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Role of reactive oxygen species in atherosclerosis: Lessons from murine genetic models
Anne Nègre-Salvayre
,
Paul Guerby
,
Stéphanie Gayral
,
Muriel Laffargue
,
Robert Salvayre
Article dans une revue
hal-02414348v1
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Serum IF1 concentration is independently associated to HDL levels and to coronary heart disease: the GENES study.
Annelise Genoux
,
Jean-Bernard Ruidavets
,
Jean Ferrières
,
Guillaume Combes
,
Laeticia Lichtenstein
,
et al.
Article dans une revue
inserm-01055265v1
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PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.
Romy Walser
,
John E. Burke
,
Elena Gogvadze
,
Thomas Bohnacker
,
Xuxiao Zhang
,
et al.
Article dans une revue
inserm-01055308v1
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Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.
Anne Fougerat
,
Natalia F. Smirnova
,
Stéphanie Gayral
,
Nicole Malet
,
Emilio Hirsch
,
et al.
Article dans une revue
inserm-01054873v1
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Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response
Natalia F. Smirnova
,
Stéphanie Gayral
,
Christophe Pedros
,
Gervaise Loirand
,
Nathalie Vaillant
,
et al.
Article dans une revue
hal-02519407v1
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A Function for Phosphoinositide 3-Kinase β Lipid Products in Coupling βγ to Ras Activation in Response to Lysophosphatidic Acid
Armelle Yart
,
Serge Roche
,
Reinhard Wetzker
,
Muriel Laffargue
,
Nicholas Tonks
,
et al.
Article dans une revue
hal-03191860v1
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A non-catalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage
Adrien Lupieri
,
Régis Blaise
,
Alessandra Ghigo
,
Natalia Smirnova
,
Marie-Kerguelen Sarthou
,
et al.
Article dans une revue
hal-02999224v1
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Phosphoinositide 3-kinase and integrin signalling are involved in activation of Bruton tyrosine kinase in thrombin-stimulated platelets
Muriel Laffargue
,
Jeannie M.F. Ragab-Thomas
,
Ashraf Ragab
,
Joel Tuech
,
Karine Missy
,
et al.
Article dans une revue
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hal-03192171v1
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Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low‐Density Lipoproteins and Increasing Their Uptake by Macrophages
Ekaterina Demina
,
Victoria Smutova
,
Xuefang Pan
,
Anne Fougerat
,
Tianlin Guo
,
et al.
Article dans une revue
hal-03445477v1
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Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.
Anne Fougerat
,
Stéphanie Gayral
,
Pierre Gourdy
,
Alexia Schambourg
,
Thomas Rückle
,
et al.
Article dans une revue
hal-00324678v1
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Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation
Qinyu Yao
,
Marie-Ange Renault
,
Candice Chapouly
,
Soizic Vandierdonck
,
Isabelle Belloc
,
et al.
Blood, 2014, pp.123(15)2429-2437
Article dans une revue
inserm-01159066v1
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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
Alessandra Ghigo
,
Alessandra Murabito
,
Valentina Sala
,
Anna Rita Pisano
,
Serena Bertolini
,
et al.
Article dans une revue
hal-03717907v1
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Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cells
Rana Zahreddine
,
Morgane Davezac
,
Natalia Smirnova
,
Melissa Buscato
,
Emeline Lhuillier
,
et al.
Article dans une revue
hal-03040722v1
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Smooth muscle cells-derived CXCL10 prevents endothelial healing through PI3Kγ-dependent T cells response
Adrien Lupieri
,
Natalia F. Smirnova
,
Romain Solinhac
,
Nicole Malet
,
Mehdi Benamar
,
et al.
Article dans une revue
hal-02349692v1
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Elastin fragmentation and atherosclerosis progression: The elastokine concept
Pascal Maurice
,
Sébastien Blaise
,
Stéphanie Gayral
,
Laurent Debelle
,
Muriel Laffargue
,
et al.
Article dans une revue
istex
hal-02347636v1
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17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo.
Bertrand Calippe
,
Victorine Douin-Echinard
,
Laurent Delpy
,
Muriel Laffargue
,
Karine Lélu
,
et al.
Article dans une revue
inserm-00504327v1
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Noncatalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage
A. Lupieri
,
R. Blaise
,
A. Ghigo
,
N. Smirnova
,
M.-K. Sarthou
,
et al.
Article dans une revue
hal-02817436v1
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Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway.
Stephanie Gayral
,
Roselyne Garnotel
,
Audrey Castaing-Berthou
,
Sébastien Blaise
,
Anne Fougerat
,
et al.
Article dans une revue
inserm-01055258v1
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Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway.
Bertrand Calippe
,
Victorine Douin-Echinard
,
Muriel Laffargue
,
Henrik Laurell
,
Vanessa Rana-Poussine
,
et al.
Journal of Immunology, 2008, 180 (12), pp.7980-8
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hal-00321739v1
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Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport.
Laeticia Lichtenstein
,
Nizar Serhan
,
Wijtske Annema
,
Guillaume Combes
,
Bernard Robaye
,
et al.
Article dans une revue
inserm-01055313v1
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Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE(2).Ki Mice Fed a High-Fat Diet
Cecile Vindis
,
Muriel Laffargue
,
Veronique Mateo
,
Berthold Buechele
,
Monica Rubio Ayala
,
et al.
Article dans une revue
hal-01543968v1
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Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake.
Véronique Pons
,
Nizar Serhan
,
Stéphanie Gayral
,
Camille Malaval
,
Michel Nauze
,
et al.
Article dans une revue
inserm-01054871v1
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The different natural estrogens promote endothelial healing through distinct cell targets
Morgane Davezac
,
Rana Zahreddine
,
Melissa Buscato
,
Natalia F. Smirnova
,
Chanaëlle Febrissy
,
et al.
Article dans une revue
hal-04040711v1
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A Critical Role for Phosphoinositide 3-Kinase Upstream of Gab1 and SHP2 in the Activation of Ras and Mitogen-activated Protein Kinases by Epidermal Growth Factor
Armelle Yart
,
Muriel Laffargue
,
Patrick Mayeux
,
Stany Chretien
,
Christine Pérès
,
et al.
Article dans une revue
hal-03191837v1
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Integrin-Dependent Tyrosine Phoshorylation and Cytoskeletal Translocation of Tec in Thrombin-Activated Platelets
Muriel Laffargue
,
Laurent Monnereau
,
Joël Tuech
,
Ashraf Ragab
,
Jeannie Ragab-Thomas
,
et al.
Article dans une revue
istex
hal-03192189v1
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Immune and Smooth Muscle Cells Interactions in Atherosclerosis: How to Target a Breaking Bad Dialogue?
Damien Ramel
,
Stéphanie Gayral
,
Marie-Kerguelen Sarthou
,
Nathalie Augé
,
Anne Nègre-Salvayre
,
et al.
Article dans une revue
hal-02999228v1
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The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells
Natalia F. Smirnova
,
Coralie Fontaine
,
Melissa Buscato
,
Adrien Lupieri
,
Alexia Vinel
,
et al.
Article dans une revue
hal-02640511v1
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A historical view of estrogen effect on arterial endothelial healing: From animal models to medical implication
Rana Zahreddine
,
Morgane Davezac
,
Melissa Buscato
,
Natalia Smirnova
,
Muriel Laffargue
,
et al.
Article dans une revue
hal-03758863v1
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PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress
Asma Boukhalfa
,
Anna Chiara Nascimbeni
,
Damien Ramel
,
Nicolas Dupont
,
Emilio Hirsch
,
et al.
Article dans une revue
inserm-02493884v1
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Elastic fibers and elastin receptor complex: Neuraminidase-1 takes the center stage
Amar Bennasroune
,
Beatrice Romier-Crouzet
,
Sébastien Blaise
,
Muriel Laffargue
,
Roman G Efremov
,
et al.
Article dans une revue
hal-02347367v1
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