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CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress

 Jeremy Sitbon , Dennis Nestvogel , Caroline Kappeler , Aude Nicolas , Stephanie Maciuba , et al.
Molecular Psychiatry, 2022, 27 (2), pp.1145-1157. ⟨10.1038/s41380-021-01151-9⟩
Article dans une revue inserm-03709071v1

Successful Prediction of Substrate-binding Pocket in SLC17 Transporter Sialin

 Nicolas Pietrancosta , Christine Anne , Horst Prescher , Raquel Ruivo , Corinne Sagné , et al.
Journal of Biological Chemistry, 2012, 287 (14), pp.11489-11497. ⟨10.1074/jbc.M111.313056⟩
Article dans une revue hal-02351288v1
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CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56

 Christelle Durand , Laura Dhers , Christelle Tesson , Alessandra Tessa , Laetitia Fouillen , et al.
Human Mutation, 2018, 39 (1), pp.140 - 151. ⟨10.1002/humu.23359⟩
Article dans une revue hal-01796579v1

Identification of Privileged Scaffolds from a Diversified Chemical Library forβ-Secretase Inhibition

 Nicolas Pietrancosta , Gilles Quéléver , Cedrik Garino , Younes Laras , Stéphane Burlet , et al.
Letters in Drug Design and Discovery, 2005, 2 (8), pp.595-600. ⟨10.2174/157018005774717352⟩
Article dans une revue hal-02351752v1

New 2-bromomethyl-8-substituted-benzo[c]chromen-6-ones. Synthesis and biological properties

 Cédrik Garino , Frédéric Bihel , Nicolas Pietrancosta , Younes Laras , Gilles Quéléver , et al.
Bioorganic and Medicinal Chemistry Letters, 2005, 15 (1), pp.135-138. ⟨10.1016/j.bmcl.2004.10.018⟩
Article dans une revue istex hal-02351737v1
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Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

 Karim Dorgham , Nicolas Pietrancosta , Amel Affoune , Olivier Lucar , Tahar Bouceba , et al.
Journal of Immunology Research, 2019, 2019, pp.9804584. ⟨10.1155/2019/9804584⟩
Article dans une revue hal-02162037v1

Simple Coupling Reaction between Amino Acids and Weakly Nucleophilic Heteroaromatic Amines

 Gilles Quéléver , Stéphane Burlet , Cédrik Garino , Nicolas Pietrancosta , Younes Laras , et al.
Journal of Combinatorial Chemistry, 2004, 6 (5), pp.695-698. ⟨10.1021/cc034069p⟩
Article dans une revue hal-02351765v1
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Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B4

 Khawla Nouri , Nicolas Pietrancosta , Laurent Le Corre , Patrick Dansette , Daniel Mansuy , et al.
International Journal of Molecular Sciences, 2022, 23 (23), pp.14615. ⟨10.3390/ijms232314615⟩
Article dans une revue hal-03957648v1
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Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling

 Eric Morello , Teresa Pérez-Berezo , Chloé Boisseau , Thomas Baranek , Antoine Guillon , et al.
Frontiers in Microbiology, 2019, 10, pp.1826. ⟨10.3389/fmicb.2019.01826⟩
Article dans une revue hal-02351250v1

Enhanced delivery of γ-secretase inhibitor DAPT into the brain via an ascorbic acid mediated strategy

 Gilles Quéléver , Philippe Kachidian , Christophe Melon , Cédrik Garino , Younes Laras , et al.
Organic & Biomolecular Chemistry, 2005, 3 (13), pp.2450. ⟨10.1039/b504988a⟩
Article dans une revue istex hal-02351723v1

BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: Chromene, coumarin and quinoline

 Cédrik Garino , Nicolas Pietrancosta , Younes Laras , Vincent Moret , Amandine Rolland , et al.
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (7), pp.1995-1999. ⟨10.1016/j.bmcl.2005.12.064⟩
Article dans une revue istex hal-02351707v1
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Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin

 Lilian Dubois , Nicolas Pietrancosta , Alexandre Cabaye , Isabelle Fanget , Cécile Debacker , et al.
Journal of Medicinal Chemistry, 2020, 63 (15), pp.8231-8249. ⟨10.1021/acs.jmedchem.9b02119⟩
Article dans une revue hal-02989894v1

Design, synthesis and biological evaluation of small-azo-dyes as potent Vesicular Glutamate Transporters inhibitors

 Stephanie Daumas , Franck-Cyril Favre-Besse , Odile Poirel , Tiphaine Bersot , Elodie Kim-Grellier , et al.
European Journal of Medicinal Chemistry, 2014, 78, pp.236-247. ⟨10.1016/j.ejmech.2014.03.056⟩
Article dans une revue hal-02351262v1
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LSP5-2157 a new inhibitor of vesicular glutamate transporters

 Odile Poirel , Lauren E Mamer , Melissa A Herman , Marie Arnulf-Kempcke , Myriam Kervern , et al.
Neuropharmacology, 2019, 164, pp.107902. ⟨10.1016/j.neuropharm.2019.107902⟩
Article dans une revue hal-03043497v1

Naphthyl and Coumarinyl Biarylpiperazine Derivatives as Highly Potent Human β-Secretase Inhibitors. Design, Synthesis, and Enzymatic BACE-1 and Cell Assays

 Cédrik Garino , Taisuke Tomita , Nicolas Pietrancosta , Younes Laras , Roselyne Rosas , et al.
Journal of Medicinal Chemistry, 2006, 49 (14), pp.4275-4285. ⟨10.1021/jm0602864⟩
Article dans une revue istex hal-02351696v1
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Heterogenous distribution of VAChT and VGLUT3 in striatal cholinergic varicosities revealed by a nanoscopic analysis

 Mazarine Desplanque , Paola Cristofari , Odile Poirel , Alison Hébert , Sylvie Dumas , et al.
ENCODS 2022, Jul 2022, Paris, France. 2022
Poster de conférence hal-03972973v1

Stimuler la réponse interféron de type I avec des petites molécules : le renouveau d’une vieille idée

 Samira Khiar , Nicolas Pietrancosta , Pierre-Olivier Vidalain
Biologie Aujourd'hui, 2015, 209 (2), pp.145-159. ⟨10.1051/jbio/2015015⟩
Article dans une revue istex hal-02351277v1

Rose Bengal analogs and vesicular glutamate transporters (VGLUTs)

 Nicolas Pietrancosta
Bioorganic and Medicinal Chemistry, 2010, ⟨10.1016/j.bmc.2010.06.069⟩
Article dans une revue hal-02351315v1
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GRID1/ GluD1 homozygous variants linked to intellectual disability and spastic paraplegia impair mGlu1/5 receptor signaling and excitatory synapses

 Dévina Ung , Ludovic Tricoire , Nicolas Pietrancosta , Andjela Zlatanovic , Ben Pode-Shakked , et al.
Molecular Psychiatry, 2024, ⟨10.1038/s41380-024-02469-w⟩
Article dans une revue hal-03871407v2
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Heterogenous distribution of VAChT and VGLUT3 in striatal cholinergic varicosities revealed by a nanoscopic analysis

 Mazarine Desplanque , Paola Cristofari , Odile Poirel , Alison Hébert , Sylvie Dumas , et al.
FENS Forum 2022, Jul 2022, Paris, France. 2022
Poster de conférence hal-03972255v1

Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.

 Lionel Ducassou , Gabriella Jonasson , Laura Dhers , Nicolas Pietrancosta , Booma Ramassamy , et al.
BBA - Biochimica et Biophysica Acta, 2015, 1850 (7), pp.1426-37. ⟨10.1016/j.bbagen.2015.03.014⟩
Article dans une revue hal-01449701v1

Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B 12 -trafficking proteins ABCD4 and LMBD1

 Victoria Fettelschoss , Patricie Burda , Corinne Sagné , David Coelho , Corinne de Laet , et al.
Journal of Biological Chemistry, 2017, 292 (28), pp.11980-11991. ⟨10.1074/jbc.M117.784819⟩
Article dans une revue hal-02351269v1
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Pseudoxanthoma Elasticum overlaps Hereditary Spastic Paraplegia Type 56

 Anne Legrand , Claire Pujol , Christelle M Durand , Aurélie Mesnil , Isabelle Rubera , et al.
Journal of Internal Medicine, 2021, 289 (5), pp.709. ⟨10.1111/joim.13193⟩
Article dans une revue pasteur-03099934v1

Novel cyclized Pifithrin-α p53 inactivators: synthesis and biological studies

 Nicolas Pietrancosta , Flavio Maina , Rosanna Dono , Anice Moumen , Cédrik Garino , et al.
Bioorganic and Medicinal Chemistry Letters, 2005, 15 (6), pp.1561-1564. ⟨10.1016/j.bmcl.2005.01.075⟩
Article dans une revue istex hal-02351727v1

Design of β-Secretase Inhibitors by Introduction of a Mandelyl Moiety in DAPT Analogues

 Nicolas Pietrancosta , Gilles Quéléver , Younes Laras , Cédrik Garino , Stéphane Burlet , et al.
Australian Journal of Chemistry, 2005, 58 (8), pp.585. ⟨10.1071/ch05102⟩
Article dans une revue hal-02351745v1

Synthesis of Quinoline Dicarboxylic Esters as Biocompatible Fluorescent Tags

 Franck-Cyril Favre-Besse , Odile Poirel , Tiphaine Bersot , Elodie Kim-Grellier , Stéphanie Daumas , et al.
Journal of Organic Chemistry, 2012, 77 (18), pp.8294-8302. ⟨10.1021/jo301652j⟩
Article dans une revue hal-02351282v1

Thiazolamide - Ascorbic Acid Conjugate: a γ-Secretase Inhibitor with Enhanced Blood - Brain Barrier Permeation

 Younes Laras , Mahmoud Sheha , Nicolas Pietrancosta , Jean-Louis Kraus
Australian Journal of Chemistry, 2007, 60 (2), pp.128. ⟨10.1071/ch06441⟩
Article dans une revue hal-02351686v1

Regulation of IRE1 RNase activity by the Ribonuclease inhibitor 1 (RNH1)

 Quentin Tavernier , Evangeline Bennana , Virginie Poindessous , Céline Schaeffer , Luca Rampoldi , et al.
Cell Cycle, 2018, 17 (15), pp.1901-1916. ⟨10.1080/15384101.2018.1506655⟩
Article dans une revue hal-02351253v1

SELECTIVE ORGANIC CATION TRANSPORTERS INHIBITORS FOR THE TREATMENT OF DEPRESSIVE DISORDERS

 Sophie Gautron , Nicolas Pietrancosta , Francine Acher , Laetitia Chausset-Boissarie
France, Patent n° : WO2019012150. 2019
Brevet inserm-04028993v1
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Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay

 Simon Hayek , Nassima Bekaddour , Laurie Besson , Rodolphe Alves de Sousa , Nicolas Pietrancosta , et al.
Slas Discovery, 2018, 24 (1), pp.25-37. ⟨10.1177/2472555218797078⟩
Article dans une revue hal-02324386v1
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