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Marc Boudvillain

9
Documents
Identifiants chercheurs

Présentation

- **CNRS Research director** and group Leader at CBM - **Deputy director** of CBM since January 2018. Education --------- - **PhD Thesis** in Biochemistry and Molecular Biophysics, University of Orléans (1996). - **Master of Science** (specialty: Biological Chemistry) from the Universities of Orléans, Paris Descartes, and Paris Sud (joint program, 1992). Professional experience ----------------------- - **Tenured Scientist** at CNRS, CBM since October 1999. Biochemistry of RNA and RNA-protein complexes; Regulation of bacterial transcription; RNA helicase mechanisms - **Postdoctoral Research Scientist** at Columbia University and Howard Hugues Medical Institute (New York, USA). Biochemistry of RNA; Structure, function and catalysis by group II intron ribozymes (1996-1999). - **Graduate Research Scientist** at CBM. Nucleic acid Biochemistry; Inorganic chemistry; Engineering of synthetic Pt(II)-based metalloribozymes (1993-1996).

Publications

rachid-rahmouni

The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.

Makhlouf Rabhi , Olivier Espéli , Annie Schwartz , Bastien Cayrol , a Rachid Rahmouni
EMBO Journal, 2011, 30 (14), pp.2805-16. ⟨10.1038/emboj.2011.192⟩
Article dans une revue hal-00720713v1

A stepwise 2 '-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase

Annie Schwartz , Makhlouf Rabhi , Frederique Jacquinot , Emmanuel Margeat , A. Rachid Rahmouni
Nature Structural and Molecular Biology, 2009, 16 (12), pp.1309-1316. ⟨10.1038/nsmb.1711⟩
Article dans une revue hal-00525325v1

Noncanonical Interactions in the Management of RNA Structural Blocks by the Transcription Termination Rho Helicase

Annie Schwartz , Céline Walmacq , A. Rachid Rahmouni , Marc Boudvillain
Biochemistry, 2007, 46 (33), pp.9366 - 9379. ⟨10.1021/bi700493m⟩
Article dans une revue hal-00166551v1
Image document

Transcription termination factor Rho can displace streptavidin from biotinylated RNA

Annie Schwartz , Emmanuel Margeat , A. Rachid Rahmouni , Marc Boudvillain
Journal of Biological Chemistry, 2007, 282 (43), pp.31469-31476. ⟨10.1074/jbc.M706935200⟩
Article dans une revue hal-00176284v1

Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho

C. Walmacq , A.R. Rahmouni , M. Boudvillain
Biochemistry, 2006, 45, pp.5885-5895. ⟨10.1021/bi0600648⟩
Article dans une revue hal-00088941v1

Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions

C. Walmacq , A.R. Rahmouni , M. Boudvillain
Journal of Molecular Biology, 2004, 342 (2), pp.403-420. ⟨10.1016/j.jmb.2004.07.026⟩
Article dans une revue hal-00113090v1

The functional anatomy of an intrinsic transcription terminator

A. Schwartz , A. Rachid Rahmouni , Marc Boudvillain
EMBO Journal, 2003, 22 (13), pp.3385 - 3394. ⟨10.1093/emboj/cdg310⟩
Article dans une revue hal-01880611v1

Limited Topological Alteration of the T7 RNA Polymerase Active Center at Intrinsic Termination Sites †

Marc Boudvillain , Annie Schwartz , A. Rachid Rahmouni
Biochemistry, 2002, 41 (9), pp.3137-3146. ⟨10.1021/bi011358q⟩
Article dans une revue hal-02075291v1