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Number of documents

58

Group leader in Biochemistry, Molecular Biology, Drug Design at CEA Saclay / DRF / Joliot institute / DMTS / SIMoS (FRANCE)


https://orcid.org/0000-0002-7940-2955
ResearcherID : E-1627-2011

Group leader in Biochemistry, Molecular Biology, Drug Design at CEA Saclay / DRF / Joliot institute / DMTS / SIMoS


Journal articles57 documents

  • Loïc Martin, Caroline Simonucci, Sétareh Rad, Marc F. Benedetti. Effect of natural organic matter on thallium and silver speciation. Journal of Environmental Sciences, Elsevier, 2020, 93, pp.185-192. ⟨10.1016/j.jes.2020.04.001⟩. ⟨hal-02565435⟩
  • Sebastian Kreutzer, Chantal Tribolo, Loïc Martin, Norbert Mercier. Dose-Rate Estimation using alpha-Al2O3:C Chips: Aftermath. Ancient TL, Luminescence Dosimetry Laboratory, 2020, 38 (1), pp.1-10. ⟨hal-02897823⟩
  • Mélanie Bouvin-Pley, Maxime Beretta, Moreau Alain, Emmanuelle Roch, Asma Essat, et al.. Evolution of the Envelope Glycoprotein of HIV-1 Clade B toward Higher Infectious Properties over the Course of the Epidemic. Journal of Virology, American Society for Microbiology, 2019, 93 (6), pp.1-15. ⟨10.1128/JVI.01171-18⟩. ⟨hal-02531055⟩
  • Peng Zhang, Jason Gorman, Hui Geng, Qingbo Liu, Yin Lin, et al.. Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer. Cell Host and Microbe, Elsevier, 2018, 23 (6), pp.832-844.e6. ⟨10.1016/j.chom.2018.05.002⟩. ⟨hal-02531048⟩
  • Willy Bogers, Susan Barnett, Herman Oostermeijer, Ivonne Nieuwenhuis, Niels Beenhakker, et al.. Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site. Journal of Virology, American Society for Microbiology, 2017, 91 (19), ⟨10.1128/JVI.00811-17⟩. ⟨hal-02530939⟩
  • Xiaoying Shen, Willy Bogers, Nicole Yates, Guido Ferrari, Antu Dey, et al.. Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques. Journal of Virology, American Society for Microbiology, 2017, 91 (19), ⟨10.1128/JVI.00401-17⟩. ⟨hal-02530935⟩
  • William Tolbert, Neelakshi Gohain, Nirmin Alsahafi, Verna Van, Chiara Orlandi, et al.. Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region. Structure, Elsevier (Cell Press), 2017, 25 (11), pp.1719-1731.e4. ⟨10.1016/j.str.2017.09.009⟩. ⟨hal-02531052⟩
  • Giuseppina Musumeci, Isabella Bon, David Lembo, Valeria Cagno, Maria Carla Re, et al.. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/srep41018⟩. ⟨hal-02530919⟩
  • Jonathan Richard, Beatriz Pacheco, Neelakshi Gohain, Maxime Veillette, Shilei Ding, et al.. Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins. EBioMedicine, Elsevier, 2016, 12, pp.208-218. ⟨10.1016/j.ebiom.2016.09.004⟩. ⟨hal-02530909⟩
  • Neelakshi Gohain, William Tolbert, Priyamvada Acharya, Lei Yu, Tongyun Liu, et al.. Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. Journal of Virology, American Society for Microbiology, 2015, 89 (17), pp.8840-8854. ⟨10.1128/JVI.01232-15⟩. ⟨hal-02530901⟩
  • Carlos Moscoso, Li Xing, Jinwen Hui, Jeffrey Hu, Mohammad Baikoghli Kalkhoran, et al.. Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops. Scientific Reports, Nature Publishing Group, 2015, 4 (1), ⟨10.1038/srep07025⟩. ⟨cea-02530807⟩
  • Kawthar Bouchemal, Armelle Aka-Any-Grah, Nathalie Dereuddre-Bosquet, Loïc Martin, Vanessa Lievin-Le-Moal, et al.. Thermosensitive and Mucoadhesive Pluronic-Hydroxypropylmethylcellulose Hydrogel Containing the Mini-CD4 M48U1 Is a Promising Efficient Barrier against HIV Diffusion through Macaque Cervicovaginal Mucus. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, 59 (4), pp.2215-2222. ⟨10.1128/AAC.03503-14⟩. ⟨cea-02530843⟩
  • Jonathan Richard, Maxime Veillette, Nathalie Brassard, Shilpa Iyer, Michel Roger, et al.. CD4 mimetics sensitize HIV-1-infected cells to ADCC. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2015, 112 (20), pp.E2687-E2694. ⟨10.1073/pnas.1506755112⟩. ⟨hal-02530884⟩
  • Hannah Barbian, Julie Decker, Frederic Bibollet-Ruche, Rachel Galimidi, Anthony West, et al.. Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas. mBio, American Society for Microbiology, 2015, 6 (2), ⟨10.1128/mBio.00296-15⟩. ⟨cea-02530869⟩
  • P. Acharya, W. Tolbert, N. Gohain, X. Wu, Linwen Yu, et al.. Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. Journal of Virology, American Society for Microbiology, 2014, 88 (21), pp.12895-12906. ⟨10.1128/JVI.02194-14⟩. ⟨cea-02530781⟩
  • Carolina Herrera, Natalia Olejniczak, Javier García Pérez, Jose Alcami, Loïc Martin, et al.. Combinations of Entry and Reverse Transcriptase Inhibitors as Candidate Microbicides. AIDS Research and Human Retroviruses, Mary Ann Liebert, 2014, 30 (S1), pp.A213-A213. ⟨10.1089/aid.2014.5461.abstract⟩. ⟨hal-02542966⟩
  • Priyamvada Acharya, Timothy Luongo, Mark k. Louder, Krisha Mckee, Yongping Yang, et al.. Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1. Structure, Elsevier (Cell Press), 2013, 21 (6), pp.1018-1029. ⟨10.1016/j.str.2013.04.015⟩. ⟨hal-02530653⟩
  • Philippe Selhorst, Katrijn Grupping, Tommy Tong, Ema Crooks, Loïc Martin, et al.. M48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding. Retrovirology, BioMed Central, 2013, 10 (1), pp.12. ⟨10.1186/1742-4690-10-12⟩. ⟨hal-02542962⟩
  • P. Acharya, T. Luongo, I. Georgiev, J. Matz, S. Schmidt, et al.. Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites. Journal of Virology, American Society for Microbiology, 2013, 87 (18), pp.10173-10181. ⟨10.1128/JVI.01332-13⟩. ⟨hal-02530765⟩
  • Laurence Morellato-Castillo, Priyamvada Acharya, Olivier Combes, Johan Michiels, Anne Descours, et al.. Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein. Journal of Medicinal Chemistry, American Chemical Society, 2013, 56 (12), pp.5033-5047. ⟨10.1021/jm4002988⟩. ⟨hal-02530667⟩
  • Kawthar Bouchemal, Justyna Frelichowska, Loïc Martin, Vanessa Liévin-Le Moal, Roger Le Grand, et al.. Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide. International Journal of Pharmaceutics, Elsevier, 2013, 454 (2), pp.649-652. ⟨10.1016/j.ijpharm.2013.02.055⟩. ⟨hal-02530642⟩
  • J. Matz, P. Kessler, J. Bouchet, O. Combes, O. Ramos, et al.. Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120. Journal of Virology, American Society for Microbiology, 2012, 87 (2), pp.1137-1149. ⟨10.1128/JVI.00461-12⟩. ⟨cea-02530610⟩
  • Katrijn Grupping, Philippe Selhorst, Johan Michiels, Katleen Vereecken, Leo Heyndrickx, et al.. MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency. Retrovirology, BioMed Central, 2012, 9 (1), pp.36. ⟨10.1186/1742-4690-9-36⟩. ⟨cea-02530546⟩
  • Antu Dey, Brian Burke, Yide Sun, Klara Sirokman, Avishek Nandi, et al.. Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein. PLoS ONE, Public Library of Science, 2012, 7 (1), pp.e30233. ⟨10.1371/journal.pone.0030233⟩. ⟨cea-02530537⟩
  • N. Suffee, H. Hlawaty, A. Meddahi-Pelle, L. Maillard, L. Louedec, et al.. RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans. Angiogenesis, Springer Verlag, 2012, 15 (4), pp.727-744. ⟨10.1007/s10456-012-9285-x⟩. ⟨cea-02530559⟩
  • Julie Matz, Pacal Kessler, Jérome Bouchet, Olivier Combes, Daniel Baty, et al.. Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120. Retrovirology, BioMed Central, 2012, 9 (Suppl 2), pp.P214. ⟨inserm-00731772⟩
  • Priyamvada Acharya, Timothy Luongo, Julie Matz, Stephen Schmidt, Gwo-Yu Chuang, et al.. Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization. Retrovirology, BioMed Central, 2012, 9 (Suppl 2), pp.P346. ⟨inserm-00731776⟩
  • Nathalie Dereuddre-Bosquet, Laurence Morellato-Castillo, Joachim Brouwers, Patrick Augustijns, Kawthar Bouchemal, et al.. MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques. PLoS Pathogens, Public Library of Science, 2012, 8 (12), pp.e1003071. ⟨10.1371/journal.ppat.1003071⟩. ⟨cea-02530573⟩
  • C. Moscoso, Y. Sun, S. Poon, L. Xing, E. Kan, et al.. Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2011, 108 (15), pp.6091-6096. ⟨10.1073/pnas.1016113108⟩. ⟨cea-02530515⟩
  • Priyamvada Acharya, Cajetan Dogo-Isonagie, Judith Lalonde, Son Lam, George Leslie, et al.. Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry. ACS Chemical Biology, American Chemical Society, 2011, 6 (10), pp.1069-1077. ⟨10.1021/cb200068b⟩. ⟨cea-02530519⟩
  • Grégoire Martin, Brian Burke, Robert Thai, Antu Dey, Olivier Combes, et al.. Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (24), pp.21706-21716. ⟨cea-01989703⟩
  • Maylis Dagouassat, Nadine Suffee, Hanna Hlawaty, Oualid Haddad, Faten Charni, et al.. Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. International Journal of Cancer, Wiley, 2010, 126 (5), pp.1095-1108. ⟨10.1002/ijc.24800⟩. ⟨cea-02529147⟩
  • K Grupping, L. Heyndrickx, J. Michiels, G. Martin, Loïc Martin, et al.. Resistance to the CD4 mimetic mini protein M48-U1 induces changes in a highly conserved region on the HIV-1 gp120 envelope protein. Retrovirology, BioMed Central, 2009, 6 (S3-P12-11), ⟨10.1186/1742-4690-6-S3-P177⟩. ⟨hal-02542981⟩
  • Cg Moscoso, E Kan, S Poon, Y. Sun, Loïc Martin, et al.. P19-23. Putative prefusion mechanism of HIV-1 Env revealed by ligand-induced quaternary alterations in o-gp140 trimers. Retrovirology, BioMed Central, 2009, 6 (Suppl 3), pp.P343. ⟨10.1186/1742-4690-6-S3-P343⟩. ⟨hal-02542974⟩
  • Virginie Ropars, Philippe Barthe, Chi-Shien Wang, Wenlung Chen, Der-Lii Tzou, et al.. Structural Studies of the Complex Between Akt-in and the Akt2-PH Domain Suggest that the Peptide Acts as an Allosteric Inhibitor of the Akt Kinase. The Open Spectroscopy Journal, 2009, 3 (1), pp.65-76. ⟨10.2174/1874383800903010065⟩. ⟨hal-02543033⟩
  • Faten Charni, Véronique Friand, Oualid Haddad, Hanna Hlawaty, Loïc Martin, et al.. Syndecan-1 and syndecan-4 are involved in RANTES/CCL5-induced migration and invasion of human hepatoma cells. Biochimica et Biophysica Acta (BBA) - General Subjects, Elsevier, 2009, 1790 (10), pp.1314-1326. ⟨10.1016/j.bbagen.2009.07.015⟩. ⟨cea-02529135⟩
  • Rebecca L. Rich, Giuseppe A. Papalia, Peter J. Flynn, Jamie Furneisen, John Quinn, et al.. A global benchmark study using affinity-based biosensors. Analytical Biochemistry, Elsevier Masson, 2009, 386 (2), pp.194-216. ⟨10.1016/j.ab.2008.11.021⟩. ⟨hal-01527917⟩
  • François Stricher, Chih-Chin Huang, Anne Descours, Sophie Duquesnoy, Olivier Combes, et al.. Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein. Journal of Molecular Biology, Elsevier, 2008, 382 (2), pp.510-524. ⟨10.1016/j.jmb.2008.06.069⟩. ⟨hal-02528576⟩
  • Grégoire Martin, Yide Sun, Bernadette Heyd, Olivier Combes, Jeffrey Ulmer, et al.. A simple one-step method for the preparation of HIV-1 envelope glycoprotein immunogens based on a CD4 mimic peptide. Virology, Elsevier, 2008, 381 (2), pp.241-250. ⟨10.1016/j.virol.2008.08.039⟩. ⟨hal-02528592⟩
  • Angela Sutton, Veronique Friand, Dulce Papy-Garcia, Maylis Dagouassat, Loïc Martin, et al.. Glycosaminoglycans and their synthetic mimetics inhibit RANTES-induced migration and invasion of human hepatoma cells.. Molecular Cancer Therapeutics, American Association for Cancer Research, 2007, 6 (11), pp.2948-58. ⟨10.1158/1535-7163.MCT-07-0114⟩. ⟨hal-00195453⟩
  • François Stricher, Loïc Martin, Philippe Barthe, Vivian Pogenberg, Alain Mechulam, et al.. A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic. Biochemical Journal, Portland Press, 2005, 390 (1), pp.29-39. ⟨10.1042/BJ20041953⟩. ⟨hal-02528566⟩
  • Chih-Chin Huang, François Stricher, Loïc Martin, Julie Decker, Shahzad Majeed, et al.. Scorpion-Toxin Mimics of CD4 in Complex with Human Immunodeficiency Virus gp120: Crystal Structures,Molecular Mimicry, and Neutralization Breadth. Structure, Elsevier (Cell Press), 2005, 13 (5), pp.755-768. ⟨10.1016/j.str.2005.03.006⟩. ⟨hal-02528561⟩
  • Ramalakshmi Darbha, Sanjay Phogat, Aran Labrijn, Yuuei Shu, Yijun Gu, et al.. Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope † , ‡. Biochemistry, American Chemical Society, 2004, 43 (6), pp.1410-1417. ⟨10.1021/bi035323x⟩. ⟨hal-02543015⟩
  • Loïc Martin, François Stricher, Dorothée Missé, Francesca Sironi, Martine Pugnière, et al.. Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes. Nature Biotechnology, Nature Publishing Group, 2003, 21 (1), pp.71-76. ⟨10.1038/nbt768⟩. ⟨hal-02528557⟩
  • Enrico A Stura, Loïc Martin, Hugues Lortat-Jacob, Romain R Vivès, Claudio Vita. Heparin-aggregated RANTES can be crystallised.. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2002, 58 (Pt 10 Pt 1), pp.1670-3. ⟨hal-01061424⟩
  • Qi Zhu, Songping Liang, Loïc Martin, Sylvaine Gasparini, André Ménez, et al.. Role of Disulfide Bonds in Folding and Activity of Leiurotoxin I: Just Two Disulfides Suffice. Biochemistry, American Chemical Society, 2002, 41 (38), pp.11488-11494. ⟨10.1021/bi026136m⟩. ⟨hal-02528546⟩
  • Claudio Vita, Eugenia Drakopoulou, Loyda Ylisastigui, Youssef Bakri, Jean Vizzavona, et al.. Synthesis and characterization of biologically functional biotinylated RANTES. Journal of Immunological Methods, Elsevier, 2002, 266 (1-2), pp.53-65. ⟨10.1016/s0022-1759(02)00096-0⟩. ⟨hal-02528550⟩
  • Loïc Martin, C. Vita, A. Ivancich, F. Formaggio, C. Toniolo. Solid-phase synthesis of peptides containing the spin-labeled 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid (TOAC). Journal of Peptide Research, Wiley-Blackwell, 2001, 58 (5), pp.424-432. ⟨10.1034/j.1399-3011.2001.00940.x⟩. ⟨hal-02543003⟩
  • Loïc Martin, Cédric Blanpain, Pascale Garnier, Valérie Wittamer, Marc Parmentier, et al.. Structural and Functional Analysis of the RANTES-Glycosaminoglycans Interactions. Biochemistry, American Chemical Society, 2001, 40 (21), pp.6303-6318. ⟨10.1021/bi002670n⟩. ⟨hal-02528544⟩
  • Loïc Martin, Claudio Vita. Engineering Novel Bioactive Mini-Proteins from Small Size Natural and De Novo Designed Scaffolds. Current Protein & Peptide Science, Bentham Science, 2000, 1 (4), pp.403-430. ⟨10.2174/1389203003381306⟩. ⟨hal-02543052⟩
  • Loïc Martin, Philipe Barthe, Olivier Combes, Christian Roumestand, Claudio Vita. Engineering Novel Bioactive Mini-Proteins on Natural Scaffolds. Tetrahedron, Elsevier, 2000, 56 (48), pp.9451-9460. ⟨10.1016/S0040-4020(00)00829-2⟩. ⟨hal-02528540⟩
  • Loïc Martin, Fabrice Cornille, Serge Turcaud, Hervé Meudal, Bernard Roques, et al.. Metallopeptidase Inhibitors of Tetanus Toxin: A Combinatorial Approach. Journal of Medicinal Chemistry, American Chemical Society, 1999, 42 (3), pp.515-525. ⟨10.1021/jm981066w⟩. ⟨hal-02528535⟩
  • Loïc Martin, Fabrice Cornille, Pascale Coric, Bernard Roques, Marie-Claude Fournie-Zaluski. β-Amino-thiols Inhibit the Zinc Metallopeptidase Activity of Tetanus Toxin Light Chain. Journal of Medicinal Chemistry, American Chemical Society, 1998, 41 (18), pp.3450-3460. ⟨10.1021/jm981015z⟩. ⟨hal-02461413⟩
  • Laurent Bischoff, Christelle David, Loïc Martin, Hervé Meudal, Bernard-Pierre Roques, et al.. 2,4-Dinitrophenyl 4-Methoxybenzyl Disulfide: A New Efficient Reagent for the Electrophilic Sulfenylation of β-Amino Ester Enolates. Journal of Organic Chemistry, American Chemical Society, 1997, 62 (14), pp.4848-4850. ⟨10.1021/jo9623853⟩. ⟨hal-02122111⟩
  • Fabrice Cornille, Loïc Martin, Christine Lenoir, Didier Cussac, Bernard Roques, et al.. Allosteric-type control of synaptobrevin cleavage by tetanus toxin light chain. Letters in Peptide Science, Springer Verlag, 1997, 4 (4-6), pp.207-212. ⟨10.1007/BF02442877⟩. ⟨hal-02528513⟩
  • Fabrice Cornille, Loïc Martin, Christine Lenoir, Didier Cussac, Bernard Roques, et al.. Cooperative Exosite-dependent Cleavage of Synaptobrevin by Tetanus Toxin Light Chain. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1997, 272 (6), pp.3459-3464. ⟨10.1074/jbc.272.6.3459⟩. ⟨hal-02528515⟩
  • Jean-Marc Soleilhac, Fabrice Cornille, Loïc Martin, Christine Lenoir, Marie-Claude Fournié-Zaluski, et al.. A Sensitive and Rapid Fluorescence-Based Assay for Determination of Tetanus Toxin Peptidase Activity. Analytical Biochemistry, Elsevier Masson, 1996, 241 (1), pp.120-127. ⟨10.1006/abio.1996.0385⟩. ⟨hal-02528509⟩

Book sections1 document

  • François Stricher, Loïc Martin, Claudio Vita. Design of Miniproteins by the Transfer of Active Sites Onto Small-Size Scaffolds. Protein Design, 340, Humana Press, pp.113-150, 2006, Part of the Methods in Molecular Biology book series (MIMB, volume 340), ⟨10.1385/1-59745-116-9:113⟩. ⟨hal-02528572⟩