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Converting monoclonal antibody-based immunotherapies from passive to active: bringing immune complexes into play

J. Lambour , M. Naranjo-Gomez , Marc Piechaczyk , M. Pelegrin
Emerging microbes & infections, 2016, 5 (8), pp.e92. ⟨10.1038/emi.2016.97⟩
Article dans une revue hal-02187332v1

Long-lasting protective antiviral immunity induced by passive immunotherapies requires both neutralizing and effector functions of the administered monoclonal antibody

R. Nasser , M. Pelegrin , H. A. Michaud , M. Plays , Marc Piechaczyk , et al.
Journal of Virology, 2010, 84 (19), pp.10169--81. ⟨10.1128/JVI.00568-10⟩
Article dans une revue hal-02193587v1
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A crucial role for infected-cell/antibody immune complexes in the enhancement of endogenous antiviral immunity by short passive immunotherapy

H. A. Michaud , T. Gomard , L. Gros , K. Thiolon , R. Nasser , et al.
PLoS Pathogens, 2010, 6 (6), pp.e1000948. ⟨10.1371/journal.ppat.1000948⟩
Article dans une revue hal-02193585v1

Sustained systemic delivery of monoclonal antibodies by genetically modified skin fibroblasts

D. Noel , M. Pelegrin , F. Brockly , A. H. Lund , Marc Piechaczyk
Journal of Investigative Dermatology, 2000, 115 (4), pp.740--5. ⟨10.1046/j.1523-1747.2000.00106.x⟩
Article dans une revue hal-02196823v1
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An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells

T. Gomard , H. A. Michaud , D. Tempe , K. Thiolon , M. Pelegrin , et al.
PLoS ONE, 2010, 5 (3), pp.e9585. ⟨10.1371/journal.pone.0009585⟩
Article dans une revue hal-02193436v1
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Anticorps monoclonaux en infectiologie Des nouveaux partenaires dans l'arsenal thérapeutique

Guillaume Desoubeaux , Mireia Pelegrin
Médecine/Sciences, 2019, Anticorps monoclonaux en thérapeutique, 35 (12), pp.1008 - 1013. ⟨10.1051/medsci/2019200⟩
Article dans une revue hal-02439405v1
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Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies

Mar Naranjo-Gomez , Jennifer Lambour , Marc Piechaczyk , Mireia Pelegrin
JCI Insight, 2018, 3 (9), ⟨10.1172/jci.insight.97339⟩
Article dans une revue hal-02187063v1
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Differential and sequential immunomodulatory role of neutrophils and Ly6C hi inflammatory monocytes during antiviral antibody therapy

Jennifer Lambour , Mar Naranjo-Gomez , Myriam Boyer-Clavel , Mireia Pelegrin
Emerging microbes & infections, 2021, 10 (1), pp.964-981. ⟨10.1080/22221751.2021.1913068⟩
Article dans une revue hal-03236619v1

Monoclonal antibody-based genetic immunotherapy

M. Pelegrin , L. Gros , H. Dreja , Marc Piechaczyk
Current Gene Therapy, 2004, 4 (3), pp.347--56. ⟨10.2174/1566523043346246⟩
Article dans une revue hal-02262385v1
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10th antibody industrial symposium: new developments in antibody and adoptive cell therapies

Ana Antunes , Luis Álvarez-Vallina , Federico Bertoglio , Nicolas Bouquin , Stéphanie Cornen , et al.
mAbs, 2023, 15 (1), pp.2211692. ⟨10.1080/19420862.2023.2211692⟩
Article dans une revue hal-04121982v1
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Vaccinal effect of HIV-1 antibody therapy

Mar Naranjo-Gomez , Mireia Pelegrin
Current Opinion in HIV and AIDS, 2019, 14 (4), pp.325-333. ⟨10.1097/COH.0000000000000555⟩
Article dans une revue hal-02403087v1
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Differential and sequential immunomodulatory role of neutrophils and Ly6Chi inflammatory monocytes during antiviral antibody therapy

Jennifer Lambour , Mar Naranjo-Gomez , Myriam Boyer-Clavel , Mireia Pelegrin
2020
Pré-publication, Document de travail hal-03047897v1
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Immunomodulatory Role of NK Cells during Antiviral Antibody Therapy

Mar Naranjo-Gomez , Marine Cahen , Jennifer Lambour , Myriam Boyer-Clavel , Mireia Pelegrin
Vaccines, 2021, 9 (2), pp.137. ⟨10.3390/vaccines9020137⟩
Article dans une revue hal-03215513v1

Control of regulatory T cells is necessary for vaccine-like effects of antiviral immunotherapy by monoclonal antibodies

R. Nasser , M. Pelegrin , M. Plays , L. Gros , Marc Piechaczyk
Blood, 2013, 121 (7), pp.1102--11. ⟨10.1182/blood-2012-06-432153⟩
Article dans une revue hal-02193666v1

In vitro and in vivo secretion of cloned antibodies by genetically modified myogenic cells

D. Noel , M. Pelegrin , M. Marin , M. Biard-Piechaczyk , J. C. Ourlin , et al.
Human Gene Therapy, 1997, 8 (10), pp.1219--29. ⟨10.1089/hum.1997.8.10-1219⟩
Article dans une revue hal-02194302v1

Genetically engineered antibodies in gene transfer and gene therapy

M. Pelegrin , M. Marin , D. Noel , Marc Piechaczyk
Human Gene Therapy, 1998, 9 (15), pp.2165--75. ⟨10.1089/hum.1998.9.15-2165⟩
Article dans une revue hal-02195932v1

Antiviral activity of an intracellularly expressed single-chain antibody fragment directed against the murine leukemia virus capsid protein

M. Marin , M. Pelegrin-Zurilla , E. Bachrach , D. Noel , F. Brockly , et al.
Human Gene Therapy, 2000, 11 (3), pp.389--401. ⟨10.1089/10430340050015860⟩
Article dans une revue hal-02196821v1

Efficient cell infection by Moloney murine leukemia virus-derived particles requires minimal amounts of envelope glycoprotein

E. Bachrach , M. Marin , M. Pelegrin , G. Karavanas , Marc Piechaczyk
Journal of Virology, 2000, 74 (18), pp.8480--6. ⟨10.1128/JVI.74.18.8480-8486.2000⟩
Article dans une revue hal-02196806v1

Monoclonal antibody 667 recognizes the variable region a motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor

H. Dreja , L. Gros , Sophie Villard , E. Bachrad , A. Oates , et al.
Journal of Virology, 2003, 77 (20), pp.10984-10993
Article dans une revue hal-02673454v1
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Fc-Dependent Immunomodulation Induced by Antiviral Therapeutic Antibodies: New Perspectives for Eliciting Protective Immune Responses

Mireia Pelegrin , Soledad Marsile-Medun , Daouda Abba-Moussa , Manon Souchard , Mar Naranjo-Gomez
Antibodies, 2022, 11 (3), pp.50. ⟨10.3390/antib11030050⟩
Article dans une revue hal-03750766v1

Efficient gene transfer into spleen cells of newborn mice by a replication-competent retroviral vector

E. Bachrach , M. Pelegrin , Marc Piechaczyk , F. S. Pedersen , M. Duch
Virology, 2002, 293 (2), pp.328--34. ⟨10.1006/viro.2001.1284⟩
Article dans une revue hal-02197485v1

[Vaccine-like effects of antiviral monoclonal antibodies: a novel therapeutic perspective?]

M. Pelegrin , L. Gros , Marc Piechaczyk
Médecine/Sciences, 2013, 29 (5), pp.457--60. ⟨10.1051/medsci/2013295005⟩
Article dans une revue hal-02193670v1

Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells

M. Pelegrin , M. Marin , D. Noel , M. del Río , R. Saller , et al.
Gene Therapy, 1998, 5 (6), pp.828--34. ⟨10.1038/sj.gt.3300632⟩
Article dans une revue hal-02195931v1

Skin as a potential organ for ectopic monoclonal antibody production

D. Noel , J. E. Dazard , M. Pelegrin , C. Jacquet , Marc Piechaczyk
Journal of Investigative Dermatology, 2002, 118 (2), pp.288--94. ⟨10.1046/j.0022-202x.2001.01625.x⟩
Article dans une revue hal-02197504v1

High in vivo production of a model monoclonal antibody on adenoviral gene transfer

D. Noel , M. Pelegrin , S. Kramer , C. Jacquet , N. Skander , et al.
Human Gene Therapy, 2002, 13 (12), pp.1483--1493. ⟨10.1089/10430340260185111⟩
Article dans une revue hal-02197536v1
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Vaccinal effect of HIV-1 antibody therapy: dream or reality?

Mar Naranjo-Gomez , M. Pelegrin
Current Opinion in HIV and AIDS, 2023, Publish Ahead of Print, ⟨10.1097/COH.0000000000000797⟩
Article dans une revue hal-04103262v1

Induction of long-term protective antiviral endogenous immune response by short neutralizing monoclonal antibody treatment

L. Gros , H. Dreja , A. L. Fiser , M. Plays , M. Pelegrin , et al.
Journal of Virology, 2005, 79 (10), pp.6272--80. ⟨10.1128/JVI.79.10.6272-6280.2005⟩
Article dans une revue hal-02262229v1

Efficient mother-to-child transfer of antiretroviral immunity in the context of preclinical monoclonal antibody-based immunotherapy

L. Gros , M. Pelegrin , M. Plays , Marc Piechaczyk
Journal of Virology, 2006, 80 (20), pp.10191--200. ⟨10.1128/JVI.01095-06⟩
Article dans une revue hal-02262462v1

Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor

H. Dreja , L. Gros , S. Villard , E. Bachrach , A. Oates , et al.
Journal of Virology, 2003, 77 (20), pp.10984--93. ⟨10.1128/JVI.77.20.10984-10993.2003⟩
Article dans une revue hal-02199822v1
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The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs

G. Bossis , J. E. Sarry , C. Kifagi , M. Ristic , E. Saland , et al.
Cell Reports, 2014, 7 (6), pp.1815--23. ⟨10.1016/j.celrep.2014.05.016⟩
Article dans une revue hal-02191559v1