Nathalie Mignet

106

Documents

Présentation

CNRS Research Director National Scientific Research Center (CNRS) - France. Born 01/10/1970 •Leader of the laboratory: UTCBS: Unité des Technologies Chimiques et Biologiques pour la Santé Team Leader of the team Vector for Molecular Imaging and targeted therapy in UTCBS Université de Paris - UMR 8258 - CNRS – UMR-S 1267 Inserm **Main scientific field and domain of competence**: - Nanomedicine, non viral vectors for gene delivery, liposomes - Biomaterials - Drug delivery - Cancer therapy – Nanovectors characterisation – Bioimaging, optical imaging techniques. - Main work patents and discoveries concern gene delivery vectors, including chemical vectors delivery methods, new characterisation methods, pharmacokinetic and bioimaging. ****Scientific Publications:**** - h index: 30 (1997-) - 3351 quotations - 86 articles in reviewed journals or book chapters. - 26 reviews or books chapters - 11 independent patent applications - 26 invited speaker lectures in International Meetings - Editor for Elsevier of 3 special issues in International Journal of Pharmaceutics, 2 for Frontiers in chemistry - Editorial Board of Nanomedicine, Drug Delivery and Translational Research, Pharmaceutics, Nanotheranostics **Diplomas** - 2008: Habilitation to lead research - 1996: PhD in bio-organic chemistry, montpellier, France **Scientific Responsibilities (present time):** - 2019-ongoing: Lab leader: UTCBS - 2014 – ongoing: Team Leader Vectors for Molecular Imaging and Targeted Therapies - 2019- Member of the ITMO Heath Technologies Council - 2014-2020: Founder and president of the French Society for Nanomedicine - 2021- Elected Member of the INSERM Scientific commission - 2021-Committee Member for the National Research Agency - 2017-2018: Committee member for the National Council Research of Norway - 2015-2019: Committee Member for the National Ligue against Cancer (La Ligue) - 2013-2016: Committee member for the national Research Agency. - 2017: Working Group member on Nanomedicine for the Alliance Aviesan - 2016 Working group member for the Pharmaceutical center prospective 10 Major publications: 1. V. Baldim, F. Bedioui, N. Mignet, I. Margaill, J.-F. Berret Ce3+-surface density superposition principle observed for CeO2-x superoxide dismutase and catalase-like catalytic activities Nanoscale 2018, 10(15):6971-6980. 2\. Zeng N., Seguin J., Dumortier G., Maury M., Bessodes M., Scherman D., Mignet N., Boudy V. Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: in vitro and in vivo validation of a sustained buccal drug delivery Int J Pharm 2017, 534(1-2):128-135. 3\. Ramírez-García G, Gutiérrez-Granados S, Gallegos-Corona MA, Palma-Tirado L, d'Orlyé F, Varenne A, Mignet N, Richard C, Martínez-Alfaro M. Long-term toxicological effects of persistent luminescence nanoparticles after intravenous injection in mice. Int J Pharm. 2017, 532, 686-695. 4 Valero L, Alhareth K, Gil S, Simasotchi C, Roques C, Scherman D, Mignet N, Fournier T, Andrieux K. Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo models: the dually perfused human placenta and the suspended villous explants. Int J Pharm. 2017, 532(2):729-737 5 Manta S, Renault G, Delalande A, Couture O, Lagoutte I, Seguin J, Lager F, Houzé P, Midoux P, Bessodes M, Scherman D, Bureau MF, Marie C, Pichon C, Mignet, N. Cationic Microbubbles and Antibiotic-Free Plasmid for sustained Ultrasound-mediated Transgene Expression in liver. J. Controlled Rel. 2017, 262:170-181 6 Ramírez-García G, d'Orlyé F, Gutiérrez-Granados S, Martínez-Alfaro M, Mignet N, Richard C, Varenne A. Functionalization and characterization of persistent luminescence nanoparticles by dynamic light scattering, laser Doppler and capillary electrophoresis. Colloids Surf B Biointerfaces. 2015, 136, 272-281 7\. Zeng N., Mignet N, Dumortier G, Olivier E, Seguin J, Maury M, Scherman D, Rat P, Boudy V.Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans-epithelial permeability evaluations using TR146 human buccal epithelial cell line International Journal of Pharmaceutics, Int J. Pharm. 2015, 495, 1028-37. 8\. Seguin J, Dhotel H, Kai-Luen R, Bessodes M, Mignet N. Fine tuning of mixed ionic and hydrogen bond interactions for plasmid delivery using lipoplexes. Eur J Pharm Biopharm. 2015, 90, 63-9. 9\. M. Breton, J.F. Berret, C. Bourgaux, T. Kral, M. Hof, C. Pichon, M. Bessodes, D. Scherman, N. Mignet, Protonation of Lipids Impacts the Supramolecular and Biological Properties of Their Self-Assembly. Langmuir, 2011, 27, 12336-45 10\. G. Pembouong, N. Morellet, T. Kral, M. Hof, D. Scherman, M-F. Bureau, N. Mignet, Triblock copolymer L64 destabilizes lipidic membranes and does not interact with DNA J. Controlled Release, 2011, 151, 57-64

Publications

	Zwitterionic Functionalization of Persistent Luminescence Nanoparticles: Physicochemical Characterizations and In Vivo Biodistribution in Mice Delphine Dassonville , Thomas Lécuyer , Johanne Seguin , Yohann Corvis , Jianhua Liu Coatings, 2023, 13 (11), pp.1913. ⟨10.3390/coatings13111913⟩ Article dans une revue hal-04276890v1
	Fate and biological impact of persistent luminescence nanoparticles after injection in mice: a one-year follow-up Thomas Lécuyer , Johanne Seguin , Alice Balfourier , Marine Delagrange , Pierre Bürckel Nanoscale, 2022, 14 (42), pp.15760-15771. ⟨10.1039/D2NR03546D⟩ Article dans une revue hal-03875269v1
	Co-encapsulation of flavonoids with anti–cancer drugs : A challenge ahead Morgane Renault-Mahieux , Nathalie Mignet , Johanne Seguin , Khair Alhareth , Muriel Paul International Journal of Pharmaceutics, 2022, 623, pp.121942. ⟨10.1016/j.ijpharm.2022.121942⟩ Article dans une revue hal-03882629v1
	New Preservative-Free Formulation for the Enhanced Ocular Bioavailability of Prostaglandin Analogues in Glaucoma Gabriel Alviset , Yohann Corvis , Karim Hammad , Josiane Lemut , Marc Maury Pharmaceutics, 2022, 14 (2), pp.453. ⟨10.3390/pharmaceutics14020453⟩ Article dans une revue hal-03705031v1
	In vivo ultrasound modulated optical tomography with a persistent spectral hole burning filter Quang Minh Thai , Ghadir Kalot , Caroline Venet , Johanne Seguin , Maïmouna Bocoum Biomedical optics express, 2022, 13, ⟨10.1364/boe.475449⟩ Article dans une revue hal-03903719v1
	Persistent luminescence nanoparticles functionalized by polymers bearing phosphonic acid anchors: synthesis, characterization, and in vivo behaviour Thomas Lécuyer , Nicolas Bia , Pierre Bürckel , Cédric Loubat , Alain Graillot Nanoscale, 2022, 14 (4), pp.1386-1394. ⟨10.1039/D1NR07114A⟩ Article dans une revue hal-03528462v1
	Influence of Liposomes’ and Lipoplexes’ Physicochemical Characteristics on Their Uptake Rate and Mechanisms by the Placenta Louise Fliedel , Khair Alhareth , Johanne Seguin , Marwa El-Khashab , Audrey Chissey International Journal of Molecular Sciences, 2022, This article belongs to the Special Issue Application Progress of Liposomes in Drug Development, 23 (11), pp.6299. ⟨10.3390/ijms23116299⟩ Article dans une revue hal-04111923v1
	Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy Panpan Ma , Johanne Seguin , Nhu Ky Ly , Luis Castillo-Henríquez , Eva Plansart International Journal of Pharmaceutics: X, 2022, 4, pp.100138. ⟨10.1016/j.ijpx.2022.100138⟩ Article dans une revue hal-04090295v1
	Placental Models for Evaluation of Nanocarriers as Drug Delivery Systems for Pregnancy Associated Disorders Louise Fliedel , Khair Alhareth , Nathalie Mignet , Thierry Fournier , Karine Andrieux Biomedicines, 2022, 10 (5), pp.936. ⟨10.3390/biomedicines10050936⟩ Article dans une revue hal-03712174v1
	How Could Nanomedicine Improve the Safety of Contrast Agents for MRI during Pregnancy? Marinella Difonzo , Louise Fliedel , Nathalie Mignet , Karine Andrieux , Khair Alhareth Sci, 2022, This article belongs to the Special Issue Feature Papers 2021 Editors Collection, 4 (1), pp.11. ⟨10.3390/sci4010011⟩ Article dans une revue hal-04111958v1
	Combination of tumor cell anti-adhesion and anti-tumor effect to prevent recurrence after cytoreductive surgery in a mice model Johanne Seguin , Cynthia Pimpie , Petronille Roy , Chantal Al Sabbagh , Marc Pocard European Journal of Pharmaceutics and Biopharmaceutics, 2021, 169, pp.37-43. ⟨10.1016/j.ejpb.2021.01.020⟩ Article dans une revue hal-03290586v1
	Antioxidant activity and toxicity study of cerium oxide nanoparticles stabilized with innovative functional copolymers Geoffroy Goujon , Victor Baldim , Caroline Roques , Nicolas Bia , Johanne Seguin Advanced Healthcare Materials, 2021, 10 (11), pp.2100059. ⟨10.1002/adhm.202100059⟩ Article dans une revue hal-03452741v1
	Co-Encapsulation of Fisetin and Cisplatin into Liposomes for Glioma Therapy: From Formulation to Cell Evaluation Morgane Renault-Mahieux , Victoire Vieillard , Johanne Seguin , Philippe Espeau , Dang Tri Le Pharmaceutics, 2021, 13, ⟨10.3390/pharmaceutics13070970⟩ Article dans une revue hal-03423934v1
	Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses Mahdi Ftouh , Nesrine Kalboussi , Nabil Abid , Souad Sfar , Nathalie Mignet PPAR Research, 2021, 2021, pp.1-28. ⟨10.1155/2021/6741290⟩ Article dans une revue hal-03423555v1
	Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged Shayan Ahmed , Hugo Salmon , Nicholas Distasio , Hai Doan Do , Daniel Scherman Pharmaceutics, 2021, 13 (4), ⟨10.3390/pharmaceutics13040479⟩ Article dans une revue hal-03290555v1
	Persistent luminescence nanoparticles functionalized by polymers bearing phosphonic acid anchors: synthesis, characterization, and in vivo behaviour Thomas Lécuyer , Nicolas Bia , Pierre Burckel , Cédric Loubat , Alain Graillot Nanoscale, 2021, 14, pp.1386 - 1394. ⟨10.1039/d1nr07114a⟩ Article dans une revue hal-03875283v1
	Electrokinetic elucidation of the interactions between persistent luminescent nanoprobes and the binary apolipoprotein-E/albumin protein system Gonzalo Ramírez García , Fanny d'Orlyé , Cyrille Richard , Nathalie Mignet , Anne Varenne Analyst, 2021, 146 (17), pp.5245-5254. ⟨10.1039/d1an00781e⟩ Article dans une revue hal-03482252v1
	Drug delivery systems to prevent peritoneal metastasis after surgery of digestives or ovarian carcinoma: A review Petronille Roy , Nathalie Mignet , Marc Pocard , Vincent Boudy International Journal of Pharmaceutics, 2021, 592, ⟨10.1016/j.ijpharm.2020.120041⟩ Article dans une revue hal-03290554v1
	Comprehensive and quantitative stability study of ascorbic acid using capillary zone electrophoresis with ultraviolet detection and high-resolution tandem mass spectrometry Pauline Legrand , Rabah Gahoual , Raphael Benattar , Balthazar Toussaint , Caroline Roques Journal of Separation Science, 2020, 43 (14), pp.2925-2935. ⟨10.1002/jssc.202000389⟩ Article dans une revue hal-03289975v1
	Thermosensitive hydrogels for local delivery of 5-fluorouracil as neoadjuvant or adjuvant therapy in colorectal cancer Chantal Al Sabbagh , Johanne Seguin , Elena Agapova , Dounia Kramerich , Vincent Boudy European Journal of Pharmaceutics and Biopharmaceutics, 2020, 157, pp.154-164. ⟨10.1016/j.ejpb.2020.10.011⟩ Article dans une revue hal-03290582v1
	Novel in situ gelling ophthalmic drug delivery system based on gellan gum and hydroxyethylcellulose: Innovative rheological characterization, in vitro and in vivo evidence of a sustained precorneal retention time Pierre-Louis Destruel , Ni Zeng , Johanne Seguin , Sophie Douat , Frederic Rosa International Journal of Pharmaceutics, 2020, 574, pp.118734. ⟨10.1016/j.ijpharm.2019.118734⟩ Article dans une revue hal-03290593v1
	Theranostic MRI liposomes for magnetic targeting and ultrasound triggered release of the antivascular CA4P Caroline J Thébault , Grégory Ramniceanu , Sarah Boumati , Aude Michel , Johanne Seguin Journal of Controlled Release, 2020, 322, pp.137-148. ⟨10.1016/j.jconrel.2020.03.003⟩ Article dans une revue hal-03059422v1
	Editorial: Supramolecular Nanomaterials for Engineering, Drug Delivery, and Medical Applications Elise Lepeltier , Vincent Levet , Tu Lee , Nathalie Mignet , Jianliang Shen Frontiers in Chemistry, 2020, 8, pp.626468. ⟨10.3389/fchem.2020.626468⟩ Article dans une revue hal-03050105v1
	In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics Pierre-Louis Destruel , Ni Zeng , Françoise Brignole-Baudouin , Sophie Douat , Johanne Seguin Pharmaceutics, 2020, 12 (4), pp.360. ⟨10.3390/pharmaceutics12040360⟩ Article dans une revue hal-02798293v1
	Coating Persistent Luminescence Nanoparticles With Hydrophilic Polymers for in vivo Imaging Jianhua Liu , Lenka Kotrchová , Thomas Lécuyer , Yohann Corvis , Johanne Seguin Frontiers in Chemistry, 2020, 8, pp.584114. ⟨10.3389/fchem.2020.584114⟩ Article dans une revue hal-03084996v1
	Development of Theranostic Cationic Liposomes Designed for Image-Guided Delivery of Nucleic Acid Hai Doan Do , Christine Ménager , Aude Michel , Johanne Seguin , Tawba Korichi Pharmaceutics, 2020, 12 (9), pp.854. ⟨10.3390/pharmaceutics12090854⟩ Article dans une revue hal-03059436v1
	Advancement in nanogel formulations provides controlled drug release Shayan Ahmed , Khair Alhareth , Nathalie Mignet International Journal of Pharmaceutics, 2020, 584, pp.119435 -. ⟨10.1016/j.ijpharm.2020.119435⟩ Article dans une revue hal-03490686v1
	Kinetic and structural characterization of therapeutic albumin chemical functionalization using complementary mass spectrometry techniques Rabah Gahoual , Gérard Bolbach , Ikram Ould-Melha , Gilles Clodic , Yannis Francois Journal of Pharmaceutical and Biomedical Analysis, 2020, 185, pp.113242. ⟨10.1016/j.jpba.2020.113242⟩ Article dans une revue hal-03022806v1
	Qualitative and quantitative analysis of the uptake of lipoplexes by villous placenta explants Khair Alhareth , Lucie Valero , Khaled Elhady Mohamed , Louise Fliedel , Caroline Roques International Journal of Pharmaceutics, 2019, 567, pp.118479. ⟨10.1016/j.ijpharm.2019.118479⟩ Article dans une revue hal-03017996v1
	Mucoadhesive thermosensitive hydrogel for the intra-tumoral delivery of immunomodulatory agents, in vivo evidence of adhesion by means of non-invasive imaging techniques Katia Lemdani , Johanne Seguin , Christelle Lesieur , Chantal Al Sabbagh , Bich-Thuy Doan International Journal of Pharmaceutics, 2019, 567, pp.118421. ⟨10.1016/j.ijpharm.2019.06.012⟩ Article dans une revue hal-02325457v1
	Conception of nanosized hybrid liposome/poloxamer particles to thicken the interior core of liposomes and delay hydrophilic drug delivery Shayan Ahmed , Yohann Corvis , Rabah Gahoual , Arlen Euan , Rene Lai-Kuen International Journal of Pharmaceutics, 2019, 567, ⟨10.1016/j.ijpharm.2019.118488⟩ Article dans une revue hal-03290600v1
	Degradation of ZnGa2O4:Cr3+ luminescent nanoparticles in lysosomal-like medium Cyrille Richard , Florence Gazeau , Nathalie Mignet , Daniel Scherman , Damien Alloyeau Nanoscale, 2019, ⟨10.1039/C9NR06867H⟩ Article dans une revue hal-02415118v1
	State of the Art of Pharmaceutical Solid Forms: from Crystal Property Issues to Nanocrystals Formulation Brice Martin Couillaud , Philippe Espeau , Nathalie Mignet , Yohann Corvis ChemMedChem, 2019, 14 (1), pp.8-23. ⟨10.1002/cmdc.201800612⟩ Article dans une revue hal-02123129v1
	AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine François Lux , Vu Long Tran , Eloise Thomas , Sandrine Dufort , Fabien Rossetti British Journal of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩ Article dans une revue hal-01935540v1
	Advances on non-invasive physically triggered nucleic acid delivery from nanocarriers Hai Doan Do , Brice Martin Couillaud , Bich-Thuy Do , Yohann Corvis , Nathalie Mignet Advanced Drug Delivery Reviews, 2019, 138, pp.3-17. ⟨10.1016/j.addr.2018.10.006⟩ Article dans une revue hal-02123133v1
	Europium labeled lactosylated albumin as a model workflow for the development of biotherapeutics Hugo Salmon , Rabah Gahoual , Pascal Houzé , Tayssir Ibrahim , Michel Bessodes Nanomedicine: Nanotechnology, Biology and Medicine, 2019, 18, pp.21-30. ⟨10.1016/j.nano.2019.02.011⟩ Article dans une revue hal-02123126v1
	Imaging and therapeutic applications of persistent luminescence nanomaterials Jianhua Liu , Thomas Lécuyer , Johanne Seguin , Nathalie Mignet , Daniel Scherman Advanced Drug Delivery Reviews, 2019, 138, pp.193-210. ⟨10.1016/j.addr.2018.10.015⟩ Article dans une revue hal-02123130v1
	Liposomes as Gene Delivery Vectors for Human Placental Cells Lucie Valero , Khair Alhareth , Jenifer Espinoza Romero , Warren Viricel , Jeanne Leblond Molecules, 2018, 23 (5), pp.1085. ⟨10.3390/molecules23051085⟩ Article dans une revue hal-02123142v1
	One-pot direct synthesis for multifunctional ultrasmall hybrid silica nanoparticles Vu-Long Tran , Vivek Thakare , Fabien Rossetti , Anne Baudouin , Grégory Ramniceanu Journal of materials chemistry‎ B, 2018, 6 (29), pp.4821 - 4834. ⟨10.1039/c8tb00195b⟩ Article dans une revue hal-01861704v1
	Assessment of the targeting specificity of a fluorescent albumin conceived as a preclinical agent of the liver function K. Lemdani , H. Salmon , R. Gahoual , M. Bessodes , D. Scherman Nanoscale, 2018, 10 (45), pp.21151-21160. ⟨10.1039/c8nr04163f⟩ Article dans une revue hal-02123131v1
	Novel Perfluorinated Triblock Amphiphilic Copolymers for Lipid-Shelled Microbubble Stabilization Yohann Corvis , Simona Manta , Caroline Thébault , Olivier Couture , Hélène Dhotel Langmuir, 2018, 34 (33), pp.9744-9753. ⟨10.1021/acs.langmuir.8b01668⟩ Article dans une revue hal-02123140v1
	Liposomes as Gene Delivery Vectors for Human Placental Cells Lucie Valero , Khair Alhareth , Jenifer Espinoza Romero , Warren Viricel , Jeanne Leblond Molecules, 2018, 23 (5), pp.1085. ⟨10.3390/molecules23051085⟩ Article dans une revue hal-04119751v1
	In vitro distinction between proinflammatory and antiinflammatory macrophages with gadolinium-liposomes and ultrasmall superparamagnetic iron oxide particles at 3.0T Wassef Khaled , Joao Piraquive , Benjamin Leporq , Jing Hong Wan , Simon Lambert Journal of Magnetic Resonance Imaging, 2018, ⟨10.1002/jmri.26331⟩ Article dans une revue hal-01917473v1
	Use of mouse model in pharmacokinetic studies of poorly water soluble drugs: Application to fenofibrate Badr Bahloul , Fathi Safta , Mohamed Ali Lassoued , Hélène Dhotel , Johanne Seguin Journal of Drug Delivery Science and Technology, 2018, 43, pp.149 - 153. ⟨10.1016/j.jddst.2017.10.006⟩ Article dans une revue hal-03078844v1
	Local immunomodulation combined to radiofrequency ablation results in a complete cure of local and distant colorectal carcinoma Katia Lemdani , Nathalie Mignet , Vincent Boudy , Johanne Seguin , Edward Oujagir OncoImmunology, 2018, 8 (3), pp.1550342. ⟨10.1080/2162402X.2018.1550342⟩ Article dans une revue hal-02123122v1
	Nanomedicine as a potential approach to empower the new strategies for the treatment of preeclampsia Lucie Valero , Khair Alhareth , Sophie Gil , Edouard Lecarpentier , Vassilis Tsatsaris Drug Discovery Today Biosilico, 2018, 23 (5), pp.1099-1107. ⟨10.1016/j.drudis.2018.01.048⟩ Article dans une revue hal-02123145v1
	The enzyme-like catalytic activity of cerium oxide nanoparticles and its dependency on Ce 3+ surface area concentration V. Baldim , F. Bedioui , Nathalie Mignet , I. Margaill , Jean-Francois Berret Nanoscale, 2018, 10 (15), pp.6971-6980. ⟨10.1039/C8NR00325D⟩ Article dans une revue hal-02342481v1
	In Vivo Evaluation of Magnetic Targeting in Mice Colon Tumors with Ultra-Magnetic Liposomes Monitored by MRI Caroline J Thébault , Grégory Ramniceanu , Aude Michel , Claire Beauvineau , Christian Girard Molecular Imaging and Biology, 2018, 21 (2), pp.269-278. ⟨10.1007/s11307-018-1238-3⟩ Article dans une revue hal-01873316v1
	Liposomes as Gene Delivery Vectors for Human Placental Cells Lucie Valero , Khair Alhareth , Jenifer Espinoza Romero , Warren Viricel , Jeanne Leblond Molecules, 2018, 23 (5), pp.1085. ⟨10.3390/molecules23051085⟩ Article dans une revue hal-03806287v1
	Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver Simona Manta , Gilles Renault , Anthony Delalande , Olivier Couture , Isabelle Lagoutte Journal of Controlled Release, 2017, 262, pp.170 - 181. ⟨10.1016/j.jconrel.2017.07.015⟩ Article dans une revue hal-01656574v1
	Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery Ni Zeng , Johanne Seguin , Pierre-Louis Destruel , Gilles Dumortier , Marc Maury International Journal of Pharmaceutics, 2017, 534 (1-2), pp.128-135. ⟨10.1016/j.ijpharm.2017.09.073⟩ Article dans une revue hal-02123148v1
	Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo human models: the dually perfused placenta and the suspended villous explants Lucie Valero , Khair Alhareth , Sophie Gil , Christelle Simasotchi , Caroline Roques International Journal of Pharmaceutics, 2017, 532 (2), pp.729-737. ⟨10.1016/j.ijpharm.2017.07.076⟩ Article dans une revue hal-04119770v1
	Photo-stimulation of persistent luminescence nanoparticles enhances cancer cells death Gonzalo Ramirez-Garcia , Minerva Martinez-Alfaro , Fanny d'Orlye , Fethi Bedioui , Nathalie Mignet International Journal of Pharmaceutics, 2017, 532 (2), pp.696-703. ⟨10.1016/j.ijpharm.2017.07.009⟩ Article dans une revue hal-03290589v1
	Electrokinetic Hummel-Dreyer characterization of nanoparticle-plasma protein corona: The non-specific interactions between PEG-modified persistent luminescence nanoparticles and albumin Gonzalo Ramirez-Garcia , Fanny d'Orlye , Silvia Gutierrez-Granados , Minerva Martinez-Alfaro , Nathalie Mignet Colloids and Surfaces B: Biointerfaces, 2017, 159, pp.437-444. ⟨10.1016/j.colsurfb.2017.08.012⟩ Article dans une revue hal-03290592v1
	Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery Anthony Delalande , Colette Bastié , Lucie Pigeon , Simona Manta , Matthias Lebertre Bioscience Reports, 2017, 37 (6), pp.BSR20160619. ⟨10.1042/BSR20160619⟩ Article dans une revue hal-02123147v1
	Photo-stimulation of persistent luminescence nanoparticles enhances cancer cells death Gonzalo Ramírez-García , Minerva Martínez-Alfaro , Fanny D’orlyé , Fethi Bedioui , Nathalie Mignet International Journal of Pharmaceutics, 2017, 532 (2), pp.696-703. ⟨10.1016/j.ijpharm.2017.07.009⟩ Article dans une revue hal-03897145v1
	EVALUATION OF ANTIVASCULAR COMBRETASTATIN A4P EFFICACY BY USING SUPERSONIC SHEAR IMAGING TECHNIQUE OF ECTOPIC COLON CARCINOMA CT26 Johanne Seguin , Nathalie Mignet , Heldmuth Latorre Ossa , Mickaël Tanter , Jean-Luc Gennisson Ultrasound Med Biol, 2017, 43 (10), pp.2352-2361 Article dans une revue hal-03191947v1
	Long-term toxicological effects of persistent luminescence nanoparticles after intravenous injection in mice Gonzalo Ramírez-García , Silvia Gutiérrez-Granados , Marco Gallegos-Corona , Lourdes Palma-Tirado , Fanny D’orlyé International Journal of Pharmaceutics, 2017, 532 (2), pp.686-695. ⟨10.1016/j.ijpharm.2017.07.015⟩ Article dans une revue hal-03897149v1
	Electrokinetic Hummel-Dreyer characterization of nanoparticle-plasma protein corona: The non-specific interactions between PEG-modified persistent luminescence nanoparticles and albumin Gonzalo Ramírez-García , Fanny D’orlyé , Silvia Gutiérrez-Granados , Minerva Martínez-Alfaro , Nathalie Mignet Colloids and Surfaces B: Biointerfaces, 2017, 159, pp.437-444. ⟨10.1016/j.colsurfb.2017.08.012⟩ Article dans une revue hal-03897152v1
	Long-term toxicological effects of persistent luminescence nanoparticles after intravenous injection in mice Gonzalo Ramirez-Garcia , Silvia Gutierrez-Granados , Marco A. Gallegos-Corona , Lourdes Palma-Tirado , Fanny d'Orlye International Journal of Pharmaceutics, 2017, 532 (2), pp.686-695. ⟨10.1016/j.ijpharm.2017.07.015⟩ Article dans une revue hal-03290595v1
	Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo human models: the dually perfused placenta and the suspended villous explants Lucie Valero , Khair Alhareth , Sophie Gil , Christelle Simasotchi , Caroline Roques International Journal of Pharmaceutics, 2017, 532 (2), pp.729-737. ⟨10.1016/j.ijpharm.2017.07.076⟩ Article dans une revue hal-02319716v1
	Evaluation of Antivascular Combretastatin A4 P Efficacy Using Supersonic Shear Imaging Technique of Ectopic Colon Carcinoma CT26 Johanne Seguin , Nathalie Mignet , Heldmuth Latorre Ossa , Mickaël Tanter , Jean-Luc Gennisson Ultrasound in Medicine & Biology, 2017, 43 (10), pp.2352-2361. ⟨10.1016/j.ultrasmedbio.2017.05.013⟩ Article dans une revue hal-04089186v1
	Characterization of Positively Charged Lipid Shell Microbubbles with Tunable Resistive Pulse Sensing (TRPS) Method: A Technical Note Simona Manta , Anthony Delalande , Michel Bessodes , Michel Francis Bureau , Daniel Scherman Ultrasound in Medicine & Biology, 2016, 42 (2), pp.624 - 630. ⟨10.1016/j.ultrasmedbio.2015.10.010⟩ Article dans une revue hal-01407496v1
	Metabolism of Flavone-8-acetic Acid in Mice Minh Hien Pham , Nicolas Auzeil , Anne Regazzetti , Daniel Scherman , Johanne Seguin Anticancer Research, 2016, 36 (8), pp.3889-3898 Article dans une revue hal-03290548v1
	Chemically engineered persistent luminescence nanoprobes for bioimaging Thomas Lécuyer , Eliott Teston , Gonzalo Ramirez-Garcia , Thomas Maldiney , Bruno Viana Theranostics, 2016, 6 (13), pp.2488-2523. ⟨10.7150/thno.16589⟩ Article dans une revue hal-03828191v1
	Delayed hepatic uptake of multi-phosphonic acid poly(ethylene glycol) coated iron oxide measured by real-time magnetic resonance imaging G. Ramniceanu , B.-T. Doan , C. Vezignol , A. Graillot , C. Loubat RSC Advances, 2016, 6 (68), pp.63788-63800. ⟨10.1039/C6RA09896G⟩ Article dans une revue hal-02342501v1
	Functionalization and characterization of persistent luminescence nanoparticles by dynamic light scattering, laser Doppler and capillary electrophoresis Gonzalo Ramírez-García , Fanny d'Orlyé , Silvia Gutiérrez-Granados , Minerva Martínez-Alfaro , Nathalie Mignet Colloids and Surfaces B: Biointerfaces, 2015, 136, pp.272-281. ⟨10.1016/j.colsurfb.2015.09.022⟩ Article dans une revue hal-03897103v1
	Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans-epithelial permeability evaluations using TR146 human buccal epithelial cell line Ni Zeng , Nathalie Mignet , Gilles Dumortier , Elodie Olivier , Johanne Seguin International Journal of Pharmaceutics, 2015, 495 (2), pp.1028-1037. ⟨10.1016/j.ijpharm.2015.09.045⟩ Article dans une revue hal-03290547v1
	Functionalization and characterization of persistent luminescence nanoparticles by dynamic light scattering, laser Doppler and capillary electrophoresis Gonzalo Ramirez-Garcia , Fanny d'Orlye , Silvia Gutierrez-Granados , Minerva Martinez-Alfaro , Nathalie Mignet Colloids and Surfaces B: Biointerfaces, 2015, 136, pp.272-281. ⟨10.1016/j.colsurfb.2015.09.022⟩ Article dans une revue hal-03290598v1
	Self-emulsifying drug delivery system developed by the HLB-RSM approach: Characterization by transmission electron microscopy and pharmacokinetic study Johanne Seguin , Helene Dhotel , Nathalie Mignet , Badr Bahloul , Mohamed Ali Lassoued International Journal of Pharmaceutics, 2015, 487 (1-2), pp.56-63. ⟨10.1016/j.ijpharm.2015.04.018⟩ Article dans une revue hal-03290584v1
	Preparation and Evaluation of Multiple Nanoemulsions Containing Gadolinium (III) Chelate as a Potential Magnetic Resonance Imaging (MRI) Contrast Agent Estelle Sigward , Yohann Corvis , Bich-Thuy Doan , Kadri Kindsiko , Johanne Seguin Pharmaceutical Research, 2015, 32 (9), pp.2983-2994. ⟨10.1007/s11095-015-1680-8⟩ Article dans une revue hal-03290599v1
	Fine tuning of mixed ionic and hydrogen bond interactions for plasmid delivery using lipoplexes Johanne Seguin , Helene Dhotel , Rene Kai-Luen , Michel Bessodes , Nathalie Mignet European Journal of Pharmaceutics and Biopharmaceutics, 2015, 90, pp.63-69. ⟨10.1016/j.ejpb.2014.11.001⟩ Article dans une revue hal-03290551v1
	NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer. S Mahindhoratep , H Ait Bouda , Nelly El Shafey , D Scherman , A Kichler BBA - Biochimica et Biophysica Acta, 2014, 1840 (11), pp.3257-3263 Article dans une revue hal-01179311v1
	Quantification of Nitric Oxide Produced By Breast Cancer Cells Stimulated By Persistent Luminescent Nanoparticles: A Study of Nanotoxicity Mechanism Gonzalo Ramírez García , Silvia Gutierrez Granados , Minerva Martinez Alfaro , Anne Varenne , Fanny Dxorlye ECS Meeting Abstracts, 2014, MA2014-02 (22), pp.1330-1330. ⟨10.1149/MA2014-02/22/1330⟩ Article dans une revue hal-03828257v1
	NF-kappa B related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer S. Mahindhoratep , H. Ait Bouda , Nelly El Shafey , D. Scherman , A. Kichler Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (11), pp.3257-3263. ⟨10.1016/j.bbagen.2014.06.013⟩ Article dans une revue hal-03289973v1
	Influence of additives on a thermosensitive hydrogel for buccal delivery of salbutamol: Relation between micellization, gelation, mechanic and release properties Ni Zeng , Gilles Dumortier , Marc Maury , Nathalie Mignet , Vincent Boudy International Journal of Pharmaceutics, 2014, 467 (1-2), pp.70-83. ⟨10.1016/j.ijpharm.2014.03.055⟩ Article dans une revue hal-03290560v1
	Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions Estelle Sigward , Nathalie Mignet , Patrice Rat , Melody Dutot , Saleh Muhamed International Journal of Nanomedicine, 2013, 8, pp.611 - 625. ⟨10.2147/IJN.S35661⟩ Article dans une revue hal-01583935v1
	Investigating relationship between transfection and permeabilization by the electric field and/or the Pluronic® L64 in vitro and in vivo. Michel Francis Bureau , Luc Wasungu , Lauriane Jugé , Daniel Scherman , Marie-Pierre Rols The Journal of Gene Medicine, 2012, 14 (3), pp.204-15. ⟨10.1002/jgm.2610⟩ Article dans une revue inserm-00679701v1
	Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges Anthony Delalande , Michiel Postema , Nathalie Mignet , Patrick Midoux , Chantal Pichon Therapeutic Delivery, 2012, 3 (10), pp.1199-1215. ⟨10.4155/TDE.12.100⟩ Article dans une revue hal-03193228v1
	Vascular density and endothelial cell expression of integrin alpha v beta 3 and E-selectin in murine tumours. Johanne Seguin , Céline Nicolazzi , Nathalie Mignet , Daniel Scherman , Guy G. Chabot Tumor Biology, 2012, 33 (5), pp.1709-17. ⟨10.1007/s13277-012-0428-x⟩ Article dans une revue inserm-00709732v1
	Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges. Anthony Delalande , Michiel Postema , Nathalie Mignet , Patrick Midoux , Chantal Pichon Ther Deliv, 2012, 3 (10), pp.1199-1215 Article dans une revue hal-00817350v1
	Protonation of lipids impacts the supramolecular and biological properties of their self-assembly. Marie Breton , Jean-François Berret , Claudie Bourgaux , Teresa Kral , Martin Hof Langmuir, 2011, 27 (20), pp.12336-45. ⟨10.1021/la202439s⟩ Article dans une revue hal-00720543v1
	Lipothioureas as Lipids for Gene Transfection: A Review Marie Breton , Jeanne Leblond , Isabelle Tranchant , Daniel Scherman , Michel Bessodes Pharmaceuticals, 2011, 4 (10), pp.1381-1399. ⟨10.3390/ph4101381⟩ Article dans une revue hal-02512516v1
	Synthesis and Application of Lactosylated, 99m Tc Chelating Albumin for Measurement of Liver Function Philippe Chaumet-Riffaud , Ivan Martinez-Duncker , Anne-Laure Marty , Cyrille Richard , Alain Prigent Bioconjugate Chemistry, 2010, 21 (4), pp.589-596. ⟨10.1021/bc900275f⟩ Article dans une revue hal-03827687v1
	Interactions between sub-10-nm iron and cerium oxide nanoparticles and 3T3 fibroblasts: the role of the coating and aggregation state Malak Safi , Hiba Sarrouj , Olivier Sandre , Nathalie Mignet , Jean-François Berret Nanotechnology, 2010, 21, pp.145103. ⟨10.1088/0957-4484/21/14/145103⟩ Article dans une revue hal-00533474v1
	Iminothiol/thiourea tautomeric equilibrium in thiourea lipids impacts DNA compaction by inducing a cationic nucleation for complex assembly Marie Breton , Michel Bessodes , Serge Bouaziz , Jean Herscovici , Daniel Scherman Biophysical Chemistry, 2009, 145 (1), pp.7-16. ⟨10.1016/j.bpc.2009.08.003⟩ Article dans une revue hal-02122492v1
	Iminothiol/thiourea tautomeric equilibrium in thiourea lipids impacts DNA compaction by inducing a cationic nucleation for complex assembly Marie Breton , Michel Bessodes , Serge Bouaziz , Jean Herscovici , Daniel Scherman Biophysical Chemistry, 2009, 145 (1), pp.7. ⟨10.1016/j.bpc.2009.08.003⟩ Article dans une revue hal-00579023v1
	Functionalization of single- and multi-walled carbon nanotubes with cationic amphiphiles for plasmid DNA complexation and transfection Cyrille Richard , Nathalie Mignet , Céline Largeau , Virginie Escriou , Michel Bessodes Nano Research, 2009, 2 (8), pp.638-647. ⟨10.1007/s12274-009-9066-z⟩ Article dans une revue hal-03827709v1
	Comparative gene transfer between cationic and thiourea lipoplexes Marie Breton , Jeanne Leblond , Johanne Seguin , Patrick Midoux , Daniel Scherman The Journal of Gene Medicine, 2009, 12 (1), pp.45-54. ⟨10.1002/jgm.1417⟩ Article dans une revue hal-02512540v1
	Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging C. Richard , P. Chaumet-Riffaud , A. Belland , A. Parat , C. Contino-Pepin International Journal of Pharmaceutics, 2009, 379 (2), pp.301-308. ⟨10.1016/j.ijpharm.2009.05.045⟩ Article dans une revue hal-03827705v1
	Lipopolythiourea Transfecting Agents: Lysine Thiourea Derivatives Jeanne Leblond , Nathalie Mignet , Celine Largeau , Johanne Seguin , Daniel Scherman Bioconjugate Chemistry, 2007, ⟨10.1021/bc7001924⟩ Article dans une revue hal-02512550v1
	Design, Synthesis, and Evaluation of Enhanced DNA Binding New Lipopolythioureas Jeanne Leblond , Nathalie Mignet , Lucie Leseurre , Celine Largeau , Michel Bessodes Bioconjugate Chemistry, inPress, ⟨10.1021/bc060110g⟩ Article dans une revue hal-02512562v1
	Liposome biodistribution by time resolved fluorimetry of lipophilic europium complexes Nathalie Mignet , Le Masne de Chermont Quentin , Randrianarivelo Tatiana , Seguin Johanne , Richard Cyrille European Biophysics Journal, 2006, 35 (2), pp.155-161 Article dans une revue inserm-00162498v1
	Design, synthesis, and evaluation of enhanced DNA binding new lipopolythioureas. Jeanne Leblond , Nathalie Mignet , Lucie Leseurre , Céline Largeau , Michel Bessodes Bioconjugate Chemistry, 2006, 17 (5), pp.1200-8. ⟨10.1021/bc060110g⟩ Article dans une revue inserm-00165275v1

	Sparse non-negative matrix factorization for preclinical bioluminescent imaging Erwan Dereure , Christophe Kervazo , Seguin Johanne , Anikitos Garofalakis , Elsa Angelini IEEE International Symposium on Biomedical Imaging (ISBI), Apr 2023, Cartagena, Colombia Communication dans un congrès hal-04061864v1
	Factorisation Non-Négative de Matrice pour séparation de sources en Imagerie par Bioluminescence préclinique Erwan Dereure , Elsa Angelini , Anikitos Garofalakis , Johanne Seguin , Nathalie Mignet GRETSI '22 : XXVIIIème Colloque Francophone de Traitement du Signal et des Images, Sep 2022, Nancy, France Communication dans un congrès hal-04195670v2
	Multimodal RM and Optic Imaging using ultramagnetic liposomes to monitor a cancer therapy Caroline J Thébault , Grégory Ramniceanu , Johanne Seguin , Aude Michel , Claire Beauvineau Journées RITS 2015, Mar 2015, Dourdan, France. p16-17 Section nanomédecine Communication dans un congrès inserm-01143980v1
	Phosphonate PEG Copolymers to control the USPIO stealthiness Gregory Ramniceanu , Bich-Thuy Doan , Camille Vezignol , Alain Graillot , Quentin Crouzet Journées RITS 2015, Mar 2015, Dourdan, France. p20-21 Communication dans un congrès inserm-01145542v1
	Positively charged microbubbles to target nucleic acid delivery with ultrasound Simona Manta , Anthony Delalande , Gilles Renault , Michel Francis Bureau , Matthias Lebertre Journées RITS 2015, Mar 2015, Dourdan, France Communication dans un congrès inserm-01154976v1
	Distinction between pro and anti-inflammatory macrophages using MRI relaxometry and quantitative susceptibility mapping Wassef Khaled , Benjamin Leporq , J.H Wan , Philippe Garteiser , Simon A. Lambert 23th International Society of Magnetic Resonance in Medicine annual meeting, May 2015, Toronto, Canada Communication dans un congrès hal-01918412v1
	Grading cancer from liver histology images using inter and intra region spatial relations Mickaël Garnier , Maya Alsheh Ali , Johanne Seguin , Nathalie Mignet , Thomas Hurtut International Conference on Image Analysis and Recognition, Oct 2014, Portugal. pp.247-254 Communication dans un congrès hal-01063797v1
	Comparison of the Spatial Organization in Colorectal Tumors using Second-Order Statistics and Functional ANOVA Maya Alsheh Ali , Johanne Seguin , Aurélie Fisher , Nathalie Mignet , Laurent Wendling Image and Signal Processing and Analysis (ISPA), 2013 8th International Symposium on, 2013, Italy. pp.257 - 261, ⟨10.1109/ISPA.2013.6703749⟩ Communication dans un congrès hal-00992369v1
	Comparison of the Spatial Organization in Colorectal Tumors using Second-Order Statistics and Functional ANOVA M. Alsheh Ali , J. Seguin , A. Fischer , Nathalie Mignet , L. Wendling Image and Signal Processing and Analysis (ISPA), 2013 8th International Symposium on, 2013, Trieste, Italy. pp.257-261, ⟨10.1109/ISPA.2013.6703749⟩ Communication dans un congrès hal-01020634v1

	Microbubbles for Nucleic Acid Delivery in Liver Using Mild Sonoporation Nathalie Mignet , Corinne Marie , Anthony Delalande , Simona Manta , Johanne Seguin Nanotechnology for Nucleic Acid Delivery, pp.377-387, 2019, Methods in Molecular Biology, ⟨10.1007/978-1-4939-9092-4_25⟩ Chapitre d'ouvrage hal-02123117v1
	Lipids for Nucleic Acid Delivery: Cationic or Neutral Lipoplexes, Synthesis, and Particle Formation Michel Bessodes , Helene Dhotel , Nathalie Mignet Manfred Ogris, Haider Sami. Nanotechnology for Nucleic Acid Delivery : Methods and Protocols, 1943, Springer New York, pp.123-139, 2019, Methods in Molecular Biology, 978-1-4939-9091-7. ⟨10.1007/978-1-4939-9092-4_8⟩ Chapitre d'ouvrage hal-02123120v1
	INCREASED SENSITIVITY FOR MEDICAL IMAGING USING NON-IONIZING NANOMEDICINE AS CONTRAST AGENTS Cyrille Richard , Bich-Thuy Doan , Nathalie Mignet Nanotheranostics for Personalized Medicine, WORLD SCIENTIFIC, pp.7-44, 2016, ⟨10.1142/9789814713535_0002⟩ Chapitre d'ouvrage hal-03828223v1

Nathalie Mignet

Présentation

Publications

Zwitterionic Functionalization of Persistent Luminescence Nanoparticles: Physicochemical Characterizations and In Vivo Biodistribution in Mice

Fate and biological impact of persistent luminescence nanoparticles after injection in mice: a one-year follow-up

Co-encapsulation of flavonoids with anti–cancer drugs : A challenge ahead

New Preservative-Free Formulation for the Enhanced Ocular Bioavailability of Prostaglandin Analogues in Glaucoma

In vivo ultrasound modulated optical tomography with a persistent spectral hole burning filter

Persistent luminescence nanoparticles functionalized by polymers bearing phosphonic acid anchors: synthesis, characterization, and in vivo behaviour

Influence of Liposomes’ and Lipoplexes’ Physicochemical Characteristics on Their Uptake Rate and Mechanisms by the Placenta

Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy

Placental Models for Evaluation of Nanocarriers as Drug Delivery Systems for Pregnancy Associated Disorders

How Could Nanomedicine Improve the Safety of Contrast Agents for MRI during Pregnancy?

Combination of tumor cell anti-adhesion and anti-tumor effect to prevent recurrence after cytoreductive surgery in a mice model

Antioxidant activity and toxicity study of cerium oxide nanoparticles stabilized with innovative functional copolymers

Co-Encapsulation of Fisetin and Cisplatin into Liposomes for Glioma Therapy: From Formulation to Cell Evaluation

Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses

Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged

Persistent luminescence nanoparticles functionalized by polymers bearing phosphonic acid anchors: synthesis, characterization, and in vivo behaviour

Electrokinetic elucidation of the interactions between persistent luminescent nanoprobes and the binary apolipoprotein-E/albumin protein system

Drug delivery systems to prevent peritoneal metastasis after surgery of digestives or ovarian carcinoma: A review

Comprehensive and quantitative stability study of ascorbic acid using capillary zone electrophoresis with ultraviolet detection and high-resolution tandem mass spectrometry

Thermosensitive hydrogels for local delivery of 5-fluorouracil as neoadjuvant or adjuvant therapy in colorectal cancer

Novel in situ gelling ophthalmic drug delivery system based on gellan gum and hydroxyethylcellulose: Innovative rheological characterization, in vitro and in vivo evidence of a sustained precorneal retention time

Theranostic MRI liposomes for magnetic targeting and ultrasound triggered release of the antivascular CA4P

Editorial: Supramolecular Nanomaterials for Engineering, Drug Delivery, and Medical Applications

In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics

Coating Persistent Luminescence Nanoparticles With Hydrophilic Polymers for in vivo Imaging

Development of Theranostic Cationic Liposomes Designed for Image-Guided Delivery of Nucleic Acid

Advancement in nanogel formulations provides controlled drug release

Kinetic and structural characterization of therapeutic albumin chemical functionalization using complementary mass spectrometry techniques

Qualitative and quantitative analysis of the uptake of lipoplexes by villous placenta explants

Mucoadhesive thermosensitive hydrogel for the intra-tumoral delivery of immunomodulatory agents, in vivo evidence of adhesion by means of non-invasive imaging techniques

Conception of nanosized hybrid liposome/poloxamer particles to thicken the interior core of liposomes and delay hydrophilic drug delivery

Degradation of ZnGa2O4:Cr3+ luminescent nanoparticles in lysosomal-like medium

State of the Art of Pharmaceutical Solid Forms: from Crystal Property Issues to Nanocrystals Formulation

AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Advances on non-invasive physically triggered nucleic acid delivery from nanocarriers

Europium labeled lactosylated albumin as a model workflow for the development of biotherapeutics

Imaging and therapeutic applications of persistent luminescence nanomaterials

Liposomes as Gene Delivery Vectors for Human Placental Cells

One-pot direct synthesis for multifunctional ultrasmall hybrid silica nanoparticles

Assessment of the targeting specificity of a fluorescent albumin conceived as a preclinical agent of the liver function

Novel Perfluorinated Triblock Amphiphilic Copolymers for Lipid-Shelled Microbubble Stabilization

Liposomes as Gene Delivery Vectors for Human Placental Cells

In vitro distinction between proinflammatory and antiinflammatory macrophages with gadolinium-liposomes and ultrasmall superparamagnetic iron oxide particles at 3.0T

Use of mouse model in pharmacokinetic studies of poorly water soluble drugs: Application to fenofibrate

Local immunomodulation combined to radiofrequency ablation results in a complete cure of local and distant colorectal carcinoma

Nanomedicine as a potential approach to empower the new strategies for the treatment of preeclampsia

The enzyme-like catalytic activity of cerium oxide nanoparticles and its dependency on Ce 3+ surface area concentration

In Vivo Evaluation of Magnetic Targeting in Mice Colon Tumors with Ultra-Magnetic Liposomes Monitored by MRI

Liposomes as Gene Delivery Vectors for Human Placental Cells

Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver

Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery

Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo human models: the dually perfused placenta and the suspended villous explants

Photo-stimulation of persistent luminescence nanoparticles enhances cancer cells death

Electrokinetic Hummel-Dreyer characterization of nanoparticle-plasma protein corona: The non-specific interactions between PEG-modified persistent luminescence nanoparticles and albumin

Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery

Photo-stimulation of persistent luminescence nanoparticles enhances cancer cells death

EVALUATION OF ANTIVASCULAR COMBRETASTATIN A4P EFFICACY BY USING SUPERSONIC SHEAR IMAGING TECHNIQUE OF ECTOPIC COLON CARCINOMA CT26

Long-term toxicological effects of persistent luminescence nanoparticles after intravenous injection in mice

Electrokinetic Hummel-Dreyer characterization of nanoparticle-plasma protein corona: The non-specific interactions between PEG-modified persistent luminescence nanoparticles and albumin

Long-term toxicological effects of persistent luminescence nanoparticles after intravenous injection in mice

Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo human models: the dually perfused placenta and the suspended villous explants

Evaluation of Antivascular Combretastatin A4 P Efficacy Using Supersonic Shear Imaging Technique of Ectopic Colon Carcinoma CT26

Characterization of Positively Charged Lipid Shell Microbubbles with Tunable Resistive Pulse Sensing (TRPS) Method: A Technical Note

Metabolism of Flavone-8-acetic Acid in Mice

Chemically engineered persistent luminescence nanoprobes for bioimaging

Delayed hepatic uptake of multi-phosphonic acid poly(ethylene glycol) coated iron oxide measured by real-time magnetic resonance imaging

Functionalization and characterization of persistent luminescence nanoparticles by dynamic light scattering, laser Doppler and capillary electrophoresis

Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans-epithelial permeability evaluations using TR146 human buccal epithelial cell line

Functionalization and characterization of persistent luminescence nanoparticles by dynamic light scattering, laser Doppler and capillary electrophoresis

Self-emulsifying drug delivery system developed by the HLB-RSM approach: Characterization by transmission electron microscopy and pharmacokinetic study

Preparation and Evaluation of Multiple Nanoemulsions Containing Gadolinium (III) Chelate as a Potential Magnetic Resonance Imaging (MRI) Contrast Agent

Fine tuning of mixed ionic and hydrogen bond interactions for plasmid delivery using lipoplexes

NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer.

Quantification of Nitric Oxide Produced By Breast Cancer Cells Stimulated By Persistent Luminescent Nanoparticles: A Study of Nanotoxicity Mechanism

NF-kappa B related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer

Influence of additives on a thermosensitive hydrogel for buccal delivery of salbutamol: Relation between micellization, gelation, mechanic and release properties

Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions