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		Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy Nicolas Joubert , Caroline Denevault-Sabourin , Francesca Bryden , Marie-Claude Viaud-Massuard European Journal of Medicinal Chemistry, 2017, 142, pp.393-415. ⟨10.1016/j.ejmech.2017.08.049⟩ Article dans une revue hal-02389855v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate Imene Ait Mohamed Amar , Steve Huvelle , Emmanuel Douez , Stéphanie Letast , Sylvain Henrion , et al. European Journal of Medicinal Chemistry, 2022, 229, 11 p. ⟨10.1016/j.ejmech.2021.114063⟩ Article dans une revue hal-03662472v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Antibody–Drug Conjugates: The Last Decade Nicolas Joubert , Alain Beck , Charles Dumontet , Caroline Denevault-Sabourin Pharmaceuticals, 2020, 13 (9), pp.245. ⟨10.3390/ph13090245⟩ Article dans une revue hal-03810033v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Successful Drug Discovery Caroline Denevault-Sabourin , Francesca Bryden , Marie-Claude Viaud-Massuard , Nicolas Joubert Wiley, 1, 2019, ⟨10.1002/9783527814695.ch3⟩ Ouvrages hal-02389951v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells Valentina Corvaglia , Imène Ait Mohamed Amar , Véronique Garambois , Stéphanie Letast , Aurélie Garcin , et al. Pharmaceuticals, 2021, 14 (7), pp.624. ⟨10.3390/ph14070624⟩ Article dans une revue hal-03456576v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthèse et évaluation de nouveaux nucléosides ciblant l'hépatite C dans un système réplicon Nicolas Joubert Autre. Université d'Orléans, 2006. Français. ⟨NNT : ⟩ Thèse tel-00250329v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Site-specific conjugation of auristatins onto engineered antibody fragments to target her2-positive breast cancer in vitro Imène Ait Mohamed Amar , Nicolas Aubrey , Emilie Allard-Vannier , Juliette Lamamy , Clément Gautron , et al. 32ème Colloque Biotechnocentre, Oct 2019, Seillac, France. , 85 p., 2019 Poster de conférence hal-02478465v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Optimizing Antibody-Drug Conjugates for Targeted Delivery of Therapeutics, chapter Antibody–drug conjugates: historical developments and mechanisms of action Norbert Sewald , Nicolas Joubert Future Science Ltd; Future Science Ltd, 2015, ⟨10.4155/fseb2013.14.27⟩ Ouvrages hal-02390446v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide Katel Hervé-Aubert , Emilie Allard-Vannier , Nicolas Joubert , Zineb Lakhrif , Christophe Alric , et al. Bioconjugate Chemistry, 2018, 29 (5), pp.1553-1559. ⟨10.1021/acs.bioconjchem.8b00091⟩ Article dans une revue hal-01757120v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation Camille Martin , Guillaume Brachet , Cyril Colas , Emilie Allard-Vannier , Claire Kizlik-Masson , et al. Pharmaceuticals, 2019, 12 (4), pp.176. ⟨10.3390/ph12040176⟩ Article dans une revue hal-02425275v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Therapeutic antibodies – natural and pathological barriers and strategies to overcome them Yara Al Ojaimi , Timothée Blin , Juliette Lamamy , Matthieu Gracia , Aubin Pitiot , et al. Pharmacology and Therapeutics, 2021, pp.108022. ⟨10.1016/j.pharmthera.2021.108022⟩ Article dans une revue hal-03531953v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody–drug conjugates Francesca Bryden , Camille Martin , Stéphanie Letast , Eva Lles , Inmaculada Viéitez-Villemin , et al. Organic & Biomolecular Chemistry, 2018, 16 (11), pp.1882 - 1889. ⟨10.1039/c7ob02780j⟩ Article dans une revue hal-01808620v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro Nicolas Aubrey , Émilie Allard-Vannier , Camille Martin , Francesca Bryden , Stéphanie Letast , et al. Bioconjugate Chemistry, 2018, 29 (11), pp.3516-3521. ⟨10.1021/acs.bioconjchem.8b00668⟩ Article dans une revue hal-01907352v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27–28, 2017, Tours, France Camille Martin , Claire Kizlik-Masson , André Pèlegrin , Hervé Watier , Marie-Claude Viaud-Massuard , et al. mAbs, 2018, 10 (2), pp.210-221. ⟨10.1080/19420862.2017.1412130⟩ Article dans une revue hal-02290096v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Protein Chemical Modification on Endogenous Amino Acids Emmanuel Baslé , Nicolas Joubert , Mathieu Pucheault Chemistry & biology, 2010, 17 (3), pp.213 - 227. ⟨10.1016/j.chembiol.2010.02.008⟩ Article dans une revue hal-00869381v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity Vanessa Escuret , Vincent Aucagne , Nicolas Joubert , David Durantel , Kimberly Rapp , et al. Bioorganic and Medicinal Chemistry, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩ Article dans une revue istex hal-02086013v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Increment in Drug Loading on an Antibody–Drug Conjugate Increases Its Binding to the Human Neonatal Fc Receptor in Vitro Guillaume Brachet , Renaud Respaud , Christophe Arnoult , Corinne Henriquet , Christine Dhommée , et al. Molecular Pharmaceutics, 2016, 13 (4), pp.1405-1412. ⟨10.1021/acs.molpharmaceut.6b00082⟩ Article dans une revue hal-02294537v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer Emmanuel Douez , Emilie Allard-Vannier , Imène Ait Mohamed Amar , Louis Jolivet , Fanny Boursin , et al. Journal of Controlled Release, 2024, 366, pp.567-584. ⟨10.1016/j.jconrel.2024.01.012⟩ Article dans une revue hal-04394580v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment–Drug Conjugates (FDCs) Louis Jolivet , Imène Ait Mohamed Amar , Catherine Horiot , Fanny Boursin , Cyril Colas , et al. Pharmaceutics, 2022, 14 (8), 16 p. ⟨10.3390/pharmaceutics14081524⟩ Article dans une revue hal-03770274v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis Julie Broggi , Nicolas Joubert , Vincent Aucagne , Sabine Berteina-Raboin , S. Diez-Gonzalez , et al. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩ Article dans une revue hal-02086003v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Pharmacological characterization of low molecular weight biased agonists at the follicle stimulating hormone receptor Francesco de Pascali , Mohammed Akli Ayoub , Riccardo Benevelli , Silvia Sposini , Jordan Lehoux , et al. International Journal of Molecular Sciences, 2021, 22 (18), pp.1-23. ⟨10.3390/ijms22189850⟩ Article dans une revue hal-03351267v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More

Filtrer vos résultats

Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy

Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate

Antibody–Drug Conjugates: The Last Decade

Successful Drug Discovery

Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells

Synthèse et évaluation de nouveaux nucléosides ciblant l'hépatite C dans un système réplicon

Site-specific conjugation of auristatins onto engineered antibody fragments to target her2-positive breast cancer in vitro

Optimizing Antibody-Drug Conjugates for Targeted Delivery of Therapeutics, chapter Antibody–drug conjugates: historical developments and mechanisms of action

Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide

In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation

Therapeutic antibodies – natural and pathological barriers and strategies to overcome them

Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody–drug conjugates

Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro

Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27–28, 2017, Tours, France

Protein Chemical Modification on Endogenous Amino Acids

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity

Increment in Drug Loading on an Antibody–Drug Conjugate Increases Its Binding to the Human Neonatal Fc Receptor in Vitro

Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer

Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment–Drug Conjugates (FDCs)

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

Pharmacological characterization of low molecular weight biased agonists at the follicle stimulating hormone receptor