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CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity

 Madison Adolph , Atharv Garje , Swati Balakrishnan , Florian Morati , Mauro Modesti , et al.
Journal of Molecular Biology, 2023, 435 (19), pp.168236. ⟨10.1016/j.jmb.2023.168236⟩
Article dans une revue hal-04275279v1
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Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination

 Ineke Brouwer , Hongshan Zhang , Andrea Candelli , Davide Normanno , Erwin J G Peterman , et al.
Cell Reports, 2017, 18, pp.2845 - 2853. ⟨10.1016/j.celrep.2017.02.068⟩
Article dans une revue hal-01495423v1

Human RPA activates BLM’s bidirectional DNA unwinding from a nick

 Zhenheng Qin , Lulu Bi , Xi-Miao Hou , Siqi Zhang , Xia Zhang , et al.
eLife, 2020, 9, ⟨10.7554/eLife.54098⟩
Article dans une revue hal-03038384v1
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The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition

 Lulu Bi , Zhenheng Qin , Teng Wang , Yanan Li , Xinshuo Jia , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), ⟨10.1073/pnas.2116462119⟩
Article dans une revue hal-03874779v1
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Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface

 Grégory Menchon , Oriane Bombarde , Mansi Trivedi , Aurélie Négrel , Cyril Inard , et al.
Scientific Reports, 2015, 6, pp.22878. ⟨10.1038/srep22878⟩
Article dans une revue hal-01456277v1

CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity

 Madison Adolph , Atharv Garje , Swati Balakrishnan , Florian Morati , Mauro Modesti , et al.
Journal of Molecular Biology, 2023, 435 (19), pp.168236. ⟨10.1016/j.jmb.2023.168236⟩
Article dans une revue hal-04267166v1

Experimental phase diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence

 Mauro Modesti
Nanoscale, 2015, ⟨10.1039/C4NR04332D⟩
Article dans une revue hal-01456283v1

RADX controls RAD51 filament dynamics to regulate replication fork stability

 Mauro Modesti , Madison Adolph , Taha Mohamed , Swati Balakrishnan , Chaoyou Xue , et al.
Molecular Cell, 2021, 81 (5), pp.1074-1083.e5. ⟨10.1016/j.molcel.2020.12.036⟩
Article dans une revue hal-03438611v1

Fluorescent Labeling of Proteins

 Mauro Modesti
X, pp.115-134, 2018
Chapitre d'ouvrage hal-02144111v1
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Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

 Robin Öz , Jing Wang , Raphael Guerois , Gaurav Goyal , Sriram Kk , et al.
Nucleic Acids Research, 2021, 49 (5), pp.2629-2641. ⟨10.1093/nar/gkab083⟩
Article dans une revue hal-03438620v1
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The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity

 Karl-Heinz Tomaszowski , Dorthe Aasland , Geoffrey P Margison , Emma P Williams , Sarah P Pinder , et al.
DNA Repair, 2015, 28, pp.14-20. ⟨10.1016/j.dnarep.2015.01.009⟩
Article dans une revue hal-01456259v1

Simultaneous Mechanical and Fluorescence Detection of Helicase-Catalyzed DNA Unwinding

 Lulu Bi , Zhenheng Qin , Xi-Miao Hou , Mauro Modesti , Bo Sun
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Chapitre d'ouvrage hal-03874145v1
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RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA

 Nicole Kaminski , Anne Wondisford , Youngho Kwon , Michelle Lee Lynskey , Ragini Bhargava , et al.
Molecular Cell, 2022, S1097-2765 (22), pp.00935-2. ⟨10.1016/j.molcel.2022.09.025⟩
Article dans une revue inserm-03825785v1

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

 Jonathan Barroso-González , Laura García-Expósito , Song My Hoang , Michelle Lynskey , Justin Roncaioli , et al.
Molecular Cell, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Article dans une revue hal-02383646v1

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

 Jonathan Barroso-González , Laura García-Expósito , Song My Hoang , Michelle Lynskey , Justin Roncaioli , et al.
Molecular Cell, 2019, 76 (1), pp.217. ⟨10.1016/j.molcel.2019.08.009⟩
Article dans une revue hal-02504773v1

Homologous recombination–deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants

 Rohit Prakash , Yashpal Rawal , Meghan Sullivan , Mckenzie Grundy , Hélène Bret , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (38), pp.e2202727119. ⟨10.1073/pnas.2202727119⟩
Article dans une revue inserm-03812808v1
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Plugged into the Ku-DNA hub: The NHEJ network

 Philippe Frit , Virginie Ropars , Mauro Modesti , Jean-Baptiste Charbonnier , Patrick Calsou
Progress in Biophysics and Molecular Biology, 2019, 147, pp.62-76. ⟨10.1016/j.pbiomolbio.2019.03.001⟩
Article dans une revue hal-02144114v1

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

 Mauro Modesti , Marie Chansel-da Cruz , Marcel Hohl , Ilaria Ceppi , Laëtitia Kermasson , et al.
Cell Reports, 2020, 33 (13), pp.108559. ⟨10.1016/j.celrep.2020.108559⟩
Article dans une revue hal-03438613v1
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Insights into the control of RAD51 nucleoprotein filament dynamics from single-molecule studies

 Florian Morati , Mauro Modesti
Current Opinion in Genetics and Development, 2021, 71, pp.182 - 187. ⟨10.1016/j.gde.2021.09.001⟩
Article dans une revue hal-03874768v1
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Catalytically inactive DNA ligase IV promotes DNA repair in living cells

 Noah Goff , Manon Brenière , Christopher Buehl , Abinadabe de Melo , Hana Huskova , et al.
Nucleic Acids Research, 2022, pp.gkac913. ⟨10.1093/nar/gkac913⟩
Article dans une revue inserm-03825783v1
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XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation

 Sunetra Roy , Abinadabe J de Melo , Yao Xu , Satish K Tadi , Aurélie Négrel , et al.
Molecular and Cellular Biology, 2015, 35 (17), pp.3017-3028. ⟨10.1128/MCB.01503-14⟩
Article dans une revue hal-01456279v1
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XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

 Clément Nemoz , Virginie Ropars , Philippe Frit , Amandine Gontier , Pascal Drevet , et al.
Nature Structural and Molecular Biology, 2018, 25 (10), pp.971-980. ⟨10.1038/s41594-018-0133-6⟩
Article dans une revue hal-02143568v1

BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC)

 Audrey Benyamine , Céline Loncle , Etienne D Foucher , Juan-Luis Blazquez , Céline Castanier , et al.
OncoImmunology, 2017, 7 (1), pp.e1372080. ⟨10.1080/2162402X.2017.1372080⟩
Article dans une revue hal-02383647v1

A basal-level activity of ATR links replication fork surveillance and stress response

 Yandong Yin , Wei Ting Chelsea Lee , Dipika Gupta , Huijun Xue , Peter Tonzi , et al.
Molecular Cell, 2021, 81 (20), pp.4243-4257.e6. ⟨10.1016/j.molcel.2021.08.009⟩
Article dans une revue hal-03874134v1

Simultaneous Mechanical and Fluorescence Detection of Helicase-Catalyzed DNA Unwinding

 Lulu Bi , Zhenheng Qin , Xi-Miao Hou , Mauro Modesti , Bo Sun
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Chapitre d'ouvrage inserm-03825784v1

Insights into the control of RAD51 nucleoprotein filament dynamics from single-molecule studies

 Florian Morati , Mauro Modesti
Current Opinion in Genetics and Development, 2021, 71, pp.182-187. ⟨10.1016/j.gde.2021.09.001⟩
Article dans une revue hal-03874129v1

Simultaneous Mechanical and Fluorescence Detection of Helicase-Catalyzed DNA Unwinding

 Lulu Bi , Zhenheng Qin , Xi-Miao Hou , Mauro Modesti , Bo Sun
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Chapitre d'ouvrage hal-03874960v1

Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

 Ineke Brouwer , Gerrit Sitters , Andrea Candelli , Stephanie J. Heerema , Iddo Heller , et al.
Nature, 2016, 535 (7613), pp.566 - 569. ⟨10.1038/nature18643⟩
Article dans une revue inserm-01403869v1

Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

 Mauro Modesti , Rohit Prakash , Thomas Sandoval , Florian Morati , Jennifer Zagelbaum , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-24205-6⟩
Article dans une revue hal-03438617v1
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Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling

 Wei Ting C. Lee , Yandong Yin , Michael Morten , Peter Tonzi , Pam Pam Gwo , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-22830-9⟩
Article dans une revue hal-03438622v1
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