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Microwave-assisted efficient synthesis of 1,2-diaryldiketones: a novel oxidation reaction of diarylalkynes with DMSO promoted by FeBr3

Anne Giraud , Olivier Provot , Jean-François Peyrat , Mouad Alami , Jean-Daniel Brion
Tetrahedron, 2006, 62 (33), pp.7667-7673. ⟨10.1016/j.tet.2006.05.072⟩
Article dans une revue hal-02394615v1
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p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles

Maud Jacubert , Olivier Provot , Jean-François Peyrat , Abdallah Hamze , Jean-Daniel Brion , et al.
Tetrahedron, 2010, 66 (21), pp.3775-3787. ⟨10.1016/j.tet.2010.03.055⟩
Article dans une revue hal-02394573v1
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Unexpected Oxidative Ring Opening of Electron-Rich 3-Aminobenzofurans into α-Ketoimines Derivatives

Ilhem Khelifi , Guangkuan Zhao , Nour-Eddine Ghermani , Olivier Provot , Mouad Alami
Journal of Organic Chemistry, 2019, 84 (4), pp.1725-1733. ⟨10.1021/acs.joc.8b01685⟩
Article dans une revue hal-02394232v1

Selective Palladium-Catalyzed Domino Heck/Buchwald-Hartwig Arylations of N -Glycosylcinnamamides: An Efficient Route to 4-Aryl- N -glycosylquinolin-2-ones

Thi Thanh Huyen Luong , Sabrina Touchet , Mouad Alami , Samir Messaoudi
Advanced Synthesis and Catalysis, 2017, 359 (8), pp.1320-1330. ⟨10.1002/adsc.201601382⟩
Article dans une revue hal-02031374v1
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Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation

Shannon Pecnard , Olivier Provot , Hélène Levaique , Jérome Bignon , Laurie Askenatzis , et al.
European Journal of Medicinal Chemistry, 2021, 209, pp.112873. ⟨10.1016/j.ejmech.2020.112873⟩
Article dans une revue hal-03034493v1
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Anticancer Properties of Indole Derivatives as IsoCombretastatin A-4 analogues

Shannon Pecnard , Abdallah Hamze , Jérome Bignon , Bastien Prost , Alain Deroussent , et al.
European Journal of Medicinal Chemistry, 2021, 223, pp.113656. ⟨10.1016/j.ejmech.2021.113656⟩
Article dans une revue hal-03349143v1

Synthesis of 2-(1-phenylvinyl)benzofurans and 2-(1-phenylvinyl)indoles as antimitotic agents by a tandem palladium-assisted coupling-cyclization reaction between 1-phenylvinyl iodides and ortho-substituted arylalkynes

Bret Tréguier B. , Evelia Rasolofonjatovo , Abdallah Hamze , Olivier Provot , Joanna Wdzieczak-Bakala , et al.
European Journal of Organic Chemistry, 2011, 25, pp.4868-4876
Article dans une revue hal-00647619v1

An efficient coupling of N-tosylhydrazones with 2-halopyridines: synthesis of 2-α-styrylpyridines endowed with antitumor activity.

Marie Lawson , Abdallah Hamze , Jean-François Peyrat , Jérôme Bignon , Joelle Dubois , et al.
Organic & Biomolecular Chemistry, 2013, 11 (22), pp.3664-73. ⟨10.1039/c3ob40263k⟩
Article dans une revue hal-00853049v1
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Synthesis and biological activities of pyrazino[1,2-a]indole and pyrazino[1,2-a]indol-1-one derivatives

Kena Zhang , Christine Tran , Mouad Alami , Abdallah Hamze , Olivier Provot
Pharmaceuticals, 2021, 14 (8), pp.779. ⟨10.3390/ph14080779⟩
Article dans une revue hal-03349178v1
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Synthesis of Isocoumarin via PTSA-Catalyzed Annulation of Diarylalkynes

Gaëlle Le Bras , Abdallah Hamze , Samir Messaoudi , Olivier Provot , Pierre-Benoît Le Calvez , et al.
Synthesis: Journal of Synthetic Organic Chemistry, 2008, 2008 (10), pp.1607-1611. ⟨10.1055/s-2008-1072575⟩
Article dans une revue hal-02394596v1
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Synthesis of 2,3-Substituted β- N -Glycosyl Indoles through C–H Activation/Annulation Process under Rh(III)-Catalysis

Guangkuan Zhao , Mingxiang Zhu , Olivier Provot , Mouad Alami , Samir Messaoudi
Organic Letters, 2020, 22 (1), pp.57-61. ⟨10.1021/acs.orglett.9b03893⟩
Article dans une revue hal-03036320v1

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso -Combretastatin A-4

Diana Lamaa , Hsin-Ping Lin , Lena Zig , Cyril Bauvais , Guillaume Bollot , et al.
Journal of Medicinal Chemistry, 2018, 61 (15), pp.6574-6591. ⟨10.1021/acs.jmedchem.8b00050⟩
Article dans une revue hal-02309817v1

The metabolic fate of isocombretastatin A-4 in human liver microsomes: identification, synthesis and biological evaluation of metabolites.

Mohamed Ali Soussi , Silvio Aprile , Samir Messaoudi , Olivier Provot , Erika del Grosso , et al.
ChemMedChem, 2011, 6 (10), pp.1781-1788. ⟨10.1002/cmdc.201100193⟩
Article dans une revue istex hal-00649286v1
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N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents

Ilhem Khelifi , Timothée Naret , Abdallah Hamze , Jérôme Bignon , Hélène Lévaique , et al.
European Journal of Medicinal Chemistry, 2019, 168, pp.176-188. ⟨10.1016/j.ejmech.2019.02.038⟩
Article dans une revue hal-02394208v1
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Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4

Evelia Rasolofonjatovo , Olivier Provot , Abdallah Hamze , Jérôme Bignon , Sylviane Thoret , et al.
European Journal of Medicinal Chemistry, 2010, 45 (9), pp.3617-3626. ⟨10.1016/j.ejmech.2010.05.007⟩
Article dans une revue istex hal-02394481v1
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Palladium-Catalyzed Coupling of 3-Halo-Substituted Coumarins, Chromenes, and Quinolones with Various Nitrogen-Containing Nucleophiles

Mohamed Ali Soussi , Davide Audisio , Samir Messaoudi , Olivier Provot , Jean-Daniel Brion , et al.
European Journal of Organic Chemistry, 2011, 2011 (26), pp.5077-5088. ⟨10.1002/ejoc.201100480⟩
Article dans une revue istex hal-02394445v1
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One-pot hydrosilylation–protodesilylation of functionalized diarylalkynes: a highly selective access to Z-stilbenes. Application to the synthesis of combretastatin A-4

Anne Giraud , Olivier Provot , Abdallah Hamze , Jean-Daniel Brion , Mouad Alami
Tetrahedron Letters, 2008, 49 (7), pp.1107-1110. ⟨10.1016/j.tetlet.2007.12.057⟩
Article dans une revue hal-02394604v1
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Recent Advances in Transition-Metal-Catalyzed Functionalization of 1-Thiosugars

Nada Ibrahim , Mouad Alami , Samir Messaoudi
Asian Journal of Organic Chemistry, 2018, 7 (10), pp.2026-2038. ⟨10.1002/ajoc.201800449⟩
Article dans une revue hal-02414169v1

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation

Timothée Naret , Ilhem Khelifi , Olivier Provot , Jérôme Bignon , Hélène Lévaique , et al.
Journal of Medicinal Chemistry, 2019, 62 (4), pp.1902-1916. ⟨10.1021/acs.jmedchem.8b01386⟩
Article dans une revue hal-02123778v1
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IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity

Mohamed Ali Soussi , Olivier Provot , Guillaume Bernadat , Jérôme Bignon , Déborah Desravines , et al.
ChemMedChem, 2015, 10 (8), pp.1392-1402. ⟨10.1002/cmdc.201500069⟩
Article dans une revue istex hal-02394367v1
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One-Pot Assembly of Unsymmetrical Biaryl Thioglycosides through Chemoselective Palladium-Catalyzed Three-Component Tandem Reaction

Sara Benmahdjoub , Nada Ibrahim , Belkacem Benmerad , Mouad Alami , Samir Messaoudi
Organic Letters, 2018, 20 (13), pp.4067-4071. ⟨10.1021/acs.orglett.8b01624⟩
Article dans une revue hal-02414163v1

Pd-Catalyzed Reaction of Sterically Hindered Hydrazones with Aryl Halides: Synthesis of Tetra-Substituted Olefins Related to iso -Combretastatin A4

Etienne Brachet , Abdallah Hamze , Jean-François Peyrat , Jean-Daniel Brion , Mouad Alami
Organic Letters, 2010, 12 (18), pp.4042-4045. ⟨10.1021/ol101639g⟩
Article dans une revue hal-03073857v1
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Room-Temperature Pd-Catalyzed Synthesis of 1-(Hetero)aryl Selenoglycosides

Mingxiang Zhu , Mouad Alami , Samir Messaoudi
Organic Letters, 2020, 22 (16), pp.6584-6589. ⟨10.1021/acs.orglett.0c02352⟩
Article dans une revue hal-03036512v1

Isoginkgetin derivative IP2 enhances the adaptive immune response against tumor antigens

Romain Darrigrand , Alison Pierson , Marine Rouillon , Dolor Renko , Mathilde Boulpicante , et al.
Communications Biology, 2021, 4 (1), ⟨10.1038/s42003-021-01801-2⟩
Article dans une revue hal-03396797v1

Nickel-Catalyzed Arylation, Alkenylation, and Alkynylation of Unprotected Thioglycosides at Room Temperature

Etienne Brachet , Jean-Daniel Brion , Mouad Alami , Samir Messaoudi
Chemistry - A European Journal, 2013, 19 (45), pp.15276-15280. ⟨10.1002/chem.201302999⟩
Article dans une revue istex hal-03073844v1
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De nouvelles perspectives en thérapie antivasculaire Pourquoi faire compliquer quand on peut faire simple ?

Mouad Alami
Chimie et biologie de synthèse. Les applications, 2019, ⟨10.1051/978-2-7598-2316-1.c017⟩
Chapitre d'ouvrage hal-02414134v1
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Copper-Catalyzed Anomeric O-Arylation of Carbohydrate Derivatives at Room Temperature

Tristan Verdelet , Sara Benmahdjoub , Belkacem Benmerad , Mouad Alami , Samir Messaoudi
Journal of Organic Chemistry, 2019, 84 (14), pp.9226-9238. ⟨10.1021/acs.joc.9b01218⟩
Article dans une revue hal-02396654v1
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Palladium mediated direct coupling of silylated arylalkynes with propargylic chlorides: an efficient access to functionalized conjugated allenynes

Delphine Girard , Sylvie Broussous , Olivier Provot , Jean-Daniel Brion , Mouad Alami
Tetrahedron Letters, 2007, 48 (34), pp.6022-6026. ⟨10.1016/j.tetlet.2007.06.079⟩
Article dans une revue hal-02394606v1
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Disproportionation reaction of diarylcarbinols: a versatile access to diarylmethanes speeded up using microwave irradiation

Nathalie L'Hermite , Anne Giraud , Olivier Provot , Jean-François Peyrat , Mouad Alami , et al.
Tetrahedron, 2006, 62 (51), pp.11994-12002. ⟨10.1016/j.tet.2006.09.083⟩
Article dans une revue hal-02394612v1

Tandem One-Pot Palladium-Catalyzed Coupling of Hydrazones, Haloindoles, and Amines: Synthesis of Amino-N-vinylindoles and Their Effect on Human Colon Carcinoma Cells.

Maxime Roche , Jérôme Bignon , Jean-Daniel Brion , Abdallah Hamze , Mouad Alami
Journal of Organic Chemistry, 2014, 79 (16), pp.7583-92. ⟨10.1021/jo501315q⟩
Article dans une revue hal-01065681v1