|
Evolution of the Envelope Glycoprotein of HIV-1 Clade B toward Higher Infectious Properties over the Course of the Epidemic
Mélanie Bouvin-Pley
,
Maxime Beretta
,
Moreau Alain
,
Emmanuelle Roch
,
Asma Essat
Article dans une revue
hal-02531055v1
|
|
Interdomain stabilization impairs CD4 binding and improves immunogenicity of the HIV-1 envelope trimer
Peng Zhang
,
Jason Gorman
,
Hui Geng
,
Qingbo Liu
,
Yin Lin
Article dans une revue
hal-02531048v1
|
|
Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site
Willy Bogers
,
Susan W Barnett
,
Herman Oostermeijer
,
Ivonne Nieuwenhuis
,
Niels Beenhakker
Article dans une revue
hal-02530939v1
|
|
Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques
Xiaoying Shen
,
Willy Bogers
,
Nicole Yates
,
Guido Ferrari
,
Antu Dey
Article dans une revue
hal-02530935v1
|
|
M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures
Giuseppina Musumeci
,
Isabella Bon
,
David Lembo
,
Valeria Cagno
,
Maria Carla Re
Article dans une revue
hal-02530919v1
|
|
Targeting the late stage of HIV-1 entry for antibody-dependent cellular cytotoxicity: structural basis for Env epitopes in the C11 region
William Tolbert
,
Neelakshi Gohain
,
Nirmin Alsahafi
,
Verna Van
,
Chiara Orlandi
Article dans une revue
hal-02531052v1
|
|
Co-receptor binding site antibodies enable CD4-mimetics to expose conserved anti-cluster A ADCC epitopes on HIV-1 envelope glycoproteins
Jonathan Richard
,
Beatriz Pacheco
,
Neelakshi Gohain
,
Maxime Veillette
,
Shilei Ding
Article dans une revue
hal-02530909v1
|
|
Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1
Neelakshi Gohain
,
William Tolbert
,
Priyamvada Acharya
,
Lei Yu
,
Tongyun Liu
Article dans une revue
hal-02530901v1
|
|
Thermosensitive and mucoadhesive pluronic-hydroxypropylmethylcellulose hydrogel containing the mini-CD4 M48U1 Is a promising efficient barrier against HIV diffusion through macaque Cervicovaginal Mucus
Kawthar Bouchemal
,
Armelle Aka-Any-Grah
,
Nathalie Dereuddre-Bosquet
,
Loïc M Martin
,
Vanessa Lievin-Le-Moal
Article dans une revue
cea-02530843v1
|
|
Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas
Hannah Barbian
,
Julie Decker
,
Frederic Bibollet-Ruche
,
Rachel Galimidi
,
Anthony West
Article dans une revue
cea-02530869v1
|
|
Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops
Carlos G. Moscoso
,
Li Xing
,
Jinwen Hui
,
Jeffrey Hu
,
Mohammad Baikoghli Kalkhoran
Article dans une revue
cea-02530807v1
|
|
CD4 mimetics sensitize HIV-1-infected cells to ADCC
Jonathan Richard
,
Maxime Veillette
,
Nathalie Brassard
,
Shilpa Iyer
,
Michel Roger
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (20), pp.E2687-E2694. ⟨10.1073/pnas.1506755112⟩
Article dans une revue
hal-02530884v1
|
|
Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection
P. Acharya
,
W. Tolbert
,
N. Gohain
,
X. Wu
,
Linwen Yu
Article dans une revue
cea-02530781v1
|
|
Combinations of Entry and Reverse Transcriptase Inhibitors as Candidate Microbicides
Carolina Herrera
,
Natalia Olejniczak
,
Javier García Pérez
,
Jose Alcami
,
Loïc M Martin
Article dans une revue
hal-02542966v1
|
|
Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1
Priyamvada Acharya
,
Timothy S. Luongo
,
Mark k. Louder
,
Krisha Mckee
,
Yongping Yang
Article dans une revue
hal-02530653v1
|
|
Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide
Kawthar Bouchemal
,
Justyna Frelichowska
,
Loïc M Martin
,
Vanessa Liévin-Le Moal
,
Roger Le Grand
Article dans une revue
hal-02530642v1
|
|
Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites
P. Acharya
,
T. Luongo
,
I. Georgiev
,
J. Matz
,
S. Schmidt
Article dans une revue
hal-02530765v1
|
|
M48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding
Philippe Selhorst
,
Katrijn Grupping
,
Tommy Tong
,
Ema Crooks
,
Loïc M Martin
Article dans une revue
hal-02542962v1
|
|
Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein
Laurence Morellato-Castillo
,
Priyamvada Acharya
,
Olivier Combes
,
Johan Michiels
,
Anne Descours
Article dans une revue
hal-02530667v1
|
|
RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans
N. Suffee
,
H. Hlawaty
,
A. Meddahi-Pelle
,
L. Maillard
,
L. Louedec
Article dans une revue
cea-02530559v1
|
|
Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization
Priyamvada Acharya
,
Timothy S. Luongo
,
Julie Matz
,
Stephen D. Schmidt
,
Gwo-Yu Chuang
Retrovirology, 2012, 9 (Suppl 2), pp.P346
Article dans une revue
inserm-00731776v1
|
|
MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques
Nathalie Dereuddre-Bosquet
,
Laurence Morellato-Castillo
,
Joachim Brouwers
,
Patrick Augustijns
,
Kawthar Bouchemal
Article dans une revue
cea-02530573v1
|
|
Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120
J. Matz
,
P. Kessler
,
J. Bouchet
,
O. Combes
,
O. Ramos
Article dans une revue
cea-02530610v1
|
|
Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein
Antu Dey
,
Brian Burke
,
Yide Sun
,
Klara Sirokman
,
Avishek Nandi
Article dans une revue
cea-02530537v1
|
|
MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency
Katrijn Grupping
,
Philippe Selhorst
,
Johan Michiels
,
Katleen Vereecken
,
Leo Heyndrickx
Article dans une revue
cea-02530546v1
|
|
Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120
Julie Matz
,
Pacal Kessler
,
Jérome Bouchet
,
Olivier Combes
,
Daniel Baty
Retrovirology, 2012, 9 (Suppl 2), pp.P214
Article dans une revue
inserm-00731772v1
|
|
Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry
Priyamvada Acharya
,
Cajetan Dogo-Isonagie
,
Judith Lalonde
,
Son Lam
,
George Leslie
Article dans une revue
cea-02530519v1
|
|
Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic
Grégoire Martin
,
Brian Burke
,
Robert Thai
,
Antu Dey
,
Olivier Combes
Journal of Biological Chemistry, 2011, 286 (24), pp.21706-21716
Article dans une revue
cea-01989703v1
|
|
Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding
C. Moscoso
,
Y. Sun
,
S. Poon
,
L. Xing
,
E. Kan
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (15), pp.6091-6096. ⟨10.1073/pnas.1016113108⟩
Article dans une revue
cea-02530515v1
|
|
Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells
Maylis Dagouassat
,
Nadine Suffee
,
Hanna Hlawaty
,
Oualid Haddad
,
Faten Charni
Article dans une revue
cea-02529147v1
|
|
Resistance to the CD4 mimetic mini protein M48-U1 induces changes in a highly conserved region on the HIV-1 gp120 envelope protein
K Grupping
,
L. Heyndrickx
,
J. Michiels
,
G. Martin
,
Loïc M Martin
Article dans une revue
hal-02542981v1
|
|
Syndecan-1 and syndecan-4 are involved in RANTES/CCL5-induced migration and invasion of human hepatoma cells
Faten Charni
,
Véronique Friand
,
Oualid Haddad
,
Hanna Hlawaty
,
Loïc M Martin
Article dans une revue
cea-02529135v1
|
|
A global benchmark study using affinity-based biosensors
Rebecca L. Rich
,
Giuseppe A. Papalia
,
Peter J. Flynn
,
Jamie Furneisen
,
John Quinn
Article dans une revue
hal-01527917v1
|
|
P19-23. Putative prefusion mechanism of HIV-1 Env revealed by ligand-induced quaternary alterations in o-gp140 trimers
Cg Moscoso
,
E Kan
,
S Poon
,
Y. Sun
,
Loïc M Martin
Article dans une revue
hal-02542974v1
|
|
Structural Studies of the Complex Between Akt-in and the Akt2-PH Domain Suggest that the Peptide Acts as an Allosteric Inhibitor of the Akt Kinase
Virginie Ropars
,
Philippe Barthe
,
Chi-Shien Wang
,
Wenlung Chen
,
Der-Lii Tzou
Article dans une revue
hal-02543033v1
|
|
A simple one-step method for the preparation of HIV-1 envelope glycoprotein immunogens based on a CD4 mimic peptide
Grégoire Martin
,
Yide Sun
,
Bernadette Heyd
,
Olivier Combes
,
Jeffrey Ulmer
Article dans une revue
hal-02528592v1
|
|
Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein
François Stricher
,
Chih-Chin Huang
,
Anne Descours
,
Sophie Duquesnoy
,
Olivier Combes
Article dans une revue
hal-02528576v1
|
|
Glycosaminoglycans and their synthetic mimetics inhibit RANTES-induced migration and invasion of human hepatoma cells.
Angela Sutton
,
Veronique Friand
,
Dulce Papy-Garcia
,
Maylis Dagouassat
,
Loïc M Martin
Article dans une revue
hal-00195453v1
|
|
Scorpion-Toxin Mimics of CD4 in Complex with Human Immunodeficiency Virus gp120
Chih-Chin Huang
,
François Stricher
,
Loïc M Martin
,
Julie Decker
,
Shahzad Majeed
Article dans une revue
hal-02528561v1
|
|
A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic
François Stricher
,
Loïc M Martin
,
Philippe Barthe
,
Vivian Pogenberg
,
Alain Mechulam
Article dans une revue
hal-02528566v1
|
|
Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope † , ‡
Ramalakshmi Darbha
,
Sanjay Phogat
,
Aran Labrijn
,
Yuuei Shu
,
Yijun Gu
Article dans une revue
hal-02543015v1
|
|
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
Loïc M Martin
,
François Stricher
,
Dorothée Missé
,
Francesca Sironi
,
Martine Pugnière
Article dans une revue
hal-02528557v1
|
|
Synthesis and characterization of biologically functional biotinylated RANTES
Claudio Vita
,
Eugenia Drakopoulou
,
Loyda Ylisastigui
,
Youssef Bakri
,
Jean Vizzavona
Article dans une revue
hal-02528550v1
|
|
Heparin-aggregated RANTES can be crystallised.
Enrico A Stura
,
Loïc M Martin
,
Hugues Lortat-Jacob
,
Romain R Vivès
,
Claudio Vita
Acta crystallographica Section D : Structural biology [1993-..], 2002, 58 (Pt 10 Pt 1), pp.1670-3
Article dans une revue
hal-01061424v1
|
|
Role of Disulfide Bonds in Folding and Activity of Leiurotoxin I: Just Two Disulfides Suffice
Qi Zhu
,
Songping Liang
,
Loïc M Martin
,
Sylvaine Gasparini
,
André Ménez
Article dans une revue
hal-02528546v1
|
|
Solid-phase synthesis of peptides containing the spin-labeled 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid (TOAC)
Loïc M Martin
,
C. Vita
,
A. Ivancich
,
F. Formaggio
,
C. Toniolo
Article dans une revue
hal-02543003v1
|
|
Structural and Functional Analysis of the RANTES-Glycosaminoglycans Interactions
Loïc M Martin
,
Cédric Blanpain
,
Pascale Garnier
,
Valérie Wittamer
,
Marc Parmentier
Article dans une revue
hal-02528544v1
|
|
Engineering Novel Bioactive Mini-Proteins from Small Size Natural and De Novo Designed Scaffolds
Loïc M Martin
,
Claudio Vita
Article dans une revue
hal-02543052v1
|
|
Engineering Novel Bioactive Mini-Proteins on Natural Scaffolds
Loïc M Martin
,
Philipe Barthe
,
Olivier Combes
,
Christian Roumestand
,
Claudio Vita
Article dans une revue
hal-02528540v1
|
|
Metallopeptidase Inhibitors of Tetanus Toxin: A Combinatorial Approach
Loïc M Martin
,
Fabrice Cornille
,
Serge Turcaud
,
Hervé Meudal
,
Bernard P. Roques
Article dans une revue
hal-02528535v1
|
|
β-Amino-thiols Inhibit the Zinc Metallopeptidase Activity of Tetanus Toxin Light Chain
Loïc M Martin
,
Fabrice Cornille
,
Pascale Coric
,
Bernard P. Roques
,
Marie-Claude Fournie-Zaluski
Article dans une revue
hal-02461413v1
|
|
Cooperative Exosite-dependent Cleavage of Synaptobrevin by Tetanus Toxin Light Chain
Fabrice Cornille
,
Loïc M Martin
,
Christine Lenoir
,
Didier Cussac
,
Bernard P. Roques
Article dans une revue
hal-02528515v1
|
|
Allosteric-type control of synaptobrevin cleavage by tetanus toxin light chain
Fabrice Cornille
,
Loïc M Martin
,
Christine Lenoir
,
Didier Cussac
,
Bernard P. Roques
Article dans une revue
hal-02528513v1
|
|
2,4-Dinitrophenyl 4-Methoxybenzyl Disulfide: A New Efficient Reagent for the Electrophilic Sulfenylation of β-Amino Ester Enolates
Laurent Bischoff
,
Christelle David
,
Loïc M Martin
,
Hervé Meudal
,
Bernard-Pierre Roques
Article dans une revue
hal-02122111v1
|
|
A Sensitive and Rapid Fluorescence-Based Assay for Determination of Tetanus Toxin Peptidase Activity
Jean-Marc Soleilhac
,
Fabrice Cornille
,
Loïc M Martin
,
Christine Lenoir
,
Marie-Claude Fournié-Zaluski
Article dans une revue
hal-02528509v1
|