Accéder directement au contenu

Loic MARTIN

7
Documents

Présentation

https://orcid.org/0000-0002-7940-2955 ResearcherID : E-1627-2011 ------------------------------------------------------------------ Group leader in Biochemistry, Molecular Biology, Drug Design at CEA Saclay / DRF / Joliot institute / DMTS / SIMoS

Publications

759013

Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein

Laurence Morellato-Castillo , Priyamvada Acharya , Olivier Combes , Johan Michiels , Anne Descours
Journal of Medicinal Chemistry, 2013, 56 (12), pp.5033-5047. ⟨10.1021/jm4002988⟩
Article dans une revue hal-02530667v1

Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

Priyamvada Acharya , Timothy S. Luongo , Mark k. Louder , Krisha Mckee , Yongping Yang
Structure, 2013, 21 (6), pp.1018-1029. ⟨10.1016/j.str.2013.04.015⟩
Article dans une revue hal-02530653v1

Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein

Antu Dey , Brian Burke , Yide Sun , Klara Sirokman , Avishek Nandi
PLoS ONE, 2012, 7 (1), pp.e30233. ⟨10.1371/journal.pone.0030233⟩
Article dans une revue cea-02530537v1

MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques

Nathalie Dereuddre-Bosquet , Laurence Morellato-Castillo , Joachim Brouwers , Patrick Augustijns , Kawthar Bouchemal
PLoS Pathogens, 2012, 8 (12), pp.e1003071. ⟨10.1371/journal.ppat.1003071⟩
Article dans une revue cea-02530573v1
Image document

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

Priyamvada Acharya , Timothy S. Luongo , Julie Matz , Stephen D. Schmidt , Gwo-Yu Chuang
Retrovirology, 2012, 9 (Suppl 2), pp.P346
Article dans une revue inserm-00731776v1

MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency

Katrijn Grupping , Philippe Selhorst , Johan Michiels , Katleen Vereecken , Leo Heyndrickx
Retrovirology, 2012, 9 (1), pp.36. ⟨10.1186/1742-4690-9-36⟩
Article dans une revue cea-02530546v1

Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic

Grégoire Martin , Brian Burke , Robert Thai , Antu Dey , Olivier Combes
Journal of Biological Chemistry, 2011, 286 (24), pp.21706-21716
Article dans une revue cea-01989703v1