Nathalie Sibille

Documents

Présentation

Domaines de recherche

Compétences

Publications

	Charge-Governed Solvation Behaviour of Novel AMPs Peicho Petkov , Rositsa Marinova , Leandar Litov , Elena Lilkova , Frédéric Allemand 2023 Pré-publication, Document de travail hal-04279854v1
	Charge-Governed Solvation Behaviour of Novel AMPs Peicho Petkov , Rositsa Marinova , Leandar Litov , Elena Lilkova , Frédéric Allemand 2023 Pré-publication, Document de travail hal-04274303v2
	The structure of pathogenic huntingtin exon-1 defines the bases of its aggregation propensity Carlos A Elena-Real , Amin Sagar , Annika Urbanek , Matija Popovic , Anna Morató 2022 Pré-publication, Document de travail hal-03846359v1
	A CDK-mediated phosphorylation switch of disordered protein condensation Juan Valverde , Geronimo Dubra , Henk W.P. van Den Toorn , Guido Van Mierlo , Michiel Vermeulen 2022 Pré-publication, Document de travail hal-03845313v1
	Multivalent interactions between eIF4G1, Pub1 and Pab1 drive the formation of protein condensates Belén Chaves-Arquero , Santiago Martínez-Lumbreras , Nathalie Sibille , Sergio Camero , Pau Bernadó 2020 Pré-publication, Document de travail hal-03047229v1

	A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation Juan Manuel Valverde , Geronimo Dubra , Michael Phillips , Austin Haider , Carlos Elena-Real Nature Communications, 2023, 14 (1), pp.6316. ⟨10.1038/s41467-023-42049-0⟩ Article dans une revue hal-04239889v1
	Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction Myriam Guillien , Assia Mouhand , Amin Sagar , Aurélie Fournet , Frédéric Allemand Structure, 2023, 31 (11), pp.1394-1406.e7. ⟨10.1016/j.str.2023.08.011⟩ Article dans une revue hal-04235502v1
	Structure–function relationships in protein homorepeats Carlos Elena-Real , Pablo Mier , Nathalie Sibille , Miguel Andrade-Navarro , Pau Bernadó Current Opinion in Structural Biology, 2023, 83, pp.102726. ⟨10.1016/j.sbi.2023.102726⟩ Article dans une revue hal-04269590v1
	A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling Pauline Raynaud , Vinesh Jugnarain , Océane Vaugrente , Amandine Vallet , Thomas Boulo FEBS Letters, 2023, 598 (2), pp.220-232. ⟨10.1002/1873-3468.14765⟩ Article dans une revue hal-04269864v1
	Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex Julien Bous , Aurélien Fouillen , Hélène Orcel , Stefano Trapani , Xiaojing Cong Science Advances , 2022, 8 (35), pp.eabo7761. ⟨10.1126/sciadv.abo7761⟩ Article dans une revue hal-03790728v1
	eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1 and self-assembly Belén Chaves-Arquero , Santiago Martínez-Lumbreras , Nathalie Sibille , Sergio Camero , Pau Bernadó Frontiers in Molecular Biosciences, 2022, ⟨10.3389/fmolb.2022.986121⟩ Article dans une revue hal-03763836v1
	Structural Insights into the Intrinsically Disordered GPCR C:Terminal Region, Major Actor in Arrestin:GPCR Interaction Myriam Guillien , Assia Mouhand , Aurelie Fournet , Amandine Gontier , Aleix Martí Navia Biomolecules, 2022, 12 (5), pp.617. ⟨10.3390/biom12050617⟩ Article dans une revue hal-03748408v1
	The diversity of molecular interactions involving intrinsically disordered proteins: A molecular modeling perspective Ilinka Clerc , Amin Sagar , Alessandro Barducci , Nathalie Sibille , Pau Bernadó Computational and Structural Biotechnology Journal, 2021, 19, pp.3817-3828. ⟨10.1016/j.csbj.2021.06.031⟩ Article dans une revue hal-03281983v1
	Structural insights into the cooperative interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR) Lucile Senicourt , Albane Le Maire , Frédéric Allemand , João E Carvalho , Laura Guee Journal of Molecular Biology, 2021, ⟨10.1016/j.jmb.2021.166899⟩ Article dans une revue hal-03047222v2
	Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells Nikola Arsic , Tania Slatter , Gilles Gadea , Etienne Villain , Aurelie Fournet Nature Communications, 2021, 12 (1), pp.5463. ⟨10.1038/s41467-021-25550-2⟩ Article dans une revue hal-03346748v1
	IDPs and their complexes in GPCR and nuclear receptor signaling Myriam Guillien , Albane Le Maire , Assia Mouhand , Pau Bernadó , William Bourguet Progress in Molecular Biology and Translational Science, 2020, Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, 174, pp.105 - 155. ⟨10.1016/bs.pmbts.2020.05.001⟩ Article dans une revue hal-03749862v1
	Predicting secondary structure propensities in IDPs using simple statistics from three-residue fragments Alejandro N Estaña , Amélie Barozet , Assia Mouhand , Marc Vaisset , Christophe Zanon Journal of Molecular Biology, 2020, 342 (19), pp.5447-5459. ⟨10.1016/j.jmb.2020.07.026⟩ Article dans une revue hal-02920302v1
	Evidence of the reduced abundance of proline cis conformation in protein poly-proline tracts Annika N Urbanek , Matija Popovic , Carlos A Elena-Real , Anna Morató , Alejandro N Estaña Journal of the American Chemical Society, 2020, 142 (17), pp.7976-7986. ⟨10.1021/jacs.0c02263⟩ Article dans une revue hal-02545935v1
	Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins Anna Morató , Carlos Elena-Real , Matija Popovic , Aurélie Fournet , Karen Zhang Biomolecules, 2020, 10 (10), pp.1458. ⟨10.3390/biom10101458⟩ Article dans une revue hal-03047216v1
	Flanking regions determine the structure of the poly-glutamine homo- repeat in huntingtin through mechanisms common among glutamine-rich human proteins Annika N Urbanek , Matija Popovic , Anna Morató , Alejandro N Estaña , Carlos A Elena-Real Structure, 2020, 28 (7), pp.733-746.e5. ⟨10.1016/j.str.2020.04.008⟩ Article dans une revue hal-02893075v1
	Site‐Specific Isotopic Labeling (SSIL) – Access to High‐Resolution Structural and Dynamic Information in Low Complexity Proteins Annika N Urbanek , Carlos A Elena-Real , Matija Popovic , Anna Morató , Aurélie Fournet ChemBioChem, 2019, ⟨10.1002/cbic.201900583⟩ Article dans une revue hal-02359756v1
	Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression Tiago N Cordeiro , Nathalie Sibille , Pierre Germain , Philippe Barthe , Abdelhay Boulahtouf Structure, 2019, 27 (8), pp.1270-1285.e6. ⟨10.1016/j.str.2019.05.001⟩ Article dans une revue hal-03078485v1
	Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database Alejandro N Estaña , Nathalie Sibille , Elise Delaforge , Marc Vaisset , Juan Cortés Structure, 2019, 27 (5), pp.381-391.e2. ⟨10.1016/j.str.2018.10.016⟩ Article dans une revue hal-01954977v1
	A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats Annika N Urbanek , Anna Morató , Frédéric Allemand , Elise Delaforge , Aurélie Fournet Angewandte Chemie International Edition, 2018, ⟨10.1002/anie.201711530⟩ Article dans une revue hal-01737188v1
	Hybrid parallelization of a multi-tree path search algorithm: Application to highly-flexible biomolecules Alejandro N Estaña , Kevin Molloy , Marc Vaisset , Nathalie Sibille , Thierry Simeon Parallel Computing, 2018, 77, pp.84-100. ⟨10.1016/j.parco.2018.06.005⟩ Article dans une revue hal-01823694v2
	Structural Characterization of Highly Flexible Proteins by Small-Angle Scattering. Tiago N Cordeiro , Fatima Herranz-Trillo , Annika N Urbanek , Alejandro N Estaña , Juan Cortés Advances in Experimental Medicine and Biology, 2017, pp.PP.107-129. ⟨10.1007/978-981-10-6038-0_7⟩ Article dans une revue hal-01664316v1
	Disentangling polydispersity in the PCNA−p15PAF complex, a disordered, transient and multivalent macromolecular assembly Tiago N Cordeiro , Po-Chia Chen , Alfredo De biasio , Nathalie Sibille , Francisco Blanco Nucleic Acids Research, 2017, 45 (3), pp.1501-1515. ⟨10.1093/nar/gkw1183⟩ Article dans une revue hal-02348011v1
	p15(PAF) Is an Intrinsically Disordered Protein with Nonrandom Structural Preferences at Sites of Interaction with Other Proteins. Alfredo de Biasio , Alain Ibáñez de Opakua , Tiago N Cordeiro , Maider Villate , Nekane Merino Biophysical Journal, 2014, 106 (4), pp.865-874. ⟨10.1016/j.bpj.2013.12.046⟩ Article dans une revue hal-00967481v1
	Measuring residual dipolar couplings at high hydrostatic pressure: robustness of alignment media to high pressure Nathalie Sibille , Mariano Dellarole , Catherine A. Royer , Christian Roumestand Journal of Biomolecular NMR, 2014, 58 (1), pp.9-16. ⟨10.1007/s10858-013-9798-7⟩ Article dans une revue hal-02347973v1
	Low concentration of a Gd-chelate increases the signal-to-noise ratio in fast pulsing BEST experiments Nathalie Sibille , Gaëtan Bellot , Jing Wang , Hélène Déméné Journal of Magnetic Resonance, 2012, 224, pp.32-37. ⟨10.1016/j.jmr.2012.07.022⟩ Article dans une revue hal-02347955v1
	Structural characterization of intrinsically disordered proteins by the combined use of NMR and SAXS Nathalie Sibille , Pau Bernadó Biochemical Society Transactions, 2012, 40 (5), pp.955-962. ⟨10.1042/BST20120149⟩ Article dans une revue hal-02347934v1
	Oleuropein and derivatives from olives as Tau aggregation inhibitors. Anthony Daccache , Cedric Lion , Nathalie Sibille , Melanie Gerard , Christian Slomianny Neurochemistry International, 2011, 58 (6), pp.700-7. ⟨10.1016/j.neuint.2011.02.010⟩ Article dans une revue hal-00586934v1
	Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein. Nathalie Sibille , Isabelle Huvent , Caroline Fauquant , Dries Verdegem , Laziza Amniai Proteins - Structure, Function and Bioinformatics, 2011, epub ahead of print. ⟨10.1002/prot.23210⟩ Article dans une revue hal-00713027v1
	NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease. Isabelle Landrieu , Arnaud Leroy , Caroline Smet-Nocca , Isabelle Huvent , Laziza Amniai Biochemical Society Transactions, 2010, 38 (4), pp.1006-11. ⟨10.1042/BST0381006⟩ Article dans une revue hal-00586933v1
	Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025. Isabelle Landrieu , Xavier Hanoulle , Fanny Bonachera , Arnaud Hamel , Nathalie Sibille Biochemistry, 2010, 49 (22), pp.4679-86. ⟨10.1021/bi1003266⟩ Article dans une revue hal-00508817v1
	Selective backbone labelling of ILV methyl labelled proteins. Nathalie Sibille , Xavier Hanoulle , Fanny Bonachera , Dries Verdegem , Isabelle Landrieu Journal of Biomolecular NMR, 2009, 43 (4), pp.219-27. ⟨10.1007/s10858-009-9307-1⟩ Article dans une revue hal-00373458v1
	Tau aggregation in Alzheimer's disease : what role for phosphorylation ? Guy Lippens , Alain Sillen , Isabelle Landrieu , Laziza Amniai , Nathalie Sibille Prion, 2007, 1 (1), pp.21-25 Article dans une revue hal-00161158v1
	Structural and functional characterisation of the interaction between cyclophilin B and A heparin derived oligosaccharide. Xavier Hanoulle , Aurélie Melchior , Nathalie Sibille , Benjamin Parent , Agnès Denys Journal of Biological Chemistry, 2007, epub ahead of print. ⟨10.1074/jbc.M706353200⟩ Article dans une revue hal-00175485v1
	NMR analysis of a Tau phosphorylation pattern. Isabelle Landrieu I , Ludovic Lacosse , Arnaud Leroy , Jean-Michel Wieruszeski , Xavier Trivelli Journal of the American Chemical Society, 2006, 128, pp.3575-3583 Article dans une revue hal-00085610v1
	Structural Impact of Heparin Binding to Full-Length Tau As Studied by NMR Spectroscopy. Nathalie Sibille , Alain Sillen , Arnaud Leroy , Jean-Michel Wieruszeski , Barbara Mulloy Biochemistry, 2006, 45, pp.12560-12572 Article dans une revue hal-00108261v1
	Comparative NMR study on the impact of point mutations on protein stability of Pseudomonas mendocina lipase Nathalie Sibille , Adrien Favier , Ana Azuaga , Grant Ganshaw , Richard Bott Protein Science, 2006, 15 (8), pp.1915-1927. ⟨10.1110/ps.062213706⟩ Article dans une revue hal-02347920v1
	Solution Structure of the Sulfite Reductase Flavodoxin-like Domain from Escherichia coli † , ‡ Nathalie Sibille , Martin Blackledge , Bernhard Brutscher , Jacques Covès , Beate Bersch Biochemistry, 2005, 44 (25), pp.9086-9095. ⟨10.1021/bi050437p⟩ Article dans une revue hal-02347867v1
	Reactivity, Secondary Structure, and Molecular Topology of the Escherichia coli Sulfite Reductase Flavodoxin-like Domain † Nathalie Sibille , Ludovic Champier , Beate Bersch , Bernhard Brutscher , Martin Blackledge Biochemistry, 2002, 41 (11), pp.3770-3780. ⟨10.1021/bi016008i⟩ Article dans une revue hal-02347845v1
	Side Chain Orientation from Methyl 1 H− 1 H Residual Dipolar Couplings Measured in Highly Deuterated Proteins Nathalie Sibille , Beate Bersch , Jacques Covès , Martin Blackledge , Bernhard Brutscher Journal of the American Chemical Society, 2002, 124 (49), pp.14616-14625. ⟨10.1021/ja020888m⟩ Article dans une revue hal-02347862v1
	1H, 13C and 15N assignment of the flavodoxin-like domain of the Escherichia coli sulfite reductase Nathalie Sibille , Jacques Covès , Dominique Marion , Bernhard Brutscher , Beate Bersch Journal of Biomolecular NMR, 2001, 21 (1), pp.71-72. ⟨10.1023/a:1011985803535⟩ Article dans une revue hal-02347783v1
	Refinement of Local and Long-Range Structural Order in Theophylline-Binding RNA Using 13 C− 1 H Residual Dipolar Couplings and Restrained Molecular Dynamics Nathalie Sibille , Arthur Pardi , Jean-Pierre Simorre , Martin Blackledge Journal of the American Chemical Society, 2001, 123 (49), pp.12135-12146. ⟨10.1021/ja011646+⟩ Article dans une revue hal-02347823v1

	Conformational Characterization of Intrinsically Disordered Proteins and Its Biological Significance Elise Delaforge , Tiago N Cordeiro , Pau Bernadó , Nathalie Sibille Graham A. Webb. Modern Magnetic Resonance, Springer International Publishing, pp.381-399, 2018, 978-3-319-28387-6. ⟨10.1007/978-3-319-28388-3_52⟩ Chapitre d'ouvrage hal-02348118v1

	Désordre Fonctionnel dans les Mécanismes Moléculaires de régulation de la Signalisation Cellulaire Nathalie Sibille Sciences du Vivant [q-bio]. Université de Montpellier, 2021 HDR tel-03883914v1

Nathalie Sibille

Présentation

Domaines de recherche

Compétences

Publications

Charge-Governed Solvation Behaviour of Novel AMPs

Charge-Governed Solvation Behaviour of Novel AMPs

The structure of pathogenic huntingtin exon-1 defines the bases of its aggregation propensity

A CDK-mediated phosphorylation switch of disordered protein condensation

Multivalent interactions between eIF4G1, Pub1 and Pab1 drive the formation of protein condensates

A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation

Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction

Structure–function relationships in protein homorepeats

A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling

Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex

eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1 and self-assembly

Structural Insights into the Intrinsically Disordered GPCR C:Terminal Region, Major Actor in Arrestin:GPCR Interaction

The diversity of molecular interactions involving intrinsically disordered proteins: A molecular modeling perspective

Structural insights into the cooperative interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR)

Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells

IDPs and their complexes in GPCR and nuclear receptor signaling

Predicting secondary structure propensities in IDPs using simple statistics from three-residue fragments

Evidence of the reduced abundance of proline cis conformation in protein poly-proline tracts

Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins

Flanking regions determine the structure of the poly-glutamine homo- repeat in huntingtin through mechanisms common among glutamine-rich human proteins

Site‐Specific Isotopic Labeling (SSIL) – Access to High‐Resolution Structural and Dynamic Information in Low Complexity Proteins

Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression

Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database

A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats

Hybrid parallelization of a multi-tree path search algorithm: Application to highly-flexible biomolecules

Structural Characterization of Highly Flexible Proteins by Small-Angle Scattering.

Disentangling polydispersity in the PCNA−p15PAF complex, a disordered, transient and multivalent macromolecular assembly

p15(PAF) Is an Intrinsically Disordered Protein with Nonrandom Structural Preferences at Sites of Interaction with Other Proteins.

Measuring residual dipolar couplings at high hydrostatic pressure: robustness of alignment media to high pressure

Low concentration of a Gd-chelate increases the signal-to-noise ratio in fast pulsing BEST experiments

Structural characterization of intrinsically disordered proteins by the combined use of NMR and SAXS

Oleuropein and derivatives from olives as Tau aggregation inhibitors.

Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein.

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease.

Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.

Selective backbone labelling of ILV methyl labelled proteins.

Tau aggregation in Alzheimer's disease : what role for phosphorylation ?

Structural and functional characterisation of the interaction between cyclophilin B and A heparin derived oligosaccharide.

NMR analysis of a Tau phosphorylation pattern.

Structural Impact of Heparin Binding to Full-Length Tau As Studied by NMR Spectroscopy.

Comparative NMR study on the impact of point mutations on protein stability of Pseudomonas mendocina lipase

Solution Structure of the Sulfite Reductase Flavodoxin-like Domain from Escherichia coli † , ‡

Reactivity, Secondary Structure, and Molecular Topology of the Escherichia coli Sulfite Reductase Flavodoxin-like Domain †

Side Chain Orientation from Methyl 1 H− 1 H Residual Dipolar Couplings Measured in Highly Deuterated Proteins

1H, 13C and 15N assignment of the flavodoxin-like domain of the Escherichia coli sulfite reductase

Refinement of Local and Long-Range Structural Order in Theophylline-Binding RNA Using 13 C− 1 H Residual Dipolar Couplings and Restrained Molecular Dynamics

Conformational Characterization of Intrinsically Disordered Proteins and Its Biological Significance

Désordre Fonctionnel dans les Mécanismes Moléculaires de régulation de la Signalisation Cellulaire