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CV Mélanie Mignot


Academic career:

2019 – present Assistant professor-COBRA laboratory-INSA Rouen, University of Rouen Normandie

2018 – 2019 Postdoctoral Researcher, KU Leuven/ Pharmaceutical Analysis, Belgium (promoter: Prof. D. Cabooter). Title: Chromatographic micro-column development for pharmaceutical applications in zebrafish. Funding: European MSCA grant Project ChromaFish number 799806

2017 – 2018 Postdoctoral Researcher, KU Leuven/ Pharmaceutical Analysis, Belgium (promoter: Prof. D. Cabooter). Title: Development of analytical methodologies for the analysis of surfactant in the tank cleaning sector

2016 – 2017 Temporary Assistant Professor (250 hours), IUT Chemical (half-time) and Physical Measurement (half-time) departments, University of Rouen (France) 

Education:

2013 – 2016 European PhD in Analytical Chemistry, Laboratory of Science and Separation Methods (SMS), University of Rouen, France (promoters: Dr. V. Agasse, Prof. P. Cardinael) Funding: French Research Ministry

2011– 2013 Master in Analytical Chemistry, University of Rouen, France Grade: With honors, Major

Teaching activities:

2019 – present Assistant professor, MRIE & Perf-ISP departments, INSA Rouen Normandie Description: Courses, tutorial classes in analytical chemistry, experimental classes in analytical chemistry and process safety

2016 – 2017 Temporary assistant professor (250 hours), Chemical and Physical departments, IUT, Rouen, France. Description: Tutorial classes in chemistry, experimental classes in chemistry, in chromatography and in spectroscopy

2014 – 2015 Assistant (64 hours), Chemical department, University of Rouen, France Description: Spectroscopy classes (UV-vis, IR), tutorial classes in environmental chemistry, experimental classes in analytical chemistry

Supervision of students/PhD:

2020 - present Supervision of 1 M2, 2 DUT

2019-present Supervision of Monica Gisel Arellano Sanchez, CONACYT grant, Title: Speciation of chromium species by column and planar chromatography coupled to molecular and elemental mass spectrometry

2013 – 2017 Supervision of 17 trainees • 10 Bachelor students, SMS laboratory, University of Rouen, France • 2 Bachelor students in industry : Société Générale de Surveillance (SGS), Saint-Etienne du Rouvray, France and in Sanofi, Saint Aubin-les-Elbeuf, France • 5 Master students, SMS laboratory, University of Rouen, France

Institutional responsibilities:

2020- actual Referee for Sustainable development and societal responsabilities (MRIE department - INSA Rouen Normandie)

2015 – 2016 Elected member of the Scientific Research Commission, University of Rouen, France

2015 – 2016 Elected PhD students’ representative at the laboratory council, University of Rouen, France

Research projects:

2020           AMI RIN 2021 RIN recherche Labels d’Excellence. Obtention of PhD project funding: New methodologies for second and third generation bio-oil characterization. PhD between COBRA Rouen, ISA Lyon starting on October, 2021. 

2018           European MSCA grant (postdoc), ChromaFish project number 799806, KU Leuven/ Pharmaceutical Analysis, Belgium.

Invitations:

2020 Invited member of the PhD defense of Meriem Kajeiou (LOMC) Titre : Épuration des eaux de ruissellement par du bio-adsorbant

2019 Thesis committee of Felix Houtin Mongrolle (CORIA) : Etude numérique de l’interaction de sillages d’éoliennes offshore en dérapage.

2019 Thesis committee of   Ubiera Ruiz Lilivet (LSPC) : Procédés de production de bio-huiles par pyrolyse de la biomasse sous micro-ondes

2019 Thesis committee of Kevin Humbert (COBRA, M2C): Vers une nouvelle méthode de quantification de Contaminants Organiques et Métalliques par imagerie HYperspec 

2018 Scientific day CCVS « Autour de la phase stationnaire ». Titre : Elaboration d'une gamme de phases stationnaires sur silice partiellement poreuses : Quelles modifications de surface pour quelles applications ? Rouen

2018 reviewing for Chemical Engineering Journal (IF 6.216). Title: Degradation behaviors and genetic toxicity variations of pyrazolone pharmaceuticals during chlorine dioxide disinfection process.

2018 Reviewing for Journal of Chromatography, A (IF 3.981). Title: The separations using pure water as mobile phase in liquid chromatography.

 

Employment committee for a position as temporary assistant professor at INSA Rouen 2019 and 2020

Organisation of scientific meetings:

2017 Co-organization of SEP 2017, Paris, Young research section (March 28th-30th)

2016 Co-organization of ESCB1, Rouen, France, August 29th-September 2nd (logistic help)

2016 Chairman of the Young research section of the national days of AFSEP, Orléans, France (June 16th-17th)

2016 Organization of the 9th scientific days of the young section of AFSEP, Rouen, France (April 18th-19th). Role: funding request, goodies request, quotation of food/drink for break and lunch, quotation for USB keys with the AFSEP logo, request the laboratories of my institute to welcome the participants for a presentation of their equipment ...)

2015 Co-organization of the 8th scientific days of the young section of AFSEP, Lyon, France (May 28th-29th)

2015 Co-organization of SEP 2015, Young research section, Paris, France (March 31th-April 2nd) 

Industrial innovation/Academic collaborations:

2013 – 2016 Industrial collaboration, Interchim, Montluçon, France • Elaboration of stationary phases based on core-shell particles (7 columns Uptisphere CS Evolution™ commercialized) • Training session about core-shell particles during the commercial team week, Montluçon • Experimental training of the production staff, Rouen

2013 – 2016 Initiation of academic collaboration with the analysis & modelling unit, University of Rouen, France. Dr. Vincent Tognetti (molecular modelling) and Dr. Muriel Sebban (NMR)

2015 Academic collaboration (1 month internship), Pharmaceutical Chemical Analysis Laboratory (LCAP), University of Geneva, Switzerland (Dr. D. Guillarme and Prof. J.L. Veuthey) 2015 Academic collaboration (2 months internship), Organic Chemistry Laboratory (LCO), University of Brussels, Belgium. Prof. I. Jabin 

Membership of scientific societies:

2019-present Member of AFSEP (French Association of Separative Sciences)

2013 – 2018 Young section of AFSEP Positions: Communication Manager (2015), treasurer (2016), president (2017)

Awards:

2016 Finalist for Consideration of the 2016 Csaba Horváth Young Scientist Award, High Performance Liquid Phase Separations and Related Techniques (HPLC), June, 19-24th , San Francisco, USA

2015 Award of the best scientific presentation- Young researcher days (JNOEJC), May, 11-12th, Rouen, France

2014 Award of the best scientific presentation, VIIth scientific days of the young section of AFSEP, July, 7-8th, Paris, France

 

 

 


Journal articles12 documents

  • Meriem Kajeiou, Abdellah Alem, Soumaya Mezghich, Nasre-Dine Ahfir, Mélanie Mignot, et al.. Competitive and non-competitive zinc, copper and lead biosorption from aqueous solutions onto flax fibers. Chemosphere, Elsevier, 2020, 260, pp.127505. ⟨10.1016/j.chemosphere.2020.127505⟩. ⟨hal-02925748⟩
  • Sven Poelmans, Maarten Nagels, Mélanie Mignot, Raf Dewil, Deirdre Cabooter, et al.. Effect of ozonation as pre-treatment and polishing step on removal of ecotoxicity and alkylphenol ethoxylates from tank truck cleaning wastewater. Journal of Water Process Engineering, Elsevier, 2020, 37, pp.101441. ⟨10.1016/j.jwpe.2020.101441⟩. ⟨hal-02882119⟩
  • P Fotsing, E. Djoufac Woumfo, S Mezghich, M. Mignot, Nadine Mofaddel, et al.. Surface modification of biomaterials based on cocoa shell with improved nitrate and Cr(VI) removal. RSC Advances, Royal Society of Chemistry, 2020, 10, pp.20009-20019. ⟨10.1039/d0ra03027a⟩. ⟨hal-02641027⟩
  • Arianna Giusti, Xuan-Bac Nguyen, Stanislav Kislyuk, Mélanie Mignot, Cecilia Ranieri, et al.. Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos. International Journal of Molecular Sciences, MDPI, 2019, 20 (7), pp.1712. ⟨10.3390/ijms20071712⟩. ⟨hal-02130418⟩
  • Mélanie Mignot, Maarten Nagels, Sven Poelmans, Alexander Kensert, Jan Dries, et al.. Fast liquid chromatography-tandem mass spectrometry methodology for the analysis of alkylphenols and their ethoxylates in wastewater samples from the tank truck cleaning industry. Analytical and Bioanalytical Chemistry, Springer Verlag, 2019, 411 (8), pp.1611-1621. ⟨10.1007/s00216-019-01623-6⟩. ⟨hal-02130423⟩
  • Mélanie Mignot, Clément de Saint Jores, Alain Tchapla, Francois Boyer, Pascal Cardinaël, et al.. New anthracenyl polar embedded stationary phases with enhanced aromatic selectivity, a combined experimental and theoretical study: Part 1-experimental study. Journal of Chromatography A, Elsevier, 2017, 1512, pp.9 - 21. ⟨10.1016/j.chroma.2017.06.065⟩. ⟨hal-01927986⟩
  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Pascal Cardinaël, et al.. Anthracenyl polar embedded stationary phases with enhanced aromatic selectivity. Part II: A density functional theory study. Journal of Chromatography A, Elsevier, 2017, 1519, pp.91-99. ⟨10.1016/j.chroma.2017.08.083⟩. ⟨hal-01928169⟩
  • Antoine Burel, Sander Brugman, Mélanie Mignot, Yohann Cartigny, Séverine Tisse, et al.. Phenanthrene Purification: Comparison of Zone Melting and Co-Crystallization. Chemical Engineering & Technology, 2016, 39 (7), pp.1317-1325. ⟨10.1002/ceat.201600033⟩. ⟨hal-02468108⟩
  • Mélanie Mignot, Aurélie Périat, Valerie Peulon-Agasse, Pascal Cardinaël, Jean-Luc Veuthey, et al.. Evaluation of thermally pretreated silica stationary phases under hydrophilic interaction chromatography conditions. Journal of Separation Science, Wiley-VCH Verlag, 2016, 39 (9), pp.1611 - 1618. ⟨10.1002/jssc.201600034⟩. ⟨hal-01928566⟩
  • Benjamin Schammé, Mélanie Mignot, Nicolas Couvrat, Vincent Tognetti, Laurent Joubert, et al.. Molecular Relaxations in Supercooled Liquid and Glassy States of Amorphous Quinidine: Dielectric Spectroscopy and Density Functional Theory Approaches. Journal of Physical Chemistry B, American Chemical Society, 2016, 120 (30), pp.7579-7592. ⟨10.1021/acs.jpcb.6b04242⟩. ⟨hal-01928417⟩
  • Mélanie Mignot, Muriel Sebban, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, et al.. Thermal pretreatments of superficially porous silica particles for high-performance liquid chromatography: Surface control, structural characterization and chromatographic evaluation. Journal of Chromatography A, Elsevier, 2015, 1419, pp.45-57. ⟨10.1016/j.chroma.2015.09.072⟩. ⟨hal-01929454⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Nicolas Couvrat, Séverine Tisse, et al.. High-Density Octadecyl Chemically Bonded Core–Shell Silica Phases for HPLC: Comparison of Microwave-Assisted and Classical Synthetic Routes, Structural Characterization and Chromatographic Evaluation. Chromatographia, Springer Verlag, 2014, 77 (23-24), pp.1577 - 1588. ⟨10.1007/s10337-014-2802-x⟩. ⟨hal-01929987⟩

Conference papers24 documents

  • W. Nowik, M. Schmitt, M. Mignot, A. Tchapla, Pascal Cardinaël, et al.. Assessment of a new MVP stationary phase for the 2D-RPLC separation of anthraquinone derivatives using descriptors stemmed from Delaunay triangulation. HPLC 2017, Jun 2017, Prague, Czech Republic. ⟨hal-01939199⟩
  • W. Nowik, M. Schmitt, M. Mignot, A. Tchapla, Pascal Cardinaël, et al.. Mise en évidence de l’intérêt d’une nouvelle phase stationnaire (MVP) pour la séparation 2D-RPLC des dérivés d’anthraquinone par évaluation avec différents descripteurs issus de la triangulation de Delaunay. Congrès biennal de l’Association Francophone des Sciences Séparatives, Mar 2017, Paris, France. ⟨hal-01939206⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, Peulon Valérie Agasse. Elaboration d'une gamme de phases stationnaires sur silice partiellement poreuses : quelles modifications de surface pour quelles applications ?. Xèmes journées scientifiques du Club Jeunes de l'AFSEP, Nov 2017, Montpellier, France. ⟨hal-02134227⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, Peulon Valérie Agasse. Vers une meilleure compréhension des propriétés chromatographiques par la modélisation moléculaire : Etude de phases stationnaires aromatiques (mono et trifonctionnelle) à groupement polaire intercalé.. XIIème Congrès de l'Association Francophone des Sciences Séparatives (AFSEP), Mar 2017, Paris, France. ⟨hal-02134226⟩
  • Antoine Burel, Sander Brugman, Mélanie Mignot, Peulon Valérie Agasse, Nicolas Couvrat, et al.. Phenanthrene purification: comparison between Zone Melting and Co-Crystallization. JEEP (Journées des Equilibres Entre Phases) n°42, Mar 2016, Paris, France. ⟨hal-02468869⟩
  • M. Mignot, B. Schammé, V. Tognetti, L. Joubert, A. Tchapla, et al.. New polar-embedded aromatic core-shell stationary phases for high-performance liquid chromatography. HPLC, Jun 2016, San Francisco, United States. ⟨hal-01939615⟩
  • A. Clergé, M. Mignot, Pascal Cardinaël, V. Peulon-Agasse. Synthèse, caractérisation et évaluation chromatographique de phases stationnaires dérivées de calixarène. Journées Nord-Ouest Européennes des Jeunes Chercheurs (JNOEC), Jun 2016, Lille, France. ⟨hal-01939598⟩
  • A. Clergé, M. Mignot, Pascal Cardinaël, V. Peulon-Agasse. Synthesis, Characterisation and Chromatographic Evaluation of Calixarene based Stationary Phases. Journées de l’École Doctorale Normande de Chimie (JEDNC), Jun 2016, Caen, France. ⟨hal-01939604⟩
  • A. Burel, S.J.T. Brugman, M. Mignot, V. Peulon-Agasse, N. Couvrat, et al.. Phenanthrene purification: comparison between zone melting and co-crystallization. 42èmes JEEP, Univ. Paris Descartes, Mar 2016, Paris, France. ⟨hal-01939429⟩
  • A. Clergé, M. Mignot, Pascal Cardinaël, V. Peulon-Agasse. Elaboration de phases stationnaires à base de dérivés de calix[6]arène pour la chromatographie sur microcolonnes. 9ème Journées Scientifiques du Club Jeunes de l’AFSEP, Apr 2016, Rouen, France. ⟨hal-01939460⟩
  • M. Mignot, B. Schammé, V. Tognetti, L. Joubert, A. Tchapla, et al.. New polar-embedded aromatic stationary phases for HPLC. 9ème Journées Scientifiques du Club Jeunes de l’AFSEP, Apr 2016, Rouen, France. ⟨hal-01939462⟩
  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Alain Tchapla, et al.. New insights for the development of polar-embedded aromatic stationary phases. Journées Nord-Ouest Européennes des Jeunes Chercheurs (JNOEJC, 2016), Jun 2016, Lille, France. ⟨hal-02130682⟩
  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Alain Tchapla, et al.. New polar-embedded aromatic stationary phases for HPLC. Journées scientifiques du Club jeunes de l'Association francophone des sciences séparatives (AFSEP, 9, 2016), Apr 2016, Rouen, France. ⟨hal-02130694⟩
  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Alain Tchapla, et al.. Using DFT approaches to investigate the enhanced aromatic selectivity of new antracenyl polar embedded stationary phases for Liquid Chromatography. European symposium on chemical bonding (ESCB, 1, 2016), Aug 2016, Rouen, France. ⟨hal-02130435⟩
  • Mélanie Mignot, Muriel Sebban, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, et al.. Same core-shell silica batch, same microwave grafting procedure leading to various C18 stationary phases? Insight in thermal pretreatments. International Symposium & Exhibit on High Performance Liquid Phase Separations and Related Techniques (HPLC, 44, 2016), Jun 2016, San Francisco (CA), United States. ⟨hal-02130676⟩
  • M. Mignot, Muriel Sebban, A. Tchapla, O. Mercier, Pascal Cardinaël, et al.. How thermal treatments could impact C18 stationary phases made of core-shell particles?. Journées Nord-Ouest Européennes des Jeunes Chercheurs, May 2015, Rouen, France. ⟨hal-01940645⟩
  • M. Mignot, B. Schammé, V. Tognetti, L. Joubert, A. Tchapla, et al.. Microwave preparation, characterization, and evaluation of a new polar-embedded aromatic core-shell stationary phase for high-performance liquid chromatography. HPLC, Jun 2015, Genève, Switzerland. ⟨hal-01940654⟩
  • M. Mignot, Muriel Sebban, A. Tchapla, O. Mercier, Pascal Cardinaël, et al.. Could the same core-shell silica batch functionalized with the same microwave procedure lead to various C18 stationary phases? Insight in thermal pretreatments. HPLC, Jun 2015, Genève, Switzerland. ⟨hal-01940656⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, Valerie Agasse. Microwave preparation, cahracterization, and evaluation of a new polar-embedded aromatic core shell stationary phase for high-performance liquid chromatography. Euroanalysis XVIII, Oct 2015, Bordeaux, France. ⟨hal-01940815⟩
  • Mélanie Mignot, Muriel Sebban, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, et al.. Dans quelle mesure les prétraitements thermiques impactent-ils les phases stationnaires C18 à base de particules de silice partiellement poreuses?. Congrès francophone sur les sciences séparatives et les couplages de l'AFSEP (11, 2015), Mar 2015, Paris, France. ⟨hal-02130690⟩
  • M. Mignot, A. Tchapla, O. Mercier, N. Couvrat, S. Tisse, et al.. Diviser par 10 le temps de fonctionnalisation de particules de silice partiellement poreuses ? Micro-ondes versus chauffage à reflux. 11ème congrès francophone de l’AFSEP sur les Sciences séparatives et les couplages, Mar 2014, Versailles, France. ⟨hal-01940913⟩
  • M. Mignot, A. Tchapla, O. Mercier, N. Couvrat, S. Tisse, et al.. Octadecyl-chemically bonded core-shell silica phases for liquid chromatography: comparison of microwave-assisted and classical synthetic routes, structural characterization and chromatographic evaluation of the stationary phases. Journées Nord-Ouest Européennes des Jeunes Chercheurs, Jun 2014, Lille, France. ⟨hal-01940971⟩
  • M. Mignot, A. Tchapla, O. Mercier, N. Couvrat, S. Tisse, et al.. Core-shell silica particles: Functionalization, characterization, and evaluation of the stationary phases. VIIèmes journées scientifiques du Club Jeunes de l'AFSEP, Jul 2014, Paris, France. ⟨hal-01941040⟩
  • Mélanie Mignot. Rapidité, résolution, efficacité : Apport des particules semi-poreuses en chromatographie. Journées du club de chromatographie, Apr 2014, Rouen, France. ⟨hal-02130710⟩

Poster communications5 documents

  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Alain Tchapla, et al.. New polar-embedded aromatic core-shell stationary phases for high-performance liquid chromatography. International Symposium & Exhibit on High Performance Liquid Phase Separations and Related Techniques (HPLC, 44, 2016), Jun 2016, San Francisco (CA), United States. ⟨hal-02130714⟩
  • Mélanie Mignot, Muriel Sebban, Alain Tchapla, Olivier Mercier, Pascal Cardinaël, et al.. Could the same core-shell silica batch functionalized with the same microwave procedure lead to various C18 stationary phases? Insight in thermalpretreatments. International Symposium on High Performance Liquid Phase Separations & Related Techniques (HPLC, 2015), Jun 2015, Genève, Switzerland. ⟨hal-02130726⟩
  • Mélanie Mignot, Benjamin Schammé, Vincent Tognetti, Laurent Joubert, Alain Tchapla, et al.. Microwave preparation, characterization, and evaluation of a new polarembedded aromatic core-shell stationary phase for high-performance liquid chromatography. International Symposium on High Performance Liquid Phase Separations & Related Techniques (HPLC, 2015), Jun 2015, Genève, Switzerland. ⟨hal-02130722⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Nicolas Couvrat, Séverine Tisse, et al.. Diviser par 10 le temps de fonctionnalisation de particules de silice partiellement poreuses ? Micro-ondes versus chauffage à reflux. 11ème congrès francophone de l’AFSEP sur les Sciences séparatives et les couplages, Mar 2015, Paris, France. ⟨hal-02130730⟩
  • Mélanie Mignot, Alain Tchapla, Olivier Mercier, Nicolas Couvrat, Séverine Tisse, et al.. Core-shell silica particles: Octadecyl silica particles by hydrosilylation and organosilanization. 30th International Symposium on Chromatography (ISC 2014), Sep 2014, Salzburg, Austria. ⟨hal-02130739⟩

Theses1 document

  • Mélanie Mignot. Elaboration de phases stationnaires originales pour la Chromatographie Liquide Haute Performance : Synthèse, caractérisation, et évaluation des propriétés chromatographiques des colonnes.. Chimie analytique. Université de Rouen, France, 2016. Français. ⟨tel-01674550⟩