Martin Villalba

Tania Calvo, Chantal Reina‑ortiz, David Giraldos, María Gascón, Daniel Woods, et al.. Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance. Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76051-z⟩. ⟨hal-03010044⟩

Martin Villalba, Catherine Alexia, Anais Bellin-Robert, Alexis Fayd'herbe de Maudave, Delphine Gitenay. Naturally improving the natural cytotoxicity of natural killer (NK) cells. Frontiers in Immunology, Frontiers, 2020, 10, pp.3026. ⟨10.3389/fimmu.2019.03026⟩. ⟨inserm-02711666⟩

Vo Dang-Nghiem, Michael Constantinides, Nerea Allende-Vega, Catherine Alexia, Guillaume Cartron, et al.. Dissecting the NK cell population in hematological cancers confirms the presence of tumor cells and their impact on NK population function. Vaccines, MDPI, In press, 8. ⟨hal-03031877⟩

Alberto Anel, Julián Pardo, Martin Villalba. Editorial: The Natural Killer Cell Interactome in the Tumor Microenvironment: Basic Concepts and Clinical Application. Frontiers in Immunology, Frontiers, 2020, 11, pp.872. ⟨10.3389/fimmu.2020.00872⟩. ⟨hal-02924407⟩

Joaquín Marco-Brualla, Sameer Al-Wasaby, Ruth Soler, Eduardo Romanos, Blanca Conde, et al.. Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells.. Cancers, MDPI, 2019, 11 (7), pp.E1027. ⟨10.3390/cancers11071027⟩. ⟨inserm-02334214⟩

Martin Villalba, Nerea Allende-Vega. Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells. Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.5637. ⟨10.1038/s41598-019-42220-y⟩. ⟨inserm-02334210⟩

Catherine Alexia, Maïlys Cren, Pascale Louis-Plence, Dang-Nghiem Vo, Yasamine El Ahmadi, et al.. Polyoxidonium® Activates Cytotoxic Lymphocyte Responses Through Dendritic Cell Maturation: Clinical Effects in Breast Cancer. Frontiers in Immunology, Frontiers, 2019, 10, pp.2693. ⟨10.3389/fimmu.2019.02693⟩. ⟨hal-02414398⟩

Abrar Ul Haq Khan, Nerea Allende-Vega, Delphine Gitenay, Johan Garaude, Dang-Nghiem Vo, et al.. Mitochondrial Complex I activity signals antioxidant response through ERK5. Scientific Reports, Nature Publishing Group, 2018, 8 (1), ⟨10.1038/s41598-018-23884-4⟩. ⟨hal-01835615⟩

Sana Belkahla, Abrar Ul Haq Khan, Delphine Gitenay, Catherine Alexia, Claire Gondeau, et al.. Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status. Oncotarget, Impact journals, 2018, 9 (1), pp.1114--1129. ⟨10.18632/oncotarget.23305⟩. ⟨hal-02345948⟩

Diego Sanchez, Nerea Allende-Vega, Stefania Orecchioni, Giovanna Talarico, Amélie Cornillon, et al.. Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors. Theranostics, Ivyspring International Publisher, 2018, 8 (14), pp.3856-3869. ⟨10.7150/thno.25149⟩. ⟨inserm-02351977⟩

Abrar Ul Haq Khan, Nerea Allende-Vega, Delphine Gitenay, Sabine Gerbal-Chaloin, Claire Gondeau, et al.. The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway. Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-10339-5⟩. ⟨hal-01835605⟩

Abrar Ul Haq Khan, Moeez Rathore, Nerea Allende-Vega, Dang-Nghiem Vo, Sana Belkhala, et al.. Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production. EBioMedicine, Elsevier, 2016, 3, pp.43 - 53. ⟨10.1016/j.ebiom.2015.11.045⟩. ⟨hal-01877446⟩

Diego Sánchez-Martínez, Pilar Lanuza, Natalia Gómez, Aura Muntasell, Elisa Cisneros, et al.. Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells. Frontiers in Immunology, Frontiers, 2016, 7, ⟨10.3389/fimmu.2016.00454⟩. ⟨hal-01835596⟩

Ewelina Krzywinska, Amélie Cornillon, Nerea Allende-Vega, Dang-Nghiem Vo, Céline René, et al.. CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity. PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0150434. ⟨10.1371/journal.pone.0150434⟩. ⟨inserm-01867110⟩

Martin Sanchez-Martinez, Gemma Azaceta, Aura Muntasell, Nacho Aguiló, David Nuñez, et al.. Human NK cells activated by EBV + lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells. OncoImmunology, Taylor & Francis, 2015, 4 (3), ⟨10.4161/2162402X.2014.991613⟩. ⟨hal-01835574⟩

Ewelina Krzywinska, Nerea Allende-Vega, Amélie Cornillon, Dang-Nghiem Vo, Laure Cayrefourcq, et al.. Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers. EBioMedicine, Elsevier, 2015, 2 (10), pp.1364 - 1376. ⟨10.1016/j.ebiom.2015.08.021⟩. ⟨inserm-01867114⟩

Nerea Allende-Vega, Ewelina Krzywinska, Stefania Orecchioni, Nuria Lopez-Royuela, Francesca Reggiani, et al.. The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism. Oncotarget, Impact journals, 2015, 6 (22), pp.19228-45. ⟨10.18632/oncotarget.4653⟩. ⟨inserm-01868552⟩

Elena Catalán, Seyma Charni, Paula Jaime, Juan Ignacio Aguilo, José Antonio Enríquez, et al.. MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells. OncoImmunology, Taylor & Francis, 2015, 4 (1), ⟨10.4161/2162402X.2014.985924⟩. ⟨hal-01835539⟩

Céline René, Claire Lozano, Martin Villalba, Jean-François Eliaou. 5′ and 3′ untranslated regions contribute to the differential expression of specific HLA-A alleles. European Journal of Immunology, Wiley-VCH Verlag, 2015, 45 (12), pp.3454 - 3463. ⟨10.1002/eji.201545927⟩. ⟨hal-01835556⟩

Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez Rathore, Robert Hipskind, et al.. Chemical Metabolic Inhibitors For The Treatment Of Blood-Borne Cancers.. Current Medicinal Chemistry Anticancer Agents, Bentham Science Publishers, 2014, 14 (2), pp.223-32. ⟨10.2174/18715206113136660374⟩. ⟨inserm-01867009v2⟩

Nuria Lopez-Royuela, Moeez Rathore, Nerea Allende-Vega, Jean-Sébastien Annicotte, Lluis Fajas, et al.. Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells. International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 53, pp.253 - 261. ⟨10.1016/j.biocel.2014.05.026⟩. ⟨inserm-01867017⟩

Sophie Auger, Mattea Orsini, Patrice Céballos, Nathalie Fegueux, Tarik Kanouni, et al.. Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival. European Journal of Haematology, Wiley, 2014, 92 (5), pp.421 - 428. ⟨10.1111/ejh.12260⟩. ⟨inserm-01867012⟩

Diego Sánchez-Martínez, Ewelina Krzywinska, Moeez Rathore, Anne Saumet, Amélie Cornillon, et al.. All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity. International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 49, pp.42 - 52. ⟨10.1016/j.biocel.2014.01.003⟩. ⟨inserm-01867016⟩

Gauthier Bouche, Nicolas André, Shripad Banavali, Frank Berthold, Alfredo Berruti, et al.. Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24–25 June 2014, Milan. Ecancer medical science/Ecancermedicalscience - http://www-ncbi-nlm-nih-gov.gate2.inist.fr/pmc/journals/899/ - http://www.ecancer.org/ecms, Bristol, UK : Cancer Intelligence (10.3332/ecancer)., 2014, 8, pp.463. ⟨10.3332/ecancer.2014.463⟩. ⟨inserm-01867014⟩

Natalia Comet, Juan Ignacio Aguilo, Moeez Rathoré, Elena Catalán, Johan Garaude, et al.. IFNα signaling through PKC-θ is essential for antitumor NK cell function. OncoImmunology, Taylor & Francis, 2014, 3 (8), pp.e948705. ⟨10.4161/21624011.2014.948705⟩. ⟨hal-03108492⟩

Martin Villalba, Moeez Rathore, Nuria Lopez-Royuela, Ewelina Krzywinska, Johan Garaude, et al.. From tumor cell metabolism to tumor immune escape.. International Journal of Biochemistry and Cell Biology, Elsevier, 2013, 45 (1), pp.106-13. ⟨10.1016/j.biocel.2012.04.024⟩. ⟨inserm-00726717⟩

Sandra Kaminski, Oumeya Adjali, Chantal Jacquet, Johan Garaude, Anne Keriel, et al.. The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.. OncoImmunology, Taylor & Francis, 2012, 1 (5), pp.600-608. ⟨10.4161/onci.20225⟩. ⟨inserm-00726759⟩

Alberto Anel, Juan Aguiló, Elena Catalán, Johan Garaude, Moeez Rathore, et al.. Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity.. Frontiers in Immunology, Frontiers, 2012, 3, pp.187. ⟨10.3389/fimmu.2012.00187⟩. ⟨inserm-00726668⟩

Moeez Rathore, Anne Saumet, Jean-François Rossi, Carine de Bettignies, Denis Tempé, et al.. The NF-κB member p65 controls glutamine metabolism through miR-23a.. International Journal of Biochemistry and Cell Biology, Elsevier, 2012, 44 (9), pp.1448-56. ⟨10.1016/j.biocel.2012.05.011⟩. ⟨inserm-00726691⟩

Seyma Charni, Juan Ignacio Aguilo, Johan Garaude, Geoffroy de Bettignies, Chantal Jacquet, et al.. ERK5 Knockdown generates mouse leukemia cells with low MHC class i levels that activate NK cells and block tumorigenesis.. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (6), pp.3398-405. ⟨10.4049/jimmunol.0803006⟩. ⟨hal-00368654⟩