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Mounir TAREK


Mounir Tarek
CNRS section 13, DR1
Senior Research Director


Laboratoire de Physique et Chimie Théoriques
UMR 7019 LPCT Université de Lorraine, 
Boulevard des Aiguillettes, BP 70239 
54506 Vandoeuvre-lès-Nancy, cedex France
tel: +33 (0) 3-72-74-52 74

RESEARCH INTERESTSimulation of model membranes and membrane bound species is in biophysics a frontier area of research seething with excitements and challenges. The availability of all the ingredients to investigate membranes, in-silico, opens new perspectives particularly in the biological front. The aim of my research is to take computer simulations to an extra level, where manipulation of molecular nano-objects in-silico, by reproducing realistic mechanisms, sheds light onto challenging multidisciplinary problems. TOPICS • Electroporation of cell membranes (drug and gene delivery, electroshock healing, antibacterial treatment).... • Transport through voltage-gated potassium ion channels (ion conduction and selectivity, regulation, mutations, chanellopathies) • Action of synthetic peptides on membranes (antibacterial action) • Interaction of carbon nanostructures with membranes and membrane proteins. • Membrane Oxidation, Mecanisms. • Development of Coarse grained force fields for biomolecular simulation
   

 

 


Gildas Loussouarn   

Journal articles1 document

  • Audrey Deyawe, Marina A. Kasimova, Lucie Delemotte, Gildas Loussouarn, Mounir Tarek. Studying Kv Channels Function using Computational Methods. Methods in Molecular Biology, Humana Press/Springer Imprint, 2018, Equipe IIa, 1684, pp.321--341. ⟨10.1007/978-1-4939-7362-0_24⟩. ⟨hal-01833334⟩