|
Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2
Anastasiia T Davletgildeeva
,
Timofey E Tyugashev
,
Mingxing Zhao
,
Nikita A Kuznetsov
,
Alexander A Ishchenko
Article dans une revue
hal-04289624v1
|
|
NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells
Umit Aliyaskarova
,
Yeldar Baiken
,
Flore Renaud
,
Sophie Couve
,
Alexei Kisselev
Article dans une revue
hal-04289483v1
|
|
Abasic site–peptide cross-links are blocking lesions repaired by AP endonucleases
Anna V Yudkina
,
Nikita A Bulgakov
,
Daria V Kim
,
Svetlana V Baranova
,
Alexander A Ishchenko
Article dans une revue
hal-04289451v1
|
|
Chargaff’s second parity rule lies at the origin of additive genetic interactions in quantitative traits to make omnigenic selection possible
Bakhyt T Matkarimov
,
Murat K Saparbaev
Article dans une revue
hal-04425843v1
|
|
Kinetic Features of 3′–5′–Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from Saccharomyces cerevisiae
Aleksandra A Kuznetsova
,
Anastasia A Gavrilova
,
Alexander A Ishchenko
,
Murat Saparbaev
,
Olga S Fedorova
Article dans une revue
hal-04289790v1
|
|
Cloning and characterization of the major AP endonuclease from Staphylococcus aureus
Aigerim Turgimbayeva
,
Ulan Zein
,
Dmitry Zharkov
,
Yerlan Ramankulov
,
Murat Saparbaev
Article dans une revue
hal-03858686v1
|
|
Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy
Lyubov Yu. Kanazhevskaya
,
Denis Smyshliaev
,
Nadezhda Timofeyeva
,
Alexander Ishchenko
,
Murat Saparbaev
Article dans une revue
hal-03858651v1
|
|
Comparative Analysis of Exo- and Endonuclease Activities of APE1-like Enzymes
Anastasiia Davletgildeeva
,
Alexandra Kuznetsova
,
Darya Novopashina
,
Alexander Ishchenko
,
Murat Saparbaev
Article dans une revue
hal-03859362v1
|
|
Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease
Artemiy Bakman
,
Alexander Ishchenko
,
Murat Saparbaev
,
Olga Fedorova
,
Nikita Kuznetsov
Article dans une revue
hal-03858673v1
|
|
The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli
Svetlana I Senchurova
,
Aleksandra A Kuznetsova
,
Alexander A Ishchenko
,
Murat Saparbaev
,
Olga S Fedorova
Article dans une revue
hal-03858645v1
|
|
Role of Base Excision Repair Pathway in the Processing of Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs
Yeldar Baiken
,
Damira Kanayeva
,
Sabira Taipakova
,
Regina Groisman
,
Alexander A Ishchenko
Article dans une revue
hal-03432685v1
|
|
Evolutionary origins of DNA repair pathways: Role of oxygen catastrophe in the emergence of DNA glycosylases
Paulina Prorok
,
Inga R Grin
,
Bakhyt T Matkarimov
,
Alexander A Ishchenko
,
Jacques Laval
Article dans une revue
hal-04289943v2
|
|
Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases
Alexandra A Kuznetsova
,
Svetlana I Senchurova
,
Alexander Ishchenko
,
Murat A Saparbaev
,
Olga S Fedorova
Article dans une revue
hal-03432659v1
|
|
An Assay for the Activity of Base Excision Repair Enzymes in Cellular Extracts Using Fluorescent DNA Probes
O. A Kladova
,
D. A Iakovlev
,
R. Groisman
,
A. Ishchenko
,
M. K Saparbaev
Article dans une revue
hal-03068193v1
|
|
The Arabidopsis thaliana Poly(ADP-Ribose) Polymerases 1 and 2 Modify DNA by ADP-Ribosylating Terminal Phosphate Residues
Sabira Taipakova
,
Aigerim Kuanbay
,
Christine Saint-Pierre
,
Didier Gasparutto
,
Yeldar Baiken
Article dans une revue
hal-03432679v1
|
|
Reading targeted DNA damage in the active demethylation pathway: role of accessory domains of eukaryotic AP endonucleases and thymine-DNA glycosylases
Alexander V Popov
,
Inga R Grin
,
Antonina P Dvornikova
,
Bakhyt T Matkarimov
,
Regina Groisman
Article dans une revue
hal-03060641v1
|
|
Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins
Olga A Kladova
,
Irina V Alekseeva
,
Murat A Saparbaev
,
Olga S Fedorova
,
Nikita A Kuznetsov
Article dans une revue
hal-03066830v1
|
|
Wheat Germination Is Dependent on Plant Target of Rapamycin Signaling
Bauyrzhan Smailov
,
Sanzhar Alybayev
,
Izat Smekenov
,
Aibek Mursalimov
,
Murat A Saparbaev
Article dans une revue
hal-03432696v2
|
|
DNA-Histone Cross-Links: Formation and Repair
Manideep C Pachva
,
Alexei F Kisselev
,
Bakhyt T Matkarimov
,
Murat A Saparbaev
,
Regina Groisman
Article dans une revue
hal-03432690v1
|
|
Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage
Bakhyt Matkarimov
,
Dmitry Zharkov
,
Murat Saparbaev
Article dans une revue
hal-02392725v1
|
|
Mechanism of stimulation of DNA binding of the transcription factors by human apurinic/apyrimidinic endonuclease 1, APE1
Milena Bazlekowa-Karaban
,
Paulina Prorok
,
Sonia Baconnais
,
Sabira Taipakova
,
Zhiger Akishev
Article dans une revue
hal-02322130v1
|
|
The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation
Olga Kladova
,
Milena Bazlekowa-Karaban
,
Sonia Baconnais
,
Olivier Pietrement
,
Alexander Ishchenko
Article dans une revue
hal-02322373v1
|
|
Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori
Aigerim Turgimbayeva
,
Sailau Abeldenov
,
Dmitry Zharkov
,
Alexander Ishchenko
,
Yerlan Ramankulov
Article dans une revue
hal-02322329v1
|
|
Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in Escherichia coli
Caroline Zutterling
,
Aibek Mursalimov
,
Ibtissam Talhaoui
,
Zhanat Koshenov
,
Zhiger Akishev
Article dans une revue
hal-02322261v1
|
|
Pre-steady-state kinetic analysis of damage recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1
Alexandra Kuznetsova
,
Danila Iakovlev
,
Inna Misovets
,
Alexander Ishchenko
,
Murat Saparbaev
Article dans une revue
hal-02393555v1
|
|
Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases
Ibtissam Talhaoui
,
Bakhyt Matkarimov
,
Thierry Tchenio
,
Dmitry Zharkov
,
Murat Saparbaev
Article dans une revue
hal-02393543v1
|
|
The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure
Peter Martin
,
Sophie Couvé
,
Caroline Zutterling
,
Mustafa Albelazi
,
Regina Groisman
Article dans une revue
hal-02393493v1
|
|
The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway
Zhiger Akishev
,
Sabira Taipakova
,
Botagoz Joldybayeva
,
Caroline Zutterling
,
Izat Smekenov
Article dans une revue
hal-02393578v1
|
|
TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis
Emna Mahfoudhi
,
Ibtissam A Talhaoui
,
Xenia Cabagnols
,
Véronique Della Valle
,
Lise Secardin
Article dans une revue
pasteur-01405648v1
|
|
Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.
Modesto Redrejo-Rodríguez
,
Armelle Vigouroux
,
Aibek Mursalimov
,
Inga Grin
,
Doria Alili
Biochimie, 2016
Article dans une revue
hal-01356083v1
|
|
Characterization of DNA substrate specificities of apurinic/apyrimidinic endonucleases from Mycobacterium tuberculosis
Vladimir Shafirovich
,
Zhi Liu
,
Christine Saint-Pierre
,
Zhiger Akishev
,
Bakhyt Matkarimov
Article dans une revue
hal-02393612v1
|
|
Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1
Alexandra Kuznetsova
,
Nikita Kuznetsov
,
Alexander Ishchenko
,
Murat Saparbaev
,
Olga Fedorova
Article dans une revue
hal-02393724v1
|
|
Lipid peroxidation product 4-hydroxy-2-nonenal modulates base excision repair in human cells
Alicja Winczura
,
Alicja Czubaty
,
Kinga Winczura
,
Katarzyna Masłowska
,
Matylda Nałęcz
Article dans une revue
hal-02393629v1
|
|
Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3′-diesterase-deficient strain
Zhiqiang Wang
,
Emily Ayoub
,
Abdelghani Mazouzi
,
Inga Grin
,
Alexander Ishchenko
Article dans une revue
hal-02393647v1
|
|
Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
Botagoz Joldybayeva
,
Paulina Prorok
,
Inga Grin
,
Dmitry Zharkov
,
Alexander Ishenko
Article dans une revue
hal-02393740v1
|
|
Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase
Alexandra Kuznetsova
,
Nikita Kuznetsov
,
Alexander Ishchenko
,
Murat Saparbaev
,
Olga Fedorova
Article dans une revue
hal-02393729v1
|
|
Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands
Ibtissam Talhaoui
,
Sophie Couvé
,
Laurent Gros
,
Alexander Ishchenko
,
Bakhyt Matkarimov
Article dans une revue
hal-02393707v1
|
|
The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs
Natalia Lebedeva
,
Nadejda Rechkunova
,
Alexander Ishchenko
,
Murat Saparbaev
,
Olga Lavrik
Article dans une revue
hal-02393777v1
|
|
Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase
Alexandra Kuznetsova
,
Nikita Kuznetsov
,
Olga Fedorova
,
Rustem Kasymov
,
Inga Grin
Article dans une revue
hal-02393785v1
|
|
Direct DNA Lesion Reversal and Excision Repair in Escherichia coli
Sophie Couvé
,
Jacques Laval
,
Erlan Ramanculov
,
Olga Fedorova
,
Alexander Ishchenko
Article dans une revue
hal-02393792v1
|
|
7,8-dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases
Ibtissam Talhaoui
,
Sophie Couvé
,
Alexander Ishchenko
,
Christophe Kunz
,
Primo Schär
Article dans une revue
hal-02393748v1
|
|
Highly Mutagenic Exocyclic DNA Adducts Are Substrates for the Human Nucleotide Incision Repair Pathway
Paulina Prorok
,
Christine Saint-Pierre
,
Didier Gasparutto
,
Olga Fedorova
,
Alexander Ishchenko
Article dans une revue
hal-02368498v1
|
|
New Insights in the Removal of the Hydantoins, Oxidation Product of Pyrimidines, via the Base Excision and Nucleotide Incision Repair Pathways
Modesto Redrejo-Rodríguez
,
Christine Saint-Pierre
,
Sophie Couvé
,
Abdelghani Mazouzi
,
Alexander Ishchenko
Article dans une revue
cea-02074458v1
|
|
Crystallization and preliminary X-ray analysis of human endonuclease 1 (APE1) in complex with an oligonucleotide containing a 5,6-dihydrouracil (DHU) or an alpha-anomeric 2'-deoxyadenosine (alphadA) modified base.
Pascal Retailleau
,
Alexander A Ishchenko
,
Nikita A Kuznetsov
,
Murat Saparbaev
,
Solange Moréra
Acta crystallographica Section F : Structural biology communications [2014-..], 2010, 66 (Pt 7), pp.798-800. ⟨10.1107/S1744309110017021⟩
Article dans une revue
hal-00512071v1
|
|
Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.
Alexander A Ishchenko
,
Eric Deprez
,
Andrei V. Maksimenko
,
Jean-Claude Brochon
,
Patrick Tauc
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (8), pp.2564-9. ⟨10.1073/pnas.0508582103⟩
Article dans une revue
hal-00216010v1
|
|
Apoptotic Topoisomerase I-DNA Complexes Induced by Staurosporine-mediated Oxygen Radicals
Olivier Sordet
,
Qasim Khan
,
Isabelle Plo
,
Philippe Pourquier
,
Yoshimasa Urasaki
Article dans une revue
inserm-02438646v1
|
|
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.
Laurent Gros
,
Alexander A Ishchenko
,
Hiroshi Ide
,
Rhoderick H Elder
,
Murat K Saparbaev
Article dans une revue
hal-00277634v1
|