Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

47 résultats

Development of a L-Tryptophan-Based Ligand for Regioselective Copper Catalyzed N 2 -Arylation of 1,2,3-Triazoles

Alexandra Basilio Lopes , Patrick Wagner , Arthur Eugen Kümmerle , Frédéric Bihel , Jean-Jacques Bourguignon , et al.
ChemistrySelect, 2017, 2 (22), pp.6544-6548. ⟨10.1002/slct.201701498⟩
Article dans une revue hal-02368798v1

Development of a Peptidomimetic Antagonist of Neuropeptide FF Receptors for the Prevention of Opioid-Induced Hyperalgesia

Frédéric Bihel , Jean-Paul Humbert , Severine Schneider , Isabelle Bertin , Patrick Wagner , et al.
ACS Chemical Neuroscience, 2015, 6 (3), pp.438-445. ⟨10.1021/cn500219h⟩
Article dans une revue hal-03198603v1
Image document

TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis

Imane Lejri , Amandine Grimm , François Hallé , Mustapha Abarghaz , Christian Klein , et al.
Journal of Alzheimer's Disease, In press, pp.1-14. ⟨10.3233/JAD-190127⟩
Article dans une revue hal-02368657v1

Evidence for the involvement of TNF-α, IL-1β and IL-10 in the antinociceptive and anti-inflammatory effects of indole-3-guanylhydrazone hydrochloride, an aromatic aminoguanidine, in rodents

Silvia M.S. Sandes , Luana Heimfarth , Renan Brito , Priscila Santos , Daniele Gouveia , et al.
Chemico-Biological Interactions, 2018, 286, pp.1-10. ⟨10.1016/j.cbi.2018.02.026⟩
Article dans une revue hal-02323744v1
Image document

Indole-3-guanylhydrazone hydrochloride mitigates long-term cognitive impairment in a neonatal sepsis model with involvement of MAPK and NFκB pathways

Luana Heimfarth , Alexandra Maria Santos Carvalho , Jullyana de Souza Siqueira Quintans , Erik Willyame Menezes Pereira , Natália Teles Lima , et al.
Neurochemistry International, 2020, 134, pp.104647. ⟨10.1016/j.neuint.2019.104647⟩
Article dans une revue hal-02908631v1
Image document

Coumarin Derivatives Exert Anti-Lung Cancer Activity by Inhibition of Epithelial–Mesenchymal Transition and Migration in A549 Cells

Rodrigo Santos Aquino de Araújo , Julianderson de Oliveira dos Santos Carmo , Simone Lara de Omena Silva , Camila Radelley Azevedo Costa da Silva , Tayhana Priscila Medeiros Souza , et al.
Pharmaceuticals, 2022, 15 (1), pp.104. ⟨10.3390/ph15010104⟩
Article dans une revue hal-03796428v1
Image document

Fukuyama Cross-Coupling Approach to Isoprekinamycin: Discovery of the Highly Active and Bench-Stable Palladium Precatalyst POxAP

Shuang-Qi Tang , Jacques Bricard , Martine Schmitt , Frédéric Bihel
Organic Letters, 2019, 21 (3), pp.844-848. ⟨10.1021/acs.orglett.9b00031⟩
Article dans une revue hal-02323246v1

Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors

Ronan Gealageas , Severine Schneider , Jean-Paul Humbert , Isabelle Bertin , Martine Schmitt , et al.
Bioorganic and Medicinal Chemistry Letters, 2012, 22 (24), pp.7471-7474. ⟨10.1016/j.bmcl.2012.10.049⟩
Article dans une revue istex hal-02993696v1
Image document

Identification of an N -acylated- D Arg-Leu-NH 2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Raphaëlle Quillet , Séverine Schneider , Valérie Utard , Armand Drieu La Rochelle , Khadija Elhabazi , et al.
Journal of Medicinal Chemistry, 2021, 64 (11), pp.7555-7564. ⟨10.1021/acs.jmedchem.1c00256⟩
Article dans une revue hal-03363456v1

Dioxygenation of styrenes with molecular oxygen in water

Shuang-Qi Tang , An-Ping Wang , Martine Schmitt , Frédéric Bihel
Tetrahedron Letters, 2018, 59 (15), pp.1465-1468. ⟨10.1016/j.tetlet.2018.03.009⟩
Article dans une revue hal-02326129v1

Unusual O-Bridged Symmetric Quinoline-Based Ligand for the Formation of Luminescent Mono-Aqua Lanthanide Complexes

Hassan Hammoud , Ana De bettencourt-Dias , Martine Schmitt , Jorge H. S. K. Monteiro , Jeffrey S. Rossini , et al.
ChemistrySelect, 2016, 1 (21), pp.6618-6622. ⟨10.1002/slct.201601223⟩
Article dans une revue hal-03536462v1
Image document

Xanthurenic acid binds to neuronal G-protein-coupled receptors that secondarily activate cationic channels in the cell line NCB-20.

Omar Taleb , Mohammed Maammar , Daniel Brumaru , Jean-Jacques Bourguignon , Martine Schmitt , et al.
PLoS ONE, 2012, 7 (11), pp.e48553. ⟨10.1371/journal.pone.0048553⟩
Article dans une revue hal-02612148v1

Evolution of coumaroyl conjugate 3‐hydroxylases in land plants: lignin biosynthesis and defense

Annette Alber , Hugues Renault , Alexandra Basilio-Lopes , Jean-Etienne Bassard , Zhenhua Liu , et al.
Plant Journal, 2019, 99 (5), pp.924-936. ⟨10.1111/tpj.14373⟩
Article dans une revue hal-02437982v1

RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.

Frédéric Simonin , Martine Schmitt , Jean-Paul Laulin , Emilie Laboureyras , Jack H Jhamandas , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (2), pp.466-71. ⟨10.1073/pnas.0502090103⟩
Article dans une revue hal-00188146v1
Image document

Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

Maud Bollenbach , Claire Lugnier , M Elanie Kremer , Eric Salvat , Salim Megat , et al.
European Journal of Medicinal Chemistry, 2019, 177, pp.269-290. ⟨10.1016/j.ejmech.2019.05.026⟩
Article dans une revue hal-02322399v1
Image document

POxAP Precatalysts and the Negishi Cross-Coupling Reaction

Shuang-Qi Tang , Martine Schmitt , Frédéric Bihel
Synthesis: Journal of Synthetic Organic Chemistry, 2019, 52 (01), pp.51-59. ⟨10.1055/s-0039-1690728⟩
Article dans une revue hal-02997250v1
Image document

Preliminary in vitro evaluation of the anti-proliferative activity of guanylhydrazone derivatives

Paulo H. B. França , Edeildo F. da Silva-Júnior , Pedro G. V. Aquino , Antônio E. G. Santana , Jamylle N. S. Ferro , et al.
Acta Pharmaceutica, 2016, 66 (1), pp.129-137. ⟨10.1515/acph-2016-0015⟩
Article dans une revue hal-03536478v1

Neuropeptide FF receptors as novel targets for limbic seizure attenuation

Jeanelle Portelli , Alfred Meurs , Frederic Bihel , Hassan Hammoud , Martine Schmitt , et al.
Neuropharmacology, 2015, 95, pp.415-423. ⟨10.1016/j.neuropharm.2015.04.030⟩
Article dans une revue hal-03005155v1

Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103

Laurent Rouméas , Jean-Paul Humbert , Séverine Schneider , Christelle Doebelin , Isabelle Bertin , et al.
Peptides, 2015, 71, pp.156-161. ⟨10.1016/j.peptides.2015.07.016⟩
Article dans une revue hal-02997151v1
Image document

Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies

Amandine Grimm , Imane Lejri , François Hallé , Martine Schmitt , Jürgen Götz , et al.
Journal of Neuroendocrinology, 2019, ⟨10.1111/jne.12796⟩
Article dans une revue hal-02368671v1

Development of Dipeptidic hGPR54 Agonists

Christelle Doebelin , Isabelle I. Bertin , Séverine Schneider , Martine Schmitt , Jean-Jacques Bourguignon , et al.
ChemMedChem, 2016, 11 (19), pp.2147-2154. ⟨10.1002/cmdc.201600331⟩
Article dans une revue istex hal-02368845v1
Image document

Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

Martine Schmitt , Thiago M. De Aquino , Paulo H.B. França , Érica E. E. S. . Rodrigues , Igor, J. S. Nascimento , et al.
Medicinal Chemistry, In press, ⟨10.2174/1573406417666210216154428⟩
Article dans une revue hal-03407968v1

On water N -arylation of oxetanylamines for the preparation of N -aryl-oxetanylamines; potentially useful aryl-amide isosteres

Maud Bollenbach , William Lecroq , Patrick Wagner , Thomas Fessard , Martine Schmitt , et al.
Chemical Communications, 2019, 55 (11), pp.1623-1626. ⟨10.1039/c8cc09110b⟩
Article dans une revue hal-02322869v1
Image document

Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine

Shuang-Qi Tang , Maeva Leloire , Severine Schneider , Julie Mohr , Jacques Bricard , et al.
Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.0c01764⟩
Article dans une revue hal-03021041v1

Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization

François Hallé , Olivier van Der Poorten , Christelle Doebelin , Marie Niederst , Séverine Schneider , et al.
Tetrahedron Letters, 2016, 57 (14), pp.1547-1550. ⟨10.1016/j.tetlet.2016.02.094⟩
Article dans une revue hal-02290245v1
Image document

Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review

Sonaly Lima Albino , Jamire Muriel da Silva , Michelangela Suelleny de Caldas Nobre , Yvnni Maria Sales de Medeiros E Silva , Mirelly Barbosa Santos , et al.
Current Pharmaceutical Design, In press, ⟨10.2174/1381612826666200701160904⟩
Article dans une revue hal-02908646v1

Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein

François Hallé , Imane Lejri , Mustapha Abarghaz , Amandine Grimm , Christian Klein , et al.
ChemistrySelect, 2017, 2 (22), pp.6452-6457. ⟨10.1002/slct.201701565⟩
Article dans une revue hal-02368811v1
Image document

A phenol-enriched cuticle is ancestral to lignin evolution in land plants

Hugues Renault , Annette Alber , Nelly Horst , Alexandra Basilio Lopes , Eric Fich , et al.
Nature Communications, 2017, 8 (1), pp.14713. ⟨10.1038/ncomms14713⟩
Article dans une revue hal-02437962v1

Protein–Protein and Protein–Membrane Associations in the Lignin Pathway

Jean-Etienne Bassard , Ludovic Richert , Jan Geerinck , Hugues Renault , Frédéric Duval , et al.
The Plant cell, 2012, 24 (11), pp.4465-4482. ⟨10.1105/tpc.112.102566⟩
Article dans une revue hal-02438016v1
Image document

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice

Cyril Rivat , Chamroeun Sar , Ilana Mechaly , J.P. Leyris , Lucie Diouloufet , et al.
Nature Communications, 2018, 9 (1), pp.1042. ⟨10.1038/s41467-018-03496-2⟩
Article dans une revue hal-02158159v1