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Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial

 Maëva Cotinat , Isabelle Boquet , Moreno Ursino , Cécile Brocard , Elisabeth Jouve , et al.
PLoS ONE, 2023, 18, ⟨10.1371/journal.pone.0276892⟩
Article dans une revue hal-04087364v1

Postoperative analgesia after surgical repair of distal radius fracture: a randomized comparison between distal peripheral nerve blockade and surgical site infiltration

 Didier Sciard , Kailai Xu , Anne Soulier , Guillaume Dufour , Moreno Ursino , et al.
Minerva Anestesiologica, 2023, 89 (10), ⟨10.23736/s0375-9393.23.16956-2⟩
Article dans une revue hal-04336790v1

Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned

 Fabiola La Gamba , Tom Jacobs , Helena Geys , Thomas Jaki , Jan Serroyen , et al.
Pharmaceutical Statistics, 2019, pst.1941. ⟨10.1002/pst.1941⟩
Article dans une revue hal-03873772v1
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Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network

 Claire Dupuis , Etienne de Montmollin , Niccolò Buetti , Dany Goldgran-Toledano , Jean Reignier , et al.
PLoS ONE, 2021, 16 (8), pp.e0255644. ⟨10.1371/journal.pone.0255644⟩
Article dans une revue hal-03873780v1
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A straightforward meta‐analysis approach for oncology phase I dose‐finding studies

 Christian Röver , Moreno Ursino , Tim Friede , Sarah Zohar
Statistics in Medicine, 2022, 41 (20), pp.3915-3940. ⟨10.1002/sim.9484⟩
Article dans une revue hal-03864767v1
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Bayesian variable selection based on clinical relevance weights in small sample studies—Application to colon cancer

 Sandrine Boulet , Moreno Ursino , Peter F Thall , Anne-Sophie Jannot , Sarah Zohar
Statistics in Medicine, 2019, 38 (12), pp.2228-2247. ⟨10.1002/sim.8107⟩
Article dans une revue hal-02120840v1
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Bayesian dose‐regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics

 Emma Gerard , Sarah Zohar , Hoai‐thu Thai , Christelle Lorenzato , Marie‐karelle Riviere , et al.
Biometrics, 2022, ⟨10.1111/biom.13433⟩
Article dans une revue hal-03141298v1

DICE: A Bayesian model for early dose finding in phase I trials with multiple treatment courses

 Moreno Ursino , Lucie Biard , Sylvie Chevret
Biometrical Journal, In press, ⟨10.1002/bimj.202000369⟩
Article dans une revue hal-03873768v1

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

 Christina Yap , Olga Solovyeva , Johann de Bono , Jan Rekowski , Dhrusti Patel , et al.
BMJ - British Medical Journal, In press, pp.e076387. ⟨10.1136/bmj-2023-076387⟩
Article dans une revue hal-04336824v1

Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study

 Olga Solovyeva , Munyaradzi Dimairo , Christopher Weir , Siew Wan Hee , Aude Espinasse , et al.
BMC Medicine, 2023, 21 (1), pp.246. ⟨10.1186/s12916-023-02937-0⟩
Article dans une revue hal-04336816v1
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A new parsimonious model for ordinal longitudinal data with application to subjective evaluations of a gastrointestinal disease

 Moreno Ursino , Mauro Gasparini
Statistical Methods in Medical Research, 2018, 27 (5), pp.1376-1393. ⟨10.1177/0962280216661370⟩
Article dans une revue hal-03873777v1
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Full versus half dose of antenatal betamethasone to prevent severe neonatal respiratory distress syndrome associated with preterm birth: study protocol for a randomised, multicenter, double blind, placebo-controlled, non-inferiority trial (BETADOSE)

 Thomas Schmitz , Corinne Alberti , Moreno Ursino , Olivier Baud , Camille Aupiais
BMC Pregnancy and Childbirth, 2019, 19, pp.67. ⟨10.1186/s12884-019-2206-x⟩
Article dans une revue hal-02052145v1
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Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1) study protocol of a phase II trial

 Géraldine Favrais , Moreno Ursino , Catherine Mouchel , Estelle Boivin , Vincent Jullien , et al.
BMJ Open, 2019, 9 (1), pp.e022739. ⟨10.1136/bmjopen-2018-022739⟩
Article dans une revue hal-02049819v1

Bayesian knowledge integration for an in vitro–in vivo correlation model

 Elvira Erhardt , Moreno Ursino , Jeike Biewenga , Tom Jacobs , Mauro Gasparini
Biometrical Journal, 2019, 61 (5), pp.1104-1119. ⟨10.1002/bimj.201700263⟩
Article dans une revue hal-03873774v1

Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions

 Silvia Calderazzo , Sergey Tarima , Carissa Reid , Nancy Flournoy , Tim Friede , et al.
Statistics in Biopharmaceutical Research, 2023, pp.1-17. ⟨10.1080/19466315.2023.2211023⟩
Article dans une revue hal-04336804v1
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Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations

 Moreno Ursino , Sarah Zohar , Frederike Lentz , Corinne Alberti , Tim Friede , et al.
Biometrical Journal, 2017, 59 (4), pp.804-825. ⟨10.1002/bimj.201600084⟩
Article dans une revue hal-01560222v1
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A dose finding design for seizure reduction in neonates

 Moreno Ursino , Ying Yuan , Corinne Alberti , Emmanuelle Comets , Geraldine Favrais , et al.
Journal of the Royal Statistical Society: Series C Applied Statistics, 2019, 68 (2), pp.427-444. ⟨10.1111/rssc.12289⟩
Article dans une revue hal-03862983v1
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Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients

 Moreno Ursino , Claire Dupuis , Niccolò Buetti , Etienne de Montmollin , Lila Bouadma , et al.
Journal of Clinical Medicine, 2021, 10 (3), pp.544. ⟨10.3390/jcm10030544⟩
Article dans une revue hal-03134612v1

Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial

 Benjamin Duputel , Nigel Stallard , François Montestruc , Sarah Zohar , Moreno Ursino
Statistical Methods in Medical Research, 2023, 32 (5), pp.963-977. ⟨10.1177/09622802231160554⟩
Article dans une revue hal-04126394v1
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Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia

 Claire Dupuis , Lila Bouadma , Etienne de Montmollin , Dany Goldgran-Toledano , Carole Schwebel , et al.
Critical Care Explorations, 2021, 3 (1), pp.e0329. ⟨10.1097/CCE.0000000000000329⟩
Article dans une revue hal-03873783v1
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A Bayesian non-inferiority approach using experts’ margin elicitation – application to the monitoring of safety events

 Camille Aupiais , Corinne Alberti , Thomas Schmitz , Olivier Baud , Moreno Ursino , et al.
BMC Medical Research Methodology, 2019, 19 (1), pp.187. ⟨10.1186/s12874-019-0826-5⟩
Article dans une revue inserm-02456619v1

An adaptive power prior for sequential clinical trials – Application to bridging studies

 Adrien Ollier , Satoshi Morita , Moreno Ursino , Sarah Zohar
Statistical Methods in Medical Research, 2020, 29 (8), pp.2282-2294. ⟨10.1177/0962280219886609⟩
Article dans une revue hal-03863036v1
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Bayesian Approaches for Confirmatory Trials in Rare Diseases: Opportunities and Challenges

 Moreno Ursino , Nigel Stallard
International Journal of Environmental Research and Public Health, 2021, 18 (3), pp.1022. ⟨10.3390/ijerph18031022⟩
Article dans une revue hal-03124245v1
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L'équipe-projet HeKA

 Adrien Coulet , Stéphanie Allassonniere , François Angoulvant , Anita Burgun , Xiaoyi Chen , et al.
Bulletin de l'Association Française pour l'Intelligence Artificielle, 2021, 112, pp.29-32
Article dans une revue hal-03485904v1
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Bayesian treatment comparison using parametric mixture priors computed from elicited histograms

 Peter F Thall , Moreno Ursino , Véronique Baudouin , Corinne Alberti , Sarah Zohar
Statistical Methods in Medical Research, 2017, 28 (2), pp.404-418. ⟨10.1177/0962280217726803⟩
Article dans une revue hal-02016667v1
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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

 Robin Michelet , Moreno Ursino , Sandrine Boulet , Sebastian Franck , Fiordiligie Casilag , et al.
Pharmaceutics, 2021, 13 (5), pp.601. ⟨10.3390/pharmaceutics13050601⟩
Article dans une revue hal-03215662v1

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial

 Thomas Schmitz , Muriel Doret-Dion , Loic Sentilhes , Olivier Parant , Olivier Claris , et al.
The Lancet, 2022, 400 (10352), pp.592-604. ⟨10.1016/S0140-6736(22)01535-5⟩
Article dans une revue hal-03872891v1
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Conditional Non-parametric Bootstrap for Non-linear Mixed Effect Models

 Emmanuelle Comets , Christelle Rodrigues , Vincent Jullien , Moreno Ursino
Pharmaceutical Research, 2021, 38 (6), pp.1057-1066. ⟨10.1007/s11095-021-03052-6⟩
Article dans une revue hal-03280469v1
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Integration of elicited expert information via a power prior in Bayesian variable selection: Application to colon cancer data

 Sandrine Boulet , Moreno Ursino , Peter F Thall , Bruno Landi , Céline Lepere , et al.
Statistical Methods in Medical Research, 2020, 38 (12), Ahead of print. ⟨10.1177/0962280219841082⟩
Article dans une revue inserm-02456624v1
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Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies

 Caroline Petit , Adeline Samson , Satoshi Morita , Moreno Ursino , Vincent Jullien , et al.
Statistical Methods in Medical Research, 2018, 27 (6), pp.1860-1877. ⟨10.1177/0962280216671348⟩
Article dans une revue hal-01623760v1
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