Marie Lopez

João Lobo, Ana Rita Cardoso, Vera Miranda-Gonçalves, Leendert H J Looijenga, Marie Lopez, et al.. Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest. Pharmaceutics, MDPI, 2021, Special Issue Cancer Mechanisms and Emerging Therapies, 13 (1), pp.73. ⟨10.3390/pharmaceutics13010073⟩. ⟨pasteur-03105846⟩

Nelia Luviano, Marie Lopez, Fleur Gawehns, Cristian Chaparro, Paola B Arimondo, et al.. The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor. Epigenetics & Chromatin, BioMed Central, 2021, 14 (1), pp.48. ⟨10.1186/s13072-021-00422-7⟩. ⟨pasteur-03427775v2⟩

Ângela Marques-Magalhães, Inês Graça, Vera Miranda-Gonçalves, Rui Henrique, Marie Lopez, et al.. Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines. Biomedicine and Pharmacotherapy, Elsevier, 2021, 141, pp.111681. ⟨10.1016/j.biopha.2021.111681⟩. ⟨pasteur-03411793⟩

Dany Pechalrieu, Daniel Dauzonne, Paola Arimondo, Marie Lopez. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. European Journal of Medicinal Chemistry, Elsevier, 2020, pp.111829. ⟨10.1016/j.ejmech.2019.111829⟩. ⟨hal-02394113⟩

Dany Pechalrieu, Fanny Assemat, Ludovic Halby, Marlene Marcellin, Pengrong yan, et al.. Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs. ACS Chemical Biology, American Chemical Society, 2020, 15 (4), pp.952-961. ⟨10.1021/acschembio.9b00965⟩. ⟨pasteur-03026521⟩

Marie Lopez, Jeremy Choin, Martin Sikora, Katherine Siddle, Christine Harmant, et al.. Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest. Current Biology - CB, Elsevier, 2019, ⟨10.1016/j.cub.2019.07.013⟩. ⟨hal-02271461⟩

Marie Lopez, Athanasios Kousathanas, Hélène Quach, Christine Harmant, Patrick Mouguiama-Daouda, et al.. The demographic history and mutational load of African hunter-gatherers and farmers. Nature Ecology & Evolution, Nature, 2018, 2 (4), pp.721-730. ⟨10.1038/s41559-018-0496-4⟩. ⟨hal-02271464⟩

Santiago Lascano, Marie Lopez, Paola B Arimondo. Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers. Chemical Record, Chemical Society of Japan, 2018, 18 (12), pp.1854-1876. ⟨10.1002/tcr.201800133⟩. ⟨hal-03082748⟩

Etienne Patin, Marie Lopez, Rebecca Grollemund, Paul Verdu, Christine Harmant, et al.. Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.. Science, American Association for the Advancement of Science (AAAS), 2017, 356 (6337), pp.543-546. ⟨10.1126/science.aal1988⟩. ⟨hal-02277558⟩

Dany Pechalrieu, Marie Lopez. Compounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1). Expert Opinion on Therapeutic Patents, Informa Healthcare, 2015, 25 (6), pp.729-735. ⟨10.1517/13543776.2015.1021333⟩. ⟨hal-02399895⟩

Marie Lopez, Laurent Bornaghi, Sally-Ann Poulsen. Synthesis of sulfonamide-conjugated glycosyl-amino acid building blocks. Carbohydrate Research, Elsevier, 2014, 386, pp.78-85. ⟨10.1016/j.carres.2013.08.017⟩. ⟨hal-03130488⟩

Katia d'Ambrosio, Marie Lopez, Nina Dathan, Safia Ouahrani-Bettache, Stephan Köhler, et al.. Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis. Biochimie, Elsevier, 2014, 97, pp.114-120. ⟨10.1016/j.biochi.2013.09.028⟩. ⟨hal-02425093⟩

François Turtaut, Marie Lopez, Safia Ouahrani-Bettache, Stephan Köhler, Jean-yves Winum. Oxo- and thiooxo-imidazo[1,5-c]pyrimidine molecule library: Beyond their interest in inhibition of Brucella suis histidinol dehydrogenase, a powerful protection tool in the synthesis of histidine analogues. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩. ⟨hal-02425098⟩

Katherine Andrews, Gillian Fisher, Subathdrage D.M. Sumanadasa, Tina Skinner-Adams, Janina Moeker, et al.. Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment. Bioorganic & Medicinal Chemistry Letters, 2013, 23 (22), pp.6114-6117. ⟨10.1016/j.bmcl.2013.09.015⟩. ⟨hal-03130480⟩

Cindy Carroux, Janina Moeker, Josephine Motte, Marie Lopez, Laurent Bornaghi, et al.. Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties. Bioorganic & Medicinal Chemistry Letters, 2013, 23 (2), pp.455-459. ⟨10.1016/j.bmcl.2012.11.056⟩. ⟨hal-03130067⟩

Janina Moeker, Kanae Teruya, Sabine Rossit, Brendan Wilkinson, Marie Lopez, et al.. Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases. Bioorganic & Medicinal Chemistry Letters, 2012, 20 (7), pp.2392-2404. ⟨10.1016/j.bmc.2012.01.052⟩. ⟨hal-03130049⟩

Marie Lopez, Sébastien Fort, Herve Bizot, Alain Buléon, Hugues Driguez. Chemo-enzymatic synthesis of xylogluco-oligosaccharides and their interactions with cellulose. Carbohydrate Polymers, Elsevier, 2012, 88 (1), pp.185-193. ⟨10.1016/j.carbpol.2011.11.085⟩. ⟨hal-02119250⟩

Marie Lopez, Stephan Köhler, Jean-yves Winum. Zinc metalloenzymes as new targets against the bacterial pathogen Brucella. Journal of Inorganic Biochemistry, Elsevier, 2012, 111, pp.138-145. ⟨10.1016/j.jinorgbio.2011.10.019⟩. ⟨hal-02424989⟩

Marie Lopez, Laurent Bornaghi, Hugues Driguez, Sally-Ann Poulsen. Synthesis of Sulfonamide-Bridged Glycomimetics. Journal of Organic Chemistry, American Chemical Society, 2011, 76 (9), pp.2965-2975. ⟨10.1021/jo2001269⟩. ⟨hal-03129918⟩

Marie Lopez, Hoan Vu, Conan Wang, Maarten Wolf, Gerrit Groenhof, et al.. Promiscuity of Carbonic Anhydrase II. Unexpected Ester Hydrolysis of Carbohydrate-Based Sulfamate Inhibitors. Journal of the American Chemical Society, American Chemical Society, 2011, 133 (45), pp.18452-18462. ⟨10.1021/ja207855c⟩. ⟨hal-03129971⟩

Marie Lopez, Jonathan Trajkovic, Laurent Bornaghi, Alessio Innocenti, Daniela Vullo, et al.. Design, Synthesis, and Biological Evaluation of Novel Carbohydrate-Based Sulfamates as Carbonic Anhydrase Inhibitors. Journal of Medicinal Chemistry, American Chemical Society, 2011, 54 (5), pp.1481-1489. ⟨10.1021/jm101525j⟩. ⟨hal-03129906⟩

Jason C Morris, Johanna Chiche, Caroline Grellier, Marie Lopez, Laurent F Bornaghi, et al.. Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.. Journal of Medicinal Chemistry, American Chemical Society, 2011, 54 (19), pp.6905-18. ⟨10.1021/jm200892s⟩. ⟨hal-00756639⟩

Marie Lopez, Adam J. Salmon, Claudiu T. Supuran, Sally-Ann Poulsen. Carbonic Anhydrase Inhibitors Developed Through "Click Tailing". Current Pharmaceutical Design, Bentham Science Publishers, 2010, 16 (29), pp.3277-3287. ⟨10.2174/138161210793429869⟩. ⟨hal-03129902⟩

Brendan L. Wilkinson, Laurent F Bornaghi, Marie Lopez, Peter C. Healy, Sally-Ann Poulsen, et al.. Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry. Australian Journal of Chemistry, CSIRO Publishing, 2010, 63 (5), pp.821. ⟨10.1071/CH09426⟩. ⟨hal-03129177⟩

Marie Lopez, Laurent F Bornaghi, Alessio Innocenti, Daniela Vullo, Susan A. Charman, et al.. Sulfonamide Linked Neoglycoconjugates−A New Class of Inhibitors for Cancer-Associated Carbonic Anhydrases. Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (7), pp.2913-2926. ⟨10.1021/jm901888x⟩. ⟨hal-03128749⟩

Mathilde Singer, Marie Lopez, Laurent F Bornaghi, Alessio Innocenti, Daniela Vullo, et al.. Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties. Bioorganic & Medicinal Chemistry Letters, 2009, 19 (8), pp.2273-2276. ⟨10.1016/j.bmcl.2009.02.086⟩. ⟨hal-03128552⟩

Marie Lopez, Nicolas Drillaud, Laurent F Bornaghi, Sally-Ann Poulsen. Synthesis of S -Glycosyl Primary Sulfonamides. Journal of Organic Chemistry, American Chemical Society, 2009, 74 (7), pp.2811-2816. ⟨10.1021/jo9000367⟩. ⟨hal-03128559⟩

Marie Lopez, Blessy Paul, Andreas Hoffmann, Julia Morizzi, Quoc K. Wu, et al.. S -Glycosyl Primary Sulfonamides−A New Structural Class for Selective Inhibition of Cancer-Associated Carbonic Anhydrases. Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (20), pp.6421-6432. ⟨10.1021/jm900914e⟩. ⟨hal-03128575⟩

Marie Lopez, C.R. Altabla, Thierry Rouault, E. Gisbert. The European Sturgeon Acipenser sturio is a suitable host for the glochidia of the freshwater pearl mussel Margaritifera auricularia. Journal of Molluscan Studies, Oxford University Press (OUP), 2007, 73, pp.207-209. ⟨hal-02589551⟩

Kathleen Piens, Anna-Maria Henriksson, Fredrika Gullfot, Marie Lopez, Régis Fauré, et al.. Glycosynthase activity of hybrid aspen xyloglucan endo-transglycosylase PttXET16-34 nucleophile mutants.. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2007, 5 (24), pp.3971-8. ⟨10.1039/b714570e⟩. ⟨hal-00623924⟩

Marie Lopez, Ludovic Halby, Paola Arimondo. DNA Methyltransferase Inhibitors: Development and Applications. DNA Methyltransferases - Role and Function, pp.431-473, 2016, ⟨10.1007/978-3-319-43624-1_16⟩. ⟨hal-02399858⟩

Marie Lopez, Maxime Leroy, Chantal Etiévant, Frédéric Ausseil, Alexandre Gagnon, et al.. Drug Discovery Methods. Drug Discovery in Cancer Epigenetics, Elsevier, pp.63-95, 2016, ⟨10.1016/b978-0-12-802208-5.00003-5⟩. ⟨hal-02399880⟩

Marie Lopez. Hydrolyses et Synthèse chimio-enzymatiques appliquées à la préparation de xyloglucooligosaccharides pour l'étude des interactions xyloglucanes-cellulose. Chimie. Université Joseph-Fourier - Grenoble I, 2007. Français. ⟨tel-00420010⟩