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Marlene Wiart

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Présentation

CarMeN U1060 Inserm, Université Claude Bernard Lyon 1, Lyon Phone 33 4 78 78 56 10 E-mail <marlene.wiart@univ-lyon1.fr> ``` <span style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial;">Personal page: </span><a href="http://carmen-intranet.univ-lyon1.fr/membres/wiart/"><span style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Courier New';">http://carmen-intranet.univ-lyon1.fr/membres/wiart/</span></a> ``` ``` <span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;">ORCID ID: </span><a href="http://orcid.org/0000-0003-0326-7002"><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;">0000-0003-0326-7002</span></a><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;"> / </span><a href="https://www.researchgate.net/profile/Marlene_Wiart"><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;">Research Gate </span></a><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;"> / </span><a href="https://www.linkedin.com/in/marl%C3%A8ne-wiart-b0b48a11/"><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;">LinkedIn</span></a><span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Arial; mso-ansi-language: EN-US;"> </span> ``` ``` <span lang="EN-US" style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Courier New'; mso-ansi-language: EN-US;">Research statistics: <strong style="mso-bidi-font-weight: normal;">Publications</strong> 55; <strong style="mso-bidi-font-weight: normal;">h-number</strong>: 25 (Google scholar, 02 March 2021)</span> ```

Publications

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Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies

Marlène Wiart , Clément Tavakoli , Violaine Hubert , Inès Hristovska , Chloé Dumot
Journal of Neuroscience Methods, 2023, 383, pp.109729. ⟨10.1016/j.jneumeth.2022.109729⟩
Article dans une revue hal-03865234v1
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High-resolution synchrotron K-edge subtraction CT allows tracking and quantifying therapeutic cells and their scaffold in a rat model of focal cerebral injury and can serve as a reference for spectral photon counting CT

Clément Tavakoli , Elisa Cuccione , Chloé Dumot , Joëlle Balegamire , Salim Aymeric Si-Mohamed
Nanotheranostics, 2023, 7 (2), pp.176-186. ⟨10.7150/ntno.79575⟩
Article dans une revue hal-03996505v1
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In vivo targeting and multimodal imaging of cerebral amyloid-β aggregates using hybrid GdF 3 nanoparticles

Frédéric Lerouge , Elodie Ong , Hugo Rositi , Francis Mpambani , Lise-Prune Berner
Nanomedicine, 2023, 17 (29), pp.2173-2187. ⟨10.2217/nnm-2022-0252⟩
Article dans une revue hal-04038718v1
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Virtual histology of Alzheimer’s Disease: Biometal entrapment within amyloid-β plaques allows for detection via X-ray phase-contrast imaging

Matthieu Chourrout , Christophe Sandt , Timm Weitkamp , Tanja Dučić , David Meyronet
Acta Biomaterialia, 2023, 170, pp.260-272. ⟨10.1016/j.actbio.2023.07.046⟩
Article dans une revue hal-04046962v2
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Reassessment of mitochondrial cyclophilin D as a target for improving cardiac arrest outcomes in the era of therapeutic hypothermia

Vincent Jahandiez , Bruno Pillot , Gabriel Bidaux , Radu Bolbos , Neven Stevic
Translational Research, The Journal of Laboratory and Clinical Medicine, 2022, 249, pp.37-48. ⟨10.1016/j.trsl.2022.06.006⟩
Article dans une revue hal-03704281v1
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Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

Matthieu Chourrout , Hugo Rositi , Elodie Ong , Violaine Hubert , Alexandre Paccalet
Biomedical optics express, 2022, 13 (3), pp.1620-1639. ⟨10.1364/BOE.438832⟩
Article dans une revue hal-03428448v2
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Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke

Chloé Dumot , Chrystelle Po , Lucille Capin , Violaine Hubert , Elodie Ong
Scientific Reports, 2022, 12, pp.4700. ⟨10.1038/s41598-022-08713-z⟩
Article dans une revue hal-03451443v2
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Brain virtual histology with X-ray phase-contrast tomography Part II: 3D morphologies of amyloid-β plaques in Alzheimer’s disease models

Matthieu Chourrout , Margaux Roux , Carlie Boisvert , Coralie Gislard , David Legland
Biomedical optics express, 2022, 13 (3), pp.1640-1653. ⟨10.1364/BOE.438890⟩
Article dans une revue hal-03451419v2
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Hybrid Multimodal Contrast Agent for Multiscale In Vivo Investigation of Neuroinflammation

Szilvia Karpati , Violaine Hubert , Ines Hristova , Frederic Lerouge , Fréderic Chaput
Nanoscale, 2021, ⟨10.1039/D0NR07026B⟩
Article dans une revue hal-03134034v1
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Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke

Violaine Hubert , Ines Hristovska , Szilvia Karpati , Sarah Benkeder , Arindam Dey
Advanced Science, 2021, 8 (17), pp.2101433. ⟨10.1002/advs.202101433⟩
Article dans une revue hal-03428486v1
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Contribution of preclinical MRI to responsible animal research: living up to the 3R principle

Lydia Wachsmuth , Armand Mensen , Cristina Barca , Marlene Wiart , Catarina Tristão-Pereira
Magnetic Resonance Materials in Physics, Biology and Medicine, 2021, 34 (4), pp.469-474. ⟨10.1007/s10334-021-00929-w⟩
Article dans une revue hal-03264434v1
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Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage

Elisa Cuccione , Peter Chhour , Salim Si-Mohamed , Chloé Dumot , Johoon Kim
Nanotheranostics, 2020, 4 (3), pp.129-141. ⟨10.7150/ntno.45354⟩
Article dans une revue hal-02841219v1
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PET-MRI nanoparticles imaging of blood–brain barrier damage and modulation after stroke reperfusion

Justine Debatisse , Omer Faruk Eker , Océane Wateau , Tae-Hee Cho , Marlene Wiart
Brain Communications, 2020, 2 (2), ⟨10.1093/braincomms/fcaa193⟩
Article dans une revue hal-03060618v1
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Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study

Maryna Basalay , Marlene Wiart , Fabien Chauveau , Chloe Dumot , Christelle Leon
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-74046-4⟩
Article dans une revue hal-02964076v1
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Clinical imaging of choroid plexus in health and in brain disorders: a mini-review

V. Hubert , Fabien Chauveau , C. Dumot , E. Ong , L. P. Berner
Frontiers in Molecular Neuroscience, 2019, 12, pp.34. ⟨10.3389/fnmol.2019.00034⟩
Article dans une revue hal-02195240v1
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MRI coupled with clinically-applicable iron oxide nanoparticles reveals choroid plexus involvement in a murine model of neuroinflammation

Violaine Hubert , Chloé Dumot , Elodie Ong , Camille Amaz , Emmanuelle Canet-Soulas
Scientific Reports, 2019, 9 (1), pp.1-9. ⟨10.1038/s41598-019-46566-1⟩
Article dans une revue hal-02397061v1

INFLAM - INFLAMmation in brain and vessels with iron nanoparticles and cell trafficking: A multiscale approach of tissue microenvironment, iron nanostructure and iron biotransformation

Jean-Christophe Brisset , F. Gazeau , C. Corot , Norbert Nighoghossian , Y. Berthezène
Innovation and Research in BioMedical engineering, 2018, 39 (2), pp.93-102. ⟨10.1016/j.irbm.2018.02.002⟩
Article dans une revue hal-02626355v1

X-ray-Based 3D Virtual Histology—Adding the Next Dimension to Histological Analysis

J. Albers , S. Pacilé , M. Lynne Markus , M. Wiart , G. Vande Velde
Molecular Imaging and Biology, 2018, 20 (5), pp.732-741. ⟨10.1007/s11307-018-1246-3⟩
Article dans une revue hal-02397068v1

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protectionevaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

S. M. Davidson , S. Arjun , M. V. Basalay , R. M. Bell , D. I. Bromage
Basic Research in Cardiology, 2018, 113 (6), pp.11
Article dans une revue hal-02003429v1

INFLAM - INFLAMmation in Brain and Vessels with Iron Nanoparticles and Cell Trafficking: A Multiscale Approach of Tissue Microenvironment, Iron Nanostructure and Iron Biotransformation

J. C. Brisset , F. Gazeau , C. Corot , N. Nighoghossian , Y. Berthezene
Innovation and Research in BioMedical engineering, 2018, 39 (2), pp.93-102
Article dans une revue hal-01847414v1

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

Sean Davidson , Sapna Arjun , Maryna Basalay , Robert Bell , Daniel Bromage
Basic Research in Cardiology, 2018, 113 (6), ⟨10.1007/s00395-018-0704-z⟩
Article dans une revue hal-02397066v1

Ferritin surplus in mouse spleen 14 months after intravenous injection of iron oxide nanoparticles at clinical dose

Alexandre Tamion , Matthias Hillenkamp , Arnaud Hillion , Valentin A. Maraloiu , Ioana D. Vlaicu
Nano Research, 2016, 9, pp.2398-2410. ⟨10.1007/s12274-016-1126-6⟩
Article dans une revue hal-02289463v1
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Multi-site laser Doppler flowmetry for assessing collateral flow in experimental ischemic stroke: Validation of outcome prediction with acute MRI

Elisa Cuccione , Alessandro Versace , Tae-Hee Cho , Davide Carone , Lise-Prune Berner
Journal of Cerebral Blood Flow and Metabolism, 2016, 37 (6), pp.2159-2170. ⟨10.1177/0271678X16661567⟩
Article dans une revue hal-02308993v1

Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE−/− Mice

Vanessa Di Cataldo , Alain Geloen , Jean-Baptiste Langlois , Fabien Chauveau , Benoît Thézé
Frontiers in Physiology, 2016, 7, ⟨10.3389/fphys.2016.00453⟩
Article dans une revue hal-01883954v1
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Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE-/- Mice

V. Di Cataldo , A. Geloen , J. B. Langlois , F. Chauveau , B. Theze
Frontiers in Physiology, 2016, 7, pp.453. ⟨10.3389/fphys.2016.00453⟩
Article dans une revue hal-01850301v1

Validity of Shape as a Predictive Biomarker of Final Infarct Volume in Acute Ischemic Stroke

C. Frindel , A. Rouanet , M. Giacalone , T.-H. Cho , L. Østergaard
Stroke, 2015, 46, pp.976-998. ⟨10.1161/STROKEAHA.114.008046⟩
Article dans une revue hal-01131822v1

Effects of a TAFI-inhibitor combined with a suboptimal dose of rtPA in a murine thromboembolic model of stroke

A. Durand , F. Chauveau , T. H. Cho , C. Kallus , M. Wagner
Cerebrovascular Diseases, 2014, 38, pp.268-75. ⟨10.1159/000366266⟩
Article dans une revue hal-02071538v1

Computer vision tools to optimize reconstruction parameters in x-ray in-line phase tomography.

H. Rositi , C. Frindel , M. Wiart , M. Langer , Cécile Olivier
Physics in Medicine and Biology, 2014, 59 (24), pp.7767-7775. ⟨10.1088/0031-9155/59/24/7767⟩
Article dans une revue hal-01115012v1

MRI assessment of the intra-carotid route for macrophage delivery after transient cerebral ischemia

Agathe Riou , F. Chauveau , T.-H. Cho , M. Marinescu , S. Nataf
NMR in Biomedicine, 2013, 26 (2), pp.115-123. ⟨10.1002/nbm.2826⟩
Article dans une revue hal-00797986v1
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Information-based analysis of X-ray in-line phase tomography with application to the detection of iron oxide nanoparticles in the brain

H. Rositi , C. Frindel , M. Langer , M. Wiart , Cécile Olivier
Optics Express, 2013, 21 (22), pp.27185-27196. ⟨10.1364/OE.21.027185⟩
Article dans une revue hal-00951410v1

Synchrotron Radiation X-Ray Phase Micro-computed Tomography as a New Method to Detect Iron Oxide Nanoparticles in the Brain

M. Marinescu , M. Langer , A. Durand , Cécile Olivier , A. Chabrol
Molecular Imaging and Biology, 2013, 15 (5), pp.552-559. ⟨10.1007/s11307-013-0639-6⟩
Article dans une revue hal-00821105v1

Pre- and post-treatment with cyclosporine A in a rat model of transient focal cerebral ischaemia with multimodal MRI screening

Tae-Hee Cho , Pierre Aguettaz , Oscar Campuzano , Christiane Charriaut-Marlangue , Adrien Riou
International Journal of Stroke, 2013, 8 (8), pp.669-674. ⟨10.1111/j.1747-4949.2012.00849.x⟩
Article dans une revue hal-00798015v1
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In Vitro and In Vivo Models of Cerebral Ischemia Show Discrepancy in Therapeutic Effects of M2 Macrophages

Virginie Desestret , Adrien Riou , Fabien Chauveau , Tae-Hee Cho , Emilie Devillard
PLoS ONE, 2013, 8 (6), pp.e67063. ⟨10.1371/journal.pone.0067063⟩
Article dans une revue hal-00871768v1

Monitoring therapeutic effects in experimental stroke by serial USPIO-enhanced MRI

M. Marinescu , F. Chauveau , A. Durand , Agathe Riou , T.-H. Cho
European Radiology, 2012, 23 (1), pp.37-47. ⟨10.1007/s00330-012-2567-2⟩
Article dans une revue hal-00797957v1

Brain-Targeting Form of Docosahexaenoic Acid for Experimental Stroke Treatment: MRI Evaluation and Anti-Oxidant Impact

Fabien Chauveau , Tae-Hee Cho , Magali Perez , Michel Guichardant , Adrien Riou
Current Neurovascular Research, 2011, 8 (2), pp.95 - 102
Article dans une revue hal-02653073v1

Quantification of iron-labeled cells with positive contrast in mouse brains

J. C. Brisset , M. Sigovan , F. Chauveau , Agathe Riou , E. Devillard
Mol Imaging Biol, 2011, 13 (4), pp.672--678
Article dans une revue hal-02076422v1
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In vivo MRI assessment of permanent middle cerebral artery occlusion by electrocoagulation: pitfalls of procedure

Fabien Chauveau , Samir Moucharrafie , Marlène Wiart , Jean-Christophe Brisset , Yves Berthezène
Experimental & Translational Stroke Medicine, 2010, 2 (1), pp.4. ⟨10.1186/2040-7378-2-4⟩
Article dans une revue inserm-00663532v1

Early stage investigations of USPIO-induced signal changes after focal cerebral ischemia in mice

V. Desestret , J. C. Brisset , E. Devillard , S. Moucharrafie , S. Nataf
Stroke, 2009, 40, pp.1834-1841
Article dans une revue hal-00443229v1

Quantitative effects of cell internalization of two types of ultrasmall superparamagnetic iron oxide nanoparticles at 4.7T and 7T

J. C. Brisset , V. Desestret , E. Devillard , S. Marcellino , F. Chauveau
Eur Radiol, 2009, in-press
Article dans une revue hal-00443170v1

Characterization of hepatocellular carcinoma and colorectal liver metastasis by means of perfusion MRI

S. Abdullah , J. B. Pialat , M. Wiart , F. Duboeuf , J. Y. Mabrut
Journal of Magnetic Resonance Imaging, 2008, 28 (2), pp.544-546
Article dans une revue hal-00443063v1

Novel Applications of Magnetic Resonance Imaging to Image Tissue Inflammation after Stroke

N. Nighoghossian , M. Wiart , Y. Berthezène
J Neuroimaging, 2008, 28 (2), pp.390-395
Article dans une revue hal-00443377v1

Magnetic resonance imaging (MRI) of inflammation in stroke

M. Wiart , N. Davoust , J. B. Pialat , Y. Berthezène , N. Nighoghossian
Conf Proc IEEE Eng Med Biol Soc, 2007, 2007, pp.(4316-9)
Article dans une revue hal-00443497v1

MRI monitoring of focal cerebral ischemia in peroxisome proliferator-activated receptor (PPAR)-deficient mice

J. B. Pialat , T. H. Cho , O. Beuf , S. Moucharrafie , J. B. Langlois
Nuclear Magnetic Resonance in Biomedicine, 2007, 20 (3), pp.335-342
Article dans une revue hal-00443396v1

Response to Letter by Bendszus, Kleinschnitz and Stoll: Iron-enhanced MRI in ischemic stroke: intravascular trapping vs cellular imaging

M. Wiart , N. Davoust , V. Desestret , N. Nighoghossian , Y. Berthezène
Stroke, 2007, 38, pp.13
Article dans une revue hal-00443496v1

Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients

N. Nighoghossian , M. Wiart , S. Cakmak , Y. Berthezène , L. Derex
Stroke, 2007, 38 (2), pp.303-307
Article dans une revue hal-00443378v1

Influence of perfusion on high-intensity focused ultrasound prostate ablation: a first-pass MRI study.

Marlène Wiart , Laura Curiel , Albert Gelet , Denis Lyonnet , Jean-Yves Chapelon
Magnetic Resonance in Medicine, 2007, 58 (1), pp.119-27. ⟨10.1002/mrm.21271⟩
Article dans une revue hal-00399060v1

USPIO-enhanced MRI of neuroinflammation at the sub-acute stage of ischemic stroke, preliminary data

T. H. Cho , N. Nighoghossian , M. Wiart , V. Desestret , S. Cakmak
Cerebrovascular Diseases, 2007, 24 (6), pp.544-546
Article dans une revue hal-00443192v1

MRI monitoring of neuro-inflammation in mouse focal ischemia

M. Wiart , N. Davoust , J. B. Pialat , V. Desestret , S. Moucharrafie
Stroke, 2007, 38 (1), pp.131-137
Article dans une revue hal-00443499v1

In vivo quantification of regional myocardial blood flow: Validity of the fast exchange approximation for intravascular T1 contrast agent and long inversion time

M. Wiart , S. Carme , W. Mai , H. Larsson , B. Neyran
Magnetic Resonance in Medicine, 2006, 56 (2), pp.39-40
Article dans une revue hal-00443494v1

CMR 2005: MRI of cerebral ischemia with ultra-small superparamagnetic particles of iron oxide in mice

M. Wiart , N. Davoust , J. B. Pialat , V. Desestret , S. Moucharrafie
Contrast Media and Molecular Imaging, 2006, 1 (2), pp.55-56
Article dans une revue hal-00443498v1

Importance of parametric mapping and deconvolution in analyzing MR myocardial perfusion images

S. Carme , W. Mai , M. Janier , D. Revel , I. E. Magnin
Investigative Radiology, 2006, 41 (4), pp.374-383
Article dans une revue hal-00443180v1

Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator

L. Derex , M. Hermier , P. Adeleine , J.B. Pialat , M. Wiart
Journal of Neurology, Neurosurgery and Psychiatry, 2005, 76, pp.70-75
Article dans une revue hal-00427740v1

Hypointense leptomeningeal vessels at T2*-weighted MRI in acute ischemic stroke

M. Hermier , N. Nighoghossian , L. Derex , M. Wiart , C. Nemoz
Neurology, 2005, 65, pp.652-653
Article dans une revue hal-00443278v1

Evolution of lesion volume in acute stroke treated by intravenous t-PA

J.B. Pialat , M. Wiart , N. Nighoghossian , P. Adeleine , L. Derex
Journal of Magnetic Resonance Imaging, 2005, 22, pp.23-28
Article dans une revue hal-00427844v1

Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator

L. Derex , M. Hermier , P. Adeleine , J. B. Pialat , M. Wiart
Journal of Neurology, Neurosurgery and Psychiatry, 2005, 76, pp.70-75
Article dans une revue hal-00443225v1

Evolution of Lesion Volume in Acute Stroke Treated by Intravenous t-PA

J. B. Pialat , M. Wiart , N. Nighoghossian , P. Adeleine , L. Derex
J Magn Reson Imaging, 2005, 22, pp.23-28
Article dans une revue hal-00443398v1

Influence of the site of arterial occlusion on multiple baseline hemodynamic MRI parameters and post-thrombolytic recanalization in acute stroke

L. Derex , M. Hermier , P. Adeleine , J.B. Pialat , M. Wiart
Neuroradiology, 2004, 46, pp.883-887
Article dans une revue hal-00427576v1

Magnetic Resonance Imaging: Significance of Early Ischemic Changes on Computed Tomography

L. Derex , N. Nighoghossian , M. Hermier , J.B. Pialat , M. Wiart
Cerebrovascular Diseases, 2004, 18, pp.232-235
Article dans une revue hal-00427574v1

Hypointense transcerebral veins at T2*-weighted MRI: A marker of hemorrhagic transformation risk in patients treated with intravenous tissue plasminogen activator

M. Hermier , N. Nighoghossian , L. Derex , P. Adeleine , M. Wiart
Journal of Cerebral Blood Flow and Metabolism, 2003, 23, pp.1362-1370
Article dans une revue hal-00427435v1

The delayed perfusion sign at MRI - A potential marker of collateral leptomeningeal blood flow in acute stroke

M. Hermier , A.S. Ibrahim , M. Wiart , P. Adeleine , F. Cotton
Journal de Neuroradiologie / Journal of Neuroradiology, 2003, 30, pp.172-179
Article dans une revue hal-00427434v1