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A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat.
Maïte Hotte
,
François Dauphin
,
Thomas Freret
,
Michel Boulouard
,
Guenaëlle Levallet
Article dans une revue
hal-00862771v1
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Comparison of the effects of erythropoietin and its carbamylated derivative on behaviour and hippocampal neurogenesis in mice.
Claire Leconte
,
Ebeline Bihel
,
François-Xavier Lepelletier
,
Valentine Bouët
,
Romaric Saulnier
,
et al.
Article dans une revue
hal-00863054v1
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Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.
Valentine Bouët
,
Thomas Freret
,
Jérôme Toutain
,
Didier Divoux
,
Michel Boulouard
,
et al.
Article dans une revue
istex
hal-00178296v1
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4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.
Michel Boulouard
,
Pascale Schumann-Bard
,
Sabrina Butt-Gueulle
,
Elodie Lohou
,
Silvia Stiebing
,
et al.
Article dans une revue
istex
hal-00864259v1
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Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT 4 R) partial agonist and 5-HT 6 R antagonist activities, as potential treatment of Alzheimer’s disease
Samir Yahiaoui
,
Katia Hamidouche
,
Céline Ballandonne
,
Audrey Davis
,
Jana Sopkova-de Oliveira Santos
,
et al.
Article dans une revue
hal-02043759v1
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Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals
Valentine Bouet
,
Thomas Freret
,
Patrick Dutar
,
Jean-Marie Billard
,
Michel Boulouard
Article dans une revue
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hal-02325196v1
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Long-term functional outcome following transient middle cerebral artery occlusion in the rat: correlation between brain damage and behavioral impairment.
Thomas Freret
,
Laurent Chazalviel
,
Simon Roussel
,
Myriam Bernaudin
,
Pascale Schumann-Bard
,
et al.
Article dans une revue
hal-00865366v1
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Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse.
Virginie da Silva Costa
,
Pascal Duchatelle
,
Michel Boulouard
,
François Dauphin
Article dans une revue
hal-00863265v1
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Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology.
Alban Lepailleur
,
Thomas Freret
,
Stéphane Lemaître
,
Michel Boulouard
,
François Dauphin
,
et al.
Journal of Chemical Information and Modeling, 2014, 54 (6), pp.1773-1784
Article dans une revue
hal-01064770v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride
Cédric Lecoutey
,
Cédric Lecoutey
,
Florence Gaven
,
Patrizia Giannoni
,
Katia Hamidouche
,
et al.
Article dans une revue
hal-02043873v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment
Cédric Lecoutey
,
Damien Hedou
,
Thomas Freret
,
Patrizia Giannoni
,
Florence Gaven
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Article dans une revue
hal-01800439v2
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Chronic ethanol consumption induces tolerance to the spatial memory impairing effects of acute ethanol administration in rats.
Michel Boulouard
,
Véronique Lelong
,
Martine Daoust
,
Mickaël Naassila
Behavioural Brain Research, 2002, 136 (1), pp.239-46
Article dans une revue
inserm-00746180v1
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Serotonin 5-HT6 receptor blockade reverses the age-related deficits of recognition memory and working memory in mice.
Virginie da Silva Costa-Aze
,
François Dauphin
,
Michel Boulouard
Article dans une revue
istex
hal-00862995v1
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A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer’s Disease
Bérénice Hatat
,
Samir Yahiaoui
,
Cédric Lecoutey
,
Audrey Davis
,
Thomas Freret
,
et al.
Article dans une revue
hal-02399864v1
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Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse
Benoît Haelewyn
,
Thomas Freret
,
Emilie Pacary
,
Pascale Schumann-Bard
,
Michel Boulouard
,
et al.
Article dans une revue
istex
hal-00867870v1
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Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.
Thomas Freret
,
Valentine Bouet
,
Claire Leconte
,
Simon Roussel
,
Laurent Chazalviel
,
et al.
Article dans une revue
hal-00863264v1
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Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging
Véronique Paban
,
Jean-Marie Billard
,
Valentine Bouet
,
Thomas Freret
,
Michel Boulouard
,
et al.
Article dans une revue
istex
hal-02325134v1
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Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances
Anne Quiedeville
,
Michel Boulouard
,
Katia Hamidouche
,
Virginie da Silva Costa-Aze
,
Gerald Nee
,
et al.
Article dans une revue
hal-02043824v1
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Donecopride, a Swiss army knife with potential interest against Alzheimer's disease
Christophe Rochais
,
Cédric Lecoutey
,
Katia Hamidouche
,
Patrizia Giannoni
,
Florence Gaven
,
et al.
Article dans une revue
hal-02428730v1
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Psychological impact of the COVID-19 outbreak in community pharmacists: A longitudinal study
Marie Lange
,
Idlir Licaj
,
Michel Boulouard
,
David Garon
,
Estelle Richard
,
et al.
Article dans une revue
hal-04316242v1
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5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice.
Virginie da Silva Costa-Aze
,
Anne Quiedeville
,
Michel Boulouard
,
François Dauphin
Article dans une revue
istex
hal-00862409v1
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Mimicking schizophrenia symptoms in mice by combining factors: genetic, early environmental stress and late pharmacological conditioning
Valentine Bouët
,
Solenn Percelay
,
Nicole Turnbull
,
Thomas Freret
,
Michel Boulouard
NeuroFrance, May 2019, Marseille, France
Poster de conférence
hal-02492831v1
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Deletion of the serotonin receptor type 7 disrupts the acquisition of allocentric but not egocentric navigation strategies in mice
Gregory Beaudet
,
Christelle Jozet-Alves
,
Rachel Asselot
,
Pascale Schumann-Bard
,
Thomas Freret
,
et al.
Article dans une revue
hal-01472663v1
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Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease
François-Xavier Toublet
,
Julien Lalut
,
Bérénice Hatat
,
Cédric Lecoutey
,
Audrey Davis
,
et al.
Article dans une revue
hal-03082877v1
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Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse
Thomas Freret
,
Véronique Lelong-Boulouard
,
Pierre Lecouflet
,
Katia Hamidouche
,
François Dauphin
,
et al.
Article dans une revue
hal-02135214v1
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Combining adverse factors to build a new 3-hit model of schizophrenia
Solenn Percelay
,
Valentine Bouët
,
Thomas Freret
,
Michel Boulouard
XXIIème journées de l'Ecole Doctorale normande de Biologie Intégrétive, Santé, Environnement, Mar 2019, Caen, France. , 2019
Poster de conférence
hal-02135476v1
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Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.
Stéphane Lemaître
,
Alban Lepailleur
,
Ronan Bureau
,
Sabrina Butt-Gueulle
,
Véronique Lelong-Boulouard
,
et al.
Article dans une revue
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hal-00863300v1
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Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.
Thomas Freret
,
Samuel Valable
,
Laurent Chazalviel
,
Romaric Saulnier
,
Eric T Mackenzie
,
et al.
Article dans une revue
istex
hal-00865370v1
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Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
Lydia Danglot
,
Thomas Freret
,
Nicolas Le Roux
,
Nicolas Narboux Nême
,
Andrea Burgo
,
et al.
Article dans une revue
hal-00776396v1
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5-HT7 receptors are strongly implicated in allocentric navigation strategy in mice
Gregory Beaudet
,
Christelle Jozet-Alves
,
Thomas Freret
,
Pascale Schumann-Bard
,
Valentine Bouet
,
et al.
19ème Congrès de la Société Française de Pharmacologie et de Thérapeutique, Apr 2015, Caen, France
Poster de conférence
hal-02436415v1
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