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Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy
Nicolas Joubert
,
Caroline Denevault-Sabourin
,
Francesca Bryden
,
Marie-Claude Viaud-Massuard
Article dans une revue
hal-02389855v1
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Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate
Imene Ait Mohamed Amar
,
Steve Huvelle
,
Emmanuel Douez
,
Stéphanie Letast
,
Sylvain Henrion
,
et al.
Article dans une revue
hal-03662472v1
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Antibody–Drug Conjugates: The Last Decade
Nicolas Joubert
,
Alain Beck
,
Charles Dumontet
,
Caroline Denevault-Sabourin
Article dans une revue
hal-03810033v1
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Successful Drug Discovery
Caroline Denevault-Sabourin
,
Francesca Bryden
,
Marie-Claude Viaud-Massuard
,
Nicolas Joubert
Ouvrages
hal-02389951v1
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Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells
Valentina Corvaglia
,
Imène Ait Mohamed Amar
,
Véronique Garambois
,
Stéphanie Letast
,
Aurélie Garcin
,
et al.
Article dans une revue
hal-03456576v1
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Site-specific conjugation of auristatins onto engineered antibody fragments to target her2-positive breast cancer in vitro
Imène Ait Mohamed Amar
,
Nicolas Aubrey
,
Emilie Allard-Vannier
,
Juliette Lamamy
,
Clément Gautron
,
et al.
32ème Colloque Biotechnocentre, Oct 2019, Seillac, France. , 85 p., 2019
Poster de conférence
hal-02478465v1
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Synthèse et évaluation de nouveaux nucléosides ciblant l'hépatite C dans un système réplicon
Nicolas Joubert
Autre. Université d'Orléans, 2006. Français. ⟨NNT : ⟩
Thèse
tel-00250329v1
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Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro
Nicolas Aubrey
,
Émilie Allard-Vannier
,
Camille Martin
,
Francesca Bryden
,
Stéphanie Letast
,
et al.
Article dans une revue
hal-01907352v1
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Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody–drug conjugates
Francesca Bryden
,
Camille Martin
,
Stéphanie Letast
,
Eva Lles
,
Inmaculada Viéitez-Villemin
,
et al.
Article dans une revue
hal-01808620v1
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Therapeutic antibodies – natural and pathological barriers and strategies to overcome them
Yara Al Ojaimi
,
Timothée Blin
,
Juliette Lamamy
,
Matthieu Gracia
,
Aubin Pitiot
,
et al.
Article dans une revue
hal-03531953v1
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Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27–28, 2017, Tours, France
Camille Martin
,
Claire Kizlik-Masson
,
André Pèlegrin
,
Hervé Watier
,
Marie-Claude Viaud-Massuard
,
et al.
Article dans une revue
hal-02290096v1
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Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity
Vanessa Escuret
,
Vincent Aucagne
,
Nicolas Joubert
,
David Durantel
,
Kimberly Rapp
,
et al.
Article dans une revue
istex
hal-02086013v1
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Protein Chemical Modification on Endogenous Amino Acids
Emmanuel Baslé
,
Nicolas Joubert
,
Mathieu Pucheault
Article dans une revue
hal-00869381v1
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Optimizing Antibody-Drug Conjugates for Targeted Delivery of Therapeutics, chapter Antibody–drug conjugates: historical developments and mechanisms of action
Norbert Sewald
,
Nicolas Joubert
Ouvrages
hal-02390446v1
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In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation
Camille Martin
,
Guillaume Brachet
,
Cyril Colas
,
Emilie Allard-Vannier
,
Claire Kizlik-Masson
,
et al.
Article dans une revue
hal-02425275v1
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Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide
Katel Hervé-Aubert
,
Emilie Allard-Vannier
,
Nicolas Joubert
,
Zineb Lakhrif
,
Christophe Alric
,
et al.
Article dans une revue
hal-01757120v1
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Increment in Drug Loading on an Antibody–Drug Conjugate Increases Its Binding to the Human Neonatal Fc Receptor in Vitro
Guillaume Brachet
,
Renaud Respaud
,
Christophe Arnoult
,
Corinne Henriquet
,
Christine Dhommée
,
et al.
Article dans une revue
hal-02294537v1
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Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis
Julie Broggi
,
Nicolas Joubert
,
Vincent Aucagne
,
Sabine Berteina-Raboin
,
S. Diez-Gonzalez
,
et al.
Article dans une revue
hal-02086003v1
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Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment–Drug Conjugates (FDCs)
Louis Jolivet
,
Imène Ait Mohamed Amar
,
Catherine Horiot
,
Fanny Boursin
,
Cyril Colas
,
et al.
Article dans une revue
hal-03770274v1
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Pharmacological characterization of low molecular weight biased agonists at the follicle stimulating hormone receptor
Francesco de Pascali
,
Mohammed Akli Ayoub
,
Riccardo Benevelli
,
Silvia Sposini
,
Jordan Lehoux
,
et al.
Article dans une revue
hal-03351267v1
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Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer
Emmanuel Douez
,
Emilie Allard-Vannier
,
Imène Ait Mohamed Amar
,
Louis Jolivet
,
Fanny Boursin
,
et al.
Article dans une revue
hal-04394580v1
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