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Nicolas JAULIN

15
Documents
Identifiants chercheurs

Présentation

Team [Immunologie du transfert de gène](https://umr1089.univ-nantes.fr/axes-de-recherche/immunologie-du-transfert-de-genes-a-l-aide-de-vecteurs-aav/immunologie-du-transfert-de-genes-a-l-aide-de-vecteurs-aav-2194746.kjsp?RH=1518531770791 "Immunologie du transfert de gène") &amp; [Gene therapy immunology Core](https://umr1089.univ-nantes.fr/plateaux-technologiques/gti/immuno-monitorage-des-etudes-de-therapie-genique-gti-core--2194754.kjsp?RH=1518531897125 "Gene therapy immunology Core") Inserm UMR 1089 - Translationnal Gene Therapy for Genetic Diseases <nicolas.jaulin@univ-nantes.fr> +33 28 08 04 53

Publications

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Transcriptomic Analysis Reveals the Inability of Recombinant AAV8 to Activate Human Monocyte-Derived Dendritic Cells

Samer Masri , Laure Carré , Nicolas Jaulin , Céline Vandamme , Célia Couzinié
International Journal of Molecular Sciences, 2023, 24 (13), pp.10447. ⟨10.3390/ijms241310447⟩
Article dans une revue hal-04193929v1
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AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation

Gwladys Gernoux , Mickaël Guilbaud , Marie Devaux , Malo Journou , Virginie Pichard
Molecular Therapy - Methods and Clinical Development, 2021, 20, pp.660 - 674. ⟨10.1016/j.omtm.2021.02.003⟩
Article dans une revue inserm-03172941v1
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Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation

Celine Vandamme , Rebecca Xicluna , Leslie Hesnard , Marie Devaux , Nicolas Jaulin
Frontiers in Immunology, 2020, 10, pp.3110. ⟨10.3389/fimmu.2019.03110⟩
Article dans une revue inserm-02447186v1
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Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries

Pauline F Schmit , Simon Pacouret , Eric Zinn , Elizabeth Telford , Fotini Nicolaou
Molecular Therapy - Methods and Clinical Development, 2019, 17, pp.107-121. ⟨10.1016/j.omtm.2019.11.014⟩
Article dans une revue inserm-02448091v1

5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity

Mickaël Guilbaud , Marie Devaux , Célia Couzinié , Johanne Le Duff , Alice Toromanoff
Human Gene Therapy, 2019
Article dans une revue inserm-02052292v1
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Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits

Judith Lorant , Thibaut Larcher , Nicolas Jaulin , Benoit Hedan , Aurélie Lardenois
Cell Transplantation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩
Article dans une revue hal-01812518v1
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Early Interaction of Adeno-Associated Virus Serotype 8 Vector with the Host Immune System Following Intramuscular Delivery Results in Weak but Detectable Lymphocyte and Dendritic Cell Transduction

Gwladys Gernoux , Mickaël Guilbaud , Laurence Dubreil , Thibaut Larcher , Candice Babarit
Human Gene Therapy, 2015, 26 (1), pp.1 - 13. ⟨10.1089/hum.2014.070⟩
Article dans une revue inserm-01734763v1
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Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer.

A Moreau , C Vandamme , Mercedes Segovia , M. Devaux , Mickaël Guilbaud
Mol Ther Methods Clin Dev, 2014, 1
Article dans une revue hal-01222897v1

Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune responses

Gwladys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud
16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States
Communication dans un congrès hal-02749165v1

Macaque immune responses following AAV-based gene transfer to the skeletal muscle: addressing the method of vector delivery

Gwladys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud
European Society of Gene and Cell Therapy/French Society of Cell and Gene Therapy Collaborative Congress, Oct 2012, Versailles, France
Communication dans un congrès hal-02747277v1

Human MuStem cells, a promising therapeutic candidate for muscular dystrophies with immunomodulatory properties

Judith Lorant , Nicolas Jaulin , Marine Charrier , Blandine Lieubeau-Teillet , Isabelle Leroux
Nantes Actualités Transplantation, Jun 2016, Nantes, France. 2016
Poster de conférence hal-01595625v1

Human MuStem cells: a cell-based therapy candidate for Duchenne Muscular Dystrophy, with immunomodulatory properties.

Judith Lorant , Nicolas Jaulin , Isabelle Leroux , Céline Zuber , Cindy Schleder
5th International congress of Myology, 2016, Lyon, France. 2016
Poster de conférence hal-02740840v1
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Immunomodulatory properties of human MuStem cells: assessing their impact on adaptive and innate immunity

Judith Lorant , Nicolas Jaulin , Isabelle Leroux , Cindy Schleder , Céline Zuber
ESGCT and FSGT Collaborative Congress, Sep 2015, Helsinki, Finland. Human Gene Therapy, 26 (10), 2015, Human Gene Therapy
Poster de conférence hal-01242346v1

In vitro and in vivo characterization of immunomodulatory properties of MuStem cells

Judith Lorant , Nicolas Jaulin , Thibaut T. Larcher , Benoît Hédan , Jack-Yves Deschamps
Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), Oct 2014, The Hague, Netherlands. 2014
Poster de conférence hal-02742740v1
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Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune response

Gwaldys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud
16th annual meeting, May 2013, Salt Lake City, United States. 2013
Poster de conférence hal-01190314v1