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Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania

Corinne Asencio , Hervé Perrine , Pauline Morand , Quentin Oliveres , Alexandra Chloé Morel , et al.
2023
Pré-publication, Document de travail hal-04300100v1
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Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function

Denis Dacheux , Guillaume Martinez , Christine Broster Reix , Julie Beurois , Patrick Lorès , et al.
Article dans une revue hal-04241708v1

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

Derrick R Robinson , Mélanie Bonhivers , Sophie Nowacki , Nicolas Landrein , Derrick Robinson
PLoS Biology, 2008, 6 (5), pp.e105. ⟨10.1371/journal.pbio.0060105⟩
Article dans une revue hal-02323437v1
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Yeast two-hybrid interaction assay v1

Mélanie Bonhivers , Anne-Lise Sahin , Nicolas Landrein
2022
Pré-publication, Document de travail hal-03880954v1
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Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei

Anna Albisetti , Célia Florimond , Nicolas Landrein , Keni Vidilaseris , Marie Eggenspieler , et al.
PLoS Pathogens, 2017, 13 (11), pp.e1006710. ⟨10.1371/journal.ppat.1006710⟩
Article dans une revue hal-02482619v1

Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei.

Sabrina Absalon , Thierry Blisnick , Mélanie Bonhivers , Linda Kohl , Nadège Cayet , et al.
Journal of Cell Science, 2008, 121 (Pt 22), pp.3704-16. ⟨10.1242/jcs.035626⟩
Article dans une revue hal-00426339v1
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Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar

Charlotte Isch , Paul Majneri , Nicolas Landrein , Yulia Pivovarova , Johannes Lesigang , et al.
PLoS Pathogens, 2021, 17 (8), pp.e1009329. ⟨10.1371/journal.ppat.1009329⟩
Article dans une revue hal-03324143v1

BILBO1 Is a Scaffold Protein of the Flagellar Pocket Collar in the Pathogen Trypanosoma brucei

Derrick R Robinson , Célia Florimond , Annelise Sahin , Keni Vidilaseris , Gang Dong , et al.
PLoS Pathogens, 2015, 11 (3), pp.e1004654. ⟨10.1371/journal.ppat.1004654⟩
Article dans une revue hal-02322684v1

Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse

Frederick Dong , Amir Amiri-Yekta , Guillaume Martinez , Antoine Saut , Julie Tek , et al.
American Journal of Human Genetics, 2018, 102 (4), pp.636 - 648. ⟨10.1016/j.ajhg.2018.03.007⟩
Article dans une revue hal-01877985v1

Whole-exome sequencing identifies mutations in FSIP2 as a recurrent cause of multiple morphological abnormalities of the sperm flagella

Guillaume Martinez , Zine-Eddine Kherraf , Raoudha Zouari , Selima Fourati Ben Mustapha , Antoine Saut , et al.
Human Reproduction, 2018, 33 (10), pp.1973 - 1984. ⟨10.1093/humrep/dey264⟩
Article dans une revue hal-01877993v1
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Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei

Emma Stepinac , Nicolas Landrein , Daria Skwarzyńska , Patrycja Wójcik , Johannes Lesigang , et al.
iScience, 2021, 24 (5), pp.102422. ⟨10.1016/j.isci.2021.102422⟩
Article dans une revue hal-03246407v1
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Bhalin, an essential cytoskeleton-associated protein of $Trypanosoma\ brucei$ linking TbBILBO1 of the flagellar pocket collar with the hook complex

Christine E. Broster Reix , Célia Florimond , Anne Cayrel , Amélie Mailhé , Corentin Agnero-Rigot , et al.
Microorganisms, 2021, 9 (11), pp.2334. ⟨10.3390/microorganisms9112334⟩
Article dans une revue hal-03475266v1
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TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei

Doranda Perdomo , Elodie Berdance , Gertrud Lallinger-Kube , Annelise Sahin , Denis Dacheux , et al.
Parasite, 2022, 29, pp.14. ⟨10.1051/parasite/2022015⟩
Article dans une revue hal-03611291v1
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TFK1, a basal body transition fibre protein that is essential for cytokinesis in Trypanosoma brucei

Miharisoa Rijatiana Ramanantsalama , Nicolas Landrein , Elina Casas , Bénédicte Salin , Corinne Blancard , et al.
Journal of Cell Science, 2022, 135 (11), pp.jcs259893. ⟨10.1242/jcs.259893⟩
Article dans une revue hal-03817184v1
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Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility

Guillaume Martinez , Julie Beurois , Denis Dacheux , Caroline Cazin , Marie Bidart , et al.
Journal of Medical Genetics, 2020, 57 (10), pp.708-716. ⟨10.1136/jmedgenet-2019-106775⟩
Article dans une revue hal-03004959v1
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Ultra Expansion microscopy protocol with improved setup for upright and inverted microscopes. v1

Elina Casas , Nicolas Landrein , Mélanie Bonhivers
2023
Pré-publication, Document de travail hal-03880908v1

A MAP6-Related Protein Is Present in Protozoa and Is Involved in Flagellum Motility

Derrick R Robinson , Denis Dacheux , Nicolas Landrein , Magali Thonnus , Guillaume Gilbert , et al.
PLoS ONE, 2012, 7 (2), pp.e31344. ⟨10.1371/journal.pone.0031344⟩
Article dans une revue hal-02323247v1
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Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia

Patrick Lorès , Charles Coutton , Elma El Khouri , Laurence Stouvenel , Maelle Givelet , et al.
Human Molecular Genetics, 2018, 27 (7), pp.1196-1211. ⟨10.1093/hmg/ddy034⟩
Article dans une revue hal-02346745v1

The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein—TbBILBO1

Derrick R Robinson , Doranda Perdomo , Mélanie Bonhivers , Derrick Robinson
Cells, 2016, 5 (1), pp.9. ⟨10.3390/cells5010009⟩
Article dans une revue hal-02322589v1
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Basal body positioning is controlled by flagellum formation in Trypanosoma brucei.

Sabrina Absalon , Linda Kohl , Carole Branche , Thierry Blisnick , Géraldine Toutirais , et al.
PLoS ONE, 2007, 2, pp.e437. ⟨10.1371/journal.pone.0000437⟩
Article dans une revue pasteur-00169134v1
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Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding

Keni Vidilaseris , Nicolas Landrein , Yulia Pivovarova , Johannes Lesigang , Niran Aeksiri , et al.
Journal of Biological Chemistry, 2020, 295 (6), pp.1489-1499. ⟨10.1074/jbc.RA119.010768⟩
Article dans une revue hal-03052690v1
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Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding

Keni Vidilaseris , Nicolas Landrein , Yulia Pivovarova , Johannes Lesigang , Niran Aeksiri , et al.
Journal of Biological Chemistry, 2020, 295 (6), pp.1489-1499. ⟨10.1074/jbc.RA119.010768⟩
Article dans une revue hal-02482599v1

A monoclonal antibody marker for the exclusion-zone filaments of Trypanosoma brucei.

Melanie Bonhivers , Nicolas Landrein , Marion Decossas , Derrick Robinson
Parasites & Vectors, 2008, 1 (1), pp.21. ⟨10.1186/1756-3305-1-21⟩
Article dans une revue hal-00300511v1

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in $Trypanosoma$ and human.

Charles Coutton , Alexandra S. Vargas , Amir Amiri-Yekta , Zine-Eddine Kherraf , Selima Fourati Ben Mustapha , et al.
Nature Communications, 2018, 9, pp.686. ⟨10.1038/s41467-017-02792-7⟩
Article dans une revue hal-01724640v1
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Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility

Patrick Lorès , Denis Dacheux , Zine-Eddine Kherraf , Jean-Fabrice Nsota Mbango , Charles Coutton , et al.
American Journal of Human Genetics, 2019, ⟨10.1016/j.ajhg.2019.10.007⟩
Article dans une revue hal-02370384v1

Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated.

Mélanie Bonhivers , Sophie Nowacki , Nicolas Landrein , Derrick R Robinson
PLoS Biology, 2008, 6 (5), pp.e105. ⟨10.1371/journal.pbio.0060105⟩
Article dans une revue hal-00318588v1

NIMA-related kinase TbNRKC is involved in basal body separation in Trypanosoma brucei.

Lydie C Pradel , Mélanie Bonhivers , Nicolas Landrein , Derrick R Robinson
Journal of Cell Science, 2006, 119 (Pt 9), pp.1852-63. ⟨10.1242/jcs.02900⟩
Article dans une revue hal-00215921v1

Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide‐induced maturation and activation of human monocyte‐derived dendritic cells

Frédéric-Antoine Dauchy , Cécile Contin-Bordes , Romaric Nzoumbou-Boko , Melanie Bonhivers , Nicolas Landrein , et al.
Parasite Immunology, 2019, 41 (8), pp.e12632. ⟨10.1111/pim.12632⟩
Article dans une revue hal-02370509v1

A monoclonal antibody marker for the exclusion-zone filaments of Trypanosoma brucei

Derrick R Robinson , Mélanie Bonhivers , Nicolas Landrein , Marion Decossas , Derrick Robinson
Parasites & Vectors, 2008, 1 (1), pp.21. ⟨10.1186/1756-3305-1-21⟩
Article dans une revue hal-02323400v1
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Intrabody induced cell death by targeting the T. brucei cytoskeletal protein TbBILBO1

Christine E Broster Reix , Miharisoa Rijatiana Ramanantsalama , Carmelo Di Primo , Laëtitia Minder , Melanie Bonhivers , et al.
Microbiology Spectrum, 2021, 9 (2), pp.e00915-21. ⟨10.1128/Spectrum.00915-21⟩
Article dans une revue hal-03367221v2