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Number of documents

47

Martin Villalba


Journal articles47 documents

  • Alexis Fayd'Herbe de Maudave, Wilhem Leconet, Karine Toupet, Michael Constantinides, Guillaume Bossis, et al.. Intra-articular delivery of full-length antibodies through the use of an in situ forming depot. Journal of Controlled Release, Elsevier, 2022, 341, pp.578-590. ⟨10.1016/j.jconrel.2021.12.010⟩. ⟨hal-03563900⟩
  • Chantal Reina-Ortiz, David Giraldos, Gemma Azaceta, Luis Palomera, Isabel Marzo, et al.. Harnessing the Potential of NK Cell-Based Immunotherapies against Multiple Myeloma. Cells, MDPI, 2022, 11 (3), pp.392. ⟨10.3390/cells11030392⟩. ⟨hal-03585338⟩
  • Nerea Allende-Vega, Joaquin Marco Brualla, Paolo Falvo, Catherine Alexia, Michael Constantinides, et al.. Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1). Scientific Reports, Nature Publishing Group, 2022, 12 (1), pp.1341. ⟨10.1038/s41598-022-05470-x⟩. ⟨hal-03564112⟩
  • Sana Belkahla, Joaquin Marco Brualla, Alexis Fayd’herbe de Maudave, Paolo Falvo, Nerea Allende-Vega, et al.. The metabolism of cells regulates their sensitivity to NK cells depending on p53 status. Scientific Reports, Nature Publishing Group, 2022, 12 (1), pp.3234. ⟨10.1038/s41598-022-07281-6⟩. ⟨hal-03595038⟩
  • Chantal Reina-Ortiz, Michael Constantinides, Alexis Fayd-Herbe-De-Maudave, Jessy Présumey, Javier Hernandez, et al.. Expanded NK cells from umbilical cord blood and adult peripheral blood combined with daratumumab are effective against tumor cells from multiple myeloma patients. OncoImmunology, Taylor & Francis, 2021, 10 (1), pp.1853314. ⟨10.1080/2162402X.2020.1853314⟩. ⟨hal-03163825⟩
  • Karim Mrouj, Nuria Andrés-Sánchez, Geronimo Dubra, Priyanka Singh, Michal Sobecki, et al.. Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (10), pp.e2026507118. ⟨10.1073/pnas.2026507118⟩. ⟨hal-03364397⟩
  • Dang-Nghiem Vo, Michael Constantinides, Nerea Allende-Vega, Catherine Alexia, Guillaume Cartron, et al.. Dissecting the NK cell population in hematological cancers confirms the presence of tumor cells and their impact on NK population function. Vaccines, MDPI, 2020, 8 (4), pp.727. ⟨10.3390/vaccines8040727⟩. ⟨hal-03031877⟩
  • Alberto Anel, Julián Pardo, Martin Villalba. Editorial: The Natural Killer Cell Interactome in the Tumor Microenvironment: Basic Concepts and Clinical Application. Frontiers in Immunology, Frontiers, 2020, 11, pp.872. ⟨10.3389/fimmu.2020.00872⟩. ⟨hal-02924407⟩
  • Tania Calvo, Chantal Reina‑ortiz, David Giraldos, María Gascón, Daniel Woods, et al.. Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19398. ⟨10.1038/s41598-020-76051-z⟩. ⟨hal-03010044⟩
  • Martin Villalba, Catherine Alexia, Anais Bellin-Robert, Alexis Fayd'Herbe de Maudave, Delphine Gitenay. Naturally improving the natural cytotoxicity of natural killer (NK) cells. Frontiers in Immunology, Frontiers, 2020, 10, pp.3026. ⟨10.3389/fimmu.2019.03026⟩. ⟨inserm-02711666⟩
  • Catherine Alexia, Maïlys Cren, Pascale Louis-Plence, Dang-Nghiem Vo, Yasamine El Ahmadi, et al.. Polyoxidonium® Activates Cytotoxic Lymphocyte Responses Through Dendritic Cell Maturation: Clinical Effects in Breast Cancer. Frontiers in Immunology, Frontiers, 2019, 10, pp.2693. ⟨10.3389/fimmu.2019.02693⟩. ⟨hal-02414398⟩
  • Martin Villalba, Nerea Allende-Vega. Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells. Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.5637. ⟨10.1038/s41598-019-42220-y⟩. ⟨inserm-02334210⟩
  • Joaquín Marco-Brualla, Sameer Al-Wasaby, Ruth Soler, Eduardo Romanos, Blanca Conde, et al.. Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells.. Cancers, MDPI, 2019, 11 (7), pp.E1027. ⟨10.3390/cancers11071027⟩. ⟨inserm-02334214⟩
  • Sana Belkahla, Abrar Ul Haq Khan, Delphine Gitenay, Catherine Alexia, Claire Gondeau, et al.. Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status. Oncotarget, Impact journals, 2018, 9 (1), pp.1114--1129. ⟨10.18632/oncotarget.23305⟩. ⟨hal-02345948⟩
  • Diego Sanchez, Nerea Allende-Vega, Stefania Orecchioni, Giovanna Talarico, Amélie Cornillon, et al.. Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors. Theranostics, Ivyspring International Publisher, 2018, 8 (14), pp.3856-3869. ⟨10.7150/thno.25149⟩. ⟨inserm-02351977⟩
  • Abrar Ul Haq Khan, Nerea Allende-Vega, Delphine Gitenay, Johan Garaude, Dang-Nghiem Vo, et al.. Mitochondrial Complex I activity signals antioxidant response through ERK5. Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.7420. ⟨10.1038/s41598-018-23884-4⟩. ⟨hal-01835615⟩
  • Dang-Nghiem Vo, Catherine Alexia, Nerea Allende-Vega, Franck Morschhauser, Roch Houot, et al.. NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment. OncoImmunology, Taylor & Francis, 2018, 7 (4), pp.e1409322. ⟨10.1080/2162402X.2017.1409322⟩. ⟨hal-01780378⟩
  • Abrar Ul Haq Khan, Nerea Allende-Vega, Delphine Gitenay, Sabine Gerbal-Chaloin, Claire Gondeau, et al.. The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway. Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-10339-5⟩. ⟨hal-01835605⟩
  • Ewelina Krzywinska, Amélie Cornillon, Nerea Allende-Vega, Dang-Nghiem Vo, Céline René, et al.. CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity. PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0150434. ⟨10.1371/journal.pone.0150434⟩. ⟨inserm-01867110⟩
  • Diego Sánchez-Martínez, Pilar Lanuza, Natalia Gómez, Aura Muntasell, Elisa Cisneros, et al.. Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells. Frontiers in Immunology, Frontiers, 2016, 7, pp.454. ⟨10.3389/fimmu.2016.00454⟩. ⟨hal-01835596⟩
  • Abrar Ul Haq Khan, Moeez G. Rathore, Nerea Allende-Vega, Dang-Nghiem Vo, Sana Belkhala, et al.. Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production. EBioMedicine, Elsevier, 2016, 3, pp.43 - 53. ⟨10.1016/j.ebiom.2015.11.045⟩. ⟨hal-01877446⟩
  • Martin Sanchez-Martinez, Gemma Azaceta, Aura Muntasell, Nacho Aguiló, David Nuñez, et al.. Human NK cells activated by EBV + lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells. OncoImmunology, Taylor & Francis, 2015, 4 (3), pp.e991613. ⟨10.4161/2162402X.2014.991613⟩. ⟨hal-01835574⟩
  • Nerea Allende-Vega, Ewelina Krzywinska, Stefania Orecchioni, Nuria Lopez-Royuela, Francesca Reggiani, et al.. The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism. Oncotarget, Impact journals, 2015, 6 (22), pp.19228-45. ⟨10.18632/oncotarget.4653⟩. ⟨inserm-01868552v2⟩
  • Ewelina Krzywinska, Nerea Allende-Vega, Amélie Cornillon, Dang-Nghiem Vo, Laure Cayrefourcq, et al.. Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers. EBioMedicine, Elsevier, 2015, 2 (10), pp.1364 - 1376. ⟨10.1016/j.ebiom.2015.08.021⟩. ⟨inserm-01867114⟩
  • Céline René, Claire Lozano, Martin Villalba, Jean-François Eliaou. 5′ and 3′ untranslated regions contribute to the differential expression of specific HLA-A alleles. European Journal of Immunology, Wiley-VCH Verlag, 2015, 45 (12), pp.3454 - 3463. ⟨10.1002/eji.201545927⟩. ⟨hal-01835556⟩
  • Elena Catalán, Seyma Charni, Paula Jaime, Juan Ignacio Aguilo, José Antonio Enríquez, et al.. MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells. OncoImmunology, Taylor & Francis, 2015, 4 (1), ⟨10.4161/2162402X.2014.985924⟩. ⟨hal-01835539⟩
  • Gauthier Bouche, Nicolas André, Shripad Banavali, Frank Berthold, Alfredo Berruti, et al.. Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24–25 June 2014, Milan. Ecancer medical science/Ecancermedicalscience - http://www-ncbi-nlm-nih-gov.gate2.inist.fr/pmc/journals/899/ - http://www.ecancer.org/ecms, Bristol, UK : Cancer Intelligence (10.3332/ecancer)., 2014, 8, pp.463. ⟨10.3332/ecancer.2014.463⟩. ⟨inserm-01867014⟩
  • Nuria Lopez-Royuela, Moeez G. Rathore, Nerea Allende-Vega, Jean-Sébastien Annicotte, Lluis Fajas, et al.. Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells. International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 53, pp.253 - 261. ⟨10.1016/j.biocel.2014.05.026⟩. ⟨inserm-01867017⟩
  • Sophie Auger, Mattea Orsini, Patrice Céballos, Nathalie Fegueux, Tarik Kanouni, et al.. Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival. European Journal of Haematology, Wiley, 2014, 92 (5), pp.421 - 428. ⟨10.1111/ejh.12260⟩. ⟨inserm-01867012⟩
  • Natalia R. Comet, Juan Ignacio Aguilo, Moeez G. Rathoré, Elena Catalán, Johan Garaude, et al.. IFNα signaling through PKC-θ is essential for antitumor NK cell function. OncoImmunology, Taylor & Francis, 2014, 3 (8), pp.e948705. ⟨10.4161/21624011.2014.948705⟩. ⟨hal-03108492⟩
  • Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez G. Rathore, Robert A. Hipskind, et al.. Chemical Metabolic Inhibitors For The Treatment Of Blood-Borne Cancers.. Current Medicinal Chemistry Anticancer Agents, Bentham Science Publishers, 2014, 14 (2), pp.223-32. ⟨10.2174/18715206113136660374⟩. ⟨inserm-01867009v2⟩
  • Diego Sánchez-Martínez, Ewelina Krzywinska, Moeez G. Rathore, Anne Saumet, Amélie Cornillon, et al.. All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity. International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 49, pp.42 - 52. ⟨10.1016/j.biocel.2014.01.003⟩. ⟨inserm-01867016⟩
  • Diego Sánchez-Martínez, Ewelina Krzywinska, Moeez G. Rathore, Anne Saumet, Amélie Cornillon, et al.. MicroRNAs: new candidates for the regulation of the human cumulus–oocyte complex. Human Reproduction, Oxford University Press (OUP), 2013, 28 (11), pp.3038-3049. ⟨10.1093/humrep/det321⟩. ⟨hal-02106446⟩
  • Martin Villalba, Moeez G. Rathore, Nuria Lopez-Royuela, Ewelina Krzywinska, Johan Garaude, et al.. From tumor cell metabolism to tumor immune escape.. International Journal of Biochemistry and Cell Biology, Elsevier, 2013, 45 (1), pp.106-13. ⟨10.1016/j.biocel.2012.04.024⟩. ⟨inserm-00726717⟩
  • Alberto Anel, Juan I. Aguiló, Elena Catalán, Johan Garaude, Moeez G. Rathore, et al.. Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity.. Frontiers in Immunology, Frontiers, 2012, 3, pp.187. ⟨10.3389/fimmu.2012.00187⟩. ⟨inserm-00726668⟩
  • Moeez G. Rathore, Anne Saumet, Jean-François Rossi, Carine de Bettignies, Denis Tempé, et al.. The NF-κB member p65 controls glutamine metabolism through miR-23a.. International Journal of Biochemistry and Cell Biology, Elsevier, 2012, 44 (9), pp.1448-56. ⟨10.1016/j.biocel.2012.05.011⟩. ⟨inserm-00726691⟩
  • Sandra Kaminski, Oumeya Adjali, Chantal Jacquet, Johan Garaude, Anne Keriel, et al.. The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.. OncoImmunology, Taylor & Francis, 2012, 1 (5), pp.600-608. ⟨10.4161/onci.20225⟩. ⟨inserm-00726759⟩
  • J. I. Aguilo, J. Garaude, Juan Carlos Pardo, Martin Villalba, A. Anel. Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (4), pp.1972--81. ⟨10.4049/jimmunol.0801820⟩. ⟨hal-02194087⟩
  • Seyma Charni, Juan Ignacio Aguilo, Johan Garaude, Geoffroy de Bettignies, Chantal Jacquet, et al.. ERK5 Knockdown generates mouse leukemia cells with low MHC class i levels that activate NK cells and block tumorigenesis.. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (6), pp.3398-405. ⟨10.4049/jimmunol.0803006⟩. ⟨hal-00368654⟩
  • Cyrielle Clapé, Vanessa Fritz, Corinne Henriquet, Florence Apparailly, Pedro Luis Fernandez, et al.. miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice.. PLoS ONE, Public Library of Science, 2009, 4 (10), pp.e7542. ⟨10.1371/journal.pone.0007542⟩. ⟨inserm-00431462⟩
  • S. Charni, M. G. Rathore, Martin Villalba. The immune escape durin tumorigenesis: its reversibility and its clinical application. Bulletin du Cancer, John Libbey Eurotext, 2009, 96, pp.S31--S31. ⟨hal-02194093⟩
  • J. Garaude, S. Cherni, S. Kaminski, E. Delepine, C. Chable-Bessia, et al.. ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2006, 177 (11), pp.7607-7617. ⟨10.4049/jimmunol.177.11.7607⟩. ⟨hal-02262459⟩
  • J. Garaude, S. Kaminski, S. Cherni, R. A. Hipskind, Martin Villalba. The role of ERK5 in T-cell signalling. Scandinavian Journal of Immunology, Wiley, 2005, 62 (6), pp.515--20. ⟨10.1111/j.1365-3083.2005.01696.x⟩. ⟨hal-02262228⟩
  • A. Altman, S. Kaminski, V. Busuttil, N. Droin, J. R. Hu, et al.. Positive feedback regulation of PLC gamma 1/Ca2+ signaling by PKC theta in restimulated T cells via a Tec kinase-dependent pathway. European Journal of Immunology, Wiley-VCH Verlag, 2004, 34 (7), pp.2001--2011. ⟨10.1002/eji.200324625⟩. ⟨hal-02262400⟩
  • S. Kaminski, M. A. del Pozo, R. A. Hipskind, A. Altman, Martin Villalba. Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells. Scandinavian Journal of Immunology, Wiley, 2004, 59 (6), pp.527--35. ⟨10.1111/j.1365-3083.2004.01429.x⟩. ⟨hal-02262378⟩
  • Martin Villalba. What came first: PKC theta or the immune synapse?. Archivum Immunologiae et Therapiae Experimentalis, Springer Verlag, 2004, 52 (1), pp.6--12. ⟨hal-02262422⟩
  • M. A. Schwartz, J. R. Hu, W. B. Kiosses, A. Altman, Martin Villalba, et al.. Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2003, 170 (1), pp.41--47. ⟨10.4049/jimmunol.170.1.41⟩. ⟨hal-02239684⟩