Loic Hamon

Documents

Publications

	RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation Clément Demongin , Samuel Tranier , Vandana Joshi , Léa Ceschi , Bénédicte Desforges Journal of Biological Chemistry, 2024, pp.105716. ⟨10.1016/j.jbc.2024.105716⟩ Article dans une revue hal-04455540v1
	FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage Evgeniya Mamontova , Marie-Jeanne Clément , Maria Sukhanova , Vandana Joshi , Ahmed Bouhss Cell Reports, 2023, 42 (10), pp.113199. ⟨10.1016/j.celrep.2023.113199⟩ Article dans une revue hal-04231448v1
	FUS fibrillation occurs through a nucleation-based process below the critical concentration required for liquid–liquid phase separation Emilie Bertrand , Clément Demongin , Ioana Dobra , Juan-Carlos Rengifo-Gonzalez , Anastasia S Singatulina Scientific Reports, 2023, 13 (1), pp.7772. ⟨10.1038/s41598-023-34558-1⟩ Article dans une revue hal-04231423v1
	YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells Karina Budkina , Krystel El Hage , Marie-Jeanne Clément , Bénédicte Desforges , Ahmed Bouhss Nucleic Acids Research, 2021, 49 (17), pp.10061-10081. ⟨10.1093/nar/gkab748⟩ Article dans une revue hal-03333572v1
	ITSN1 regulates SAM68 solubility through SH3 domain interactions with SAM68 proline-rich motifs S. Pankivskyi , D. Pastré , E. Steiner , V. Joshi , A. Rynditch Cellular and Molecular Life Sciences, 2021, 78, pp.1745-1763. ⟨10.1007/s00018-020-03610-y⟩ Article dans une revue hal-02968869v1
	Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain Anastasiia Samsonova , Krystel El Hage , Bénédicte Desforges , Vandana Joshi , Marie-Jeanne Clément Communications Biology, 2021, 4 (1), pp.359. ⟨10.1038/s42003-021-01862-3⟩ Article dans une revue hal-03176308v1
	Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1 Konstantin Naumenko , Mariya Sukhanova , Loic Hamon , Tatyana Kurgina , Elizaveta Alemasova Biomolecules, 2020, 10 (9), pp.1325. ⟨10.3390/biom10091325⟩ Article dans une revue hal-02968966v1
	Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus Dmitry Kretov , Daria Mordovkina , Irina Eliseeva , Dmitry Lyabin , Dmitry Polyakov Cells, 2020, 9 (1), pp.104. ⟨10.3390/cells9010104⟩ Article dans une revue hal-02968925v1
	PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA Anastasia Singatulina , Loic Hamon , Maria Sukhanova , Bénédicte Desforges , Vandana Joshi Cell Reports, 2019, 27 (6), pp.1809-1821. ⟨10.1016/j.celrep.2019.04.031⟩ Article dans une revue hal-02167709v1
	A Single-Molecule Atomic Force Microscopy Study of PARP1 and PARP2 Recognition of Base Excision Repair DNA Intermediates Maria Sukhanova , Loic Hamon , Mikhail Kutuzov , Vandana Joshi , Sanae Abrakhi Journal of Molecular Biology, 2019, 431 (15), pp.2655-2673. ⟨10.1016/j.jmb.2019.05.028⟩ Article dans une revue hal-02165889v1
	YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis Dmitry Kretov , Marie-Jeanne Clément , Guillaume Lambert , Dominique Durand , Dmitry Lyabin Nucleic Acids Research, 2019, 47 (6), pp.3127-3141. ⟨10.1093/nar/gky1303⟩ Article dans une revue hal-02114790v1
	Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases Ioana Dobra , Serhii Pankivskyi , Anastasiia Samsonova , David Pastre , Loic Hamon Current Neurology and Neuroscience Reports, 2018, 18 (12), pp.107. ⟨10.1007/s11910-018-0914-7⟩ Article dans une revue hal-02167725v1
	Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins Alexandre Maucuer , Bénédicte Desforges , Vandana Joshi , Mirela Boca , Dmitry Kretov Journal of Cell Science, 2018, 131 (11), pp.jcs214692. ⟨10.1242/jcs.214692⟩ Article dans une revue hal-02166855v1
	Nanoscale Analysis Reveals the Maturation of Neurodegeneration-Associated Protein Aggregates Sanae Abrakhi , Dmitry Kretov , Bénédicte Desforges , Ioana Dobra , Ahmed Bouhss ACS Nano, 2017, 11 (7), pp.7189-7200. ⟨10.1021/acsnano.7b03071⟩ Article dans une revue hal-02173623v1
	Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles Louic Vermeer , Loic Hamon , Alicia Schirer , Michel Schoup , Jérémie Cosette Acta Biomaterialia, 2017, 64, pp.259-268. ⟨10.1016/j.actbio.2017.10.009⟩ Article dans une revue hal-02174366v1
	Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging Maria Sukhanova , Sanae Abrakhi , Vandana Joshi , David Pastre , Mikhail Kutuzov Nucleic Acids Research, 2016, 44 (6), pp.e60-e60. ⟨10.1093/nar/gkv1476⟩ Article dans une revue hal-02183571v1
	Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding Alix Méphon-Gaspard , Mirela Boca , Catherine Pioche-Durieu , Bénédicte Desforges , Andrea Burgo Cellular and Molecular Life Sciences, 2016, 73 (19), pp.3745-3760. ⟨10.1007/s00018-016-2216-z⟩ Article dans une revue hal-02183396v1
	Polyamine signal through gap junctions : A key regulator of proliferation and gap-junction organization in mammalian tissues ? Loic Hamon , Philippe Savarin , David Pastre BioEssays, 2016, 38 (6), pp.498-507. ⟨10.1002/bies.201500195⟩ Article dans une revue hal-02174559v1
	mRNA and DNA selection via protein multimerization: YB-1 as a case study Dmitry Kretov , Patrick A. Curmi , Loic Hamon , Sanae Abrakhi , Bénédicte Desforges Nucleic Acids Research, 2015, 43 (19), pp.9457-9473. ⟨10.1093/nar/gkv822⟩ Article dans une revue hal-02183823v1
	Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules Ouissame Bounedjah , Bénédicte Desforges , Ting-Di Wu , Catherine Pioche-Durieu , Sergio Marco Nucleic Acids Research, 2014, 42 (13), pp.8678-8691. ⟨10.1093/nar/gku582⟩ Article dans une revue hal-02292175v1
	Structural Basis for the Association of MAP6 Protein with Microtubules and Its Regulation by Calmodulin Julien Lefèvre , Philippe Savarin , Pierre Gans , Loïc Hamon , Marie-Jeanne Clément Journal of Biological Chemistry, 2013, 288 (34), pp.24910-24922. ⟨10.1074/jbc.M113.457267⟩ Article dans une revue inserm-00858655v1
	An intercellular polyamine transfer via gap junctions regulates proliferation and response to stress in epithelial cells Bénédicte Desforges , Patrick Curmi , Ouissame Bounedjah , Samir Nakib , Loic Hamon Molecular Biology of the Cell, 2013, 24 (10), pp.1505-1613. ⟨10.1091/mbc.E12-10-0729⟩ Article dans une revue hal-02292186v1
	Detection of Single DNA Molecule Hybridization on a Surface by Atomic Force Microscopy David Pastre , Vandana Joshi , Patrick Curmi , Loic Hamon Small, 2013, 9 (21), pp.3630-3638. ⟨10.1002/smll.201300546⟩ Article dans une revue hal-02291850v1
	Macromolecular Crowding Regulates Assembly of mRNA Stress Granules after Osmotic Stress Ouissame Bounedjah , Loic Hamon , Philippe Savarin , Bénédicte Desforges , Patrick Curmi Journal of Biological Chemistry, 2012, 287 (4), pp.2446-2458. ⟨10.1074/jbc.M111.292748⟩ Article dans une revue hal-02292253v1
	Effect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1 Pavel Pestryakov , Dmitry Zharkov , Inga Grin , Elizaveta Fomina , Ekaterina Kim Journal of Molecular Recognition, 2012, 25 (4), pp.224-233. ⟨10.1002/jmr.2182⟩ Article dans une revue hal-02292246v1
	Rapid Assembly and Collective Behavior of Microtubule Bundles in the Presence of Polyamines Loic Hamon , Philippe Savarin , Patrick a. Curmi , David Pastre Biophysical Journal, 2011, 101 (1), pp.205-216. ⟨10.1016/j.bpj.2011.05.022⟩ Article dans une revue hal-02292262v1
	Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity Bénédicte Desforges , Philippe Savarin , Ouissame Bounedjah , Stephanie Delga , Loic Hamon American Journal of Physiology - Cell Physiology, 2011, 301 (3), pp.C705-C716. ⟨10.1152/ajpcell.00128.2011⟩ Article dans une revue hal-02292290v1
	Specific DNA−Protein Interactions on Mica Investigated by Atomic Force Microscopy David Pastré , Loic Hamon , Isabelle Sorel , Eric Le Cam , Patrick Curmi Langmuir, 2010, 26 (4), pp.2618-2623. ⟨10.1021/la902727b⟩ Article dans une revue hal-02293295v1
	A Central Role for Polyamines in Microtubule Assembly in Cells Philippe Savarin , Aurélie Barbet , Stephanie Delga , Vandana Joshi , Loic Hamon Biochemical Journal, 2010, 430 (1), pp.151-159. ⟨10.1042/BJ20091811⟩ Article dans une revue hal-00506521v1
	The Stathmin-Derived I19L Peptide Interacts with FtsZ and Alters Its Bundling Marie-Jeanne Clément , Boï-Trinh Kuoch , Tâp Ha-Duong , Vandana Joshi , Loic Hamon Biochemistry, 2009, 48 (41), pp.9734-9744. ⟨10.1021/bi900556a⟩ Article dans une revue hal-02295213v1
	Role of Microtubules in Stress Granule Assembly Konstantin G. Chernov , Aurélie Barbet , Loic Hamon , Lev Ovchinnikov , Patrick Curmi Journal of Biological Chemistry, 2009, 284 (52), pp.36569-36580. ⟨10.1074/jbc.M109.042879⟩ Article dans une revue hal-02295275v1
	Mica Surface Promotes the Assembly of Cytoskeletal Proteins Loic Hamon , Dulal Panda , Philippe Savarin , Vandana Joshi , Johann Bernhard Langmuir, 2009, 25 (6), pp.3331-3335. ⟨10.1021/la8035743⟩ Article dans une revue hal-02294800v1
	Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion Alain Mechulam , Konstantin G. Chernov , Elodie Mucher , Loic Hamon , Patrick A. Curmi PLoS Computational Biology, 2009, 5 (1), pp.e1000255. ⟨10.1371/journal.pcbi.1000255⟩ Article dans une revue inserm-00705780v1
	Atomic force microscopy reveals binding of mRNA to microtubules mediated by two major mRNP proteins YB-1 and PABP Konstantin G. Chernov , Patrick Curmi , Loic Hamon , Alain Mechulam , Lev Ovchinnikov FEBS Letters, 2008, 582 (19), pp.2875-2881. ⟨10.1016/j.febslet.2008.07.019⟩ Article dans une revue hal-02295333v1
	Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions David Pastre , Loic Hamon , Alain Mechulam , Isabelle Sorel , Sonia Baconnais Biomacromolecules, 2007, 8 (12), pp.3712-3717. ⟨10.1021/bm700856u⟩ Article dans une revue hal-02295397v1
	High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes L. Hamon , D. Pastré , P. Dupaigne , C. Breton , E. Cam Nucleic Acids Research, 2007, 35 (8), pp.e58-e58. ⟨10.1093/nar/gkm147⟩ Article dans une revue hal-02295472v1
	The EcoRI−DNA Complex as a Model for Investigating Protein−DNA Interactions by Atomic Force Microscopy Isabelle Sorel , Olivier Piétrement , Loic Hamon , Sonia Baconnais , Eric Le Cam Biochemistry, 2006, 45 (49), pp.14675-14682. ⟨10.1021/bi060293u⟩ Article dans une revue hal-03065288v1
	A new approach to DNA bending by polyamines and its implication in DNA condensation David Pastre , Olivier Piétrement , Fabrice Landousy , Loic Hamon , Isabelle Sorel European Biophysics Journal, 2006, 35 (3), pp.214-223. ⟨10.1007/s00249-005-0025-7⟩ Article dans une revue hal-03065301v1
	Anionic Polyelectrolyte Adsorption on Mica Mediated by Multivalent Cations: A Solution to DNA Imaging by Atomic Force Microscopy under High Ionic Strengths David Pastre , Loic Hamon , Fabrice Landousy , Isabelle Sorel , Marie-Odile David Langmuir, 2006, 22 (15), pp.6651-6660. ⟨10.1021/la053387y⟩ Article dans une revue hal-03065293v1
	Studying the effect of a charged surface on the interaction of bleomycin with DNA using an atomic force microscope Olivier Piétrement , David Pastre , Fabrice Landousy , Marie-Odile David , Stéphane Fusil European Biophysics Journal, 2005, 34 (3), pp.200-207. ⟨10.1007/s00249-004-0443-y⟩ Article dans une revue hal-03065310v1
	Thickness dependence of the glass transition temperature in thin films of partially miscible polymer blends. L. Hamon , Y. Grohens , Y. Holl Langmuir, 2003, 19, pp.10399-10402 Article dans une revue hal-00188278v1
	Reversible Binding of DNA on NiCl 2 -Treated Mica by Varying the Ionic Strength Olivier Piétrement , David Pastre , Stéphane Fusil , Josette Jeusset , Marie-Odile David Langmuir, 2003, 19 (7), pp.2536-2539. ⟨10.1021/la026942u⟩ Article dans une revue hal-03065317v1
	Adsorption of DNA to Mica Mediated by Divalent Counterions: A Theoretical and Experimental Study David Pastre , Olivier Piétrement , Stéphane Fusil , Fabrice Landousy , Josette Jeusset Biophysical Journal, 2003, 85 (4), pp.2507-2518. ⟨10.1016/s0006-3495(03)74673-6⟩ Article dans une revue hal-03065312v1

Loic Hamon

Publications

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation

FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage

FUS fibrillation occurs through a nucleation-based process below the critical concentration required for liquid–liquid phase separation

YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

ITSN1 regulates SAM68 solubility through SH3 domain interactions with SAM68 proline-rich motifs

Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1

Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus

PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA

A Single-Molecule Atomic Force Microscopy Study of PARP1 and PARP2 Recognition of Base Excision Repair DNA Intermediates

YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases

Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins

Nanoscale Analysis Reveals the Maturation of Neurodegeneration-Associated Protein Aggregates

Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles

Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging

Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding

Polyamine signal through gap junctions : A key regulator of proliferation and gap-junction organization in mammalian tissues ?

mRNA and DNA selection via protein multimerization: YB-1 as a case study

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

Structural Basis for the Association of MAP6 Protein with Microtubules and Its Regulation by Calmodulin

An intercellular polyamine transfer via gap junctions regulates proliferation and response to stress in epithelial cells

Detection of Single DNA Molecule Hybridization on a Surface by Atomic Force Microscopy

Macromolecular Crowding Regulates Assembly of mRNA Stress Granules after Osmotic Stress

Effect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1

Rapid Assembly and Collective Behavior of Microtubule Bundles in the Presence of Polyamines

Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity

Specific DNA−Protein Interactions on Mica Investigated by Atomic Force Microscopy

A Central Role for Polyamines in Microtubule Assembly in Cells

The Stathmin-Derived I19L Peptide Interacts with FtsZ and Alters Its Bundling

Role of Microtubules in Stress Granule Assembly

Mica Surface Promotes the Assembly of Cytoskeletal Proteins

Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion

Atomic force microscopy reveals binding of mRNA to microtubules mediated by two major mRNP proteins YB-1 and PABP

Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions

High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes

The EcoRI−DNA Complex as a Model for Investigating Protein−DNA Interactions by Atomic Force Microscopy

A new approach to DNA bending by polyamines and its implication in DNA condensation

Anionic Polyelectrolyte Adsorption on Mica Mediated by Multivalent Cations: A Solution to DNA Imaging by Atomic Force Microscopy under High Ionic Strengths

Studying the effect of a charged surface on the interaction of bleomycin with DNA using an atomic force microscope

Thickness dependence of the glass transition temperature in thin films of partially miscible polymer blends.

Reversible Binding of DNA on NiCl 2 -Treated Mica by Varying the Ionic Strength

Adsorption of DNA to Mica Mediated by Divalent Counterions: A Theoretical and Experimental Study