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Starch based microparticles radiolabelling with 99mTc and 188Re for diagnostic and therapy of Hepatocellular carcinoma

Elise Verger , Annabelle Cikankowitz , Antoine Bouvier , Nicolas Lepareur , Jean-Pierre Benoit , et al.
8th International Symposium on Technetium and Rhenium: Science and Utilization, 2014, Pornichet, France
Communication dans un congrès hal-03180807v1

Evaluation des réponses immunitaires dans le cadre de la radiothérapie interne nanovectorisée du Glioblastome

Claire Vanpouille-Box , Emmanuel Garcion , Franck Lacœuille , Laurent Lemaire , Nicolas Lepareur , et al.
5ème journées de l'IFR 132, 2010, Angers, France. 2010
Poster de conférence hal-03180647v1
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VECTORISATIONS ACTIVE ET PASSIVE DE RADIOPHARMACEUTIQUES DU TECHNETIUM-99m ET DU RHENIUM-188 POUR L'IMAGERIE MEDICALE ET LA THERAPIE

Nicolas Lepareur
Autre. Université Rennes 1; Università degli studi di Ferrara, 2003. Français. ⟨NNT : ⟩
Thèse tel-00128645v1

Occupational radiation exposure of medical staff performing (90)Y-loaded microsphere radioembolization

Sophie Laffont , Yan Rolland , Valérie Ardisson , Julien Edeline , Marc Pracht , et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 (5), pp.824-831. ⟨10.1007/s00259-015-3277-1⟩
Article dans une revue hal-01255872v1

In Vitro Demonstration of Synergy/Additivity Between 188Rhenium and Sorafenib on Hepatoma Lines: Preliminary Results

Marc Pracht , Julien Edeline , Nicolas Lepareur , Laurence Lenoir , Valérie Ardisson , et al.
Anticancer Research, 2013, 33 (9), pp.3871-3877
Article dans une revue hal-00934873v1

Characterization of the distribution, retention, and efficacy of internal radiation of (188)Re-lipid nanocapsules in an immunocompromised human glioblastoma model

Annabelle Cikankowitz , Anne Clavreul , Clément Tétaud , Laurent Lemaire , Audrey Rousseau , et al.
Journal of Neuro-Oncology, 2017, 131 (1), pp.49-58. ⟨10.1007/s11060-016-2289-4⟩
Article dans une revue hal-01451658v1

Elaboration of nanocarriers based on biocompatible polymers for the specific vectorisation of an imaging agent

Oceane Malval , Elise Vene , Pascal Loyer , Sandrine Cammas-Marion , Nicolas Lepareur
Journal of Labelled Compounds and Radiopharmaceuticals, 2019, 62, pp.S356-S357
Article dans une revue hal-02177795v1

Therapeutic composition including an organic lipid phase and a complex of a rare earth radioisotope

Nicolas Lepareur , Etienne Garin , Nicolas Noiret , Valérie Ardisson
Patent n° : FR 2993462. 2014, pp.20
Brevet hal-00936718v1

Impact of tamoxifen and dexamethasone on membrane fluidity and tumor targeting of lipiodol in hepatocellular carcinoma

Stéphanie Becker , Nicolas Lepareur , Valérie Ardisson , Odile Sergent , Sahar Bayat , et al.
Journal of Nuclear Medicine, 2010, 51 (Supplement 2), pp.1130
Article dans une revue hal-01117641v1

Evaluation OF Immune Responses after Nanovectorized Internal Radiotherapy for Glioblastomas

Claire Vanpouille-Box , Emmanuel Garcion , Franck Lacœuille , Laurent Lemaire , Nicolas Lepareur , et al.
World Molecular Imaging Congress (WMIC), 2010, Kyoto, Japan
Communication dans un congrès hal-03180827v1
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Cold Kit Labeling: The Future of (68)Ga Radiopharmaceuticals?

Nicolas Lepareur
Frontiers in Medicine, 2022, 9, pp.812050. ⟨10.3389/fmed.2022.812050⟩
Article dans une revue hal-03594485v1
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Gemcitabine and Oxaliplatin, but Not Sorafenib or Paclitaxel, Have a Synergistic Effect with Yttrium-90 in Reducing Hepatocellular Carcinoma and Cholangiocarcinoma Cell Line Viability.

Julien Edeline , Cédric Coulouarn , Laurence Crouzet , Marc Pracht , Nicolas Lepareur , et al.
JVIR: Journal of Vascular and Interventional Radiology, 2015, 26 (12), pp.1874--1878.e2. ⟨10.1016/j.jvir.2015.06.032⟩
Article dans une revue hal-01237102v1

Spectroscopic Investigations of Fine-Tuned Energy Differences in a Series of Substituted Rhenium and Technetium Complexes [M(RPhCS3)2(RPhCS2)]

Nicolas Lepareur , Nicolas Noiret , J. Jeftic
Spectroscopy Letters : An International Journal for Rapid Communication, 2006, 39, pp.45-61
Article dans une revue hal-00403570v1

Composition for therapeutic use, including an organic lipid phase and a rare- earth radioisotope complex

Nicolas Lepareur , Etienne Garin , Nicolas Noiret , Valérie Ardisson
Patent n° : WO 2014012997. 2014, pp.25
Brevet hal-00936709v1

Développement d'un marquage du lipiodol au 99mTc et étude de biodistribution sur le porc sain

E. Garin , N. Noiret , Charles-Henri Malbert , A. Roucoux , Nicolas Lepareur , et al.
41. Colloque, 2003, Tours, France
Communication dans un congrès hal-02829415v1

Développement d'un nouvel outil de radiothérapie interne dans le glioblastome

D Séhédic , Igor Chourpa , E Renou , Laurent Lemaire , Nicolas Lepareur , et al.
Le microbiote dans tous ses états. Journée de la SFR-ICAT 4208, 2015, Angers, France
Communication dans un congrès hal-02615953v1

68Ga and 188Re starch-based microparticles as theranostic tool for the hepatocellular carcinoma: Radiolabeling and preliminary in vivo rat studies

E. Verger , P. Drion , G. Meffre , C. Bernard , L. Duwez , et al.
PLoS ONE, 2016, 11 (10), pp.e0164626. ⟨10.1371/journal.pone.0164626⟩
Article dans une revue hal-01398433v1

Stable and Inert Yttrium(III) Complexes with Pyclen-Based Ligands Bearing Pendant Picolinate Arms: Toward New Pharmaceuticals for β-Radiotherapy

Mariane Le Fur , Maryline Beyler , Enikő Molnár , Olivier Fougere , David Esteban-Gómez , et al.
Inorganic Chemistry, 2018, 57 (4), pp.2051-2063. ⟨10.1021/acs.inorgchem.7b02953⟩
Article dans une revue hal-01701694v1
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The role of the capping bond effect on pyclen Y-nat(3+)/Y-90(3+) chelates: full control of the regiospecific N-functionalization makes the difference

Mariane Le Fur , Maryline Beyler , Eniko Molnar , Olivier Fougere , David Esteban-Gomez , et al.
Chemical Communications, 2017, 53 (69), pp.9534-9537. ⟨10.1039/c7cc05088g⟩
Article dans une revue hal-01616222v1

Design, Synthesis, and Reactivity of Multidentate Ligands with Rhenium(I) and Rhenium(V) Cores

Jinhui Wang , Romain Eychenne , M. Wolff , Sonia Mallet-Ladeira , Nicolas Lepareur , et al.
European Journal of Inorganic Chemistry, 2017, 2017 (33), pp.3908-3918. ⟨10.1002/ejic.201700632⟩
Article dans une revue hal-01619479v1

Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity.

Stéphanie Becker , Nicolas Lepareur , Virginie Cadeillan , Valérie Ardisson , Sahar Bayat , et al.
Cancer Biotherapy and Radiopharmaceuticals, 2012, 27 (2), pp.149-55. ⟨10.1089/cbr.2011.1072⟩
Article dans une revue hal-00867018v1

New tricarbonylrhenium(I) complexes : from structural study to a potential therapeutic radiopharmaceutical to target hepatocellular carcinoma metastases

Jinhui Wang , Romain Eychenne , P. Loyer , Nicolas Lepareur , Eric Benoist
TERACHEM 2018, Sep 2018, Bressanone, Italy
Poster de conférence hal-02339448v1

Translational view of an innovative nanotool for glioblastoma therapeutic strategy : 188Re-SSS lipid nanocapsules

Annabelle Cikankowitz , Camille Belloche , G. Chassain , Franck Lacœuille , Elise Verger , et al.
3rd Nano today Conference, 2013, Singapour, Singapore. 2013
Poster de conférence hal-03184073v1

Rhenium-188: application for glioblastoma internal radiotherapy

Annabelle Cikankowitz , Clément Tétaud , Camille Belloche , Elise Verger , Olivier-François Couturier , et al.
8th International Symposium on Technetium and Rhenium: Science and Utilization, 2014, Pornichet, France
Communication dans un congrès hal-03180808v1

Tuning the lipophilic nature of pyclen-based 90Y3+ radiopharmaceuticals for β-radiotherapy

Mariane Le Fur , Olivier Fougère , Nicolas Lepareur , Olivier Rousseaux , Raphaël Tripier , et al.
Metallomics, 2021, 13 (12), ⟨10.1093/mtomcs/mfab070⟩
Article dans une revue hal-03468303v1
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Cell Uptake and Biocompatibility of Nanoparticles Prepared from Poly(benzyl malate) (Co)polymers Obtained through Chemical and Enzymatic Polymerization in Human HepaRG Cells and Primary Macrophages

H. Casajus , S. Saba , M. Vlach , E. Vène , C. Ribault , et al.
Polymers, 2018, 10 (11), pp.1244. ⟨10.3390/polym10111244⟩
Article dans une revue hal-01939026v1

Lipid nanocapsules loaded with rhenium-188 reduce tumor progression in a rat hepatocellular carcinoma model.

Claire Vanpouille-Box , Franck Lacoeuille , Jérôme Roux , Christophe Aubé , Emmanuel Garcion , et al.
PLoS ONE, 2011, 6 (3), pp.e16926. ⟨10.1371/journal.pone.0016926⟩
Article dans une revue hal-00741696v1
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Locoregional Confinement and Major Clinical Benefit of 188 Re-Loaded CXCR4-Targeted Nanocarriers in an Orthotopic Human to Mouse Model of Glioblastoma

Delphine Séhédic , Igor Chourpa , Clément Tétaud , Audrey Griveau , Claire Loussouarn , et al.
Theranostics, 2017, 7 (18), pp.4517 - 4536. ⟨10.7150/thno.19403⟩
Article dans une revue inserm-01631431v1
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(188)Re-SSS/Lipiodol: Development of a Potential Treatment for HCC from Bench to Bedside.

Nicolas Lepareur , Valérie Ardisson , Nicolas Noiret , Etienne Garin
International Journal of Molecular Imaging, 2012, 2012, 278306 (9 p.). ⟨10.1155/2012/278306⟩
Article dans une revue hal-00866975v1

Therapy of hepatocellular carcinoma with Rhenium-188 Lipiodol

Nicolas Lepareur , Valérie Ardisson , Etienne Garin , Nicolas Noiret
current radiopharma, 2008, 1, pp.87-92
Article dans une revue hal-00403344v1