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Plasmodium falciparum: multifaceted resistance to artemisinins

Lucie Paloque , Arba Pramundita Ramadani , Odile Mercereau-Puijalon , Jean-Michel Augereau , Françoise Benoit-Vical
Malaria Journal, 2016, 15 (1), pp.149/1-12. ⟨10.1186/s12936-016-1206-9⟩
Article dans une revue inserm-01322524v1

Multiple phenotypic and genotypic artemisinin sensitivity evaluation of Malian Plasmodium falciparum isolates

Karamoko Niare , Lucie Paloque , Sandie Ménard , Pety Tor , Arba Pramundita Ramadani , et al.
American Journal of Tropical Medicine and Hygiene, 2018, 98 (4), pp.1123-1131. ⟨10.4269/ajtmh.17-0798⟩
Article dans une revue hal-01963527v1

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

Anita Cohen , Peggy Suzanne , Jean-Charles Lancelot , Pierre Verhaeghe , Aurélien Lesnard , et al.
European Journal of Medicinal Chemistry, 2015, 95, pp.16-28. ⟨10.1016/j.ejmech.2015.03.011⟩
Article dans une revue hal-01460555v1
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Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites

Thibaud Reyser , Lucie Paloque , Michel Nguyen , Jean-Michel Augereau , Matthew John Fuchter , et al.
Pharmaceutics, 2023, 15 (10), pp.2440. ⟨10.3390/pharmaceutics15102440⟩
Article dans une revue hal-04269105v1
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Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance

Lucie Paloque , Romain Coppée , Barbara Stokes , Nina Gnädig , Karamoko Niaré , et al.
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), pp.e01320-21. ⟨10.1128/AAC.01320-21⟩
Article dans une revue hal-03561782v1
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Evaluation of antiplasmodial and antileishmanial activities of herbal medicine Pseudelephantopus spiralis (Less.) Cronquist and isolated hirsutinolide-type sesquiterpenoids

Cynthia Girardi , Nicolas Fabre , Lucie Paloque , Arba Pramundita Ramadani , Françoise Benoit-Vical , et al.
Journal of Ethnopharmacology, 2015, 170, pp.167-174. ⟨10.1016/j.jep.2015.05.014⟩
Article dans une revue hal-01925138v1

Discovery of a new antileishmanial hit in 8-nitroquinoline series

Lucie Paloque , Pierre Verhaeghe , Magali Casanova , Caroline Castera-Ducros , Aurélien Dumètre , et al.
European Journal of Medicinal Chemistry, 2012, 54, pp.75-86
Article dans une revue hal-02049707v1

Synthesis, structures, and biological studies of heterobimetallic Au(I)-Ru(II) complexes involving N-heterocyclic carbene-based multidentate ligands

Luca Boselli , Maëlle Carraz , S. Mazeres , Lucie Paloque , German Gonzalez-Aspajo , et al.
Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩
Article dans une revue hal-01925137v1
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Hybrid Peptide-Alkoxyamine Drugs: A Strategy for the Development of a New Family of Antiplasmodial Drugs

Ange W Embo-Ibouanga , Michel Nguyen , Lucie Paloque , Mathilde Coustets , Jean-Patrick Joly , et al.
Molecules, 2024, 29, pp.1397. ⟨10.3390/molecules29061397⟩
Article dans une revue hal-04515160v1

Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism

Lucie Paloque , Benoit Witkowski , Joël Lelièvre , Manel Ouji , Tanila Ben Haddou , et al.
Journal of Antimicrobial Chemotherapy, 2018, 73 (2), pp.395-403. ⟨10.1093/jac/dkx412⟩
Article dans une revue hal-01963522v1

Novel 8-nitroquinolin-2(1 H )-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

Julien Pedron , Clotilde Boudot , Sébastien Hutter , Sandra Bourgeade-Delmas , Jean-Luc Stigliani , et al.
European Journal of Medicinal Chemistry, 2018, 155, pp.135 - 152. ⟨10.1016/j.ejmech.2018.06.001⟩
Article dans une revue hal-01888465v1
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Synthesis, characterization, and antileishmanial activities of gold(I) complexes involving quinoline functionalized N-heterocyclic carbenes

Lucie Paloque , Catherine Hemmert , Alexis Valentin , Heinz Gornitzka
European Journal of Medicinal Chemistry, 2015, 94, pp.22-29. ⟨10.1016/j.ejmech.2015.02.046⟩
Article dans une revue hal-01925132v1
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Antiprotozoal properties of Indonesian medicinal plant extracts

Arba Pramundita Ramadani , Lucie Paloque , Hugo Belda , Hady Anshory Tamhid , Jumina Masriani , et al.
Journal of Herbal Medicine, 2018, 11, pp.46-52. ⟨10.1016/j.hermed.2017.06.004⟩
Article dans une revue hal-01963518v1
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Zebiriosides A-L, oleanane saponins from the roots of Dendrobangia boliviana

Ilhem Zebiri , Mohamed Haddad , Laurent Duca , Dominique Harakat , Billy Cabanillas , et al.
Phytochemistry, 2016, 130, pp.262-272. ⟨10.1016/j.phytochem.2016.06.006⟩
Article dans une revue hal-01937592v1
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A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites

Henriette Bosson-Vanga , Nicolas Primas , Jean-François Franetich , Catherine Lavazec , Lina Gomez , et al.
Microbiology Spectrum, 2021, 9 (2), pp.e00274-21. ⟨10.1128/Spectrum.00274-21⟩
Article dans une revue hal-03363796v1
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Résistance de l'agent du paludisme, Plasmodium falciparum aux combinaisons thérapeutiques à base d'artémisinine (ACTs) : Craintes d'une chimiorésistance généralisée

Françoise Benoit-Vical , Lucie Paloque , Jean-Michel Augereau
Bulletin de l'Académie Nationale de Médecine, 2016, 200 (3), pp.477-490
Article dans une revue hal-03232081v1

Targeting the human parasite Leishmania donovani: Discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series

Caroline Castera-Ducros , Lucie Paloque , Pierre Verhaeghe , Magali Casanova , Christophe Cantelli , et al.
Bioorganic and Medicinal Chemistry, 2013, 21 (22), pp.7155--7164. ⟨10.1016/j.bmc.2013.09.002⟩
Article dans une revue istex hal-01460446v1

A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania

Lucie Paloque , Nicolas Nvidal@mnhn.Fr Vidal , Magali Casanova , Aurélien Dumètre , Pierre Verhaeghe , et al.
Journal of Microbiological Methods, 2013, 95 (3), pp.320--323. ⟨10.1016/j.mimet.2013.09.006⟩
Article dans une revue hal-01460476v1
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Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination

Manel Ouji , Jean-Michel Augereau , Lucie Paloque , Françoise Benoit-Vical
Parasite, 2018, 25, pp.24. ⟨10.1051/parasite/2018021⟩
Article dans une revue hal-01963526v1
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2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum

Dyhia Amrane , Christophe-Sébastien Arnold , Sébastien Hutter , Julen Sanz-Serrano , Miguel Collia , et al.
Pharmaceuticals, 2021, 14 (8), pp.724. ⟨10.3390/ph14080724⟩
Article dans une revue hal-03323862v1

Synthesis and evaluation of monoamidoxime derivatives: Toward new antileishmanial compounds

Lucie Paloque , Ahlem Bouhlel , Christophe Curti , Aurélien Dumètre , Pierre Verhaeghe , et al.
European Journal of Medicinal Chemistry, 2011, 46 (7), pp.2984--2991. ⟨10.1016/j.ejmech.2011.04.026⟩
Article dans une revue istex hal-01460338v1
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Identification of compounds active against quiescent artemisinin-resistant Plasmodium falciparum parasites via the quiescent-stage survival assay (QSA)

Thibaud Reyser , Lucie Paloque , Manel Ouji , Michel Nguyen , Sandie Ménard , et al.
Journal of Antimicrobial Chemotherapy, 2020, 75 (10), pp.2826-2834. ⟨10.1093/jac/dkaa250⟩
Article dans une revue hal-02948398v1
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Polyunsaturated fatty acid metabolites: biosynthesis in Leishmania and role in parasite/host interaction

Lucie Paloque , Teresa Pérez-Berezo , Anne Abot , Jessica Dalloux-Chioccioli , Sandra Bourgeade-Delmas , et al.
Journal of Lipid Research, 2019, 60 (3), pp.636-647. ⟨10.1194/jlr.M091736⟩
Article dans une revue hal-02140502v1

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series

Charline Kieffer , Anita Cohen , Pierre Verhaeghe , Lucie Paloque , Sébastien Hutter , et al.
Bioorganic and Medicinal Chemistry, 2015, 23 (10), pp.2377-2386. ⟨10.1016/j.bmc.2015.03.064⟩
Article dans une revue hal-01460646v1

Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs): Fears of widespread drug resistance

Françoise Benoit-Vical , Lucie Paloque , Jean-Michel Augereau
Bulletin de l'Académie Nationale de Médecine, 2016, 200 (3), pp.477-489
Article dans une revue hal-01937598v1
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Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1 H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions

Julien Pedron , Clotilde Boudot , Sandra Bourgeade-Delmas , Alix Sournia-Saquet , Lucie Paloque , et al.
ChemMedChem, 2018, 13 (20), pp.2217-2228. ⟨10.1002/cmdc.201800456⟩
Article dans une revue hal-01888530v1
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Epigenetic regulation as a therapeutic target in the malaria parasite Plasmodium falciparum

Thibaud Reyser , Lucie Paloque , Jean-Michel Augereau , Luisa Di Stefano , Françoise Benoit-Vical
Malaria Journal, 2024, 23 (1), pp.44. ⟨10.1186/s12936-024-04855-9⟩
Article dans une revue hal-04502290v1
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Antiplasmodial activities of gold(I) complexes involving functionalized N-heterocyclic carbenes

Catherine Hemmert , Arba Pramundita Ramadani , Luca Boselli , Alvaro Fernandez Alvarez , Lucie Paloque , et al.
Bioorganic and Medicinal Chemistry, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
Article dans une revue hal-01937596v1
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A new phthalide derivative from Peperomia nivalis

Pedro Vásquez-Ocmín , Mohamed Haddad , Alice Gadea , Valérie Jullian , Denis Castillo , et al.
Natural Product Research, 2017, 31 (2), pp.138-142. ⟨10.1080/14786419.2016.1219857⟩
Article dans une revue ird-01381569v1

Synthèse et évaluations biologiques de nouvelles 8-nitroquinoléin-2(1H)-ones antiparisitaires.

Julien Pedron , Clotilde Boudot , Sebastien Hutter , Sandra Bourgeade-Delmas , Lucie Paloque , et al.
8èmes Journées du Consortium anti-Parasitaires et anti-Fongique (CaPF), Mar 2018, Lyon, France
Communication dans un congrès hal-01939612v1