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Grafts of olfactory stem cells restore breathing and motor functions after a rat spinal cord injury

Jean-Claude Stamegna , Kevin Sadelli , Guy Escoffier , Stéphane D. Girard , Antoine D. Veron , et al.
Journal of Neurotrauma, 2018, ⟨10.1089/neu.2017.5383⟩
Article dans une revue hal-01718177v1

Use of LDL receptor-targeting peptide vectors for in vitro and in vivo cargo transport across the blood-brain barrier.

Yves Molino , Marion David , Karine Varini , Françoise Jabès , Nicolas Gaudin , et al.
FASEB Journal, 2017
Article dans une revue hal-01478978v1
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Neurotensin receptor 2 is induced in astrocytes and brain endothelial cells in relation to neuroinflammation following pilocarpine‐induced seizures in rats

Grigorios Kyriatzis , Anne Bernard , Angélique Bôle , Guillaume Pflieger , Petros Chalas , et al.
Glia, 2021, 69 (11), pp.2618 - 2643. ⟨10.1002/glia.24062⟩
Article dans une revue hal-03452666v1

Utilisation de dérivés peptidiques (peptides et pseudo-peptides), qui présentent une affinité pour des récepteurs/transporteurs cellulaires, des types cellulaires particuliers et/ou qui passent les membranes cellulaires notamment celles des barrières physiologiques du cerveau telle que la barrière hémato-encéphalique (BHE), comme vecteurs de molécules d'intérêt thérapeutique ou d'agents d'imagerie ou de diagnostic ou de toute autre molécule comme une sonde moléculaire

Michel Khrestchatisky , Société Vect-Horus
N° de brevet: En cours. 2009
Brevet hal-00321258v1

Cholecalciferol (vitamin D-3) improves functional recovery when delivered during the acute phase after a spinal cord trauma

Yatma Gueye , Tanguy Marqueste , Fanny Maurel , Michel Khrestchatisky , Patrick Decherchi , et al.
Journal of Steroid Biochemistry and Molecular Biology, 2015, 154, pp.23-31. ⟨10.1016/j.jsbmb.2015.06.007⟩
Article dans une revue hal-01414098v1
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Neurotensin receptor 2 is induced in astrocytes and brain endothelial cells in relation to status epilepticus and neuroinflammation following pilocarpine administration in rats

Kyriatzis Grigorios , Bernard Anne , Bôle Angélique , Pflieger Guillaume , Chalas Petros , et al.
2020
Pré-publication, Document de travail hal-03073954v1

Target engagement and intracellular delivery of mono- and bivalent LDL receptor-binding peptide-cargo conjugates: Implications for the rational design of new targeted drug therapies

K. Varini , P. Lécorché , R. Sonnette , F. Gassiot , B. Broc , et al.
Journal of Controlled Release, 2019, 314, pp.141-161. ⟨10.1016/j.jconrel.2019.10.033⟩
Article dans une revue hal-02348680v1
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Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal ă cord-derived microvascular endothelial cells

Yves Molino , Francoise Jabes , Amandine Bonnet , Nicolas Gaudin , Anne Bernard , et al.
Journal of Neuroinflammation, 2016, 13 (1), pp.290. ⟨10.1186/s12974-016-0749-6⟩
Article dans une revue hal-01477828v1

Onset of hippocampus-dependent memory impairments in 5XFAD transgenic mouse model of Alzheimer's disease

Stéphane D. Girard , Marlyse Jacquet , Kévin Baranger , Martine Migliorati , Guy Escoffier , et al.
Hippocampus, 2014, 24 (7), pp.762--772. ⟨10.1002/hipo.22267⟩
Article dans une revue istex hal-01718190v1

A unique method for the isolation of nasal olfactory stem cells in living rats

Jean-Claude Stamegna , Stéphane D. Girard , Antoine Veron , Gilles Sicard , Michel Khrestchatisky , et al.
Stem Cell Research, 2014, 12 (3), pp.673--679. ⟨10.1016/j.scr.2014.02.010⟩
Article dans une revue hal-01718191v1

Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein.

M Cardoso , S Timsit , L Villard , Michel Khrestchatisky , M Fontès , et al.
Human Molecular Genetics, 1998, 7 (4), pp.679-84
Article dans une revue hal-02090196v1
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Pilocarpine-Induced Status Epilepticus in the Rat Hippocampus is Associated with Reactive Glia and Concomitant Increased Expression of CD31, PDGFRβ and Collagen IV in Endothelial Cells and Pericytes of the Blood Brain Barrier

Grigorios Kyriatzis , Anne Bernard , Angélique Bôle , Michel Khrestchatisky , Lotfi Ferhat
2023
Pré-publication, Document de travail hal-04301907v1
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Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017

John Greenwood , Margareta Hammarlund-Udenaes , Hazel C. Jones , Alan W. Stitt , Roosmarijn E. Vandenbroucke , et al.
Fluids and Barriers of the CNS, 2018, 15 (1), pp.3. ⟨10.1186/s12987-017-0086-x⟩
Article dans une revue hal-01718178v1
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Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model

Kévin Baranger , Manuel van Gijsel-Bonnello , Delphine Stephan , Wassila Carpentier , Santiago Rivera , et al.
Neurotherapeutics, 2019, ⟨10.1007/s13311-019-00754-z⟩
Article dans une revue hal-02339537v1

Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

Emilie Cornille , Mhamad Abou-Hamdan , Michel Khrestchatisky , André Nieoullon , Max de Reggi , et al.
BMC Neuroscience, 2010, 11, pp.51. ⟨10.1186/1471-2202-11-51⟩
Article dans une revue hal-00848881v1
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Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017

John Greenwood , Margareta Hammarlund-Udenaes , Hazel C. Jones , Alan W. Stitt , Roosmarijn E. Vandenbroucke , et al.
Fluids and Barriers of the CNS, 2017, 14 (1), pp.31. ⟨10.1186/s12987-017-0079-9⟩
Article dans une revue hal-01718184v1
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MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro

Kévin Baranger , Amandine E Bonnet , Stéphane D Girard , Michel Paumier , Laura García-González , et al.
Frontiers in Molecular Neuroscience, 2017, 9, pp.163. ⟨10.3389/fnmol.2016.00163⟩
Article dans une revue hal-01479008v1
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LDLR-mediated targeting and productive uptake of siRNA-peptide ligand conjugates in vitro and in vivo

Broc B , Varini K , Sonnette R , Pecqueux B , Benoist F , et al.
2023
Pré-publication, Document de travail hal-04300755v1

Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8.

Munkeby Bh , Borke Wb , K. Bjornland , Sikkeland Li , Borge Gi , et al.
Pediatric Research, 2005, 58, pp.542-548
Article dans une revue hal-00094385v1

Utilisation de substances modulatrices de l'expression ou de la fonction d'une protéine impliquée dans le cycle cellulaire pour le traitement ou la prévention des lésions neurales aiguës

S. Timsit , P. Cavelier , Y. Ben-Ari , Michel Khrestchatisky , L. Meijer
France, N° de brevet: FR00/03673. 2000
Brevet hal-00095538v1
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Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transport

Yves Molino , Françoise Jabès , Emmanuelle Lacassagne , Nicolas Gaudin , Michel Khrestchatisky
Journal of visualized experiments : JoVE, 2014, 88 (88), pp.e51278. ⟨10.3791/51278⟩
Article dans une revue hal-01718193v1
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The actin binding protein α-actinin-2 expression is associated with dendritic spine plasticity and migrating granule cells in the rat dentate gyrus following pilocarpine-induced seizures

Oualid Sbai , Rabia Soussi , Angélique Bole , Michel Khrestchatisky , Monique Esclapez , et al.
Experimental Neurology, 2021, 335, pp.113512. ⟨10.1016/j.expneurol.2020.113512⟩
Article dans une revue hal-03452685v1

MT5-MMP at the crossroads of neuroinflammation and amyloidogenesis: study in murine and human neural cells

Dominika Pilat , Laura García-González , Jean-Michel Paumier , Laurie Arnaud , Louise Greetham , et al.
Alzheimer's & Parkinson's Diseases Congress (AD/PD), Mar 2021, Barcelone, Spain
Communication dans un congrès hal-03866330v1
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From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells

Stephane Girard , Isabelle Virard , Emmanuelle Lacassagne , Jean-Michel Paumier , Hanae Lahlou , et al.
Stem Cells International, 2017, 2017, 1478606 (17 p.). ⟨10.1155/2017/1478606⟩
Article dans une revue hal-02282115v1
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Isolation and characterization of olfactory ecto-mesenchymal stem cells from eight mammalian genera

Antoine Veron , Cécile Bienboire-Frosini , François Feron , Elisa Codecasa , Arnaud Deveze , et al.
BMC Veterinary Research, 2018, 14 (1), ⟨10.1186/s12917-018-1342-2⟩
Article dans une revue hal-02282096v1
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MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid ă pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease

Kévin Baranger , Yannick Marchalant , Amandine E. Bonnet , Nadine Crouzin , Alex Carrete , et al.
Cellular and Molecular Life Sciences, 2016, 73 (1), pp.217-236. ⟨10.1007/s00018-015-1992-1⟩
Article dans une revue hal-01477822v1
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Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?

Serge Timsit , Santiago Rivera , Philippe Ouaghi , Frédérique Guischard , Evelyne Tremblay , et al.
European Journal of Neuroscience, 1999, 11 (1), pp.263-78
Article dans une revue inserm-00486281v1

Neurotensin and Neurotensin Receptors in Stress-related Disorders: Pathophysiology & Novel Drug Targets

Grigorios Kyriatzis , Michel Khrestchatisky , Lotfi Ferhat , Ekaterini Alexiou Chatzaki
Autre publication scientifique hal-04235699v1

Induction of infertility in adult male bonnet monkeys by immunization with phage-expressed peptides of the extracellular domain of FSH receptor

Michel Khrestchatisky , Rao Aj , Ramachandra Sg , V. Ramesh , L. Abdennebi , et al.
Reproductive BioMedicine Online, 2004, 4, pp.385-391
Article dans une revue hal-00093408v1

Involvement of tissue inhibition of metalloproteinases-1 in learning and memory in mice.

Chaillan Fa , S. Rivera , E. Marchetti , J. Jourquin , Z. Werb , et al.
Behavioural Brain Research, 2006, 173(2), pp.191-198
Article dans une revue hal-00092810v1