. Decreusefond , Nicolas Savy Bernoulli, 2005, 11 (2), pp.283-292 Article dans une revue hal-00841352v1
	Filtered Brownian motions as weak limit of filtered Poisson processes Laurent Decreusefond , Nicolas Savy Bernoulli, 2005, 11 (2), pp.283-292 Article dans une revue hal-01864326v1

	Causality put to the test of the big data movement: a communicational approach Anja Martin-Scholz , Nicolas Savy , Anne Mayère , François Lambotte Journées du club SMAC – Statistics, Philosophy and Health, Jun 2021, Toulouse, France Communication dans un congrès hal-03352315v1
	Statistics, philosophy, and health: the SMAC 2021 webconference Nicolas Savy , Erica Em Moodie , Isabelle Drouet , Antoine Chambaz , Bruno Falissard 10èmes journées SMAC, Jun 2021, Toulouse, France. ⟨10.1515/ijb-2022-0017⟩ Communication dans un congrès hal-04027069v1
	Dispositif d'évaluation pour un certificat d'aptitudes cliniques : quelles mesures pour quelles compétences ? Olivier Catteau , Odile Beyne Rauzy , Anne Mayère , Nicolas Savy 9e Conference Environnements Informatiques pour l'Apprentissage Humain (EIAH 2019), Jun 2019, Paris, France. pp.157-168 Communication dans un congrès hal-02435357v1

	Classification of the evolutionary trajectories of cognitive functions Céline Bougel , Sébastien Déjean , Caroline Giulioli , Philippe Saint-Pierre , Nicolas Savy Journées Ouvertes Biologie, Informatique et Mathématiques (JOBIM), Jul 2019, Nantes (44000), France Poster de conférence hal-04315774v1

	Performances of Poisson–Gamma Model for Patients’ Recruitment in Clinical Trials When There Are Pauses in Recruitment or When the Number of Centres is Small Nathan Minois , Guillaume Mijoule , Stéphanie Savy , Valérie Lauwers-Cances , Sandrine Andrieu Springer Proceedings in Mathematics & Statistics book series - Statistics and Simulation - IWS 8, Vienna, Austria, September 2015, 2015 Chapitre d'ouvrage hal-01976829v1
	Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation Nicolas Savy , Stéphanie Savy , Sandrine Andrieu , Sebastien Marque Springer Proceedings in Mathematics & Statistics book series - statistics and simulation - IWS 8, Vienna, Austria, September 2015, 2015 Chapitre d'ouvrage hal-01976838v1
	Additive Cost Modelling in Clinical Trial Guillaume Mijoule , Nathan Minois , Vladimir Anisimov , Nicolas Savy Springer Proceedings in Mathematics & Statistics book series (PROMS, volume 114) -, 2014 Chapitre d'ouvrage hal-01976846v1

	Mouvement Brownien Fractionnaire, applications aux télécommunications. Calcul Stochastique relativement à des processus fractionnaires. Nicolas Savy Mathématiques [math]. Université Rennes 1, 2003. Français. ⟨NNT : ⟩ Thèse tel-00003407v1

	Investigations on Stochastic Calculus, Statistics of Processes Applied Statistics for Biology and Medical Research Nicolas Savy Applications [stat.AP]. Université de Toulouse 3 Paul Sabatier, 2014 HDR tel-01645597v1

Nicolas Savy

Publications

Agent based modeling in health care economics: examples in the field of thyroid cancer

OTrecod: An R Package for Data Fusion using Optimal Transportation Theory

Guiding measurement protocols of connected medical devices using digital twins: A statistical methodology applied to detecting and monitoring lymphedema

Équiper et évaluer un « certificat de compétences cliniques »

On the use of optimal transportation theory to recode variables and application to database merging

La fabrique des données à l’épreuve des programmes de big data

Real-world costs of illness of Hodgkin and the main B-Cell Non-Hodgkin lymphomas in France

The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial

Évaluation du coût de la prise en charge des patients atteints de Leucémie Myéloïde Chronique (LMC) en Midi-Pyrénées : impact économique des différents Inhibiteurs de Protéines Kinases

Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial

Incremental Costs in Giant Cell Arteritis

On the Fleming-Harrington test for late effects in prevention randomized controlled trials

Anticipative Integrals with respect to a filtered Lévy Process and Lévy-Itô decomposition

The Authors Respond

Interest of the trajectory method for the evaluation of outcomes after in utero drug exposure: example of anxiolytics and hypnotics

How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic?

Using Poisson-gamma model to evaluate the duration of recruitment process when historical trials are available

Un vicomte rescapé, un comte retrouvé et un chevalier ruiné. Notes sur des prisonniers de la bataille de Poitiers

Additional costs of polymyalgia rheumatica with giant-cell arteritis

Estimation of a controlled direct effect when an effect of the exposure confounds the mediator-outcome relationship: a comparison of different methods.

How to take into account exposure to drugs over time in pharmacoepidemiology studies of pregnant women?

Estimating the Causal Effect of an Exposure on Change from Baseline Using Directed Acyclic Graphs and Path Analysis

An omnibus test for several hazard alternatives in prevention randomized controlled clinical trials

Big Data et Santé publique : plus que jamais, les enjeux de la connaissance

Mixed Hidden Markov Model for Heterogeneous Longitudinal Data with Missingness and Errors in the Outcome Variable

A comparison of the constant piecewise weighted logrank and Fleming-Harrington tests

On Ornstein-Uhlenbeck driven by Ornstein-Uhlenbeck processes

Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model

Estimation of the instantaneous volatility

Models for patients' recruitment in clinical trials and sensitivity analysis

Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex

Sharp large deviations for the non-stationary Ornstein-Uhlenbeck process

Sharp large deviations for the fractional Ornstein-Uhlenbeck process

Upper bounds on Rubinstein distances on configuration spaces and applications

Sharp large deviations for the fractional Ornstein - Uhlenbeck process

Anticipative calculus with respect to filtered Poisson processes

A general model based on two mixed Weibull distributions of bacterial resistance, for fitting various shapes of inactivation curves

Quantifying the combined effects of the heating time, the temperature and the recovery medium pH on the regrowth lag time of Bacillus cereus spores after a heat treatment

Survival curves of heated bacterial spores: effect of environmental factors on Weibull parameters

Filtered Brownian motions as weak limit of filtered Poisson processes

Filtered Brownian motions as weak limit of filtered Poisson processes

Causality put to the test of the big data movement: a communicational approach

Statistics, philosophy, and health: the SMAC 2021 webconference

Dispositif d'évaluation pour un certificat d'aptitudes cliniques : quelles mesures pour quelles compétences ?

Classification of the evolutionary trajectories of cognitive functions

Performances of Poisson–Gamma Model for Patients’ Recruitment in Clinical Trials When There Are Pauses in Recruitment or When the Number of Centres is Small

Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation

Additive Cost Modelling in Clinical Trial

Mouvement Brownien Fractionnaire, applications aux télécommunications. Calcul Stochastique relativement à des processus fractionnaires.

Investigations on Stochastic Calculus, Statistics of Processes Applied Statistics for Biology and Medical Research