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Generation and CRISPR/Cas9 editing of transformed progenitor B cells as a pseudo-physiological system to study DNA repair gene function in V(D)J recombination

Hélène Lenden Hasse , Chloé Lescale , Joy J. Bianchi , Wei Yu , Marie Bedora-Faure , et al.
Journal of Immunological Methods, 2017, 451, pp.71-77. ⟨10.1016/j.jim.2017.08.007⟩
Article dans une revue pasteur-03271165v1
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Breakage-Fusion-Bridge Events Trigger Complex Genome Rearrangements and Amplifications in Developmentally Arrested T Cell Lymphomas

Joy Bianchi , Valentine Murigneux , Marie Bedora-Faure , Chloé Lescale , Ludovic Deriano
Cell Reports, 2019, 27 (10), pp.2847-2858.e4. ⟨10.1016/j.celrep.2019.05.014⟩
Article dans une revue pasteur-02757480v1
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Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ

Wei Yu , Chloé Lescale , Loelia Babin , Marie Bedora-Faure , Hélène Lenden-Hasse , et al.
Nature Communications, 2020, 11 (1), pp.5239. ⟨10.1038/s41467-020-19060-w⟩
Article dans une revue pasteur-03262335v1
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Single-cell analysis of thymocyte differentiation: identification of transcription factor interactions and a major stochastic component in $\alpha\beta$-lineage commitment.

Amine Boudil , Lamia Skhiri , Serge Candéias , Valérie Pasqualetto , Agnès Legrand , et al.
PLoS ONE, 2013, 8 (10), pp.e73098. ⟨10.1371/journal.pone.0073098⟩
Article dans une revue hal-01070497v1
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RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair

Chloé Lescale , Vincent Abramowski , Marie Bedora-Faure , Valentine Murigneux , Gabriella Vera , et al.
Nature Communications, 2016, 7, pp.Article number:10529. ⟨10.1038/ncomms10529⟩
Article dans une revue pasteur-01295756v1

The immune system profoundly restricts intratumor genetic heterogeneity

Idan Milo , Marie Bedora-Faure , Zacarias Garcia , Ronan Thibaut , Leïla Perié , et al.
Science Immunology, 2018, 3 (29), pp.eaat1435. ⟨10.1126/sciimmunol.aat1435⟩
Article dans une revue pasteur-01939341v1

Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function

Miguel Galindo-Campos , Marie Bedora-Faure , Jordi Farrés , Chloé Lescale , Lucia Moreno-Lama , et al.
Cell Death and Differentiation, 2019, 26 (12), pp.2667-2681. ⟨10.1038/s41418-019-0326-5⟩
Article dans une revue hal-02369061v1