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Number of documents

49

CV Marc POCARD


Prof. Marc Pocard did his residency in the Paris Hospitals and during the same time studied colorectal cancer biology at the Curie Institut. He worked during 5 years as a surgeon at the Gustave Roussy Institute in Paris during which he also had the opportunity to work on peritoneal metastatic diseases. In 2006 he was nominated Professor in digestive surgery at the Paris Diderot University. He developed a peritoneal metastasis treatment program, in association with the French RENAPE network for rare peritoneal cancers. In 2009 he created a research Unit at the INSERM on Angiogenesis and again in 2019 a research Unit specifically devoted to basic and translational research on peritoneal metastasis. He practices HIPEC and PIPAC in a routine manner and is involved in clinical trials related to peritoneal metastasis. In 2018 he cofounded the International Society for the Study of Pleura and Peritoneum, named ISSPP and was elected as the first president of the ISSPP society.

 

Subjects of interest on research are:

-          Evaluation of new intraperitoneal drugs delivery using nanotechnology, gel as a drug carrier solution or PIPAC and associations for peritoneal metastasis

-          Evaluation of new treatments in Pseudomyxoma animal model

-          Comprehensive study on gastric adenocarcinoma with single ring cells

-          Conception of global evaluation procedure for loco regional treatment in Cancer, including personal and societal aspect


Journal articles49 documents

  • J. Vivier-Chicoteau, J. Lambert, R. Coriat, P. Bonnot, D. Goéré, et al.. Development and internal validation of a diagnostic score for gastric linitis plastica. Gastric Cancer, Springer Verlag (Germany), In press, ⟨10.1007/s10120-020-01051-x⟩. ⟨hal-02555520⟩
  • Thomas Aparicio, Julie Henriques, Sylvain Manfredi, David Tougeron, Olivier Bouche, et al.. Small bowel adenocarcinoma: Results from a nationwide prospective ARCAD‐NADEGE cohort study of 347 patients. International Journal of Cancer, Wiley, 2020, ⟨10.1002/ijc.32860⟩. ⟨hal-02532893⟩
  • J.-J Tuech, A. Gangloff, F. Fiore, P. Michel, C. Brigand, et al.. Strategy for the practice of digestive and oncological surgery during the Covid-19 epidemic.. Journal of Visceral Surgery, Elsevier, In press, ⟨10.1016/j.jviscsurg.2020.03.008⟩. ⟨hal-02552052⟩
  • Jean-Baptiste Delhorme, Jordan Ohayon, Sébastien Gouy, Catherine Genestie, Léopold Gaichies, et al.. Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients. EJSO - European Journal of Surgical Oncology, WB Saunders, 2020, 46 (5), pp.862-867. ⟨10.1016/j.ejso.2019.12.005⟩. ⟨hal-02533020⟩
  • Matti Ullah, Sarah Meziani, Shahid Shah, Rachid Kaci, Cynthia Pimpie, et al.. Differentiation of cancer cells upregulates HLA‑G and PD‑L1. Oncology Reports, Spandidos Publications, 2020, ⟨10.3892/or.2020.7572⟩. ⟨hal-02551167⟩
  • Iman Al Dybiat, Alibi Baitukha, Cynthia Pimpie, Rachid Kaci, Marc Pocard, et al.. Multi-nanolayer drug delivery using radiofrequency plasma technology. BMC Cancer, BioMed Central, 2020, 20 (565), pp.11P. ⟨10.1186/s12885-020-06989-w⟩. ⟨hal-02879735⟩
  • T. Voron, B. Romain, D. Bergeat, J. Veziant, J. Gagnière, et al.. Surgical management of gastric adenocarcinoma. Official expert recommendations delivered under the aegis of the French Association of Surgery (AFC). Journal of Visceral Surgery, Elsevier, 2020, ⟨10.1016/j.jviscsurg.2020.02.006⟩. ⟨hal-02532837⟩
  • Thomas Aparicio, Magali Svrcek, Julie Henriques, Pauline Afchain, Astrid Lièvre, et al.. Panel gene profiling of small bowel adenocarcinoma, results from the NADEGE prospective cohort. International Journal of Cancer, Wiley, 2020, ⟨10.1002/ijc.33392⟩. ⟨hal-03038573⟩
  • Pierre Rompteaux, Johan Gagniere, Jean-Marc Gornet, Romain Coriat, Isabelle Baumgaertner, et al.. Resection of small bowel adenocarcinoma metastases: Results of the ARCAD-NADEGE cohort study. EJSO - European Journal of Surgical Oncology, WB Saunders, 2019, 45 (3), pp.331-335. ⟨10.1016/j.ejso.2018.11.012⟩. ⟨hal-02180462⟩
  • Olivia Sgarbura, Martin Hübner, Mohammad Alyami, Clarisse Eveno, Johan Gagnière, et al.. Oxaliplatin use in pressurized intraperitoneal aerosol chemotherapy (PIPAC) is safe and effective: A multicenter study. EJSO - European Journal of Surgical Oncology, WB Saunders, 2019, 45 (12), pp.2386-2391. ⟨10.1016/j.ejso.2019.05.007⟩. ⟨hal-02432145⟩
  • Alibi Baitukha, Iman Al-Dybiat, Azadeh Valinataj Omran, Jérôme Pulpytel, Marc Pocard, et al.. Optimization of a low pressure plasma process for fabrication of a Drug Delivery System (DDS) for cancer treatment. Materials Science and Engineering: C, Elsevier, 2019, 105, pp.110089. ⟨10.1016/j.msec.2019.110089⟩. ⟨hal-02289769⟩
  • Nayef Alzahrani, Sarah Valle, Oliver Fisher, Paul Sugarbaker, Yutaka Yonemura, et al.. Iterative cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: A multi‐institutional experience. Journal of Surgical Oncology, Wiley-Blackwell, 2019, 119 (3), pp.336-346. ⟨10.1002/jso.25277⟩. ⟨hal-02060121⟩
  • C. Honore, J.B. Delhorme, E. Nassif, M. Faron, G. Ferron, et al.. Can we cure patients with abdominal Desmoplastic Small Round Cell Tumor? Results of a retrospective multicentric study on 100 patients. Surgical Oncology, Elsevier, 2019, 29, pp.107-112. ⟨10.1016/j.suronc.2019.04.002⟩. ⟨hal-02528457⟩
  • Thibault Voron, Caroline Gronnier, Arnaud Pasquer, Jérémie Thereaux, Johan Gagnière, et al.. Adenocarcinoma of the oesophagogastric junction Siewert II: An oesophageal cancer better cured with total gastrectomy. EJSO - European Journal of Surgical Oncology, WB Saunders, 2019, 45 (12), pp.2473-2481. ⟨10.1016/j.ejso.2019.07.022⟩. ⟨hal-02533008⟩
  • Pierre-Emmanuel Bonnot, Guillaume Piessen, Vahan Kepenekian, Evelyne Decullier, Marc Pocard, et al.. Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis. Journal of Clinical Oncology, American Society of Clinical Oncology, 2019, 37 (23), pp.2028-2040. ⟨10.1200/JCO.18.01688⟩. ⟨hal-02420029⟩
  • F. Lécuru, N. Bakrin, J.M. Classe, P.E. Colombo, G. Ferron, et al.. CHIP et cancer de l’ovaire. Gynécologie Obstétrique Fertilité & Sénologie, Elsevier, 2019, 47 (9), pp.617-618. ⟨10.1016/j.gofs.2019.06.007⟩. ⟨hal-02343556⟩
  • Jennifer Pasquier, Marie Gosset, Caroline Geyl, Jessica Hoarau-Véchot, Audrey Chevrot, et al.. CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancer. Molecular Cancer, 2018, 17 (1), pp.47. ⟨10.1186/s12943-018-0787-z⟩. ⟨inserm-01716892⟩
  • M. Bendenoun, A. Samri, V. Avettand-Fenoel, S. Cardinaud, B. Descours, et al.. What Is the most Important for Elite Control: Genetic Background of Patient, Genetic Background of Partner, both or neither? Description of Complete Natural History within a Couple of MSM. EBioMedicine, Elsevier, 2018, 27, pp.51-60. ⟨10.1016/j.ebiom.2017.12.003⟩. ⟨hal-02307154⟩
  • J.-B. Delhorme, F. Severac, G. Averous, O. Glehen, G. Passot, et al.. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei of appendicular and extra-appendicular origin. British Journal of Surgery, Wiley, 2018, 105 (6), pp.668-676. ⟨10.1002/bjs.10716⟩. ⟨hal-02264128⟩
  • I. Amblard, F. Mercier, D.L. Bartlett, S.A. Ahrendt, K.W. Lee, et al.. Cytoreductive surgery and HIPEC improve survival compared to palliative chemotherapy for biliary carcinoma with peritoneal metastasis: A multi-institutional cohort from PSOGI and BIG RENAPE groups. EJSO - European Journal of Surgical Oncology, WB Saunders, 2018, 44 (9), pp.1378-1383. ⟨10.1016/j.ejso.2018.04.023⟩. ⟨hal-02281342⟩
  • Brice Malgras, Etienne Gayat, Olivier Aoun, Réa Lo Dico, Clarisse Eveno, et al.. Impact of combination chemotherapy in peritoneal mesothelioma hyperthermic intraperitoneal chemotherapy (HIPEC): The RENAPE study. Annals of Surgical Oncology, Springer Verlag, 2018, 25 (11), pp.3271-3279. ⟨10.1245/s10434-018-6631-2⟩. ⟨hal-02264137⟩
  • Yang Liu, Yutaka Yonemura, Edward Levine, Olivier Glehen, Diane Goere, et al.. Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases From a Small Bowel Adenocarcinoma: Multi-Institutional Experience. Annals of Surgical Oncology, Springer Verlag, 2018, 25 (5), pp.1184-1192. ⟨10.1245/s10434-018-6369-x⟩. ⟨hal-02290071⟩
  • Christophe Locher, Blaise Batumona, Pauline Afchain, Nicolas Carrère, Emmanuelle Samalin, et al.. Small bowel adenocarcinoma: French intergroup clinical practice guidelines for diagnosis, treatments and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO). Digestive and Liver Disease, WB Saunders, 2018, 50 (1), pp.15 - 19. ⟨10.1016/j.dld.2017.09.123⟩. ⟨hal-01708040⟩
  • M. Bendenoun, A. Samri, V. Avettand-Fènoël, S. Cardinaud, B. Descours, et al.. What Is the most Important for Elite Control: Genetic Background of Patient, Genetic Background of Partner, both or neither? Description of Complete Natural History within a Couple of MSM. EBioMedicine, Elsevier, 2018, 27, pp.51-60. ⟨10.1016/j.ebiom.2017.12.003⟩. ⟨hal-01909034⟩
  • Alibi Baitukha, Farzaneh Arefi-Khonsari, Jérôme Pulpytel, Iman Al-Dybiat, Azadeh Valinataj-Omran, et al.. Low pressure plasma processing of collagen membranes for anti-cancer drug delivery. Journal of Material Sciences & Engineering, OMICS International, 2018, 7 (6), e1000499-(6p.). ⟨10.4172/2169-0022.1000499⟩. ⟨hal-01989881⟩
  • Katy Meunier, Marianne Ferron, Claire Calmel, Jean-François Fléjou, Marc Pocard, et al.. Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer. Genes, Chromosomes and Cancer, Wiley, 2017, ⟨10.1002/gcc.22472⟩. ⟨hal-01548232⟩
  • M Barat, A Fohlen, C Cassinotto, As Jannot, R Dautry, et al.. One-month apparent diffusion coefficient correlates with response to radiofrequency ablation of hepatocellular carcinoma.. Journal of Magnetic Resonance Imaging, Wiley-Blackwell, 2017, 45 (6), pp.1648-1658. ⟨10.1002/jmri.25521⟩. ⟨hal-01576042⟩
  • S. Valmary-Degano, P. Colpart, L. Villeneuve, F. Monnien, L. M'Hamdi, et al.. Immunohistochemical evaluation of two antibodies against PD-L1 and prognostic significance of PD-L1 expression in epithelioid peritoneal malignant mesothelioma: A RENAPE study. European Journal of Surgical Oncology (EJSO), 2017, 43 (10), pp.1915-1923. ⟨10.1016/j.ejso.2017.05.009⟩. ⟨hal-02269932⟩
  • Sheraz Markar, Caroline Gronnier, Alain Duhamel, Hélène Behal, Jérémie Thereaux, et al.. Surgically treated oesophageal cancer developed in a radiated field: Impact on peri-operative and long-term outcomes. European Journal of Cancer, Elsevier, 2017, 75, pp.179-189. ⟨10.1016/j.ejca.2016.12.036⟩. ⟨hal-02050649⟩
  • Eric Rullier, Philippe Rouanet, Jean-Jacques Tuech, Alain Valverde, Bernard Lelong, et al.. Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial. The Lancet, Elsevier, 2017, 390 (10093), pp.469 - 479. ⟨10.1016/S0140-6736(17)31056-5⟩. ⟨hal-01682165⟩
  • Styliani Mantziari, Caroline Gronnier, Arnaud Pasquer, Johan Gagnière, Jérémie Théreaux, et al.. Incidence and Risk Factors Related to Symptomatic Venous Thromboembolic Events After Esophagectomy for Cancer. Annals of Thoracic Surgery, Elsevier, 2016, ⟨10.1016/j.athoracsur.2016.03.093⟩. ⟨hal-01563338⟩
  • L. Villeneuve, A. Thivolet, N. Bakrin, F. Mohamed, S. Isaac, et al.. A new internet tool to report peritoneal malignancy extent. PeRitOneal MalIgnancy Stage Evaluation (PROMISE) application. EJSO - European Journal of Surgical Oncology, WB Saunders, 2016, 42 (6), pp.877-882. ⟨10.1016/j.ejso.2016.03.015⟩. ⟨hal-02297723⟩
  • T. Charrier, G. Passot, Julien Péron, C. Maurice, S. Gocevska, et al.. Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin Increases the Risk of Postoperative Hemorrhagic Complications: Analysis of Predictive Factors. Annals of Surgical Oncology, Springer Verlag, 2016, 23, pp.2315-22. ⟨10.1245/s10434-016-5143-1⟩. ⟨hal-02016407⟩
  • Julie Perinel, Christophe Mariette, Bertrand Dousset, Igor Sielezneff, Alain Gainant, et al.. Early Enteral Versus Total Parenteral Nutrition in Patients Undergoing Pancreaticoduodenectomy: A Randomized Multicenter Controlled Trial (Nutri-DPC). Annals of Surgery, Lippincott, Williams & Wilkins, 2016, 264, pp.731-737. ⟨hal-01466785⟩
  • Sudhir Bhatt, Fatemeh Valamanesh, Jérôme Pulpytel, Rea Lo Dico, Alibi Baitukha, et al.. Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum. Oncotarget, Impact journals, 2016, 7 (36), pp.58121-58132. ⟨hal-01414836⟩
  • Sheraz Markar, Caroline Gronnier, Arnaud Pasquer, Alain Duhamel, Hélène Beal, et al.. Role of neoadjuvant treatment in clinical T2N0M0 oesophageal cancer: results from a retrospective multi-center European study. European Journal of Cancer, Elsevier, 2016, 56, pp.59-68. ⟨10.1016/j.ejca.2015.11.024⟩. ⟨hal-01666517⟩
  • V Kepenekian, D Elias, G Passot, E Mery, D Goere, et al.. Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database Multi-Institutional Retrospective Study *, on behalf of the French Network for Rare Peritoneal Malignancies (RENAPE). European Journal of Cancer, Elsevier, 2016, 65, pp.69-79. ⟨10.1016/j.ejca.2016.06.002⟩. ⟨inserm-01368938⟩
  • Romain Cohen, Magali Svrcek, Chantal Dreyer, Pascale Cervera, Alex Duval, et al.. New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer. Current Oncology Reports, Current Medicine Group, 2016, 18 (3), pp.18. ⟨10.1007/s11912-016-0504-2⟩. ⟨hal-01310853⟩
  • Sergiu Susman, Raphaëlle Barnoud, Frederique Bibeau, Francesco Borini, Marc Pocard, et al.. The Lauren classification highlights the role of epithelial-to-mesenchymal transition in gastric carcinogenesis: an immunohistochemistry study of the STAT3 and adhesion molecules expression. Journal of Gastrointestinal and Liver Diseases, Romanian Societies of Gastroenterology, 2015, 24 (1), pp.77-83. ⟨10.15403/jgld.2014.1121.sus⟩. ⟨hal-02283324⟩
  • A Dohan, S A Faraoun, M Barral, Y Guerrache, M Boudiaf, et al.. Extra-intestinal malignancies in inflammatory bowel diseases: An update with emphasis on MDCT and MR imaging features.. Diagnostic and Interventional Imaging, Elsevier, 2015, [Epub ahead of print]. ⟨hal-01140967⟩
  • G. Ferron, L. Simon, F. Guyon, O. Glehen, D. Goéré, et al.. Professional risks when carrying out cytoreductive surgery for peritoneal malignancy with hyperthermic intraperitoneal chemotherapy (HIPEC): A French multicentric survey. EJSO - European Journal of Surgical Oncology, WB Saunders, 2015, 41 (10), pp.1361-1367. ⟨10.1016/j.ejso.2015.07.012⟩. ⟨hal-02334165⟩
  • Jean-Marc Classe, Olivier Glehen, Evelyne Decullier, Jean Marc Bereder, Simon Msika, et al.. Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for First Relapse of Ovarian Cancer.. Anticancer Research, International Institute of Anticancer Research, 2015, 35 (9), pp.4997-5005. ⟨hal-02326390⟩
  • Hamda Althawadi, Halema Alfarsi, Samaher Besbes, Shahsoltan Mirshahi, Elodie Ducros, et al.. Activated protein C upregulates ovarian cancer cell migration and promotes unclottability of the cancer cell microenvironment. Oncology Reports, Spandidos Publications, 2015, 34 (2), pp.603-609. ⟨10.3892/or.2015.4061⟩. ⟨hal-03123258⟩
  • Pascal Phrakonkham, J.P. Brouland, H.E. Saad, Raymond Berges, C. Pimpie, et al.. Dietary exposure in utero and during lactation to a mixture of genistein and an anti-androgen fungicide in a rat mammary carcinogenesis model. Reproductive Toxicology, Elsevier, 2015, 54, pp.101-109. ⟨10.1016/j.reprotox.2014.05.016⟩. ⟨hal-01207468⟩
  • Diana Cifuentes, Marine Poittevin, Ekrem Dere, Dong Broqueres-You, Philippe Bonnin, et al.. Hypertension Accelerates the Progression of Alzheimer-Like Pathology in a Mouse Model of the Disease. Hypertension, American Heart Association, 2015, 65 (1), pp.218+. ⟨10.1161/HYPERTENSIONAHA.114.04139⟩. ⟨hal-01545785⟩
  • Ingrid Jouvin, Anthony Dohan, P. Gergi, Marc Pocard. Intra-abdominal benign multicystic peritoneal mesothelioma.. Journal of Visceral Surgery, Elsevier, 2014, epub ahead of print. ⟨10.1016/j.jviscsurg.2013.12.014⟩. ⟨inserm-00937139⟩
  • Naoual Bakrin, Jean-Marc Bereder, Evelyne Decullier, Jean-Marc Classe, Simon Msika, et al.. Peritoneal carcinomatosis treated with cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for advanced ovarian carcinoma: A French multicentre retrospective cohort study of 566 patients.. EJSO - European Journal of Surgical Oncology, WB Saunders, 2013, 39 (12), pp.1435-1443. ⟨10.1016/j.ejso.2013.09.030⟩. ⟨hal-00919879⟩
  • Christiane Charriaut-Marlangue, Philippe Bonnin, Abdallah Gharib, Pierre-Louis Leger, Sonia Villapol, et al.. Inhaled nitric oxide reduces brain damage by collateral recruitment in a neonatal stroke model.: Inhaled NO and neonatal stroke. Stroke, American Heart Association, 2012, 43 (11), pp.3078-84. ⟨10.1161/STROKEAHA.112.664243⟩. ⟨inserm-00740744⟩
  • V. Haydont, C. Bourgier, M. Pocard, A. Lusinchi, J. Aigueperse, et al.. Pravastatin inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. Clinical Cancer Research, 2007, 13 (18), pp.5331-5340. ⟨10.1158/1078-0432.CCR-07-0625⟩. ⟨hal-03015590⟩