Skip to Main content


Social networks

  • Twitter: MOgliastro

Open access quantity

62 %

Number of documents


Mylene Ogliastro

I'm fascinated by viruses : their diversity, the mechanisms of infection, how they cross complex cellular barriers, how they evolve and switch hosts. To explore these questions, I'm focusing on insect viruses and more specifically on insect parvoviruses (so called densoviruses), looking at their interaction with their hosts at different levels, from molecules to populations.
At molecualr level, I'm particularly interested by the oral transmission of viruses, ie the more specifically by the mechanisms allowing (denso)viruses to cross the gut of their host. Viruses are wonderfull nanovehicles to explore complex cellular barriers.
At population level, I'm interested in virus ecology and evolution. We developed field sampling and viral metagenomics to understand virus diversity and viral dynamics in ecosystems and lab experimental evolution to understand how they switch host.

Journal articles33 documents

  • Jeroen Wagemans, Dominique Holtappels, Eeva Vainio, Mojgan Rabiey, Cristina Marzachì, et al.. Going Viral: Virus-Based Biological Control Agents for Plant Protection. Annual Review of Phytopathology, Annual Reviews, 2022, 60, pp.21-42. ⟨10.1146/annurev-phyto-021621-114208⟩. ⟨hal-03705054⟩
  • Caroline Deshayes, Anne-Sophie Gosselin-Grenet, Mylène Ogliastro, Bruno Lapied, Véronique Apaire-Marchais. Can Virus-like Particles Be Used as Synergistic Agent in Pest Management?. Viruses, MDPI, 2022, 14 (5), ⟨10.3390/v14050943⟩. ⟨hal-03697533⟩
  • Oumaima Moubset, Sarah François, François Maclot, Essowè Palanga, Charlotte Julian, et al.. Virion-associated nucleic acid-based metagenomics: a decade of advances in molecular characterization of plant viruses. Phytopathology, American Phytopathological Society, In press, ⟨10.1094/PHYTO-03-22-0096-RVW⟩. ⟨hal-03705057⟩
  • Thomas Labadie, Deborah Garcia, Doriane Mutuel, Mylène Ogliastro, Guillaume Cambray. Capsid Proteins Are Necessary for Replication of a Parvovirus. Journal of Virology, American Society for Microbiology, 2021, 95 (17), ⟨10.1128/JVI.00523-21⟩. ⟨hal-03335362⟩
  • Franck Dorkeld, Rejane Streiff, Carole Kerdelhué, Mylène Ogliastro. Coding-Complete Genome Sequences of an Iteradensovirus and an Alphapermutotetra-Like Virus Identified from the Pine Processionary Moth ( Thaumetopoea pityocampa ) in Portugal. Microbiology Resource Announcements, American Society for Microbiology, 2021, 10 (1), ⟨10.1128/MRA.01163-20⟩. ⟨hal-03130972⟩
  • Carole Kerdelhué, Franck Dorkeld, Rejane Streiff, Mylène Ogliastro. Coding-Complete Genome Sequence of a Partitivirus Isolated from Pine Processionary Moth Eggs. Microbiology Resource Announcements, American Society for Microbiology, 2021, 10 (8), pp.e00071-21. ⟨10.1128/MRA.00071-21⟩. ⟨hal-03180502⟩
  • Sarah François, Aymeric Antoine-Lorquin, Maximilien Kulikowski, Marie Frayssinet, Denis Filloux, et al.. Characterisation of the Viral Community Associated with the Alfalfa Weevil (Hypera postica) and Its Host Plant, Alfalfa (Medicago sativa). Viruses, MDPI, 2021, 13 (5), pp.791. ⟨10.3390/v13050791⟩. ⟨hal-03247676⟩
  • Grégory Caignard, Etienne Decroly, Maria Dimitrova, David Gilmer, Anne-Sophie Gosselin-Grenet, et al.. To something, Covid is good: SFV 2.0. Virologie, John Libbey Eurotext 2020, 24 (3), pp.133-134. ⟨10.1684/vir.2020.0846⟩. ⟨hal-02979056⟩
  • Aurélie Perrin, Anne-Sophie Gosselin-Grenet, Marie Rossignol, Carole Ginibre, Bethsabée Scheid, et al.. Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus. Scientific Reports, Nature Publishing Group, 2020, 10, ⟨10.1038/s41598-020-75765-4⟩. ⟨hal-02985676⟩
  • Laetitia Pigeyre, Malvina Schatz, Marc Ravallec, Leila Gasmi, Nicolas Negre, et al.. Interaction of a Densovirus with Glycans of the Peritrophic Matrix Mediates Oral Infection of the Lepidopteran Pest Spodoptera frugiperda. Viruses, MDPI, 2019, 11 (9), 21 p. ⟨10.3390/v11090870⟩. ⟨hal-02320559⟩
  • David Gilmer, Marie Helene Ogliastro. Report of the 17th Meeting of Plant Virology. Virologie, John Libbey Eurotext 2019, 23 (2), pp.45-49. ⟨10.1684/vir.2019.0767⟩. ⟨hal-02167528⟩
  • Sarah François, Doriane Mutuel, Alison Duncan, Leonor Rodrigues, Celya Danzelle, et al.. A New Prevalent Densovirus Discovered in Acari. Insight from Metagenomics in Viral Communities Associated with Two-Spotted Mite (Tetranychus urticae) Populations: Metagenomics in Viral Communities Associated with Two-Spotted Mite (Tetranychus urticae) Populations. Viruses, MDPI, 2019, 11 (3), pp.233. ⟨10.3390/v11030233⟩. ⟨hal-02154545⟩
  • Mine Altinli, Sebastian Lequime, Maxime Courcelle, Sarah François, Fabienne Justy, et al.. Evolution and phylogeography of Culex pipiens densovirus. Virus Evolution, Oxford University Press, 2019, 5 (2), pp.vez053. ⟨10.1093/ve/vez053⟩. ⟨hal-02965158⟩
  • Susan Cotmore, Mavis Agbandje-Mckenna, Marta Canuti, John Chiorini, Anna-Maria Eis-Hubinger, et al.. ICTV Virus Taxonomy Profile: Parvoviridae. Journal of General Virology, Microbiology Society, 2019, 100 (3), pp.367-368. ⟨10.1099/jgv.0.001212⟩. ⟨pasteur-02133263⟩
  • Lev G. Nemchinov, Sarah François, Philippe Roumagnac, Marie Helene Ogliastro, Rosemarie W. Hammond, et al.. Characterization of alfalfa virus F, a new member of the genus Marafivirus. PLoS ONE, Public Library of Science, 2018, 13 (9), ⟨10.1371/journal.pone.0203477⟩. ⟨hal-01918048⟩
  • S. Francois, Denis Filloux, Marie Frayssinet, Philippe Roumagnac, D. P. Martin, et al.. Increase in taxonomic assignment efficiency of viral reads in metagenomic studies. Virus Research, Elsevier, 2018, 244, pp.230-234. ⟨10.1016/j.virusres.2017.11.011⟩. ⟨hal-01837312⟩
  • Laila Gasmi, Agata K. Jakubowska, Juan Ferré, Marie Helene Ogliastro, Salvador Herrero. Characterization of two groups of Spodoptera exigua Hübner (Lepidoptera: Noctuidae) C-type lectins and insights into their role in defense against the densovirus JcDV. Archives of Insect Biochemistry and Physiology, Wiley, 2018, 97 (1), 12 p. ⟨10.1002/arch.21432⟩. ⟨hal-01837306⟩
  • F. Salasc, Doriane Mutuel, Solène Debaisieux, Aurélie Perrin, Thierry Dupressoir, et al.. Role of the phosphatidylinositol-3-kinase/Akt/target of rapamycin pathway during ambidensovirus infection of insect cells. Journal of General Virology, Microbiology Society, 2016, 97 (1), pp.233-245. ⟨10.1099/jgv.0.000327⟩. ⟨hal-01837297⟩
  • Véronique Apaire-Marchais, Mylène Ogliastro, Fabrice Chandre, Cédric Pennetier, Valérie Raymond, et al.. Virus and calcium: an unexpected tandem to optimize insecticide efficacy. Environmental Microbiology Reports, Wiley, 2016, 8 (2), pp.168-178. ⟨10.1111/1758-2229.12377⟩. ⟨hal-01388784⟩
  • Sarah François, Denis Filloux, Philippe Roumagnac, D. Bigot, P. Gayral, et al.. Discovery of parvovirus-related sequences in an unexpected broad range of animals. Scientific Reports, Nature Publishing Group, 2016, 6, 13 p. ⟨10.1038/srep30880⟩. ⟨hal-01511996⟩
  • Anne-Sophie Gosselin Grenet, Fanny Salasc, Sarah François, Doriane Mutuel, Thierry Dupressoir, et al.. Les densovirus : une « massive attaque » chez les arthropodes. Virologie, John Libbey Eurotext 2015, 19 (1), pp.19-31. ⟨10.1684/vir.2015.0589⟩. ⟨hal-01837284⟩
  • Sarah François, Pauline Bernardo, Denis Filloux, Philippe Roumagnac, N. Yaverkovski, et al.. A novel itera-like densovirus isolated by viral metagenomics from the sea barley Hordeum marinum. Genome Announcements, American Society for Microbiology, 2014, 2 (6), ⟨10.1128/genomeA.01196-14⟩. ⟨hal-01837275⟩
  • Muriel Vayssier Taussat, Emmanuel Albina, Christine Citti, Jean-Franҫois Cosson, Marie-Agnès Jacques, et al.. Shifting the paradigm from pathogens to pathobiome: new concepts in the light of meta-omics. Frontiers in Cellular and Infection Microbiology, Frontiers, 2014, 4, pp.n/a. ⟨10.3389/fcimb.2014.00029⟩. ⟨hal-01153583⟩
  • Fabrice Legeai, Sylvie Gimenez, Bernard Duvic, Jean-Michel Escoubas, Anne-Sophie Gosselin Grenet, et al.. Establishment and analysis of a reference transcriptome for Spodoptera frugiperda. BMC Genomics, BioMed Central, 2014, 15 (1), pp.704. ⟨10.1186/1471-2164-15-704⟩. ⟨hal-01058982⟩
  • Yuan Wang, A. S. Gosselin Grenet, Ilaria Castelli, G. Cermenati, Marc Ravallec, et al.. Densovirus Crosses the Insect Midgut by Transcytosis and Disturbs the Epithelial Barrier Function. Journal of Virology, American Society for Microbiology, 2013, 87 (22), pp.12380 - 12391. ⟨10.1128/JVI.01396-13⟩. ⟨hal-01837252⟩
  • Cécilia Multeau, Remy Froissart, Aurélie Perrin, Ilaria Castelli, Morena Casartelli, et al.. Four Amino Acids of an Insect Densovirus Capsid Determine Midgut Tropism and Virulence. Journal of Virology, American Society for Microbiology, 2012, 86 (10), pp.5937 - 5941. ⟨10.1128/JVI.06839-11⟩. ⟨hal-02646333⟩
  • Doriane Mutuel, Marc Ravallec, Béatrice Chabi, Cécilia Multeau, Jean-Michel Salmon, et al.. Pathogenesis of Junonia coenia densovirus in Spodoptera frugiperda: A route of infection that leads to hypoxia. Virology, Elsevier, 2010, 403 (2), pp.137-144. ⟨10.1016/j.virol.2010.04.003⟩. ⟨hal-02665665⟩
  • Agnès Vendeville, Marc Ravallec, Fran?oise-Xavi?re Jousset, Micheline Devise, Doriane Mutuel, et al.. Densovirus infectious pathway requires clathrin-mediated endocytosis followed by trafficking to the nucleus. Journal of Virology, American Society for Microbiology, 2009, 83 (9), pp.4678-4689. ⟨10.1128/JVI.02401-08⟩. ⟨hal-02661430⟩
  • I. Landais, Marie Helene Ogliastro, M. Duonor-Cérutti, T. Shimada, P. Fournier, et al.. Annotation pattern of ESTs from Spodoptera frugiperda Sf9 cells and analysis of the ribosomal protein genes reveal insect specific features and unexpectedly low codon usage bias. Bioinformatics, Oxford University Press (OUP), 2003, 19, pp.1-8. ⟨hal-02674127⟩
  • I. Landais, J.M. Pommet, Kasuei Mita, J. Nohata, S. Gimenez, et al.. Characterization of the cDNA encoding the 90 kDa heat-shock protein in the Lepidoptera Bombyx mori and Spodoptera frugiperda. Gene, Elsevier, 2001, 271, pp.223-231. ⟨hal-02675968⟩
  • J Direnzo, M Söderstrom, R Kurokawa, Marie Helene Ogliastro, M Ricote, et al.. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Molecular and Cellular Biology, American Society for Microbiology, 1997, 17 (4), pp.2166-2176. ⟨10.1128/MCB.17.4.2166⟩. ⟨hal-03735675⟩
  • C. Glass, M. Rosenfeld, D. Rose, R. Kurokawa, Y. Kamel, et al.. Mechanisms of transcriptional activation by retinoic acid receptors. Biochemical Society Transactions, Portland Press, 1997, 25 (2), pp.602-605. ⟨10.1042/bst0250602⟩. ⟨hal-03735821⟩
  • H. Chaabihi, Marie Helene Ogliastro, M. Martin, C. Giraud, Gerard Devauchelle, et al.. Competition between baculovirus polyhedrin and p10 gene expression during infection of insect cells. Journal of Virology, American Society for Microbiology, 1993, 67 (5), pp.2664-2671. ⟨hal-02699792⟩

Conference papers2 documents

  • Franck Dorkeld, Bernhard Gschloessl, Carole Kerdelhue, Rejane Streiff, Bernard Duvic, et al.. Exploration of viral communities associated with lepidoptera : A study of Thaumetopoea pityocampa (Notodontidae) and the European corn borer species complex Ostrinia nubilalis / O. scapulalis. 10. International Workshop on the Molecular Biology and Genetics of the Lepidoptera, University of Rhode Island. Kingston, USA. National Centre for Scientific Research Demokritos (NCSR Demokritos), GRC., Aug 2018, Crête, Greece. ⟨hal-02154688⟩
  • Fabrice Legeai, Stéphanie Robin, Marie Helene Ogliastro, Isabelle Darboux. Identification of differentially expressed long non-coding RNAs (lncRNAs) in response to viral infection in S. frugiperda hemocytes. 10. International Workshop on Molecular Biology and Genetics of the Lepidoptera, Aug 2018, Kolympari, Greece. ⟨hal-01988642⟩

Book sections1 document

  • Sarah François, Denis Filloux, Emmanuel Fernandez, Marie Helene Ogliastro, Philippe Roumagnac. Viral Metagenomics Approaches for High-Resolution Screening of Multiplexed Arthropod and Plant Viral Communities. Viral Metagenomics: Methods and Protocols, 1746, Humana Press Inc., 217 p., 2018, Methods in Molecular Biology, 978-1-4939-7683-6; 978-1-4939-7682-9. ⟨10.1007/978-1-4939-7683-6_7⟩. ⟨hal-02154687⟩

Preprints, Working Papers, ...1 document

  • Deborah Garcia, Doriane Mutuel, Mylène Ogliastro, Guillaume Cambray. CAPSID PROTEINS ARE NECESSARY FOR REPLICATION OF A DENSOVIRUS. 2020. ⟨hal-02941787⟩