Skip to Main content
Number of documents

82

CV Luc Maroteaux

 

CURRICULUM VITAE

 

 

 

n  Nom, prénom :                   MAROTEAUX, Luc

 

Date et lieu de naissance:    14 Septembre 1955, Versailles, France

 

Grade :                                   Directeur de Recherche 1° Classe CNRS

 

Adresse Professionnelle :    INSERM U839-U1270

 

                                               Institut du Fer à Moulin

 

                                               Rue du Fer à Moulin

 

                                               75005 PARIS

 

Email :                                   luc.maroteaux@upmc.fr

 

Tel :                                        33 (0)1.45.87.61.23

 

Fax :                                       33 (0)1.45.87.61.32

 

 

 

 

 

DEROULEMENT DE CARRIERE

 

1976-1980 : Ecole Normale Supérieure St Cloud

 

1979 : DEA de Biologie Moléculaire - Univ.L. Pasteur Strasbourg. Biologie Moléculaire (P. Chambon) Séquence et identification de la première "TATA BOX" eucaryote.

 

1981-1983 : stage pré doctoral (laboratoire du Pr. M. Revel) Institut Weissman - Israël Clonage des interférons humains alpha et beta.

 

1984 : Thèse d'état en Biologie Moléculaire (Pr P. Chambon) - Université L. Pasteur - Strasbourg: Etude de la régulation de la transcription de l'interféron beta1 humain.

 

1984-1985 : Chargé de recherches 2° classe CNRS - Banyuls sur Mer.

 

1985-1987 : Chargé de recherches 2° classe CNRS - Banyuls sur Mer. Clonage des gènes ribosomiques de Dinoflagellés- Evolution moléculaire.

 

1987-1989 : Post-doctorat- en neurobiologie moléculaire (laboratoire R. Scheller) Université de Stanford, USA. Clonage et caractérisation des synucléines.

 

1989-1993 : Chargé de recherches 1° classe CNRS - Laboratoire du Pr P. Chambon - Strasbourg. Clonage de nouveaux GPCRs.

 

1993 : Directeur de recherches 2° classe CNRS - direction d'un groupe de recherche sur le rôle morphogène de la sérotonine à l’IGBMC Strasbourg.

 

2001 : Directeur de recherches 1° classe - CNRS à l’IGBMC Strasbourg.

 

2004: Mutation à Paris, Création de l’U616 Inserm Sérotonine et développement

 

2007: Création de l’U839 Inserm-Institut du Fer à Moulin Responsable de l'équipe 5 " Signalisation de la sérotonine dans la plasticité et la pathologie"

 

2019: Renouvellement-création de l’U1270 Inserm-Institut du Fer à Moulin Responsable de l'équipe 5 " Sérotonine, microglie, plasticité et la pathologie"

 

 

 

Journal articles77 documents

  • J Caleb Snider, Lance A Riley, Noah T Mallory, Matthew R Bersi, Prachi Umbarkar, et al.. Targeting 5-HT 2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling after Myocardial Infarction. Circulation, American Heart Association, 2021, ⟨10.1161/CIRCULATIONAHA.120.051517⟩. ⟨hal-03121681⟩
  • Amina Benhadda, Emily Quentin, Imane Moutkine, Benjamin Chanrion, Marion Russeau, et al.. Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses. ACS Chemical Neuroscience, American Chemical Society (ACS), 2021, ⟨10.1021/acschemneuro.0c00638⟩. ⟨hal-03176117⟩
  • Catherine Béchade, Ivana d'Andrea, Fanny Etienne, Franck Verdonk, Imane Moutkine, et al.. The serotonin 2B receptor is required in neonatal microglia to limit neuroinflammation and sickness behavior in adulthood. Glia, Wiley, 2020, ⟨10.1002/glia.23918⟩. ⟨hal-02978295⟩
  • Jérôme Lacoste, Sandrine Lamy, Nicolas Ramoz, Nicolas Ballon, Louis Jehel, et al.. A positive association between a polymorphism in the HTR2B gene and cocaine-crack in a French Caribbean population. World Journal of Biological Psychiatry, Taylor & Francis, 2020, 21 (10), pp.784-789. ⟨10.1080/15622975.2018.1563721⟩. ⟨hal-01971860⟩
  • Nicholas M Barnes, Gerard P Ahern, Carine Becamel, Joël Bockaert, Michael Camilleri, et al.. International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function. Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, 2020, 73 (1), pp.310-520. ⟨10.1124/pr.118.015552⟩. ⟨hal-03099832⟩
  • Concha Nieto, Ignacio Rayo, Mateo de Las Casas-Engel, Elena Izquierdo, Bárbara Alonso, et al.. Serotonin (5-HT) Shapes the Macrophage Gene Profile through the 5-HT2B –Dependent Activation of the Aryl Hydrocarbon Receptor. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, pp.ji1901531. ⟨10.4049/jimmunol.1901531⟩. ⟨hal-02544960⟩
  • David Sibon, Tereza Coman, Julien Rossignol, Mathilde Lamarque, Olivier Kosmider, et al.. Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin. Cell Reports, Elsevier Inc, 2019, 26 (12), pp.3246-3256.e4. ⟨10.1016/j.celrep.2019.02.071⟩. ⟨hal-02086600⟩
  • Arnauld Belmer, Luc Maroteaux. Regulation of raphe serotonin neurons by serotonin 1A and 2B receptors. Neuropsychopharmacology, Nature Publishing Group, 2019, 44 (1), pp.218-219. ⟨10.1038/s41386-018-0214-6⟩. ⟨hal-01890660⟩
  • Kristina Valentinova, Anna Tchenio, Massimo Trusel, Joseph Clerke, Arnaud Lalive, et al.. Morphine withdrawal recruits lateral habenula cytokine signaling to reduce synaptic excitation and sociability. Nature Neuroscience, Nature Publishing Group, 2019, 22 (7), pp.1053-1056. ⟨10.1038/s41593-019-0421-4⟩. ⟨hal-02348080⟩
  • Fanny Etienne, Vincenzo Mastrolia, Luc Maroteaux, Jean‐antoine Girault, Nicolas Gervasi, et al.. Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices. Journal of visualized experiments : JoVE, JoVE, 2019, ⟨10.3791/58788⟩. ⟨hal-02348070⟩
  • Imane Moutkine, Emily Lauren Collins, Catherine Béchade, Luc Maroteaux. Evolutionary considerations on 5-HT2 receptors. Pharmacological Research, Elsevier, 2019, 140, pp.14-20. ⟨10.1016/j.phrs.2018.09.014⟩. ⟨hal-01890665⟩
  • Luc Maroteaux, Catherine Béchade, Anne Roumier. Dimers of serotonin receptors: impact on ligand affinity and signaling. Biochimie, Elsevier, 2019, 161, pp.23-33. ⟨10.1016/j.biochi.2019.01.009⟩. ⟨hal-01996206⟩
  • Arnauld Belmer, Emily Quentin, Silvina L. Diaz, Bruno Guiard, Sebastian P Fernandez, et al.. Positive regulation of raphe serotonin neurons by serotonin 2B receptors. Neuropsychopharmacology, Nature Publishing Group, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩. ⟨hal-01703916⟩
  • Janitza L Montalvo-Ortiz, Hang Zhou, Ivana D 'Andrea, Luc Maroteaux, Adriana Lori, et al.. Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response. Molecular Psychiatry, Nature Publishing Group, 2018, 23 (12), pp.2277-2286. ⟨10.1038/s41380-018-0077-6⟩. ⟨hal-01825924⟩
  • Luc Maroteaux, Fusun Kilic. Frontiers of Serotonin Beyond the Brain. Pharmacological Research, Elsevier, 2018, 140, pp.1-6. ⟨10.1016/j.phrs.2018.10.022⟩. ⟨hal-01915456⟩
  • Sarah Nicolas, Delphine Debayle, Catherine Béchade, Luc Maroteaux, Anne-Sophie Gay, et al.. Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression. Translational Psychiatry, Nature Pub. Group, 2018, 8, pp.159. ⟨10.1038/s41398-018-0210-y⟩. ⟨hal-01868962⟩
  • Sarah Nicolas, Delphine Debayle, Catherine Béchade, Luc Maroteaux, Anne-Sophie Gay, et al.. Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression. Translational Psychiatry, Nature Pub. Group, 2018, 8 (1), pp.159. ⟨10.1038/s41398-018-0210-y⟩. ⟨inserm-02438258⟩
  • Emily Quentin, Arnauld Belmer, Luc Maroteaux. Somato-Dendritic Regulation of Raphe Serotonin Neurons; A Key to Antidepressant Action. Frontiers in Neuroscience, Frontiers, 2018, 12, pp.982. ⟨10.3389/fnins.2018.00982⟩. ⟨hal-01980026⟩
  • Emily Quentin, Arnauld Belmer, Luc Maroteaux. SOMATO-DENDRITIC REGULATION OF RAPHE SEROTONIN NEURONS; A KEY TO ANTIDEPRESSANT ACTION. Serotonin volume transmission. Frontiers in Neuroscience, Frontiers, 2018, 12, pp.982. ⟨10.3389/fnins.2018.00982⟩. ⟨hal-01976030⟩
  • Estelle Ayme-Dietrich, Gaëlle Aubertin-Kirch, Luc Maroteaux, Laurent Monassier. Cardiovascular remodeling and the peripheral serotonergic system. Archives of cardiovascular diseases, Elsevier/French Society of Cardiology, 2017, 110 (1), pp.51 - 59. ⟨10.1016/j.acvd.2016.08.002⟩. ⟨hal-01593856⟩
  • Estelle Ayme-Dietrich, Roland Lawson, Francine Côté, Claudia de Tapia, Sylvia da Silva, et al.. Serotonergic 5-HT 2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors. British Journal of Pharmacology, Wiley, 2017, ⟨10.1111/bph.13981⟩. ⟨hal-01593837⟩
  • Coedy Hadden, Tariq Fahmi, Anthonya Cooper, Alena V. Savenka, Vladimir V. Lupashin, et al.. Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway. Journal of Cellular Physiology, Wiley, 2017, 232 (12), pp.3520 - 3529. ⟨10.1002/jcp.25812⟩. ⟨hal-01593857⟩
  • Alexandra Jean, Laetitia Laurent, Sabira Delaunay, Stéphane Doly, Nicole Dusticier, et al.. Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress. Cell Reports, Elsevier Inc, 2017, 21 (4), pp.901-909. ⟨10.1016/j.celrep.2017.10.003⟩. ⟨hal-01667516⟩
  • Imane Moutkine, Emily Quentin, Bruno P. Guiard, Luc Maroteaux, Stephane Doly. Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT 2C protomers. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (15), pp.6352-6368. ⟨10.1074/jbc.M117.779041⟩. ⟨hal-01593841⟩
  • Stephane Doly, Emily Quentin, Raphaël Eddine, Stefania Tolu, Sebastian P Fernandez, et al.. Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses. Journal of Neuroscience, Society for Neuroscience, 2017, 37 (43), pp.10372-10388. ⟨10.1523/JNEUROSCI.1354-17.2017⟩. ⟨hal-01593826⟩
  • Estelle Ayme-Dietrich, Sophie M. Banas, Laurent Monassier, Luc Maroteaux. Hypertension artérielle pulmonaire, moelle osseuse, précurseurs endothéliaux et sérotonine. Biologie Aujourd'hui, EDP sciences, 2016, 210 (2), pp.79-88. ⟨10.1051/jbio/2016012⟩. ⟨hal-01593852⟩
  • Yicong Li, Anthonya Cooper, Imelda N Odibo, Asli Ahmed, Pamela Murphy, et al.. Discrepancy in insulin regulation between GDM-platelets and -placenta. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, ⟨10.1074/jbc.M116.713693⟩. ⟨hal-01280557⟩
  • Hajer El Oussini, Hanna Bayer, Jelena Scekic-Zahirovic, Pauline Vercruysse, Jérôme Sinniger, et al.. Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.. Acta Neuropathologica, Springer Verlag, 2016, 131 (3), pp.465-480. ⟨10.1007/s00401-016-1534-4⟩. ⟨hal-01253857⟩
  • Luc Maroteaux, Estelle Ayme-Dietrich, Gaëlle Aubertin-Kirch, Sophie Banas, Emily Quentin, et al.. New therapeutic opportunities for 5-HT2 receptor ligands. Pharmacology and Therapeutics, Elsevier, 2016, 170, pp.14 - 36. ⟨10.1016/j.pharmthera.2016.10.008⟩. ⟨hal-01387994⟩
  • Pothitos M Pitychoutis, Arnauld Belmer, Imane Moutkine, Joëlle Adrien, Luc Maroteaux. Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology., 2015, 40 (12), pp.2764-73. ⟨10.1038/npp.2015.126⟩. ⟨inserm-01149629⟩
  • Silvina Laura Diaz, Nicolas Narboux-Nême, Katia Boutourlinsky, Stéphane Doly, Luc Maroteaux. Mice lacking the serotonin 5-HT2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants.. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, 26 (2), pp.265-279. ⟨10.1016/j.euroneuro.2015.12.012⟩. ⟨hal-01253863⟩
  • M Kolodziejczak, C Béchade, N Gervasi, T Irinopoulou, Sm Banas, et al.. Serotonin Modulates Developmental Microglia via 5-HT2B Receptors: Potential Implication during Synaptic Refinement of Retinogeniculate Projections.. ACS Chemical Neuroscience, American Chemical Society (ACS), 2015, 6 (7), pp.1219-1230. ⟨10.1021/cn5003489⟩. ⟨hal-01224546⟩
  • Sophie M. Banas, Silvina L. Diaz, Stéphane Doly, Arnauld Belmer, Luc Maroteaux. Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift. Frontiers in Behavioral Neuroscience, Frontiers, 2015, 9, pp.207. ⟨10.3389/fnbeh.2015.00207⟩. ⟨hal-01225050v2⟩
  • Estelle Ayme-Dietrich, Halim Marzak, Roland Lawson, Walid Mokni, Olivia Wendling, et al.. Contribution of serotonin to cardiac remodeling associated with hypertensive diastolic ventricular dysfunction in rats. Journal of Hypertension, Lippincott, Williams & Wilkins, 2015, 33 (11), pp.2310 - 2321. ⟨10.1097/HJH.0000000000000695⟩. ⟨hal-01593863⟩
  • Arnauld Belmer, Stephane Doly, Vincent Setola, Sophie M. Banas, Imane Moutkine, et al.. Role of the N-terminal region in G protein-coupled receptor functions: negative modulation revealed by 5-HT2B receptor polymorphisms.. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2014, 85 (1), pp.127-38. ⟨10.1124/mol.113.089086⟩. ⟨inserm-00996746⟩
  • Yicong Li, Coedy Hadden, Preeti Singh, Charles P Mercado, Pamela Murphy, et al.. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake.. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (52), pp.E5697-705. ⟨10.1073/pnas.1416675112⟩. ⟨hal-01225032⟩
  • Charles P. Mercado, Maritza V. Quintero, Yicong Li, Preeti Singh, Alicia K. Byrd, et al.. A serotonin-induced N-glycan switch regulates platelet aggregation.. Scientific Reports, Nature Publishing Group, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩. ⟨inserm-00996761⟩
  • Silvina L. Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B. Kleine Borgmann, et al.. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin.. European Journal of Neuroscience, Wiley, 2013, 38 (5), pp.2650-8. ⟨10.1111/ejn.12297⟩. ⟨inserm-00996749⟩
  • Luc Maroteaux. Overexpression of 5-hydroxytryptamine 2B receptor gene in pulmonary hypertension: still a long way to understand its transcriptional regulation.. Hypertension, American Heart Association, 2013, 61 (4), pp.e28-9. ⟨10.1161/HYPERTENSIONAHA.111.00702⟩. ⟨inserm-00996750⟩
  • Silviana Laura Diaz, Stéphane Doly, Nicolas Narboux-Nême, Sébasatien Fernández, Pierre Mazot, et al.. 5-HT(2B) receptors are required for serotonin-selective antidepressant actions.. Molecular Psychiatry, Nature Publishing Group, 2012, 17 (2), pp.154-63. ⟨10.1038/mp.2011.159⟩. ⟨inserm-00652573⟩
  • Jean-Marie Launay, Philippe Hervé, Jacques Callebert, Ziad Mallat, Corinne Collet, et al.. Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension.. Blood, American Society of Hematology, 2012, 119 (7), pp.1772-80. ⟨10.1182/blood-2011-06-358374⟩. ⟨inserm-00996752⟩
  • Yasmine Chabbi-Achengli, Jean-Marie Launay, Luc Maroteaux, Marie Christine de Vernejoul, Corinne Collet. Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts.. PLoS ONE, Public Library of Science, 2012, 8 (9), pp.e75783. ⟨10.1371/journal.pone.0075783⟩. ⟨hal-01225060⟩
  • Nataliya Urtikova, Nadège Berson, Juliette van Steenwinckel, Stéphane Doly, Jérémy Truchetto, et al.. Anti-nociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.. PAIN, Elsevier, 2012, 153 (6), pp.1320-31. ⟨10.1016/j.pain.2012.03.024⟩. ⟨hal-01225065⟩
  • Sophie M. Banas, Stéphane Doly, Katia Boutourlinsky, Silvina L. Diaz, Arnauld Belmer, et al.. Deconstructing Antiobesity Compound Action: Requirement of Serotonin 5-HT(2B) Receptors for Dexfenfluramine Anorectic Effects.: Anorectic compounds and 5-HTreceptors. Neuropsychopharmacology, Nature Publishing Group, 2011, 36 (2), pp.423-33. ⟨10.1038/npp.2010.173⟩. ⟨hal-00583533v2⟩
  • Mohammad R. Ebrahimkhani, Fiona Oakley, Lindsay B. Murphy, Jelena Mann, Anna Moles, et al.. Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.. Nature Medicine, Nature Publishing Group, 2011, 17 (12), pp.1668-73. ⟨10.1038/nm.2490⟩. ⟨inserm-00652584⟩
  • Silvina Laura Diaz, Luc Maroteaux. Implication of 5-HT(2B) receptors in the serotonin syndrome.. Neuropharmacology, Elsevier, 2011, 61 (3), pp.495-502. ⟨10.1016/j.neuropharm.2011.01.025⟩. ⟨inserm-00561473⟩
  • Clara Dees, Alfiya Akhmetshina, Pawel Zerr, Nicole Reich, Katrin Palumbo, et al.. Platelet-derived serotonin links vascular disease and tissue fibrosis.: Serotonin in 5-HT2B fibrotic disease. Journal of Experimental Medicine, Rockefeller University Press, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩. ⟨inserm-00589662⟩
  • Laurent Monassier, Marc André Laplante, Tarak Ayadi, Stéphane Doly, Luc Maroteaux. Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotonin.. Pharmacology and Therapeutics, Elsevier, 2010, 128 (3), pp.559-67. ⟨10.1016/j.pharmthera.2010.08.004⟩. ⟨inserm-00549197v2⟩
  • V. S. Tharayil, M. M. Wouters, J. E. Stanich, J. L. Roeder, S. Lei, et al.. Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.. Neurogastroenterology & Motility, Wiley, 2010, 22 (4), pp.462-9, e109-10. ⟨10.1111/j.1365-2982.2009.01435.x⟩. ⟨inserm-00996753⟩
  • Laura Bevilacqua, Stéphane Doly, Jaakko Kaprio, Qiaoping Yuan, Roope Tikkanen, et al.. A population-specific HTR2B stop codon predisposes to severe impulsivity.. Nature, Nature Publishing Group, 2010, 468 (7327), pp.1061-6. ⟨10.1038/nature09629⟩. ⟨inserm-00550376⟩
  • Fabrice Jaffré, Philippe Bonnin, Jacques Callebert, Haythem Debbabi, Vincent Setola, et al.. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.. Circulation Research, American Heart Association, 2009, 104 (1), pp.113-23. ⟨10.1161/CIRCRESAHA.108.180976⟩. ⟨inserm-00484528⟩
  • Stéphane Doly, Jesus Bertran-Gonzalez, Jacques Callebert, Alexandra Bruneau, Sophie Marie Banas, et al.. Role of serotonin via 5-HT2B receptors in the reinforcing effects of MDMA in mice.. PLoS ONE, Public Library of Science, 2009, 4 (11), pp.e7952. ⟨10.1371/journal.pone.0007952⟩. ⟨inserm-00484504⟩
  • Corinne Collet, Corinne Schiltz, Valérie Geoffroy, Luc Maroteaux, Jean-Marie Launay, et al.. The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation.. FASEB Journal, Federation of American Society of Experimental Biology, 2008, 22 (2), pp.418-27. ⟨10.1096/fj.07-9209com⟩. ⟨inserm-00996758⟩
  • Stéphane Doly, Emmanuel Valjent, Vincent Setola, Jacques Callebert, Denis Hervé, et al.. Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro.. Journal of Neuroscience, Society for Neuroscience, 2008, 28 (11), pp.2933-40. ⟨10.1523/JNEUROSCI.5723-07.2008⟩. ⟨inserm-00484533⟩
  • Laurent Monassier, Marc-André Laplante, Fabrice Jaffré, Pascal Bousquet, Luc Maroteaux, et al.. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.. Hypertension, American Heart Association, 2008, 52 (2), pp.301-7. ⟨10.1161/HYPERTENSIONAHA.107.105551⟩. ⟨inserm-00484531⟩
  • Agnès Janoshazi, Maud Deraet, Jacques Callebert, Vincent Setola, Silke Guenther, et al.. Modified Receptor Internalization upon Co-expression of 5-HT1B Receptor and 5-HT2B Receptors.. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 71 (6), pp.1463-74. ⟨10.1124/mol.106.032656⟩. ⟨hal-00135110⟩
  • B Schaerlinger, J M Launay, J L Vonesch, Luc Maroteaux. Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation.. Developmental Dynamics, Wiley, 2007, 236 (4), pp.991-999. ⟨10.1002/dvdy.21110⟩. ⟨hal-01274920⟩
  • J Callebert, J M Esteve, P Hervé, K Peoc'H, C Tournois, et al.. Evidence for a control of plasma serotonin levels by 5-hydroxytryptamine(2B) receptors in mice.. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2006, 317 (2), pp.724-731. ⟨10.1124/jpet.105.098269⟩. ⟨hal-01274937⟩
  • Silke Günther, Luc Maroteaux, Stephan W. Schwarzacher. Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro. Journal of Neurobiology, Wiley, 2006, 66 (9), pp.949-961. ⟨10.1002/neu.20253⟩. ⟨hal-01274950⟩
  • Juan M Esteve, Jean-Marie Launay, Odile Kellermann, Luc Maroteaux. Functions of serotonin in hypoxic pulmonary vascular remodeling.. Cell Biochemistry and Biophysics, Humana Press, 2006, 47 (1), pp.33-44. ⟨10.1385/CBB:47:1:33⟩. ⟨hal-01274919⟩
  • Maud Deraet, Philippe Manivet, Agnes Janoshazi, Jacques Callebert, Silke Guenther, et al.. The Natural Mutation Encoding a C Terminus-Truncated 5-Hydroxytryptamine2B Receptor Is a Gain of Proliferative Functions. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2005, 67 (4), pp.983 - 991. ⟨10.1124/mol.104.008268⟩. ⟨hal-01596608⟩
  • Nelly Etienne, Bérénice Schaerlinger, Fabrice Jaffré, Luc Maroteaux. Le récepteur 5-HT2B: une cible privilégiée de la sérotonine au niveau cardio-pulmonaire. Journal de la Société de Biologie, 2004, 198 (1), pp.22-9. ⟨hal-01274957⟩
  • Fabrice Jaffré, Jacques Callebert, Alexandre Sarre, Nelly Etienne, Canan G Nebigil, et al.. Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts.. Circulation, American Heart Association, 2004, 110 (8), pp.969-974. ⟨10.1161/01.CIR.0000139856.20505.57⟩. ⟨hal-01274954⟩
  • Patricia Gaspar, Olivier Cases, Luc Maroteaux. The developmental role of serotonin: news from mouse molecular genetics.. Nature Reviews Neuroscience, Nature Publishing Group, 2003, 4 (12), pp.1002-12. ⟨10.1038/nrn1256⟩. ⟨hal-01274960⟩
  • Canan G Nebigil, Nelly Etienne, Nadia Messaddeq, Luc Maroteaux. Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT 2B receptor signaling. FASEB Journal, Federation of American Society of Experimental Biology, 2003, 17 (10), pp.1373-1375. ⟨10.1096/fj.02-1122fje⟩. ⟨hal-01985091⟩
  • L Launay, P. Herve, K. Peoc'H, C. Tournois, C Callebert, et al.. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nature Medicine, Nature Publishing Group, 2002, 8 (10), pp.1129-1135. ⟨10.1038/nm764⟩. ⟨hal-01985063⟩
  • C.G. Nebigil, N. Etienne, B. Schaerlinger, P. Hickel, J.‐m. Launay, et al.. DEVELOPMENTALLY REGULATED SEROTONIN 5-HT 2B RECEPTORS. International Journal of Developmental Neuroscience, Elsevier, 2001, 19 (4), pp.365-372. ⟨10.1016/s0736-5748(01)00022-3⟩. ⟨hal-03721220⟩
  • Canan G Nebigil, Pierre Hickel, Nadia Messaddeq, Jean-Luc Vonesch, Marie P Douchet, et al.. Ablation of serotonin 5-HT 2B receptors in mice leads to abnormal cardiac structure and function. Circulation, American Heart Association, 2001, 103 (24), pp.2973-2979. ⟨10.1161/01.cir.103.24.2973⟩. ⟨hal-03721232⟩
  • Canan G Nebigil, Luc Maroteaux. Functional consequence of serotonin/5-HT2B receptor signaling in heart: A role of mitochondria for transition between hypertrophy and heart failure?. Trends in Cardiovascular Medicine, Elsevier, 2001, 11 (8), pp.329-335. ⟨10.1016/s1050-1738(01)00135-9⟩. ⟨hal-03721187⟩
  • Canan G Nebigil, D.-S. Choi, André Dierich, Pierre Hickel, Marianne Le Meur, et al.. Serotonin 2B receptor is required for heart development. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2000, 97 (17), pp.9508-9513. ⟨10.1073/pnas.97.17.9508⟩. ⟨hal-02926424⟩
  • Canan G Nebigil, J.-M. Launay, Pierre Hickel, C. Tournois, Luc Maroteaux. 5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2000, 97 (6), pp.2591-2596. ⟨10.1073/pnas.050282397⟩. ⟨hal-02926507⟩
  • D S Choi, Odile Kellermann, S Richard, J F Colas, Francisco Bolaños-Jiménez, et al.. Mouse 5-HT2B receptor-mediated serotonin trophic functions.. Annals of the New York Academy of Sciences, Wiley, 1998, 861, pp.67-73. ⟨10.1111/j.1749-6632.1998.tb10174.x⟩. ⟨hal-02693974⟩
  • Francisco Bolaños-Jiménez, D S Choi, L Maroteaux. Preferential expression of 5-HT1D over 5-HT1B receptors during murine embryonic development.. Annals of the New York Academy of Sciences, Wiley, 1998, 861, pp.238-239. ⟨10.1111/j.1749-6632.1998.tb10198.x⟩. ⟨hal-02690436⟩
  • Jean-François Colas, D.-S. Choi, Jean-Marie Launay, Luc Maroteaux. Evolutionary conservation of the 5-HT 2B receptors. Annals of the New York Academy of Sciences, Wiley, 1997, 812 (1 Receptor Clas), pp.149-153. ⟨10.1111/j.1749-6632.1997.tb48157.x⟩. ⟨hal-03721324⟩
  • Doo-Sup Choi, Simon J Ward, Nadia Messaddeq, Jean-Marie Launay, Luc Maroteaux. 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.. Development (Cambridge, England), Company of Biologists, 1997, 124 (9), pp.1745-55. ⟨hal-02926362⟩
  • Francisco Bolaños-Jiménez, D S Choi, L Maroteaux. Preferential expression of 5-HT1D over 5-HT1B receptors during early embryogenesis.. NeuroReport, Lippincott, Williams & Wilkins, 1997, 8 (17), pp.3655-3660. ⟨10.1097/00001756-199712010-00001⟩. ⟨hal-02696479⟩
  • Maryvonne Le Coniat, Doo-Sup Choi, Luc Maroteaux, Jean-Marie Launay, Roland Berger. The 5-HT2B Receptor Gene Maps to 2q36.3–2q37.1. Genomics, Elsevier, 1996, 32 (1), pp.172-173. ⟨10.1006/geno.1996.0101⟩. ⟨hal-03721346⟩

Books1 document

Book sections4 documents