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Le déficit en alpha-1-antitrypsine

Marion Bouchecareilh
Médecine/Sciences, 2014, 30 (10), pp.889-895. ⟨10.1051/medsci/20143010016⟩
Article dans une revue hal-02400339v1
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The Autophagy Pathway: A Critical Route in the Disposal of Alpha 1-Antitrypsin Aggregates That Holds Many Mysteries

Celine Leon , Marion Bouchecareilh
International Journal of Molecular Sciences, 2021, 22 (4), pp.1875. ⟨10.3390/ijms22041875⟩
Article dans une revue hal-03436316v1
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Measuring the Effect of Histone Deacetylase Inhibitors (HDACi) on the Secretion and Activity of Alpha-1 Antitrypsin.

Chao Wang , Marion Bouchecareilh , William Balch
Alpha-1 Antitrypsin Deficiency, pp.185-193, 2017, ⟨10.1007/978-1-4939-7163-3_18⟩
Chapitre d'ouvrage hal-02400293v1

The Histone Deacetylase Inhibitor, Vorinostat, Represses Hypoxia Inducible Factor 1 Alpha Expression through Translational Inhibition

Darren Hutt , Daniela Martino Roth , Hélène Vignaud , Christophe Cullin , Marion Bouchecareilh
PLoS ONE, 2014, 9 (8), pp.e106224. ⟨10.1371/journal.pone.0106224⟩
Article dans une revue hal-02400346v1
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Protease-antiprotease imbalance in patients with severe COVID-19

Farid Zerimech , Merce Jourdain , Brigitte Onraed , Marion Bouchecareilh , Boualem Sendid , et al.
Clinical Chemistry and Laboratory Medicine, 2021, 59 (8), pp.e330-e334. ⟨10.1515/cclm-2021-0137⟩
Article dans une revue hal-03436312v1

Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation

Darren Hutt , Daniela Martino Roth , Christelle Marchal , Marion Bouchecareilh
HDAC/HAT Function Assessment and Inhibitor Development, pp.77-91, 2017, ⟨10.1007/978-1-4939-6527-4_6⟩
Chapitre d'ouvrage hal-02400309v1

Histone Deacetylase Inhibitor (HDACi) Suberoylanilide Hydroxamic Acid (SAHA)-mediated Correction of α1-Antitrypsin Deficiency

Marion Bouchecareilh , Darren Hutt , Patricia Szajner , Terence Flotte , William Balch
Journal of Biological Chemistry, 2012, 287 (45), pp.38265-38278. ⟨10.1074/jbc.M112.404707⟩
Article dans une revue hal-02400362v1

Strain differences in hypothalamic —pituitary— adrenocortical axis function and adipogenic effects of corticosterone in rats

N. Marissal-Arvy , Adrien Gaumont , A. Langlois , F. Dabertrand , M. Bouchecareilh , et al.
Journal of Endocrinology, 2007, 195 (3), pp.473-484. ⟨10.1677/JOE-07-0077⟩
Article dans une revue hal-02664515v1
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A Particular SORL1 Micro-haplotype May Prevent Severe Liver Disease in a French Cohort of Alpha 1-Antitrypsin-deficient Children

Philippe Joly , Mathias Ruiz , Roman Garin , Esra Karatas , Alain Lachaux , et al.
Journal of Pediatric Gastroenterology and Nutrition, 2021, 73 (3), pp.e68-e72. ⟨10.1097/MPG.0000000000003125⟩
Article dans une revue hal-03436289v1
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Overview of Alpha-1 Antitrypsin Deficiency- Mediated Liver Disease

Esra Karatas , Sylvaine Di-Tommaso , Nathalie Dugot-Senant , Alain Lachaux , Marion Bouchecareilh
European Medical Journal, 2019
Article dans une revue hal-02388724v1
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CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine

Antoine Dewitte , Julien Villeneuve , Sébastien Lepreux , Marion Bouchecareilh , Xavier Gauthereau , et al.
Mediators of Inflammation, 2020, 2020, pp.6357046. ⟨10.1155/2020/6357046⟩
Article dans une revue inserm-02870964v1
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Alpha-1 Antitrypsin Deficiency-Mediated Liver Toxicity: Why Do Some Patients Do Poorly? What Do We Know So Far?

Marion Bouchecareilh
Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, 2020, 7 (3), pp.172-181. ⟨10.15326/jcopdf.7.3.2019.0148⟩
Article dans une revue hal-03014660v1

Proteostasis, an Emerging Therapeutic Paradigm for Managing Inflammatory Airway Stress Disease

M. Bouchecareilh , W. E. Balch
Current Molecular Medicine, 2012, 12 (7), pp.815-826. ⟨10.2174/156652412801318782⟩
Article dans une revue hal-02400388v1
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Hepatocyte proteomes reveal the role of protein disulfide isomerase 4 in alpha 1-antitrypsin deficiency

Esra Karatas , Anne-Aurélie Raymond , Céline Leon , Jean-William Dupuy , Sylvaine Di-Tommaso , et al.
JHEP Reports Innovation in Hepatology, 2021, 3 (4), pp.100297. ⟨10.1016/j.jhepr.2021.100297⟩
Article dans une revue hal-03436286v1
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The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A.

Sophie Dedieu , Xavier Canron , Hamid Reza Rezvani , Marion Bouchecareilh , Frédéric Mazurier , et al.
BMC Medicine, 2010, 8 (1), pp.19. ⟨10.1186/1741-7015-8-19⟩
Article dans une revue inserm-00663906v1
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Alpha 1-Antitrypsin deficiency in liver explants in a Mexican cohort: A unique cohort to assess the role of heterozygous genotypes in liver disease

E. Karatas , M. Bouchecareilh
Clinics and Research in Hepatology and Gastroenterology, 2021, 45 (3), pp.101538. ⟨10.1016/j.clinre.2020.09.003⟩
Article dans une revue hal-03014657v1
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Alpha 1-Antitrypsin Deficiency: A Disorder of Proteostasis-Mediated Protein Folding and Trafficking Pathways

Esra Karatas , Marion Bouchecareilh
International Journal of Molecular Sciences, 2020, 21 (4), pp.1493. ⟨10.3390/ijms21041493⟩
Article dans une revue hal-03014663v1

Role of Pro-oncogenic Protein Disulfide Isomerase (PDI) Family Member Anterior Gradient 2 (AGR2) in the Control of Endoplasmic Reticulum Homeostasis

Arisa Higa , Audrey Mulot , Frederic Delom , Marion Bouchecareilh , Duc Thang Nguyên , et al.
Journal of Biological Chemistry, 2011, 286 (52), pp.44855-44868. ⟨10.1074/jbc.M111.275529⟩
Article dans une revue hal-02400392v1

Liver disease related to alpha1-antitrypsin deficiency in French children: The DEFI-ALPHA cohort

M. Ruiz , F. Lacaille , J. Berthiller , P. Joly , J. Dumortier , et al.
Liver International, 2019, 39 (6), pp.1136--1146. ⟨10.1111/liv.14035⟩
Article dans une revue hal-02195200v1

SERPINA1 and MAN1B1 polymorphisms are not linked to severe liver disease in a French cohort of alpha-1 antitrypsin deficiency children

Philippe Joly , Alain Lachaux , Mathias Ruiz , Lioara Restier , Abdelhouaed Belmalih , et al.
Liver International, 2017, 37 (11), pp.1608-1611. ⟨10.1111/liv.13586⟩
Article dans une revue hal-02329718v1

Autocrine control of glioma cells adhesion and migration through IRE1 -mediated cleavage of SPARC mRNA

N. Dejeans , O. Pluquet , S. Lhomond , F. Grise , M. Bouchecareilh , et al.
Journal of Cell Science, 2012, 125 (18), pp.4278-4287. ⟨10.1242/jcs.099291⟩
Article dans une revue hal-02400377v1

Le déficit en alpha-1 antitrypsine : modèle d’altération de l’homéostasie protéique ou protéostasie

H. Vignaud , C. Cullin , M. Bouchecareilh
Revue des Maladies Respiratoires, 2015, 32 (10), pp.1059-1071. ⟨10.1016/j.rmr.2015.05.013⟩
Article dans une revue hal-02400318v1

ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency

Philippe Joly , Hélène Vignaud , Julie Di Martino , Mathias Ruiz , Roman Garin , et al.
PLoS ONE, 2017, 12 (6), pp.e0179369. ⟨10.1371/journal.pone.0179369⟩
Article dans une revue hal-02329741v1

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1  expression through translational inhibition.

Dm Hutt , Dm Roth , H Vignaud , C Cullin , M Bouchecareilh
PLoS ONE, 2014, 9 (8), pp.e106224
Article dans une revue hal-01074772v1
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Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia

Tra Ly Nguyen , Marie‐julie Nokin , Silvia Terés , Mercedes Tomé , Clément Bodineau , et al.
Molecular Oncology, 2021, 15, pp.1412 - 1431. ⟨10.1002/1878-0261.12877⟩
Article dans une revue hal-03408341v1

Posttranscriptional Regulation of PER1 Underlies the Oncogenic Function of IRE

O. Pluquet , N. Dejeans , M. Bouchecareilh , S. Lhomond , R. Pineau , et al.
Cancer Research, 2013, 73 (15), pp.4732-4743. ⟨10.1158/0008-5472.CAN-12-3989⟩
Article dans une revue hal-02400356v1

Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

Daniela Martino Roth , Darren Hutt , Jiansong Tong , Marion Bouchecareilh , Ning Wang , et al.
PLoS Biology, 2014, 12 (11), pp.e1001998. ⟨10.1371/journal.pbio.1001998⟩
Article dans une revue hal-02400334v1

Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis

Frédéric Larrieu-Lahargue , Alana Welm , Marion Bouchecareilh , Kari Alitalo , Dean Li , et al.
PLoS ONE, 2012, 7 (6), pp.e39540. ⟨10.1371/journal.pone.0039540⟩
Article dans une revue hal-02400367v1

Cohorte DEFI-ALPHA et projet hospitalier de recherche clinique POLYGEN DEFI-ALPHA. Étude des facteurs cliniques, biologiques et génétiques associés à l’apparition et à l’évolution de complications hépatiques chez les enfants présentant un déficit en alpha-1 antitrypsine

Philippe Joly , L. Restier , M. Bouchecareilh , P. Lacan , F. Cabet , et al.
Revue des Maladies Respiratoires, 2015, 32 (7), pp.759-767. ⟨10.1016/j.rmr.2015.06.010⟩
Article dans une revue hal-02363870v1

mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation

Victor Villar , Tra Ly Nguyen , Vanessa Delcroix , Silvia Terés , Marion Bouchecareilh , et al.
Nature Communications, 2017, 8 (1), ⟨10.1038/ncomms14124⟩
Article dans une revue hal-02400301v1