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Dopamine D2 long receptors are critical for caveolae-mediated $\alpha$-synuclein uptake in cultured dopaminergic neurons

Ichiro Kawahata , Tomoki Sekimori , Haoyang Wang , Yanyan Wang , Toshikuni Sasaoka , et al.
Biomedicines, 2021, 9, pp.49. ⟨10.3390/biomedicines9010049⟩
Article dans une revue cea-03116063v1

Effect of tolytoxin on tunneling nanotube formation and function

Aysegul Dilsizoglu Senol , Anna Pepe , Clara Grudina , Nathalie Sassoon , Ueoka Reiko , et al.
Scientific Reports, 2019, 9 (1), pp.5741. ⟨10.1038/s41598-019-42161-6⟩
Article dans une revue pasteur-02263619v1

Hsc70 protein interaction with soluble and fibrillar alpha-synuclein.

Samantha Pemberton , Karine Madiona , Laura Pieri , Mehdi Kabani , Luc Bousset , et al.
Journal of Biological Chemistry, 2011, 286 (40), pp.34690-9. ⟨10.1074/jbc.M111.261321⟩
Article dans une revue hal-01183175v1

The role of Galectin-3 in α-synuclein-induced microglial activation.

Antonio Boza-Serrano , Juan F Reyes , Nolwen L Rey , Hakon Leffler , Luc Bousset , et al.
Acta Neuropathologica Communications, 2013, 2, pp.156. ⟨10.1186/s40478-014-0156-0⟩
Article dans une revue hal-01183754v1
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Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

Meryem Tardivel , Séverine Bégard , Luc Bousset , Simon Dujardin , Audrey Coens , et al.
Acta Neuropathologica Communications, 2016, 4 (1), pp.117. ⟨10.1186/s40478-016-0386-4⟩
Article dans une revue inserm-01391925v1

Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein

Ali Makky , Luc Bousset , Jérôme Polesel-Maris , Ronald Melki
Scientific Reports, 2016, 6, pp.37970. ⟨10.1038/srep37970⟩
Article dans une revue hal-01410315v1

The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

Jeshlee Vijayakumar , Charlène Perrois , Marjorie Heim , Luc Bousset , Simon Alberti , et al.
Nature Communications, 2019, 10 (1), pp.2593. ⟨10.1038/s41467-019-10554-w⟩
Article dans une revue cea-02279233v1

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms

Maria Masnata , Giacomo Sciacca , Alexander Maxan , Luc Bousset , Hélèna Denis , et al.
Acta Neuropathologica, 2019, 137 (6), pp.981-1001. ⟨10.1007/s00401-019-01973-6⟩
Article dans une revue cea-02279743v1

Assessment of the efficacy of different procedures that remove and disassemble alpha-synuclein, tau and A-beta fibrils from laboratory material and surfaces

Alexis Fenyi , Audrey Coens , Tracy Bellande , Ronald Melki , Luc Bousset
Scientific Reports, 2018, 8 (1), pp.10788. ⟨10.1038/s41598-018-28856-2⟩
Article dans une revue hal-01871856v1

Structure of the prion Ure2p in protein fibrils assembled in vitro.

Nicolas Fay , Virginie Redeker , Jimmy Savistchenko , Steven Dubois , Luc Bousset , et al.
Journal of Biological Chemistry, 2005, 280 (44), pp.37149-58. ⟨10.1074/jbc.M506917200⟩
Article dans une revue hal-01183840v1

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.

William P Flavin , Luc Bousset , Zachary C Green , Yaping Chu , Stratos Skarpathiotis , et al.
Acta Neuropathologica, 2017, 134 (4), pp.629-653. ⟨10.1007/s00401-017-1722-x⟩
Article dans une revue hal-01571238v1

Binding, internalization and fate of Huntingtin Exon1 fibrillar assemblies in mitotic and non-mitotic neuroblastoma cells.

Gemma Ruiz-Arlandis , Laura Pieri , Luc Bousset , Ronald Melki
Neuropathology and Applied Neurobiology, 2016, 42 (2), pp.137-152. ⟨10.1111/nan.12258⟩
Article dans une revue istex hal-01179133v1

The conformation of the prion domain of Sup35p in isolation and in the full-length protein.

Nina Luckgei , Anne K Schütz , Luc Bousset , Birgit Habenstein , Yannick Sourigues , et al.
Angewandte Chemie International Edition, 2013, 52 (48), pp.12741-4. ⟨10.1002/anie.201304699⟩
Article dans une revue istex hal-01183045v1

Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells.

Laura Pieri , Karine Madiona , Luc Bousset , Ronald Melki
Biophysical Journal, 2012, 102 (12), pp.2894-905. ⟨10.1016/j.bpj.2012.04.050⟩
Article dans une revue hal-01183141v1

Solid-state NMR sequential assignments of α-synuclein.

Julia Gath , Birgit Habenstein , Luc Bousset , Ronald Melki , Beat H Meier , et al.
Biomolecular NMR Assignments, 2012, 6 (1), pp.51-5. ⟨10.1007/s12104-011-9324-3⟩
Article dans une revue hal-01183147v1

Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice.

Nolwen L Rey , Geraldine H Petit , Luc Bousset , Ronald Melki , Patrik Brundin
Acta Neuropathologica, 2013, 126 (4), pp.555-73. ⟨10.1007/s00401-013-1160-3⟩
Article dans une revue hal-01183050v1

A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.

Cécile Caubet , Luc Bousset , Ole Clemmensen , Yannick Sourigues , Anette Bygum , et al.
FASEB Journal, 2010, 24 (9), pp.3416-26. ⟨10.1096/fj.10-155622⟩
Article dans une revue hal-01183203v1

Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.

Dominique Bétemps , Jérémy Verchère , Sébastien Brot , Eric Morignat , Luc Bousset , et al.
Acta Neuropathologica Communications, 2013, 2, pp.29. ⟨10.1186/2051-5960-2-29⟩
Article dans une revue hal-01183383v1
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Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectrometry.

Amulya Nidhi Shrivastava , Virginie Redeker , Nicolas Fritz , Laura Pieri , Leandro G Almeida , et al.
Data in Brief, 2016, 7, pp.221-8. ⟨10.1016/j.dib.2016.02.018⟩
Article dans une revue hal-01305431v1

LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

Gregor Bieri , Michel Brahic , Luc Bousset , Julien Couthouis , Nicholas Kramer , et al.
Acta Neuropathologica, 2019, 137 (6), pp.961-980. ⟨10.1007/s00401-019-01995-0⟩
Article dans une revue cea-02279704v1
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α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb

Nolwen Rey , Luc Bousset , Sonia George , Zachary Madaj , Lindsay Meyerdirk , et al.
Acta Neuropathologica Communications, 2019, 7 (1), pp.221. ⟨10.1186/s40478-019-0859-3⟩
Article dans une revue cea-02426346v1

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

Magnus E Jakobsson , Anders Moen , Luc Bousset , Wolfgang Egge-Jacobsen , Stefan Kernstock , et al.
Journal of Biological Chemistry, 2013, 288 (39), pp.27752-63. ⟨10.1074/jbc.M113.483248⟩
Article dans une revue hal-01183055v1

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.

Staffan Holmqvist , Oldriska Chutna , Luc Bousset , Patrick Aldrin-Kirk , Wen Li , et al.
Acta Neuropathologica, 2014, 128 (6), pp.805-20. ⟨10.1007/s00401-014-1343-6⟩
Article dans une revue hal-01155404v1

Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion.

Birgit Habenstein , Christian Wasmer , Luc Bousset , Yannick Sourigues , Anne Schütz , et al.
Journal of Biomolecular NMR, 2011, 51 (3), pp.235-43. ⟨10.1007/s10858-011-9530-4⟩
Article dans une revue hal-01183172v1

Hydrogen/Deuterium exchange mass spectrometric analysis of conformational changes accompanying the assembly of the yeast prion ure2p into protein fibrils.

Virginie Redeker , Frédéric Halgand , Jean-Pierre Le Caer , Luc Bousset , Olivier Laprévote , et al.
Journal of Molecular Biology, 2007, 369 (4), pp.1113-25. ⟨10.1016/j.jmb.2007.04.018⟩
Article dans une revue istex hal-00157361v1
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$\alpha$‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities

Parvez Alam , Luc Bousset , Ronald Melki , Daniel Otzen
Journal of Neurochemistry, 2019, 150 (5), pp.522-534. ⟨10.1111/jnc.14808⟩
Article dans une revue cea-02279218v1
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Prion amyloid polymorphs -The tag might change it all

Luc Bousset , Nina Luckgei , Mehdi Kabani , Carole Gardiennet , Anne Schütz , et al.
Frontiers in Molecular Biosciences, 2020, 7, pp.190. ⟨10.3389/fmolb.2020.00190⟩
Article dans une revue cea-02912510v1
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Clustering of Tau fibrils impairs the synaptic composition of $\alpha$3‐Na$^+$/K$^+$‐ATP ase and AMPA receptors

Amulya Nidhi Shrivastava , Virginie Redeker , Laura Pieri , Luc Bousset , Marianne Renner , et al.
EMBO Journal, 2019, 38 (3), pp.e99871. ⟨10.15252/embj.201899871⟩
Article dans une revue cea-02279806v1
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Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network

Simona Gribaudo , Philippe Tixador , Luc Bousset , Alexis Fenyi , Patricia Lino , et al.
Stem Cell Reports, 2019, 12 (2), pp.230-244. ⟨10.1016/j.stemcr.2018.12.007⟩
Article dans une revue hal-02050472v1

Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease

Veselin Grozdanov , Luc Bousset , Meike Hoffmeister , Corinna Bliederhaeuser , Christoph Meier , et al.
Annals of Neurology, 2019, ⟨10.1002/ana.25557⟩
Article dans une revue cea-02279195v1