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Crystal structure and functional domains of the Mambaquaretin-1, a vasopressin type 2 receptor peptide inhibitor for kidney cysts treatment

Laura Droctové , Justyna Ciolek , Manon Lancien , Enrico Stura , Laura Vera , et al.
Toxicon, 2018, 149, pp.91-92. ⟨10.1016/j.toxicon.2017.12.021⟩
Article dans une revue hal-03572739v1

Structure-function relationships of elastin-derived peptides: determination of a structural motif involved in the peptides-receptor(s) interactions.

Nicolas Floquet , Laurent Duca , Stéphanie Héry-Hyunh , Gauthier Moroy , Manuel Dauchez , et al.
Elastin 2002, 2003
Chapitre d'ouvrage hal-02333101v1

Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a

C. Goze , Gilbert Berge , Celine M\'Kadmi , Nicolas Floquet , Didier Gagne , et al.
European Journal of Pharmacology Molecular Pharmacology, 2010, 643 (2-3), pp.153-161. ⟨10.1016/j.ejphar.2010.06.018⟩
Article dans une revue istex hal-00583009v1

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor.

Sophie Mary , Marjorie Damian , Maxime Louet , Nicolas Floquet , Jean-Alain Fehrentz , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (21), pp.8304-9. ⟨10.1073/pnas.1119881109⟩
Article dans une revue hal-00713574v1

The YSNSG cyclopeptide derived from tumstatin inhibits tumor angiogenesis by down-regulating endothelial cell migration

Jessica Thévenard , Laurent Ramont , Bertrand Brassart , Aurélie Dupont-Deshorgue , Nicolas Floquet , et al.
International Journal of Cancer, 2010, 126 (5), pp.1055-1066
Article dans une revue hal-00771934v1

A Concerted Mechanism for Opening the GDP Binding Pocket and Release of the Nucleotide in Hetero-Trimeric G-Proteins

Maxime Louet , David Perahia , Jean Martinez , Nicolas Floquet
Journal of Molecular Biology, 2011, 411, pp.296-312. ⟨10.1016/j.jmb.2011.05.034⟩
Article dans une revue istex hal-00771168v1

Expanding the borononucleotide family: synthesis of borono-analogues of dCMP, dGMP and dAMP.

Anthony R. Martin , Kishor Mohanan , Delphine Luvino , Nicolas Floquet , Carine Baraguey , et al.
Organic & Biomolecular Chemistry, 2009, 7 (21), pp.4369-4377. ⟨10.1039/b912616c⟩
Article dans une revue istex hal-01109915v1

Conformational restriction of G-proteins Coupled Receptors (GPCRs) upon complexation to G-proteins: A putative activation mode of GPCRs?

Maxime Louet , Esra Karakas , Alexandre Perret , David Perahia , Jean Martinez , et al.
FEBS Letters, 2013, 587 (16), pp.2656-2661. ⟨10.1016/j.febslet.2013.06.052⟩
Article dans une revue hal-01107226v1

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.

Marjorie Damian , Sophie Mary , Mathieu Maingot , Céline M'Kadmi , Didier Gagne , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (5), pp.1601-1606. ⟨10.1073/pnas.1414618112⟩
Article dans une revue hal-01115392v1

L-Arginine Binding to Human Inducible Nitric Oxide Synthase: An Antisymmetric Funnel Route toward Isoform-Specific Inhibitors?

Nicolas Floquet , Jean-François Hernandez , Jean-Luc Boucher , Jean Martinez
Journal of Chemical Information and Modeling, 2011, 51, pp.1325-1335. ⟨10.1021/ci100422v⟩
Article dans une revue hal-00770855v1

Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain

Guillaume Ferré , Maxime Louet , Oliver Saurel , Bartholomé Delort , Georges Czaplicki , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (35), pp.17525-17530. ⟨10.1073/pnas.1905105116⟩
Article dans une revue hal-02322092v1

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

Marjorie Damian , Véronique Pons , Pedro Renault , Céline M’kadmi , Bartholomé Delort , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (17), pp.4501-4506. ⟨10.1073/pnas.1712725115⟩
Article dans une revue hal-02322168v1
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Sodium is a negative allosteric regulator of the ghrelin receptor

Guillaume Ferré , Antoniel A.S. Gomes , Maxime Louet , Marjorie Damian , Paulo Bisch , et al.
Cell Reports, 2023, 42 (4), pp.112320. ⟨10.1016/j.celrep.2023.112320⟩
Article dans une revue hal-04265315v1

Structural and antitumor properties of the YSNSG cyclopeptide derived from Tumstatin

Jessica Thévenard , Nicolas Floquet , Laurent Ramont , Elise Prost , Jean-Marc Nuzillard , et al.
Chemistry & biology, 2006, 13, pp.1307-1315
Article dans une revue hal-00134047v1
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Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor

Maxime Louet , Marina Casiraghi , Marjorie Damian , Mauricio Gs Costa , Pedro Renault , et al.
eLife, 2021, 10, ⟨10.7554/elife.63201⟩
Article dans une revue hal-03407524v1

Human thrombospondin’s (TSP-1) C-terminal domain opens to interact with the CD-47 receptor: A molecular modeling study

Nicolas Floquet , Stéphane Dedieu , Laurent Martiny , Manuel Dauchez , David Perahia
Archives of Biochemistry and Biophysics, 2008, 478 (1), pp.103-109. ⟨10.1016/j.abb.2008.07.015⟩
Article dans une revue istex hal-01109933v1

Elastin in silico.

Alain J.P. Alix , Brigida Bochicchio , Manuel Dauchez , Laurent Debelle , Philippe Derreumaux , et al.
Second European Symposium ELASTIN 2002, Jul 2002, Acquafredda di Maratea, Italy
Communication dans un congrès hal-02333204v1

Coarse-Grained Prediction of Peptide Binding to G-Protein Coupled Receptors

Bartholomé Delort , Pedro Renault , Landry Charlier , Florent Raussin , Jean Martinez , et al.
Journal of Chemical Information and Modeling, 2017, 57 (3), pp.562-571. ⟨10.1021/acs.jcim.6b00503⟩
Article dans une revue hal-02322212v1

Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes

Nicolas Floquet , Mauricio g.S. Costa , Paulo r. Batista , Pedro Renault , Paulo m. Bisch , et al.
Biophysical Journal, 2015, 109 (6), pp.1179-1189. ⟨10.1016/j.bpj.2015.07.003⟩
Article dans une revue hal-02322259v1

Structure and Dynamics of the Receptor-Bound Ghrelin Lipopeptide

Guillaume Ferré , Marjorie Damian , Céline M'Kadmi , Olivier Saurel , Georges Czaplicki , et al.
Biophysical Journal, 2018, 114 (3), pp.235a. ⟨10.1016/J.BPJ.2017.11.1308⟩
Article dans une revue hal-02405941v1

Nos récepteurs déroulent leur mécanique !

Maxime Louet , Landry Charlier , Jean Martinez , Nicolas Floquet
2013, pp.380:26
Autre publication scientifique hal-01105310v1

Coarse-Grained Simulations of the HIV-1 Matrix Protein Anchoring: Revisiting Its Assembly on Membrane Domains.

Landry Charlier , Maxime Louet , Laurent Chaloin , Patrick Fuchs , Jean Martinez , et al.
Biophysical Journal, 2014, 106 (3), pp.577-585. ⟨10.1016/j.bpj.2013.12.019⟩
Article dans une revue hal-01105330v1

Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues

Roberto Fanelli , Nicolas Floquet , Élie Besserer-Offroy , Bartholomé Delort , Mélanie Vivancos , et al.
Journal of Medicinal Chemistry, 2017, 60 (8), pp.3303-3313. ⟨10.1021/acs.jmedchem.6b01848⟩
Article dans une revue hal-02322191v1
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MDexciteR: Enhanced Sampling Molecular Dynamics by Excited Normal Modes or Principal Components Obtained from Experiments

Mauricio Costa , Paulo R Batista , Antoniel Gomes , Leonardo S Bastos , Maxime Louet , et al.
Journal of Chemical Theory and Computation, 2023, 19 (2), pp.412-425. ⟨10.1021/acs.jctc.2c00599⟩
Article dans une revue hal-04277555v1

Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations

Nicolas Floquet , Celine Richez , Philippe Durand , Bernard Maigret , Bernard Badet , et al.
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (7), pp.1966-1970. ⟨10.1016/j.bmcl.2007.01.052⟩
Article dans une revue istex hal-02144683v1
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GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins.

Maxime Louet , Jean Martinez , Nicolas Floquet
PLoS Computational Biology, 2012, 8 (7), pp.e1002595. ⟨10.1371/journal.pcbi.1002595⟩
Article dans une revue hal-01109342v1

Activation of the Ghrelin Receptor is Described by a Privileged Collective Motion: A Model for Constitutive and Agonist-induced Activation of a Sub-class A G-Protein Coupled Receptor (GPCR)

Nicolas Floquet , C. Mikadmi , D. Perahia , Didier Gagne , Gilbert Berge , et al.
Journal of Molecular Biology, 2010, 395 (4), pp.769-784. ⟨10.1016/j.jmb.2009.09.051⟩
Article dans une revue istex hal-00485751v1
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Interaction between the Elastin Peptide VGVAPG and Human Elastin Binding Protein

Charlotte Blanchevoye , Nicolas Floquet , Amandine Scandolera , Stéphanie Baud , Pascal Maurice , et al.
Journal of Biological Chemistry, 2013, 288 (2), pp.1317-1328. ⟨10.1074/jbc.M112.419929⟩
Article dans une revue hal-02347668v1
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Identification of TAX2 peptide as a new unpredicted anti-cancer agent

Albin Jeanne , Emilie Sick , Jerôme Devy , Nicolas Floquet , N. Belloy , et al.
Oncotarget, 2015, 6, pp.17981-18000. ⟨10.18632/oncotarget.4025⟩
Article dans une revue hal-01280451v1
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Interaction between the elastin peptide VGVAPG and human elastin binding protein.

Charlotte Blanchevoye , Nicolas Floquet , Amandine Scandolera , Stéphanie Baud , Pascal Maurice , et al.
Journal of Biological Chemistry, 2013, 288 (2), pp.1317-1328. ⟨10.1074/jbc.M112.419929⟩
Article dans une revue hal-01109325v1