Magalie LECOURTOIS

Documents

Publications

	Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies Laetitia Miguel , Anne Rovelet-Lecrux , Pascal Chambon , Géraldine Joly-Helas , Stéphane Rousseau Stem Cell Research, 2022, 61, pp.102762. ⟨10.1016/j.scr.2022.102762⟩ Article dans une revue hal-03622429v1
	uORF‐introducing variants in the 5′UTR of the NIPBL gene as a cause of Cornelia de Lange syndrome Juliette Coursimault , Anne Rovelet-Lecrux , Kévin Cassinari , Elise Brischoux-Boucher , Pascale Saugier-Veber Human Mutation, 2022, 43 (9), pp.1239-1248. ⟨10.1002/humu.24384⟩ Article dans une revue hal-03822689v1
	Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease Anne Rovelet-Lecrux , Sebastien Feuillette , Laetitia Miguel , Catherine Schramm , Ségolène Pernet Acta Neuropathologica Communications, 2021, 9, ⟨10.1186/s40478-021-01294-4⟩ Article dans une revue hal-03512083v1
	A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila Sébastien Feuillette , Camille Charbonnier , Thierry Frebourg , Dominique Campion , Magalie Lecourtois Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩ Article dans une revue hal-02503970v1
	A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila Sébastien Feuillette , Camille Charbonnier , Thierry Frebourg , Dominique Campion , Magalie Lecourtois Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩ Article dans une revue hal-03080080v1
	Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization Laetitia Miguel , Thierry Frébourg , Dominique Campion , Magalie Lecourtois Journal of Alzheimer's Disease, 2020, pp.1-11. ⟨10.3233/JAD-190906⟩ Article dans une revue hal-02484269v1
	Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons Laetitia Miguel , Anne Rovelet-Lecrux , Maxime Feyeux , Thierry Frebourg , Pierre Nassoy Stem Cell Research, 2019, 40, pp.101541. ⟨10.1016/j.scr.2019.101541⟩ Article dans une revue hal-03038792v1
	Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons Laetitia Miguel , Anne Rovelet-Lecrux , Maxime Feyeux , Thierry Frebourg , Pierre Nassoy Stem Cell Research, 2019, 40, pp.101541. ⟨10.1016/j.scr.2019.101541⟩ Article dans une revue hal-02329946v1
	Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila Marine Pons , Silvia Prieto , Laetitia Miguel , Thierry Frébourg , Dominique Campion Acta Neuropathologica Communications, 2018, 6 (1), ⟨10.1186/s40478-018-0639-5⟩ Article dans une revue hal-02330484v1
	FTLD/ALS-linked TDP-43 mutations do not alter TDP-43’s ability to self-regulate its expression in Drosophila Laetitia Miguel , Tracey Avequin , Marine Pons , Thierry Frébourg , Dominique Campion Brain Research, 2018, 1695, pp.1-9. ⟨10.1016/j.brainres.2018.05.021⟩ Article dans une revue hal-02330526v1
	Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations Sébastien Feuillette , Morgane Delarue , Gaetan Riou , Anne-Lise Gaffuri , Jane Wu Journal of Molecular Neuroscience, 2017, 62 (1), pp.114-122. ⟨10.1007/s12031-017-0908-y⟩ Article dans une revue hal-02330532v1
	Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model Marine Pons , Laetitia Miguel , Camille Miel , Tracey Avequin , François Juge Human Molecular Genetics, 2017, 26 (17), pp.3396-3408. ⟨10.1093/hmg/ddx229⟩ Article dans une revue hal-02330529v1
	Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies Bilal Khalil , Marie-Jeanne Cabirol-Pol , Laetitia Miguel , Alexander J. Whitworth , Magalie Lecourtois Neurobiology of Aging, 2017, 54, pp.71--83. ⟨10.1016/j.neurobiolaging.2017.02.016⟩ Article dans une revue hal-01994093v1
	Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis Irene Salado , Miriam Redondo , Murilo Bello , Concepción Pérez , Nicole Liachko Journal of Medicinal Chemistry, 2014, 57 (6), pp.2755-2772. ⟨10.1021/jm500065f⟩ Article dans une revue hal-02330558v1
	Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models Anita Reinhardt , Sébastien Feuillette , Marlène Cassar , Céline Callens , Hélène Thomassin-Bourrel Frontiers in Genetics, 2012, 3, pp.226. ⟨10.3389/fgene.2012.00226⟩ Article dans une revue hal-01537142v1
	Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes Jack-Christophe Cossec , Jeremie Lavaur , Diego Berman , Isabelle Rivals , Alexander Hoischen Human Molecular Genetics, 2012, 21 (14), pp.3156-3172. ⟨10.1093/hmg/dds142⟩ Article dans une revue hal-02332572v1
	Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila Laetitia Miguel , Tracey Avequin , Morgane Delarue , Sébastien Feuillette , Thierry Frebourg Neurobiology of Aging, 2012, 33 (5), pp.1008.e1-1008.e15. ⟨10.1016/j.neurobiolaging.2011.10.008⟩ Article dans une revue hal-02332201v1
	Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models Anita Reinhardt , Sébastien Feuillette , Marlène Cassar , Céline Callens , Hélène Thomassin Frontiers in Genetics, 2012, 3 (226), 14 p. ⟨10.3389/fgene.2012.00226⟩ Article dans une revue hal-02331191v1
	Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila Yasmina Talmat-Amar , Yoan Arribat , Christelle Redt-Clouet , Sébastien Feuillette , Anne-Laure Bouge Human Molecular Genetics, 2011, 20 (19), pp.3738-3745. ⟨10.1093/hmg/ddr290⟩ Article dans une revue hal-02332575v1
	Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies Laetitia Miguel , Thierry Frebourg , Dominique Campion , Magalie Lecourtois Neurobiology of Disease, 2011, 41 (2), pp.398-406. ⟨10.1016/j.nbd.2010.10.007⟩ Article dans une revue hal-02332578v1
	Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype Magalie Lecourtois , Karine Poirier , Gaëlle Friocourt , Xavier Jaglin , Alice Goldenberg Acta Neuropathologica, 2010, 119 (6), pp.779-789. ⟨10.1007/s00401-010-0684-z⟩ Article dans une revue hal-02332580v1
	Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein Sébastien Feuillette , Laetitia Miguel , Thierry Frebourg , Dominique Campion , Magalie Lecourtois Journal of Neurochemistry, 2010, 113 (4), pp.895-903. ⟨10.1111/j.1471-4159.2010.06663.x⟩ Article dans une revue hal-02332582v1
	Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains Sébastien Feuillette , Vincent Deramecourt , Annie Laquérriere , Charles Duyckaerts , Marie-Bernadette Delisle Brain Research, 2010, 1345, pp.182-189. ⟨10.1016/j.brainres.2010.05.007⟩ Article dans une revue hal-02329958v1
	Partial deletion of the MAPT gene: A novel mechanism of FTDP-17 Anne Rovelet-Lecrux , Magalie Lecourtois , Catherine Thomas-Antérion , Isabelle Le Ber , Alexis Brice Human Mutation, 2009, 30 (4), pp.E591-E602. ⟨10.1002/humu.20979⟩ Article dans une revue hal-02332588v1
	Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila Olivier Blard , Sébastien Feuillette , Jacqueline Bou , Boris Chaumette , Thierry Frebourg Human Molecular Genetics, 2007, 16 (5), pp.555-566. ⟨10.1093/hmg/ddm011⟩ Article dans une revue hal-02332593v1
	Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3β kinase prevents clearance of phosphorylated tau inDrosophila Olivier Blard , Thierry Frebourg , Dominique Campion , Magalie Lecourtois Journal of Neuroscience Research, 2006, 84 (5), pp.1107-1115. ⟨10.1002/jnr.21006⟩ Article dans une revue hal-02332595v1
	Tau is not normally degraded by the proteasome Sébastien Feuillette , Olivier Blard , Magalie Lecourtois , Thierry Frebourg , Dominique Campion Journal of Neuroscience Research, 2005, 80 (3), pp.400-405. ⟨10.1002/jnr.20414⟩ Article dans une revue hal-02332598v1
	Wingless Capture by Frizzled and Frizzled2 in Drosophila Embryos Magalie Lecourtois , Cyrille Alexandre , Laurence Dubois , Jean-Paul Vincent Developmental Biology, 2001, 235 (2), pp.467-475. ⟨10.1006/dbio.2001.0320⟩ Article dans une revue hal-02335777v1

Magalie LECOURTOIS

Publications

Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies

uORF‐introducing variants in the 5′UTR of the NIPBL gene as a cause of Cornelia de Lange syndrome

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization

Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons

Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons

Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

FTLD/ALS-linked TDP-43 mutations do not alter TDP-43’s ability to self-regulate its expression in Drosophila

Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations

Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model

Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies

Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies

Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype

Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

Partial deletion of the MAPT gene: A novel mechanism of FTDP-17

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila

Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3β kinase prevents clearance of phosphorylated tau inDrosophila

Tau is not normally degraded by the proteasome

Wingless Capture by Frizzled and Frizzled2 in Drosophila Embryos