CV Maryline Beyler

Laura Abad Galán, Nadege Hamon, Christophe Nguyen, Eniko Molnar, János Kiss, et al.. Design of polyazamacrocyclic Gd3+ theranostic agents combining magnetic resonance imaging and two-photon photodynamic therapy. Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2021, ⟨10.1039/D0QI01519A⟩. ⟨hal-03137794⟩

Gwladys Nizou, Enikő Molnár, Nadège Hamon, Ferenc Krisztián Kálmán, Olivier Fougère, et al.. Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Gadolinium Complexation. Inorganic Chemistry, American Chemical Society, 2021, ⟨10.1021/acs.inorgchem.0c03277⟩. ⟨hal-03122227⟩

Nadège Hamon, Amandine Roux, Maryline Beyler, Jean-Christophe Mulatier, Chantal Andraud, et al.. Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications. Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩. ⟨hal-02616978⟩

Agustín Esteban-Muriel, Carlos Laglera-Gándara, Marta Mato-Iglesias, Raphaël Tripier, Maryline Beyler, et al.. A different approach: highly encapsulating macrocycles being used as organic tectons in the building of CPs. CrystEngComm, Royal Society of Chemistry, 2020, ⟨10.1039/D0CE01499K⟩. ⟨hal-03053378⟩

Laura Grenier, Maryline Beyler, Taunia Closson, Nick Zabinyakov, Alexandre Bouzekri, et al.. Enabling Indium Channels for Mass Cytometry by Using Reinforced Cyclam-Based Chelating Polylysine. Bioconjugate Chemistry, American Chemical Society, In press, ⟨10.1021/acs.bioconjchem.0c00267⟩. ⟨hal-02925847⟩

Jonathan Mendy, Anh Thy Bui, Amandine Roux, Jean-Christophe Mulatier, Damien Curton, et al.. Cationic Biphotonic Lanthanide Luminescent Bioprobes Based on Functionalized Cross‐Bridged Cyclam Macrocycles.. ChemPhysChem, Wiley-VCH Verlag, 2020, 21 (10), pp.1036-1043. ⟨10.1002/cphc.202000085⟩. ⟨hal-02533027⟩

Amaury Guillou, Margaux Galland, Amandine Roux, Balázs Váradi, Réka Gogolák, et al.. Picolinate-Appended Tacn Complexes for Bimodal Imaging: radiolabeling, relaxivity, photophysical and electrochemical studies. Journal of Inorganic Biochemistry, Elsevier, 2019, Epub ahead of print. ⟨10.1016/j.jinorgbio.2019.110978⟩. ⟨inserm-02436868⟩

Laura Grenier, Maryline Beyler, Carlos Platas-Iglesias, Taunia Closson, David Esteban Gómez, et al.. Highly stable and inert complexation of Indium(III) by reinforced cyclam dipicolinate and a bifunctional derivative for bead encoding in mass cytometry. Chemistry - A European Journal, Wiley-VCH Verlag, 2019, ⟨10.1002/chem.201903969⟩. ⟨hal-02281241⟩

Amandine Conte-Daban, Maryline Beyler, Raphaël Tripier, Christelle Hureau. Kinetics are crucial when targeting copper ions to fight Alzheimer's disease: an illustration with azamacrocyclic ligands. Chemistry - A European Journal, Wiley-VCH Verlag, 2018, 24 (33), pp.8447-8452. ⟨10.1002/chem.201801520⟩. ⟨hal-01764900⟩

Mariane Le Fur, Eniko Molnar, Maryline Beyler, Ferenc Kalman, Olivier Fougère, et al.. A Coordination Chemistry Approach to Fine-Tune the Physicochemical Parameters of Lanthanide Complexes Relevant to Medical Applications. Chemistry - A European Journal, Wiley-VCH Verlag, 2018, Chemistry, an European journal, 24 (13), pp.3127-3131. ⟨10.1002/chem.201705528⟩. ⟨hal-01665222⟩

Mariane Le Fur, Enikő Molnár, Maryline Beyler, Olivier Fougere, David Esteban-Gomez, et al.. Expanding the Family of Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Lanthanide Complexation. Inorganic Chemistry, American Chemical Society, 2018, ⟨10.1021/acs.inorgchem.8b00598⟩. ⟨hal-01803853⟩

Mariane Le Fur, Maryline Beyler, Enikő Molnár, Olivier Fougere, David Esteban-Gómez, et al.. Stable and Inert Yttrium(III) Complexes with Pyclen-Based Ligands Bearing Pendant Picolinate Arms: Toward New Pharmaceuticals for β-Radiotherapy. Inorganic Chemistry, American Chemical Society, 2018, 57 (4), pp.2051-2063. ⟨10.1021/acs.inorgchem.7b02953⟩. ⟨hal-01701694⟩

Nadège Hamon, Margaux Galland, Mariane Le Fur, Amandine Roux, Alain Duperray, et al.. Combining a pyclen framework with conjugated antenna for the design of europium and samarium luminescent bioprobes. Chemical Communications, Royal Society of Chemistry, 2018, 54 (48), pp.6173-6176. ⟨10.1039/c8cc02035c⟩. ⟨hal-01803849⟩

François Guérard, Maryline Beyler, Y.-S Lee, Raphaël Tripier, Jean-François Gestin, et al.. Investigation of the complexation of nat Zr(IV) and 89 Zr(IV) by hydroxypyridinones for the development of chelators for PET imaging applications. Dalton Transactions, Royal Society of Chemistry, 2017, 46, pp.4749-4758. ⟨10.1039/c6dt04625h⟩. ⟨inserm-01496515⟩

Mariane Le Fur, Maryline Beyler, Eniko Molnar, Olivier Fougere, David Esteban-Gomez, et al.. The role of the capping bond effect on pyclen Y-nat(3+)/Y-90(3+) chelates: full control of the regiospecific N-functionalization makes the difference. Chemical Communications, Royal Society of Chemistry, 2017, 53 (69), pp.9534-9537. ⟨10.1039/c7cc05088g⟩. ⟨hal-01616222⟩

Mathieu Frindel, Patricia Le Saec, Maryline Beyler, Anne-Sophie Navarro, Catherine Sai-Maurel, et al.. Cyclam te1pa for 64 Cu PET imaging. Bioconjugation to antibody, radiolabeling and preclinical application in xenografted colorectal cancer. RSC Advances, Royal Society of Chemistry, 2017, 7, pp.9272-9283. ⟨10.1039/c6ra26003a⟩. ⟨inserm-01463724⟩

Anh Thy Bui, Maryline Beyler, Alexei Grichine, Alain Duperray, Jean-Christophe Mulatier, et al.. Near infrared two photon imaging using a bright cationic Yb(III) bioprobe spontaneously internalized into live cells. Chemical Communications, Royal Society of Chemistry, 2017, 53, pp.6005-6008 ⟨10.1039/C7CC02835K⟩. ⟨hal-01526221⟩

Diego Santo Domingo Porqueras, Maryline Beyler, Raphaël Tripier, Milena Salerno. Intracellular Transport Studies of Picolinate Macrocyclic Copper and Lanthanide Complexes. ChemistrySelect, Wiley, 2016, 1 (15), pp.4423 - 4429. ⟨10.1002/slct.201600990⟩. ⟨hal-01518187⟩

Anh Thy Bui, Maryline Beyler, Yuan-Yuan Liao, Alexei Grichine, Alain Duperray, et al.. Cationic Two-Photon Lanthanide Bioprobes Able to Accumulate in Live Cells. Inorganic Chemistry, American Chemical Society, 2016, 55 (14), pp.7020 - 7025. ⟨10.1021/acs.inorgchem.6b00891⟩. ⟨hal-01517789⟩

Aurora Rodríguez-Rodríguez, Zakaria Halime, Luís M. P. Lima, Maryline Beyler, David Deniaud, et al.. Cyclams with Ambidentate Methylthiazolyl Pendants for Stable, Inert, and Selective Cu(II) Coordination. Inorganic Chemistry, American Chemical Society, 2016, 55 (2), pp.619-632. ⟨10.1021/acs.inorgchem.5b01779⟩. ⟨hal-01517782⟩

Mariane Le Fur, Maryline Beyler, Nicolas Le Poul, Luís M. P. Lima, Yves Le Mest, et al.. Improving the stability and inertness of Cu( ii ) and Cu( i ) complexes with methylthiazolyl ligands by tuning the macrocyclic structure. Dalton Transactions, Royal Society of Chemistry, 2016, 45 (17), pp.7406 - 7420. ⟨10.1039/C6DT00385K⟩. ⟨hal-01518185⟩

Mariane Le Fur, Maryline Beyler, Nicolas Lepareur, Olivier Fougère, Carlos Platas-Iglesias, et al.. Pyclen Tri- n -butylphosphonate Ester as Potential Chelator for Targeted Radiotherapy: From Yttrium(III) Complexation to 90 Y Radiolabeling. Inorganic Chemistry, American Chemical Society, 2016, 55 (16), pp.8003 - 8012. ⟨10.1021/acs.inorgchem.6b01135⟩. ⟨hal-01517774⟩

Aurora Rodríguez-Rodríguez, Zoltán Garda, Erika Ruscsák, David Esteban-Gómez, Andrés de Blas, et al.. Stable Mn 2+ , Cu 2+ and Ln 3+ complexes with cyclen-based ligands functionalized with picolinate pendant arms. Dalton Transactions, Royal Society of Chemistry, 2015, 44 (11), pp.5017 - 5031. ⟨10.1039/C4DT02985B⟩. ⟨hal-01518182⟩

Nathalie Camus, Zakaria Halime, Nathalie Le Bris, Hélène Bernard, Maryline Beyler, et al.. A [two-step/one week] synthesis of C-functionalized homocyclens and cyclams. Application to the preparation of conjugable BCAs without chelating properties alteration. RSC Advances, Royal Society of Chemistry, 2015, 5 (104), pp.85898 - 85910. ⟨10.1039/c5ra17133d⟩. ⟨hal-01517785⟩

Diego Santo Domingo Porqueras, Raphaël Tripier, Maryline Beyler, Milena Salerno. Targeting amyloid peptide using metal complexes. Alzheimer's and Dementia, Elsevier, 2015, 11 (7), ⟨10.1016/j.jalz.2015.06.355⟩. ⟨hal-01538483⟩

Luís M. P. Lima, Maryline Beyler, Rita Delgado, Carlos Platas-Iglesias, Raphaël Tripier. Investigating the Complexation of the Pb 2+ /Bi 3+ Pair with Dipicolinate Cyclen Ligands. Inorganic Chemistry, American Chemical Society, 2015, 54 (14), pp.7045 - 7057. ⟨10.1021/acs.inorgchem.5b01079⟩. ⟨hal-01517764⟩

Fatima Oukhatar, Maryline Beyler, Raphaël Tripier. Straightforward and mild deprotection methods of N-mono- and N1,N7-functionalised bisaminal cyclens. Tetrahedron, Elsevier, 2015, 71 (23), pp.3857 - 3862. ⟨10.1016/j.tet.2015.04.021⟩. ⟨hal-01518184⟩

Hong Tao Liu, Aline Nonat, Maryline Beyler, Martin Regueiro-Figueroa, Katia Nchimi Nono, et al.. Supramolecular Luminescent Lanthanide Dimers for Fluoride Sequestering and Sensing. Angewandte Chemie, Wiley-VCH Verlag, 2014, 53 (28), pp.7259-7263. ⟨10.1002/anie.201404847⟩. ⟨hal-01151723⟩

Luís M. P. Lima, Maryline Beyler, Fatima Oukhatar, Patricia Le Saec, Alain Faivre-Chauvet, et al.. H2Me-do2pa: an attractive chelator with fast, stable and inert nat Bi 3+ and 213 Bi 3+ complexation for potential α-radioimmunotherapy applications. Chemical Communications, Royal Society of Chemistry, 2014, 50 (82), pp.12371 - 12374. ⟨10.1039/C4CC05529B⟩. ⟨hal-01517757⟩

Maryline Beyler, Salah Ezzaher, Michael Karnahl, Marie-Pierre Santoni, Reiner Lomoth, et al.. Pentacoordinate iron complexes as functional models of the distal iron in [FeFe] hydrogenases. Chemical Communications, Royal Society of Chemistry, 2011, 47 (42), pp.6005 - 6008. ⟨10.1039/C1CC14449A⟩. ⟨hal-01561943⟩

Maryline Beyler, Valérie Heitz, Jean-Pierre Sauvage. Coordination Chemistry-Assembled Porphyrinic Catenanes. Journal of the American Chemical Society, American Chemical Society, 2010, 132 (12), pp.4409 - 4417. ⟨10.1021/ja910747h⟩. ⟨hal-01618639⟩

Maryline Beyler, Valérie Heitz, Jean-Pierre Sauvage. Quantitative formation of a tetraporphyrin [2]catenane via copper and zinc coordination. Chemical Communications, Royal Society of Chemistry, 2008, ⟨10.1039/B811013A⟩. ⟨hal-01561945⟩

Mariane Le Fur, Gwladys Nizou, Maryline Beyler, Olivier Rousseaux, Raphaël Tripier. REINFORCED MACROCYCLIC LIGANDS, COMPLEXES THEREOF, AND USES OF SAME. France, Patent n° : brevet d'invention FRANCE No.17 55933 WO2019002505 Application: Jun 28, 2018, WO 2018-EP67482. 2019. ⟨hal-02088679⟩

Nadège Hamon, Maryline Beyler, Olivier Maury, Raphaël Tripier. Pyclen-based macrocyclic ligands, chelates thereof and uses thereof.. France, Patent n° : EP 18 305 380.0. 2018. ⟨hal-02089669⟩

Fatima Oukhatar, Maryline Beyler, Raphaël Tripier. Bifunctional do2pa derivatives, chelates with metallic cations and use thereof. France, Patent n° : EP 14 196 637.4. 2016. ⟨hal-01532109⟩

Raphaël Tripier, Carlos Platas-Iglesias, Luis Lima, Maryline Beyler. Chelates of Lead (II) and Bismuth (III) Based on Trans-Di-N-Picolinate Tetraazacycloalkanes. France, Patent n° : WO2014195416 - 2014-12-11, PCT/EP2014061723 - 2014-06-05  . 2016. ⟨hal-01532038⟩

Mariane Le Fur, Raphaël Tripier, Olivier Rousseaux, Maryline Beyler. Macrocyclic ligands with picolinate groups, their complexes like their medical uses. France, N° de brevet: FR3046172, Application n° FR 2015-63346 // WO 2017109217, Application n° WO2016-EP82644. 2015. ⟨hal-01620537⟩

Gwladys Nizou, Chiara Favaretto, Francesca Borgna, Pascal Grundler, Nathalie Saffon-Merceron, et al.. Expanding the Scope of Pyclen-Picolinate Lanthanide Chelates to Po-Tential Theranostic Applications. 2020. ⟨hal-02891584⟩

Laura Abad Galan, Nadège Hamon, Christopher Nguyen, Eniko Molnar, János Kiss, et al.. Design of Polyazamacrocyclic Gd 3+ Theranostic Agent Combining MRI and Two-Photon PDT. 2020. ⟨hal-03018923⟩

Gwladys Nizou, Enikő Molnár, Nadège Hamon, Ferenc Kalman, Olivier Fougere, et al.. Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Gadolinium Complexation. 2020. ⟨hal-03060658⟩