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The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

Md. hasan Zaki , Peter Vogel , R.K. subbarao Malireddi , Mathilde Body-Malapel , Paras k. Anand , et al.
Cancer Cell, 2011, 20 (5), pp.649 - 660. ⟨10.1016/j.ccr.2011.10.022⟩
Article dans une revue hal-01936352v1
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Review article: epidemiological and animal evidence for the role of air pollution in intestinal diseases

Cécile Vignal , Eva Guilloteau , Corinne Gower , Mathilde Body-Malapel
Science of the Total Environment, 2020, The Science of the total environment, 757, pp.143718. ⟨10.1016/j.scitotenv.2020.143718⟩
Article dans une revue hal-03344188v1

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis

Aurélien Tourteau , Virginie Andrzejak , Mathilde Body-Malapel , Lucas Lemaire , Amélie Lemoine , et al.
Bioorganic and Medicinal Chemistry, 2013, 21 (17), pp.5383 - 5394. ⟨10.1016/j.bmc.2013.06.010⟩
Article dans une revue hal-01935812v1

Switching cannabinoid response from CB2 agonists to FAAH inhibitors

Aurélien Tourteau , Natascha Leleu-Chavain , Mathilde Body-Malapel , Virginie Andrzejak , Amelie Barczyk , et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (5), pp.1322 - 1326. ⟨10.1016/j.bmcl.2014.01.056⟩
Article dans une revue hal-01935807v1

Perception des risques liés à la pollution atmosphérique et modifications des symptômes chez des patients atteints de la maladie de Crohn

Séverine Frère , Isabelle Ducret , Mathilde Body-Malapel , Anne-Peggy Hellequin , Nathalie Guillon , et al.
JFHOD 2019 - Journées Francophones d'Hépato-gastroentérologie et d'Oncologie Digestive, Mar 2019, Paris, France
Poster de conférence hal-04194026v1
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The RAGE signaling pathway is involved in intestinal inflammation and represents a promising therapeutic target for Inflammatory Bowel Diseases.

Mathilde Body-Malapel , Madjid Djouina , Christophe Waxin , Audrey Langlois , Corinne Gower , et al.
Mucosal Immunology, 2018, 12, pp.468-478. ⟨10.1038/s41385-018-0119-z⟩
Article dans une revue hal-02149337v2

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Luigi Franchi , Amal Amer , Mathilde Body-Malapel , Thirumala-Devi Kanneganti , Nesrin Ozören , et al.
Nature Immunology, 2006, 7 (6), pp.576 - 582. ⟨10.1038/ni1346⟩
Article dans une revue istex hal-01936392v1
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Does oral exposure to cadmium and lead mediate susceptibility to colitis? The dark-and-bright sides of heavy metals in gut ecology

Jérôme Breton , Catherine Daniel , Cécile Vignal , Mathilde Body-Malapel , Anne Garat , et al.
Scientific Reports, 2016, Scientific Reports, 6, ⟨10.1038/srep19200⟩
Article dans une revue hal-01935794v2

Toxicological consequences of experimental exposure to aluminum in human intestinal epithelial cells

Madjid Djouina , N Esquerre , Pierre Desreumaux , Cécile Vignal , Mathilde Body-Malapel
Food and Chemical Toxicology, 2016, Food and Chemical Toxicology, 91, pp.108-116. ⟨10.1016/j.fct.2016.03.008⟩
Article dans une revue hal-01935784v1

Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

Thirumala-Devi Kanneganti , Mathilde Body-Malapel , Amal Amer , Jong-Hwan Park , Joel Whitfield , et al.
Journal of Biological Chemistry, 2006, 281 (48), pp.36560 - 36568. ⟨10.1074/jbc.M607594200⟩
Article dans une revue hal-01936385v1
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The Toxic Effects of Xenobiotics on the Health of Humans and Animals

Yanzhu Zhu , Alex Boye , Mathilde Body-Malapel , Jorge Herkovits
BioMed Research International , 2017, 2017, pp.4627872. ⟨10.1155/2017/4627872⟩
Article dans une revue hal-01935782v1

NOD2: a potential target for regulating liver injury.

Mathilde Body-Malapel , Sébastien Dharancy , Dominique Berrebi , Alexandre Louvet , Jean-Pierre Hugot , et al.
Laboratory Investigation, 2008, 88 (3), pp.318-27. ⟨10.1038/labinvest.3700716⟩
Article dans une revue hal-00319070v1

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes.

Nesrin Ozören , Junya Masumoto , Luigi Franchi , Thirumala-Devi Kanneganti , Mathilde Body-Malapel , et al.
Journal of Immunology, 2006, pp.4337-42
Article dans une revue hal-01936397v1

RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs.

Jong-Hwan Park , Yun-Gi Kim , Christine Mcdonald , Thirumala-Devi Kanneganti , Mizuho Hasegawa , et al.
Journal of Immunology, 2007, pp.2380-6
Article dans une revue hal-01936382v1

Conformational Restriction Leading to a Selective CB 2 Cannabinoid Receptor Agonist Orally Active Against Colitis

Jamal El Bakali , Giulio G. Muccioli , Mathilde Body-Malapel , Madjid Djouina , Frédérique Klupsch , et al.
ACS Medicinal Chemistry Letters, 2015, 6 (2), pp.198 - 203. ⟨10.1021/ml500439x⟩
Article dans une revue hal-01935803v1

Gut: An underestimated target organ for Aluminum.

Cécile Vignal , Pierre Desreumaux , Mathilde Body-Malapel
Morphologie, 2016, Morphologie, 100, pp.75-84. ⟨10.1016/j.morpho.2016.01.003⟩
Article dans une revue hal-01935789v1

Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice

Cécile Vignal , Madjid Djouina , Muriel Pichavant , Ségolène Caboche , Christophe Waxin , et al.
Archives of Toxicology, 2018, 92 (7), pp.2327 - 2338. ⟨10.1007/s00204-018-2228-6⟩
Article dans une revue hal-01935763v1
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Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties.

Natascha Leleu-Chavain , Davy Baudelet , Valéria Moas Heloire , Diana Escalante Rocha , Nicolas Renault , et al.
European Journal of Medicinal Chemistry, 2019, 165, pp.347-362. ⟨10.1016/j.ejmech.2018.12.008⟩
Article dans une revue hal-02149143v1

4-Oxo-1,4-dihydropyridines as Selective CB 2 Cannabinoid Receptor Ligands Part 2: Discovery of New Agonists Endowed with Protective Effect Against Experimental Colitis

Jamal El Bakali , Pauline Gilleron , Mathilde Body-Malapel , Roxane Mansouri , Giulio G. Muccioli , et al.
Journal of Medicinal Chemistry, 2012, 55 (20), pp.8948 - 8952. ⟨10.1021/jm3008568⟩
Article dans une revue hal-01935815v1

Recent advances in the development of selective CB(2) agonists as promising anti-inflammatory agents.

R Leleu-Chavain , Mathilde Body-Malapel , J Spencer , P Chavatte , P. Desreumaux , et al.
Current Medicinal Chemistry, 2018, pp.3457-74
Article dans une revue hal-01936350v1

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Thirumala-Devi Kanneganti , Nesrin Özören , Mathilde Body-Malapel , Amal Amer , Jong-Hwan Park , et al.
Nature, 2006, 440 (7081), pp.233 - 236. ⟨10.1038/nature04517⟩
Article dans une revue hal-01936406v1

Nucleotide-binding Oligomerization Domain-1 and Epidermal Growth Factor Receptor

Parjeet Boughan , Richard Argent , Mathilde Body-Malapel , Jong-Hwan Park , Katie Ewings , et al.
Journal of Biological Chemistry, 2006, 281 (17), pp.11637 - 11648. ⟨10.1074/jbc.M510275200⟩
Article dans une revue hal-01936410v1
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Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice.

Madjid Djouina , Christophe Waxin , Segolene Caboche , Karine Lecointe , A. Steimle , et al.
Science of The Total Environment, 2023, Sci Total Environ, 900, pp.165722. ⟨10.1016/j.scitotenv.2023.165722⟩
Article dans une revue hal-04443870v1
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O-GlcNAcylation Links Nutrition to the Epigenetic Downregulation of UNC5A during Colon Carcinogenesis

Amelie Decourcelle , Ninon Very , Madjid Djouina , Ingrid Loison , Julien Thevenet , et al.
Cancers, 2020, Cancers, 12 (11), pp.3168. ⟨10.3390/cancers12113168⟩
Article dans une revue hal-03110218v1

IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation

M. Zaki , P. Vogel , Mathilde Body-Malapel , M. Lamkanfi , T.-D. Kanneganti
Journal of Immunology, 2010, 185 (8), pp.4912 - 4920. ⟨10.4049/jimmunol.1002046⟩
Article dans une revue hal-01936363v1

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis

Virginie Andrzejak , Giulio G. Muccioli , Mathilde Body-Malapel , Jamal El Bakali , Madjid Djouina , et al.
Bioorganic and Medicinal Chemistry, 2011, 19 (12), pp.3777 - 3786. ⟨10.1016/j.bmc.2011.04.057⟩
Article dans une revue hal-01936354v1
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Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature

Nell Hirt , Mathilde Body-Malapel
Particle and Fibre Toxicology, 2020, 17 (1), ⟨10.1186/s12989-020-00387-7⟩
Article dans une revue hal-03007189v2
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Oral exposure to polyethylene microplastics induces inflammatory and metabolic changes and promotes fibrosis in mouse liver.

Madjid Djouina , Christophe Waxin , Laurent Dubuquoy , David Launay , Cecile Vignal , et al.
Ecotoxicology and Environmental Safety, 2023, Ecotoxicology and Environmental Safety, 264, pp.115417. ⟨10.1016/j.ecoenv.2023.115417⟩
Article dans une revue hal-04495402v1

Neutrophil Migration During Liver Injury Is Under Nucleotide-Binding Oligomerization Domain 1 Control

Sébastien Dharancy , Mathilde Body-Malapel , Alexandre Louvet , Dominique Berrebi , Emilie Gantier , et al.
Gastroenterology, 2010, 138 (4), pp.1546 - 1556.e5. ⟨10.1053/j.gastro.2009.12.008⟩
Article dans une revue hal-01936365v1

Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

Amal Amer , Luigi Franchi , Thirumala-Devi Kanneganti , Mathilde Body-Malapel , Nesrin Ozören , et al.
Journal of Biological Chemistry, 2006, 281 (46), pp.35217 - 35223. ⟨10.1074/jbc.M604933200⟩
Article dans une revue hal-01936389v1