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Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

Guillaume Tetreau , Anne-Sophie Banneville , Elena Andreeva , Aaron Brewster , Mark Hunter , et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-14894-w⟩
Article dans une revue hal-02506591v1
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Phosphomimetic mutations modulate the ability of HIV-1 Rev to bind human Importin β in vitro

Nadia Ben Fadhel , Luca Signor , Carlo Petosa , Marjolaine Noirclerc-Savoye
Article dans une revue hal-02270755v1

Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo

Dan Yu , Zhiqiang Dong , William Clay Gustafson , Rubén Ruiz-González , Luca Signor , et al.
Protein Science, 2016, 25 (2), pp.308-315. ⟨10.1002/pro.2843⟩
Article dans une revue hal-01234552v1

Characterizing Intact Macromolecular Complexes Using Native Mass Spectrometry.

Elisabetta Boeri Erba , Luca Signor , Mizar Francesca Oliva , Fabienne Hans , Carlo Petosa
Methods in Molecular Biology, 2018, 1764, pp.133-151. ⟨10.1007/978-1-4939-7759-8_9⟩
Article dans une revue hal-01807803v1

Quaternary Structure of Fur Proteins, a New Subfamily of Tetrameric Proteins

Julien Pérard , Jacques Covès , Mathieu Castellan , Serge Solard , Myriam Savard , et al.
Biochemistry, 2016, 55 (10), pp.1503-1515. ⟨10.1021/acs.biochem.5b01061⟩
Article dans une revue hal-01291325v1
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Divalent cations influence the dimerization mode of murine S100A9 protein by modulating its disulfide bond pattern

Luca Signor , Theo Paris , Caroline Mas , Adrien Picard , Georges Lutfalla , et al.
Journal of Structural Biology, 2021, 213 (1), pp.107689. ⟨10.1016/j.jsb.2020.107689⟩
Article dans une revue hal-03120644v1

Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly

Simona Antonova , Matthias Haffke , Eleonora Corradini , Mykolas Mikuciunas , Teck Low , et al.
Nature Structural and Molecular Biology, 2018, 25 (12), pp.1119-1127
Article dans une revue hal-01950091v1

Single glutamate to aspartate mutation makes ferric uptake regulator (Fur) as sensitive to H2O2 as peroxide resistance regulator (PerR).

Aubérie Parent , Christelle Caux-Thang , Luca Signor , Martin Clémancey , Ramakrishnan Sethu , et al.
Angewandte Chemie International Edition, 2013, 52 (39), pp.10339-43. ⟨10.1002/anie.201304021⟩
Article dans une revue istex hal-01069668v1
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A crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments.

Ricardo Pires , Bettina Hartlieb , Luca Signor , Guy Schoehn , Suman Lata , et al.
Structure, 2009, 17 (6), pp.843-56. ⟨10.1016/j.str.2009.04.007⟩
Article dans une revue inserm-00405383v1

In vitro reconstitution of peptidoglycan assembly from the Gram-positive pathogen Streptococcus pneumoniae.

André Zapun , Jules Philippe , Katherine A Abrahams , Luca Signor , David I Roper , et al.
ACS Chemical Biology, 2013, 8 (12), pp.2688-96
Article dans une revue hal-01322359v1

Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.

Erika Pellegrini , Luca Signor , Saurabh Singh , Elisabetta Boeri Erba , Stephen Cusack
PLoS ONE, 2017, 12 (5), pp.e0177161. ⟨10.1371/journal.pone.0177161⟩
Article dans une revue hal-01538761v1

Headless C1q: a new molecular tool to decipher its collagen‐like functions

Guillaume Fouët , Isabelle Bally , Luca Signor , Katharina Häussermann , Nicole M. Thielens , et al.
FEBS Journal, 2020, ⟨10.1111/febs.15543⟩
Article dans une revue hal-02954759v1
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Tailing miniSOG: structural bases of the complex photophysics of a flavin-binding singlet oxygen photosensitizing protein

Joaquim Torra , Céline Lafaye , Luca Signor , Sylvain Aumonier , Cristina Flors , et al.
Scientific Reports, 2019, 9 (1), pp.2428-1-2428-10. ⟨10.1038/s41598-019-38955-3⟩
Article dans une revue hal-02306813v1
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Exploring the structure and dynamics of macromolecular complexes by native mass spectrometry

Elisabetta Boeri Erba , Luca Signor , Carlo Petosa
Journal of Proteomics, 2020, 222, pp.103799. ⟨10.1016/j.jprot.2020.103799⟩
Article dans une revue hal-02864550v1

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa

Charlotte Lombardi , James Tolchard , Stéphanie Bouillot , Luca Signor , Caroline Gébus , et al.
Frontiers in Microbiology, 2019, 10 (573), ⟨10.3389/fmicb.2019.00573⟩
Article dans une revue hal-02086007v1
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A solvent-exposed cysteine forms a peculiar Ni(II)-binding site in the metallochaperone CooT from Rhodospirillum rubrum.

Marila Alfano , Giulia Veronesi , Francesco Musiani , Barbara Zambelli , Luca Signor , et al.
Chemistry - A European Journal, 2019, 25 (67), pp.15351-15360. ⟨10.1002/chem.201903492⟩
Article dans une revue hal-02289379v1
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Assembly of The Mitochondrial Complex I Assembly Complex Suggests a Regulatory Role for Deflavination

Gabriele Giachin , Matthew Jessop , Romain Bouverot , Samira Acajjaoui , Melissa Saïdi , et al.
Angewandte Chemie International Edition, 2020, ⟨10.1002/anie.202011548⟩
Article dans une revue hal-03119718v1

Reconstitution of membrane protein complexes involved in pneumococcal septal cell wall assembly.

Marjolaine Noirclerc-Savoye , Violaine Lantez , Luca Signor , Jules Philippe , Thierry Vernet , et al.
PLoS ONE, 2013, 8 (9), pp.e75522
Article dans une revue hal-01322355v1

Combining a NHS ester and glutaraldehyde improves crosslinking prior to MALDI MS analysis of intact protein complexes.

Elisabetta Boeri Erba , Pierre Andre Klein , Luca Signor
Biological Mass Spectrometry, 2015, 50 (10), pp.1114-9
Article dans une revue hal-01234549v1
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Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor

Silke Wollers , Gunhild Layer , Ricardo Garcia-Serres , Luca Signor , Martin Clemancey , et al.
Journal of Biological Chemistry, 2010, 285 (30), pp.23331-23341. ⟨10.1074/jbc.M110.127449⟩
Article dans une revue hal-01053728v1

Reaction of PerR with Molecular Oxygen May Assist H2O2 Sensing in Anaerobes.

Ramakrishan Sethu , Eric Gouré , Luca Signor , Christelle Caux-Thang , Martin Clémancey , et al.
ACS Chemical Biology, 2016, 11 (5), pp.1438-1444. ⟨10.1021/acschembio.5b01054⟩
Article dans une revue hal-01345260v1
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RIP2 filament formation is required for NOD2 dependent NF-κB signalling

Erika Pellegrini , Ambroise Desfosses , Arndt Wallmann , Wiebke Manuela Schulze , Kristina Rehbein , et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06451-3⟩
Article dans une revue hal-01889011v1

Investigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: Plasmepsin 2 but not plasmepsin 4 is active under quenching conditions

Julien Marcoux , Eric Thierry , Corinne Vivès , Luca Signor , Franck Fieschi , et al.
Journal of The American Society for Mass Spectrometry, 2010, 21 (1), pp.76-79. ⟨10.1016/j.jasms.2009.09.005⟩
Article dans une revue hal-02335576v1

Towards a molecular understanding of the water purification properties of Moringa seed proteins

M. Moulin , E. Mossou , Luca Signor , S. Kieffer-Jaquinod , H. M. Kwaambwa , et al.
Journal of Colloid and Interface Science, 2019, 554, pp.296-304. ⟨10.1016/j.jcis.2019.06.071⟩
Article dans une revue cea-02316810v1

Matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometric analysis of intact proteins larger than 100 kDa.

Luca Signor , Elisabetta Boeri Erba
Journal of visualized experiments : JoVE, 2013, 79
Article dans une revue hal-01322394v1