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14

Nicolas JAULIN


Team Immunologie du transfert de gène & Gene therapy immunology Core

Inserm UMR 1089 - Translationnal Gene Therapy for Genetic Diseases

 

nicolas.jaulin@univ-nantes.fr

+33 28 08 04 53


Journal articles7 documents

  • Celine Vandamme, Rebecca Xicluna, Leslie Hesnard, Marie Devaux, Nicolas Jaulin, et al.. Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation. Frontiers in Immunology, Frontiers, 2020, 10, pp.3110. ⟨10.3389/fimmu.2019.03110⟩. ⟨inserm-02447186⟩
  • Mickaël Guilbaud, Marie Devaux, Célia Couzinié, Johanne Le Duff, Alice Toromanoff, et al.. 5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity. Human Gene Therapy, Mary Ann Liebert, 2019. ⟨inserm-02052292⟩
  • Pauline Schmit, Simon Pacouret, Eric Zinn, Elizabeth Telford, Fotini Nicolaou, et al.. Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries. Molecular Therapy - Methods and Clinical Development, Nature Publishing Group, 2019, 17, pp.107-121. ⟨10.1016/j.omtm.2019.11.014⟩. ⟨inserm-02448091⟩
  • Judith Lorant, Thibaut Larcher, Nicolas Jaulin, Benoit Hedan, Aurélie Lardenois, et al.. Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits. Cell Transplantation, Cognizant Communication Corporation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩. ⟨hal-01812518⟩
  • Gwaldys Gernoux, Mickaël Guilbaud, Laurence Dubreil, Thibaut Larcher, Candice Babarit, et al.. Early interaction of AAV8 with the host immune system following intramuscular delivery results in weak but detectable lymphocyte and dendritic cell transduction. Human Gene Therapy, Mary Ann Liebert, 2015. ⟨hal-02631159⟩
  • Gwladys Gernoux, Mickaël Guilbaud, Laurence Dubreil, Thibaut Larcher, Candice Babarit, et al.. Early Interaction of Adeno-Associated Virus Serotype 8 Vector with the Host Immune System Following Intramuscular Delivery Results in Weak but Detectable Lymphocyte and Dendritic Cell Transduction. Human Gene Therapy, Mary Ann Liebert, 2015, 26 (1), pp.1 - 13. ⟨10.1089/hum.2014.070⟩. ⟨inserm-01734763⟩
  • A Moreau, C Vandamme, Mercedes Segovia, M. Devaux, Mickaël Guilbaud, et al.. Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer.. Mol Ther Methods Clin Dev, 2014, 1. ⟨hal-01222897⟩

Conference papers2 documents

  • Gwladys Gernoux, Marie Devaux, Laurence Dubreil, Nicolas Jaulin, Mickaël Guilbaud, et al.. Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune responses. 16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States. ⟨hal-02749165⟩
  • Gwladys Gernoux, Marie Devaux, Laurence Dubreil, Nicolas Jaulin, Mickaël Guilbaud, et al.. Macaque immune responses following AAV-based gene transfer to the skeletal muscle: addressing the method of vector delivery. European Society of Gene and Cell Therapy/French Society of Cell and Gene Therapy Collaborative Congress, Oct 2012, Versailles, France. ⟨hal-02747277⟩

Poster communications5 documents

  • Judith Lorant, Nicolas Jaulin, Marine Charrier, Blandine Lieubeau-Teillet, Isabelle Leroux, et al.. Human MuStem cells, a promising therapeutic candidate for muscular dystrophies with immunomodulatory properties. Nantes Actualités Transplantation, Jun 2016, Nantes, France. 2016. ⟨hal-01595625⟩
  • Judith Lorant, Nicolas Jaulin, Isabelle Leroux, Céline Zuber, Cindy Schleder, et al.. Human MuStem cells: a cell-based therapy candidate for Duchenne Muscular Dystrophy, with immunomodulatory properties.. 5th International congress of Myology, 2016, Lyon, France. 2016. ⟨hal-02740840⟩
  • Judith Lorant, Nicolas Jaulin, Isabelle Leroux, Cindy Schleder, Céline Zuber, et al.. Immunomodulatory properties of human MuStem cells: assessing their impact on adaptive and innate immunity. ESGCT and FSGT Collaborative Congress, Sep 2015, Helsinki, Finland. Human Gene Therapy, 26 (10), 2015, Human Gene Therapy. ⟨hal-01242346⟩
  • Judith Lorant, Nicolas Jaulin, Thibaut Larcher, Benoît Hédan, Jack-Yves Deschamps, et al.. In vitro and in vivo characterization of immunomodulatory properties of MuStem cells. Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), Oct 2014, The Hague, Netherlands. 2014. ⟨hal-02742740⟩
  • Gwaldys Gernoux, Marie Devaux, Laurence Dubreil, Nicolas Jaulin, Mickaël Guilbaud, et al.. Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune response. 16th annual meeting, May 2013, Salt Lake City, United States. 2013. ⟨hal-01190314⟩