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A triazolium‐anchored self‐immolative linker enables self‐assembly‐driven siRNA binding and esterase‐induced release

Selina Hollstein , Lamiaa Ali , Maëva Coste , Julian Vogel , Nadir Bettache
Chemistry - A European Journal, 2023, 29 (8), pp.e202203311. ⟨10.1002/chem.202203311⟩
Article dans une revue hal-03854124v1
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Periodic mesoporous ionosilica nanoparticles for dual cancer therapy: Two-photon excitation siRNA gene silencing in cells and photodynamic therapy in zebrafish embryos

Braham Mezghrani , Lamiaa M.A. Ali , Nicolas Cubedo , Mireille Rossel , Peter Hesemann
International Journal of Pharmaceutics, 2023, 641, pp.123083. ⟨10.1016/j.ijpharm.2023.123083⟩
Article dans une revue hal-04121650v1
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Periodic Mesoporous Ionosilica Nanoparticles for BODIPY Delivery and Photochemical Internalization of siRNA

Braham Mezghrani , Lamiaa Ali , Sara Jakimoska , Frédérique Cunin , Peter Hesemann
ChemPlusChem, 2023, 88 (3), pp.e202300021. ⟨10.1002/cplu.202300021⟩
Article dans une revue hal-04062152v1
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Wound Dressings Based on Sodium Alginate–Polyvinyl Alcohol–Moringa oleifera Extracts

Samir Kamel , Sawsan Dacrory , Peter Hesemann , Nadir Bettache , Lamiaa M A Ali
Pharmaceutics, 2023, 15 (4), pp.1270. ⟨10.3390/pharmaceutics15041270⟩
Article dans une revue hal-04090038v1
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Structure‐Activity Relationships in Nucleic‐Acid‐Templated Vectors Based on Peptidic Dynamic Covalent Polymers

Dan-Dan Su , Lamiaa Ali , Maëva Coste , Nabila Laroui , Yannick Bessin
Chemistry - A European Journal, 2022, ⟨10.1002/chem.202202921⟩
Article dans une revue hal-03854114v1

Phytochemical profile and biological effects of essential oils from three Inula species grown in Tunisia

Nawres Gharred , Lamiaa Ali , Nadir Bettache , Alain Morere , Chantal Menut
Journal of Essential Oil Research, 2022, 34 (5), pp.405-415. ⟨10.1080/10412905.2022.2075479⟩
Article dans une revue hal-03854083v1
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Photosensitivity of Different Nanodiamond–PMO Nanoparticles in Two-Photon-Excited Photodynamic Therapy

Nicolas Bondon , Denis Durand , Kamel Hadj-Kaddour , Lamiaa M A Ali , Rabah Boukherroub
Life, 2022, This article belongs to the Special Issue Photodynamic Diagnosis and Therapy, 12 (12), pp.2044. ⟨10.3390/life12122044⟩
Article dans une revue hal-03896140v2
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A rational study of the influence of Mn(2+)-insertion in Prussian blue nanoparticles on their photothermal properties

Maëlle Cahu , Lamiaa M A Ali , Saad Sene , Jérôme Long , Franck Camerel
Journal of materials chemistry‎ B, 2021, 9 (47), pp.9670-9683. ⟨10.1039/d1tb00888a⟩
Article dans une revue hal-03414675v1
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Periodic Mesoporous Ionosilica Nanoparticles for Green Light Photodynamic Therapy and Photochemical Internalization of siRNA

Braham Mezghrani , Lamiaa M A Ali , Sébastien Richeter , Jean-Olivier Durand , Peter Hesemann
ACS Applied Materials & Interfaces, 2021, 13, pp.29325-29339. ⟨10.1021/acsami.1c05848⟩
Article dans une revue hal-03279491v1
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Cell‐selective siRNA delivery using glycosylated dynamic covalent polymers self‐assembled in situ by RNA‐templating

Nabila Laroui , Maëva Coste , Dandan Su , Lamiaa Ali , Yannick Bessin
Angewandte Chemie International Edition, 2021, 60 (11), pp.5783-5787. ⟨10.1002/anie.202014066⟩
Article dans une revue hal-03113520v1
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Vegetable oil-based hybrid microparticles as a green and biocompatible system for subcutaneous drug delivery

Koceïla Doufène , Ilaria Basile , Aurélien Lebrun , Nelly Pirot , Aurélie Escande
International Journal of Pharmaceutics, 2021, 592, pp.120070. ⟨10.1016/j.ijpharm.2020.120070⟩
Article dans une revue hal-03110144v1
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Modified Indulines: From Dyestuffs to in vivo Theranostic Agents

Zhongrui Chen , Simon Pascal , Morgane Daurat , Laure Lichon , Christophe Nguyen
ACS Applied Materials & Interfaces, 2021, ⟨10.1021/acsami.1c05933⟩
Article dans une revue hal-03269501v1

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

Nadège Hamon , Amandine Roux , Maryline Beyler , Jean-Christophe Mulatier , Chantal Andraud
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
Article dans une revue hal-02616978v1
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Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery

Matthieu Simon , Nabila Laroui , Marianne Heyraud , Guillaume Laconde , Lamiaa M A Ali
Nanomaterials, 2020, 10 (12), pp.2334. ⟨10.3390/nano10122334⟩
Article dans une revue hal-03053993v1
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Sequential delivery of synergistic drugs by silica nanocarriers for enhanced tumour treatment

Albane Birault , Simon Giret , Christophe Théron , Audrey Gallud , Afitz da Silva
Journal of materials chemistry‎ B, 2020, 8 (7), pp.1472-1480. ⟨10.1039/c9tb02225b⟩
Article dans une revue hal-03096456v1
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Cytotoxic activities of Psidium guajava and Mangifera indica plant extracts on human healthy skin fibroblasts and human hepatocellular carcinoma

Gislaine Aurelie Kemegne , Nadir Bettache , Maximilienne Ascension Nyegue , François-Xavier Etoa , Chantal Menut
Issues in Biological Sciences and Pharmaceutical Research, 2020, 8 (4), pp.58-64. ⟨10.15739/ibspr.20.007⟩
Article dans une revue hal-03114647v1

Improvement of Cell Penetrating Peptide for Efficient siRNA Targeting of Tumor Xenografts in Zebrafish Embryos

Nabila Laroui , Nicolas Cubedo , Mireille Rossel , Nadir Bettache
Advanced Therapeutics, 2020, pp.1900204. ⟨10.1002/adtp.201900204⟩
Article dans une revue hal-02460044v1
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Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Ayman El Jundi , Marie Morille , Nadir Bettache , Audrey Bethry , Jade Berthelot
Journal of Colloid and Interface Science, 2020, 580, pp.449-459. ⟨10.1016/j.jcis.2020.07.057⟩
Article dans une revue hal-03025049v1

Organosilica Nanoparticles for Gemcitabine Monophosphate Delivery in Cancer Cells

Morgane Daurat , Saher Rahmani , Roza Bouchal , Alia Akrout , Jelena Budimir
ChemNanoMat, 2019, 5 (7), pp.888-896. ⟨10.1002/cnma.201900202⟩
Article dans une revue hal-02347901v1

Front Cover: Organosilica Nanoparticles for Gemcitabine Monophosphate Delivery in Cancer Cells (ChemNanoMat 7/2019)

Morgane Daurat , Saher Rahmani , Roza Bouchal , Alia Akrout , Jelena Budimir
ChemNanoMat, 2019, 5 (7), pp.858-858. ⟨10.1002/cnma.201900267⟩
Article dans une revue hal-02989376v1
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The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

Toufic Kassouf , Romain Maxime Larive , Anne Morel , Serge Urbach , Nadir Bettache
Cancers, 2019, 11 (12), pp.1974. ⟨10.3390/cancers11121974⟩
Article dans une revue hal-02401110v1
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Porphyrin‐based bridged silsesquioxane nanoparticles for targeted two‐photon photodynamic therapy of zebrafish xenografted with human tumor

Soraya Dib , Dina Aggad , Chiara Mauriello Jimenez , Ahmed Lakrafi , Guillaume Héry
Cancer reports, 2019, 2 (5), pp.e1186. ⟨10.1002/cnr2.1186⟩
Article dans une revue hal-02355962v1
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Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes

Nabila Laroui , Maëva Coste , Laure Lichon , Yannick Bessin , Magali Gary-Bobo
International Journal of Pharmaceutics, 2019, 569, pp.118585. ⟨10.1016/j.ijpharm.2019.118585⟩
Article dans une revue hal-02322136v1

Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain-Barrier-Permeating Compounds

Olivier van Der Poorten , Baptiste Legrand , Lubomir Vezenkov , Júlia García-Pindado , Nadir Bettache
ChemBioChem, 2018, 19 (7), pp.696-705. ⟨10.1002/cbic.201700678⟩
Article dans une revue hal-03564881v1

Porous Porphyrin-Based Organosilica Nanoparticles for NIR Two-Photon Photodynamic Therapy and Gene Delivery in Zebrafish

Chiara Mauriello Jimenez , Dina Aggad , Jonas Croissant , Karen Tresfield , Danielle Laurencin
Advanced Functional Materials, 2018, 28 (21), pp.1800235. ⟨10.1002/adfm.201800235⟩
Article dans une revue hal-01973302v1

Indoloazepinone-Containing Oligomers as Cell-Penetrating (Non)Peptides: Synthesis, Structuration and Internalization

Olivier van Der Poorten , Baptiste Legrand , Lubomir Vezenkov , Jean Martinez , Nadir Bettache
Journal of Peptide Science, 2018, 22 (S2), pp.S117. ⟨10.1002/psc.2950⟩
Article dans une revue hal-03576982v1
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Biomolecular dynamic covalent polymers for DNA complexation and siRNA delivery

Camille Bouillon , Yannick Bessin , Florian Poncet , Magali Gary-Bobo , Pascal Dumy
Journal of materials chemistry‎ B, 2018, 6 (44), pp.7239-7246. ⟨10.1039/C8TB01278D⟩
Article dans une revue hal-01944488v1

Ribbon-like Foldamers for Cellular Uptake and Drug Delivery

Lubomir L. Vezenkov , Vincent Martin , Nadir Bettache , Matthieu Simon , Alexandre Messerschmitt
ChemBioChem, 2017, 18 (21), pp.2110-2114. ⟨10.1002/cbic.201700455⟩
Article dans une revue hal-01944639v1

Structure-Activity Relationships of JMV4463, a Vectorized Cathepsin D Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector

Lubomir Vezenkov , Clément Sanchez , Virginie Bellet , Vincent Martin , Marie Maynadier
ChemMedChem, 2016, 11 (3), pp.302-308. ⟨10.1002/cmdc.201500457⟩
Article dans une revue hal-02388735v1
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20-nm-sized mesoporous silica nanoparticles with porphyrin photosensitizers for in vitro photodynamic therapy

Chiara Mauriello Jimenez , Yolanda Galàn Rubio , Valentin Saunier , David Warther , Vanja Stojanovic
Journal of Sol-Gel Science and Technology, 2016, 79 (3), pp.447-456. ⟨10.1007/s10971-016-3991-6⟩
Article dans une revue hal-01569372v1
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Multivalent DNA recognition by self-assembled clusters: deciphering structural effects by fragments screening and evaluation as siRNA vectors

Eline Bartolami , Yannick Bessin , Nadir Bettache , Magali Gary-Bobo , Marcel Garcia
Organic & Biomolecular Chemistry, 2015, 13 (36), pp.9427 - 9438. ⟨10.1039/c5ob01404b⟩
Article dans une revue hal-03116768v1

Abstract 1978: The tyrosine kinase Syk plays a role in the maintenance of intercellular adhesive junctions in human breast cancer cells

Toufic Kassouf , Philippe Montcourrier , Romain Larive , Nadir Bettache , Anne Morel
Cancer Research, 2014, 74 (19S), pp.1978-1978. ⟨10.1158/1538-7445.AM2014-1978⟩
Article dans une revue hal-03575279v1
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Pro-cathepsin D interacts with the extracellular domain of the {beta} chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Mélanie Beaujouin , Christine Prébois , Danielle Derocq , Valérie Laurent-Matha , Olivier Masson
Journal of Cell Science, 2010, 123 (19), pp.3336-3346. ⟨10.1242/jcs.070938⟩
Article dans une revue inserm-00518213v1

Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling.

Romain M Larive , Laurent Baisamy , Serge Urbach , Peter Coopman , Nadir Bettache
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (3), pp.389-400. ⟨10.1016/j.bbamem.2009.11.016⟩
Article dans une revue hal-00492403v1

The gelsolin:calponin complex nucleates actin filaments with distinct morphologies.

Imen Ferjani , Abdellatif Fattoum , Nadir Bettache , Bastien Seantier , Pierre-Emmanuel Milhiet
Biochemical and Biophysical Research Communications, 2010, 392 (2), pp.118-23. ⟨10.1016/j.bbrc.2009.12.103⟩
Article dans une revue hal-00491991v1

Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.

R. M. Larive , Serge Urbach , Joël Poncet , Patrick Jouin , G. Mascré
Oncogene, 2009, 28 (24), pp.2337-47. ⟨10.1038/onc.2009.99⟩
Article dans une revue hal-00400163v1

Mechanical model of cytoskeleton structuration during cell adhesion and spreading

Bernard Maurin , Patrick Cañadas , Haimad Baudriller , Philippe Montcourrier , Nadir Bettache
Journal of Biomechanics, 2008, 41, pp.2036-2041. ⟨10.1016/j.jbiomech.2008.03.011⟩
Article dans une revue hal-00665316v1

Form-finding of complex tensegrity structures: application to cell cytoskeleton modelling

Haimad Baudriller , Bernard Maurin , Patrick Cañadas , Philippe Montcourrier , Andrea Parmeggiani
Comptes Rendus Mécanique, 2006, 334, pp.662-668. ⟨10.1016/j.crme.2006.08.004⟩
Article dans une revue hal-00559870v1

HIV-1 Tat Enters T Cells Using Coated Pits before Translocating from Acidified Endosomes and Eliciting Biological Responses

Agnès Vendeville , Fabienne Rayne , Anne Bonhoure , Nadir Bettache , Philippe Montcourrier
Molecular Biology of the Cell, 2004, 15 (5), pp.2347-2360. ⟨10.1091/mbc.e03-12-0921⟩
Article dans une revue hal-02137162v1