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Lionel MOUREY – CURRICULUM VITAE – Nov. 2020

 Lionel MOUREY – CURRICULUM VITAE – Nov. 2020

 

Family name: MOUREY           

Given name: Lionel

Nationality: French

Date of birth: 5 August 1961     

Place of birth: Vesoul, France

Marital status: Married, 2 children

Current position: CNRS senior researcher (DR1) – Institut de Pharmacologie et de Biologie Structurale (IPBS), CNRS – Université Toulouse 3

Address: IPBS, 205 route de Narbonne, BP 64182, 31077 Toulouse, France

Tel: (33) 5 61 17 54 36, Fax: (33) 5 61 17 59 94

Email: Lionel.Mourey@ipbs.fr

EDUCATION

- 2002:Habilitation à Diriger des Recherches (HDR), University of Toulouse

- 1991:PhD from the University of Strasbourg, Dr. D. Moras, Institut de Biologie Moléculaire et Cellulaire (IBMC), Strasbourg, France-

- 1988:DEA (master’s degree) of biological crystallography, University of Strasbourg

-    1984–1987:Engineer diploma, Ecole Nationale Supérieure de Chimie, Strasbourg

PROFESSIONNAL APPOINTMENTS

-    2009–2014: Joint director of the Structural Biology and Biophysics department, IPBS, Toulouse

-    2006–2014:Scientific supervisor of the Integrated Screening Platform of Toulouse (PICT)

-    Since 2005: CNRS senior researcher

-    Since 2002:Head of the structural biophysics team and of the biophysics and macromolecular crystallographic facility, IPBS, Toulouse

-    1992–2001: CNRS researcher, Laboratory of Crystallography, Dr. J.-P. Samama, IPBS, Toulouse

-    1991–1992:Post-doctoral fellow of Dr. D. Moras, IBMC, Strasbourg

KEYWORDS

Biochemistry; biophysics; structural biology; biocrystallography; protein-ligand interactions; structure-based ligand screening and design.

SYNOPSIS

I am senior researcher at CNRS and head of the "Structural biophysics" team and of the biophysics and macromolecular crystallography facility at IPBS. I am cofounder of the Integrated Platform of Screening of Toulouse (PICT), a national facility on structural biology and ligand screening, IBiSA labelled platform, certified ISO 9001:2008 and NF X50-900. My main competence is in the field of biochemistry, biophysics and structural biology, including X-ray crystallography of biological macromolecules and their complexes. I have contributed to the publication of 82 original articles in international journals (h-index=39) and contributed to the determination of 103 structures deposited with the Protein Data Bank.

CITATION METRICS

Number of articles in Web of Science: 82; number of book chapters and proceedings: 11.

Citations Google Scholar (as of 12 November 2020)

All

Since 2015

Citations count

4921

1767

h-index(at least h articles cited h times)

39

25

i10-index (number of articles cited at least 10 times)

71

47

 

 

 

 

 

 

 

 

Journal articles87 documents

  • Minh Chau Nguyen, Olivier Saurel, Coralie Carivenc, Sabine Gavalda, Stéphane Saitta, et al.. Conformational flexibility of coenzyme A and its impact on the post‐translational modification of acyl carrier proteins by 4′‐phosphopantetheinyl transferases. FEBS Journal, Wiley, 2020, 287, pp.4729 - 4746. ⟨10.1111/febs.15273⟩. ⟨hal-02950584⟩
  • Anna Grabowska, Yoann Brison, Laurent Maveyraud, Sabine Gavalda, Alexandre Faille, et al.. Molecular basis for extender unit specificity of mycobacterial polyketide synthases. ACS Chemical Biology, American Chemical Society, In press. ⟨hal-03018677⟩
  • Jacques Augenstreich, Evert Haanappel, Fadel Sayes, Roxane Simeone, Valerie Guillet, et al.. Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors. Frontiers in Cellular and Infection Microbiology, Frontiers, 2020, 10, pp.420. ⟨10.3389/fcimb.2020.00420⟩. ⟨pasteur-02873531⟩
  • Laurent Maveyraud, Lionel Mourey. Protein X-ray Crystallography and Drug Discovery. Molecules, MDPI, 2020, 25 (5), pp.1030. ⟨10.3390/molecules25051030⟩. ⟨hal-02950589⟩
  • Luis Garcia-Alles, Katharina Root, Laurent Maveyraud, Nathalie Aubry, Eric Lesniewska, et al.. Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components. Plos One, 2019, ⟨10.1371/journal.pone.0223877⟩. ⟨hal-03020711⟩
  • Valerie Guillet, Patricia Bordes, Cécile Bon, Julien Marcoux, Virginie Gervais, et al.. Structural insights into chaperone addiction of toxin-antitoxin systems. Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-08747-4⟩. ⟨hal-02335509⟩
  • Alexandre Faille, Sabine Gavalda, Nawel Slama, Christian Lherbet, Laurent Maveyraud, et al.. Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. Journal of Molecular Biology, Elsevier, 2017, 429 (47), pp.1554 - 1569. ⟨10.1016/j.jmb.2017.03.026⟩. ⟨hal-03002100⟩
  • Cyprian Cukier, Audrey Tourdes, Dounia El-Mazouni, Valérie Guillet, Julian Nomme, et al.. NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex. Protein Science, Wiley, 2017, 26 (11), pp.2240-2248. ⟨10.1002/pro.3282⟩. ⟨hal-03011459⟩
  • Cyprian Cukier, Audrey Tourdes, Dounia El-Mazouni, Valérie Guillet, Julian Nomme, et al.. NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex. Protein Science, Wiley, 2017, 26, pp.2240 - 2248. ⟨10.1002/pro.3282⟩. ⟨hal-03002130⟩
  • Yoann Brison, Yannick Malbert, Georges Czaplicki, Lionel Mourey, Magali Remaud-Simeon, et al.. Structural Insights into the Carbohydrate Binding Ability of an α-(1→2) Branching Sucrase from Glycoside Hydrolase Family 70. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (14), pp.7527-7540. ⟨10.1074/jbc.M115.688796⟩. ⟨hal-03002155⟩
  • Nguyen-Hung Le, Virginie Molle, Nathalie Eynard, Mathieu Miras, Alexandre Stella, et al.. Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (43), pp.22793-22805. ⟨10.1074/jbc.M116.748053⟩. ⟨hal-03002139⟩
  • Patricia Bordes, Ambre Julie Sala, Sara Ayala, Pauline Texier, Nawel Slama, et al.. Chaperone addiction of toxin–antitoxin systems. Nature Communications, Nature Publishing Group, 2016, 7, pp.13339. ⟨10.1038/ncomms13339⟩. ⟨hal-03002198⟩
  • Valérie Guillet, Ségolène Galandrin, Laurent Maveyraud, Simon Ladevèze, Vincent Mariaule, et al.. Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (15), pp.7973-7989. ⟨10.1074/jbc.M115.712612⟩. ⟨hal-03002148⟩
  • Nguyen-Hung Le, Virginie Molle, Nathalie Eynard, Mathieu Miras, Alexandre Stella, et al.. Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (43), pp.22793-22805. ⟨10.1074/jbc.M116.748053⟩. ⟨hal-01604694⟩
  • Yoann Brison, Yannick Malbert, Georges Czaplicki, Lionel Mourey, Magali Remaud Simeon, et al.. Structural insights into the carbohydrate binding ability of an alpha-(1 -> 2) branching sucrase from glycoside hydrolase family 70. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (14), pp.7527-7540. ⟨10.1074/jbc.M115.688796⟩. ⟨hal-01886416⟩
  • Frédérique Sabourdy, Lionel Mourey, Emmanuelle Le Trionnaire, Nathalie Bednarek, Catherine Caillaud, et al.. Natural disease history and characterisation of SUMF1 molecular defects in ten unrelated patients with multiple sulfatase deficiency. Orphanet Journal of Rare Diseases, BioMed Central, 2015, 10, pp.31. ⟨10.1186/s13023-015-0244-7⟩. ⟨hal-03002953⟩
  • Aurélien Chollet, Lionel Mourey, Christian Lherbet, Alexandra Delbot, Sylviane Julien, et al.. Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach. Journal of Structural Biology, Elsevier, 2015, 190, pp.328 - 337. ⟨10.1016/j.jsb.2015.04.008⟩. ⟨hal-03002973⟩
  • Sylviane Julien, Patrick Tondl, Fabien Durand, Adilia Dagkessamanskaia, Herman van Tilbeurgh, et al.. Crystallographic studies of the structured core domain of Knr4 from Saccharomyces cerevisiae. Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd,, 2015, 71 (9), pp.1120 - 1124. ⟨10.1107/S2053230X15012522⟩. ⟨hal-01883404⟩
  • Sylviane Julien, Patrick Tondl, Fabien Durand, Adilia Dagkessamanskaia, Herman van Tilbeurgh, et al.. Crystallographic studies of the structured core domain of Knr4 fromSaccharomyces cerevisiae. Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd,, 2015, 71, pp.1120 - 1124. ⟨10.1107/s2053230x15012522⟩. ⟨hal-03002962⟩
  • Simon Ladevèze, Gianluca Cioci, Pierre Roblin, Lionel Mourey, Samuel Tranier, et al.. Structural bases for N-glycan processing by mannoside phosphorylase. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2015, 71 (6), pp.1335-1346. ⟨10.1107/S1399004715006604⟩. ⟨hal-03002960⟩
  • Simon Ladeveze, Gianluca Cioci, Pierre Roblin, Lionel Mourey, Samuel Tranier, et al.. Structural bases for N-glycan processing by mannoside phosphorylase. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2015, 71 (Part 6), pp.1335-46. ⟨10.1107/S1399004715006604⟩. ⟨hal-01183896⟩
  • Sabine Gavalda, Fabienne Bardou, Françoise Laval, Cécile Bon, Wladimir Malaga, et al.. The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria. Chemistry and Biology, Elsevier, 2014, 21 (12), pp.1660-1669. ⟨10.1016/j.chembiol.2014.10.011⟩. ⟨hal-02322376⟩
  • Béatrice Siguier, Mireille Haon, Virginie Nahoum, Marlène Marcellin, Odile Burlet-Schiltz, et al.. First Structural Insights into α-l-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (8), pp.5261-5273. ⟨10.1074/jbc.M113.528133⟩. ⟨hal-02419708⟩
  • Catherine Vilchèze, Virginie Molle, Severine Carrere-Kremer, Jade Leiba, Lionel Mourey, et al.. Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis. PLoS Pathogens, Public Library of Science, 2014, 10 (5), pp.e1004115. ⟨10.1371/journal.ppat.1004115⟩. ⟨hal-02282645⟩
  • Catherine Vilchèze, Virginie Molle, Séverine Carrère-Kremer, Jade Leiba, Lionel Mourey, et al.. Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis. PLoS Pathogens, Public Library of Science, 2014, 10 (5), pp.e1004115. ⟨10.1371/journal.ppat.1004115⟩. ⟨hal-03002975⟩
  • Benoit-Joseph Laventie, Frédéric Guerin, Lionel Mourey, Mira Tawk, Emmanuel Jover, et al.. Residues Essential for Panton-Valentine Leukocidin S Component Binding to Its Cell Receptor Suggest Both Plasticity and Adaptability in Its Interaction Surface. PLoS ONE, Public Library of Science, 2014, 9 (3), pp.e92094. ⟨10.1371/journal.pone.0092094⟩. ⟨hal-03002978⟩
  • Sabine Gavalda, Fabienne Bardou, Françoise Laval, Cécile Bon, Wladimir Malaga, et al.. The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria. Chemistry and Biology, Elsevier, 2014, 21, pp.1660 - 1669. ⟨10.1016/j.chembiol.2014.10.011⟩. ⟨hal-03002982⟩
  • Béatrice Siguier, Mireille Haon, Virginie Nahoum, Marlène Marcellin, Odile Burlet-Schiltz, et al.. First Structural Insights into α-l-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289, pp.5261 - 5273. ⟨10.1074/jbc.m113.528133⟩. ⟨hal-03002976⟩
  • Christina Gros, Laurence Fleury, Virginie Nahoum, Céline Faux, Sergio Valente, et al.. New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 290, pp.6293 - 6302. ⟨10.1074/jbc.m114.594671⟩. ⟨hal-03002969⟩
  • Karine Rottier, Alexandre Faille, Thomas Prudhomme, Cécile Leblanc, Christian Chalut, et al.. Detection of soluble co-factor dependent protein expression in vivo : Application to the 4′-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis. Journal of Structural Biology, Elsevier, 2013, 183 (3), pp.320 - 328. ⟨10.1016/j.jsb.2013.07.010⟩. ⟨hal-03002994⟩
  • Ségolène Galandrin, Valérie Guillet, Rajendra Rane, Mathieu Léger, N. Radha, et al.. Assay Development for Identifying Inhibitors of the Mycobacterial FadD32 Activity. Journal of Biomolecular Screening, SAGE Publications, 2013, 18 (5), pp.576-587. ⟨10.1177/1087057112474691⟩. ⟨hal-03003002⟩
  • Olivier Cala, Marie-Hélène Remy, Valérie Guillet, Andreas Merdes, Lionel Mourey, et al.. Virtual and Biophysical Screening Targeting the γ-Tubulin Complex – A New Target for the Inhibition of Microtubule Nucleation. PLoS ONE, Public Library of Science, 2013, 8 (5), pp.e63908. ⟨10.1371/journal.pone.0063908⟩. ⟨hal-03003005⟩
  • Frédéric Guerin, Claire Moulis, Sophie Barbe, Thu Hoai Tran, Sandrine Morel, et al.. Applying Pairwise Combinations of Amino Acid Mutations for Sorting Out Highly Efficient Glucosylation Tools for Chemo-Enzymatic Synthesis of Bacterial Oligosaccharides. Journal of the American Chemical Society, American Chemical Society, 2012, 134 (45), pp.18677 - 18688. ⟨10.1021/ja306845b⟩. ⟨hal-01268260⟩
  • Frédéric Guerin, Sophie Barbe, Sandra Serin, Gabrielle Veronese, David Guieysse, et al.. Structural Investigation of the Thermostability and Product Specificity of Amylosucrase from the Bacterium Deinococcus geothermalis. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (9), pp.6642 - 6654. ⟨10.1074/jbc.M111.322917⟩. ⟨hal-01268407⟩
  • Rosa Milagros Corrales, Virginie Molle, Jade Leiba, Lionel Mourey, Chantal de Chastellier, et al.. Phosphorylation of Mycobacterial PcaA Inhibits Mycolic Acid Cyclopropanation. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (31), pp.26187-26199. ⟨10.1074/jbc.M112.373209⟩. ⟨hal-02282667⟩
  • Yoann Brison, Tjaard Pijning, Yannick Malbert, Emeline Fabre, Lionel Mourey, et al.. Functional and Structural Characterization of alpha-(1 -> 2) Branching Sucrase Derived from DSR-E Glucansucrase. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (11), pp.7915 - 7924. ⟨10.1074/jbc.M111.305078⟩. ⟨hal-01268398⟩
  • Fabien Bergeret, Sabine Gavalda, Christian Chalut, Wladimir Malaga, Annaïk Quémard, et al.. Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287, pp.33675 - 33690. ⟨10.1074/jbc.m111.325639⟩. ⟨hal-03003064⟩
  • Rosa Corrales, Virginie Molle, Jade Leiba, Lionel Mourey, Chantal de Chastellier, et al.. Phosphorylation of Mycobacterial PcaA Inhibits Mycolic Acid Cyclopropanation. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287, pp.26187 - 26199. ⟨10.1074/jbc.m112.373209⟩. ⟨hal-03003056⟩
  • Elise Champion, Frédéric Guerin, Claire Moulis, Sophie Barbe, Thu Tran, et al.. Applying Pairwise Combinations of Amino Acid Mutations for Sorting Out Highly Efficient Glucosylation Tools for Chemo-Enzymatic Synthesis of Bacterial Oligosaccharides. Journal of the American Chemical Society, American Chemical Society, 2012, 134, pp.18677 - 18688. ⟨10.1021/ja306845b⟩. ⟨hal-03003058⟩
  • Romain Galy, Fabien Bergeret, Daniel Keller, Lionel Mourey, Gilles Prévost, et al.. Crystallization and preliminary crystallographic studies of both components of the staphylococcal LukE–LukD leukotoxin. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, 68, pp.663 - 667. ⟨10.1107/s1744309112014662⟩. ⟨hal-03003049⟩
  • Yoann Brison, Tjaard Pijning, Yannick Malbert, Émeline Fabre, Lionel Mourey, et al.. Functional and Structural Characterization of α-(1→2) Branching Sucrase Derived from DSR-E Glucansucrase. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287, pp.7915 - 7924. ⟨10.1074/jbc.m111.305078⟩. ⟨hal-03003060⟩
  • Jean-Denis Pedelacq, Hau Nguyen, Stephanie Cabantous, Brian Mark, Pawel Listwan, et al.. Experimental mapping of soluble protein domains using a hierarchical approach. Nucleic Acids Research, Oxford University Press, 2011, 39, pp.e125 - e125. ⟨10.1093/nar/gkr548⟩. ⟨hal-03003363⟩
  • Luis Garcia-Alles, Gaelle Giacometti, Cees Versluis, Laurent Maveyraud, Diane de Paepe, et al.. Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2011, 108, pp.13230 - 13235. ⟨10.1073/pnas.1105627108⟩. ⟨hal-03003375⟩
  • Justin Kollman, Andreas Merdes, Lionel Mourey, David Agard. Microtubule nucleation by γ-tubulin complexes. Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2011, 12, pp.709 - 721. ⟨10.1038/nrm3209⟩. ⟨hal-03003365⟩
  • Valérie Guillet, Martine Knibiehler, Lynn Gregory-Pauron, Marie-Hélène Remy, Cécile Chemin, et al.. Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation. Nature Structural and Molecular Biology, Nature Publishing Group, 2011, 18, pp.915 - 919. ⟨10.1038/nsmb.2083⟩. ⟨hal-03003370⟩
  • Frédéric Guerin, Sophie Barbe, Sandra Pizzut-Serin, Gabrielle Potocki-Veronese, David Guieysse, et al.. Structural Investigation of the Thermostability and Product Specificity of Amylosucrase from the BacteriumDeinococcus geothermalis. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 287, pp.6642 - 6654. ⟨10.1074/jbc.m111.322917⟩. ⟨hal-03003044⟩
  • Florence Bordes, Sophie Barbe, Pierre Escalier, Lionel Mourey, Isabelle André, et al.. Exploring the Conformational States and Rearrangements of Yarrowia lipolytica Lipase. Biophysical Journal, Biophysical Society, 2010, 99 (7), pp.2225 - 2234. ⟨10.1016/j.bpj.2010.07.040⟩. ⟨hal-02667777⟩
  • Florence Bordes, Sophie Barbe, Pierre Escalier, Lionel Mourey, Isabelle André, et al.. Exploring the Conformational States and Rearrangements of Yarrowia lipolytica Lipase. Biophysical Journal, Biophysical Society, 2010, 99, pp.2225 - 2234. ⟨10.1016/j.bpj.2010.07.040⟩. ⟨hal-03003379⟩
  • Julien Vaubourgeix, Fabienne Bardou, Fanny Boissier, Sylviane Julien, Patricia Constant, et al.. S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor ofMycobacterium tuberculosisMycolic Acid Methyltransferases. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284, pp.19321 - 19330. ⟨10.1074/jbc.m809599200⟩. ⟨hal-03003382⟩
  • Mathieu Léger, Sabine Gavalda, Valérie Guillet, Benoît van der Rest, Nawel Slama, et al.. The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis. Chemistry and Biology, Elsevier, 2009, 16, pp.510 - 519. ⟨10.1016/j.chembiol.2009.03.012⟩. ⟨hal-03003389⟩
  • Julie Guiard, Anthony Collmann, Luis Garcia-Alles, Lionel Mourey, Thérèse Brando, et al.. Fatty Acyl Structures of Mycobacterium tuberculosis Sulfoglycolipid Govern T Cell Response. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182, pp.7030 - 7037. ⟨10.4049/jimmunol.0804044⟩. ⟨hal-03003394⟩
  • Damien Bessière, Chrystelle Lacroix, Sébastien Campagne, Vincent Ecochard, Valérie Guillet, et al.. Structure-Function Analysis of the THAP Zinc Finger of THAP1, a Large C2CH DNA-binding Module Linked to Rb/E2F Pathways. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283, pp.4352 - 4363. ⟨10.1074/jbc.m707537200⟩. ⟨hal-03003405⟩
  • Pierre Roblin, Valérie Guillet, Olivier Joubert, Daniel Keller, Monique Erard, et al.. A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of β-barrel pore-forming toxins. Proteins - Structure, Function and Bioinformatics, Wiley, 2008, 71, pp.485 - 496. ⟨10.1002/prot.21900⟩. ⟨hal-03003397⟩
  • Laurent Maveyraud, Hideaki Niwa, Valérie Guillet, Dmitri Svergun, Peter Konarev, et al.. Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra. Proteins - Structure, Function and Bioinformatics, Wiley, 2008, 75, pp.89 - 103. ⟨10.1002/prot.22222⟩. ⟨hal-03003386⟩
  • Robert Alazard, Lionel Mourey, Christine Ebel, Peter Konarev, Maxim Petoukhov, et al.. Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets. Nucleic Acids Research, Oxford University Press, 2007, 35, pp.4420 - 4432. ⟨10.1093/nar/gkm453⟩. ⟨hal-03003424⟩
  • Olivier Joubert, Joëlle Voegelin, Valérie Guillet, Samuel Tranier, Sandra Werner, et al.. Distinction between Pore Assembly by Staphylococcal α-Toxin versus Leukotoxins. Journal of Biomedicine and Biotechnology, Hindawi Publishing Corporation, 2007, 2007, pp.025935. ⟨10.1155/2007/25935⟩. ⟨hal-03003420⟩
  • Olivier Joubert, Gabriella Viero, Daniel Keller, Eric Martinez, Didier A Colin, et al.. Engineered covalent leucotoxin heterodimers form functional pores: insights into S–F interactions. Biochemical Journal, Portland Press, 2006, 396 (2), pp.381-389. ⟨10.1042/BJ20051878⟩. ⟨hal-02337351⟩
  • Olivier Joubert, Gabriella Viero, Daniel Keller, Eric Martinez, Didier Colin, et al.. Engineered covalent leucotoxin heterodimers form functional pores: insights into S–F interactions. Biochemical Journal, Portland Press, 2006, 396, pp.381 - 389. ⟨10.1042/bj20051878⟩. ⟨hal-03003436⟩
  • Fanny Boissier, Fabienne Bardou, Valérie Guillet, Sandrine Uttenweiler-Joseph, Mamadou Daffé, et al.. Further Insight into S-Adenosylmethionine-dependent Methyltransferases: STRUCTURAL CHARACTERIZATION OF Hma, AN ENZYME ESSENTIAL FOR THE BIOSYNTHESIS OF OXYGENATED MYCOLIC ACIDS IN MYCOBACTERIUM TUBERCULOSIS. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (7), pp.4434-4445. ⟨10.1074/jbc.M510250200⟩. ⟨hal-03003456⟩
  • Luis Garcia-Alles, Kees Versluis, Laurent Maveyraud, Ana Tesouro Vallina, Sebastiano Sansano, et al.. Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. EMBO Journal, EMBO Press, 2006, 25, pp.3684 - 3692. ⟨10.1038/sj.emboj.7601244⟩. ⟨hal-03003440⟩
  • Henri de la Salle, Sabrina Mariotti, Catherine Angénieux, Martine Gilleron, Luis Fernando Garcia-Alles, et al.. Assistance of Microbial Glycolipid Antigen Processing by CD1e. Science, American Association for the Advancement of Science, 2005, 310 (5752), pp.1321-1324. ⟨10.1126/science.1115301⟩. ⟨hal-03003514⟩
  • Romain Veyron-Churlet, Olivier Guerrini, Lionel Mourey, Mamadou Daffé, Didier Zerbib. Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability. Molecular Microbiology, Wiley, 2004, 54 (5), pp.1161-1172. ⟨10.1111/j.1365-2958.2004.04334.x⟩. ⟨hal-03004144⟩
  • Valérie Guillet, Pierre Roblin, Sandra Werner, Manuela Coraiola, Gianfranco Menestrina, et al.. Crystal Structure of Leucotoxin S Component. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2004, 279, pp.41028 - 41037. ⟨10.1074/jbc.m406904200⟩. ⟨hal-03004162⟩
  • Sylvie Monferran, Catherine Muller, Lionel Mourey, Philippe Frit, Bernard Salles. The Membrane-associated Form of the DNA Repair Protein Ku is Involved in Cell Adhesion to Fibronectin. Journal of Molecular Biology, Elsevier, 2004, 337, pp.503 - 511. ⟨10.1016/j.jmb.2004.01.057⟩. ⟨hal-03004153⟩
  • Valérie Guillet, Daniel Keller, Gilles Prévost, Lionel Mourey. Crystallization and preliminary crystallographic data of a leucotoxin S component from Staphylococcus aureus. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2004, 60, pp.310 - 313. ⟨10.1107/s090744490302910x⟩. ⟨hal-03004171⟩
  • Marie Foussard, Stéphanie Cabantous, Jean-Denis Pedelacq, Valérie Guillet, Samuel Tranier, et al.. The molecular puzzle of two-component signaling cascades. Microbes and Infection, Elsevier, 2001, 3 (5), pp.417-424. ⟨10.1016/s1286-4579(01)01390-9⟩. ⟨hal-03004328⟩
  • Lionel Mourey, Sandra da Re, Jean-Denis Pedelacq, Tatiana Tolstykh, Cécile Faurie, et al.. Crystal Structure of the CheA Histidine Phosphotransfer Domain that Mediates Response Regulator Phosphorylation in Bacterial Chemotaxis. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276, pp.31074 - 31082. ⟨10.1074/jbc.m101943200⟩. ⟨hal-03004208⟩
  • Dasantila Golemi, Laurent Maveyraud, Akihiro Ishiwata, Samuel Tramer, Kazuyuki Miyashita, et al.. 6-(Hydroxyalkyl)penicillanates as Probes for Mechanisms of .BETA.-Lactamases.. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2000, 53 (10), pp.1022-1027. ⟨10.7164/antibiotics.53.1022⟩. ⟨hal-03004369⟩
  • Jean-Denis Pedelacq, Gilles Prevost, Henri Monteil, Lionel Mourey, Jean-Pierre Samama. Crystal structure of the F component of the Panton-Valentine leucocidin. Journal of Medical Microbiology, Society for General Microbiology, 2000, 290, pp.395 - 401. ⟨hal-03004342⟩
  • Catherine Birck, Lionel Mourey, Patrice Gouet, Béatrice Fabry, Jörg Schumacher, et al.. Conformational changes induced by phosphorylation of the FixJ receiver domain. Structure, Elsevier (Cell Press), 1999, 7 (12), pp.1505-1515. ⟨10.1016/s0969-2126(00)88341-0⟩. ⟨hal-03004414⟩
  • Lionel Mourey, Lakshmi Kotra, John Bellettiniʈ, Alexey Bulychev, Michael O'brienʈ, et al.. Inhibition of the Broad Spectrum Nonmetallocarbapenamase of Class A (NMC-A) ␤-Lactamase from Enterobacter cloacae by Monocyclic ␤-Lactams* □ S. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1999, 274, pp.25260 - 25265. ⟨hal-03004384⟩
  • Patrice Gouet, Béatrice Fabry, Valérie Guillet, Catherine Birck, Lionel Mourey, et al.. Structural transitions in the FixJ receiver domain. Structure, 1999. ⟨hal-03004398⟩
  • Jean-Denis Pedelacq, Laurent Maveyraud, Gilles Prévost, Lamine Baba-Moussa, Ana González, et al.. The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins. Structure, Elsevier (Cell Press), 1999, 7 (3), pp.277-287. ⟨10.1016/s0969-2126(99)80038-0⟩. ⟨hal-03004378⟩
  • Robert Alazard, Christine Ebel, Catherine Venien-Bryan, Lionel Mourey, Jean Samama, et al.. Oligomeric structure of the repressor of the bacteriophage Mu early operon. Eur J Biochem, 1998, 252 (3), pp.408 - 415. ⟨10.1046/j.1432-1327.1998.2520408.x⟩. ⟨hal-03004629⟩
  • Peter Swarén, Laurent Maveyraud, Xavier Raquet, Stéphanie Cabantous, Colette Duez, et al.. X-ray Analysis of the NMC-A β-Lactamase at 1.64-Å Resolution, a Class A Carbapenemase with Broad Substrate Specificity. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1998, 273 (41), pp.26714-26721. ⟨10.1074/jbc.273.41.26714⟩. ⟨hal-03004553⟩
  • Lionel Mourey, Kazuyuki Miyashita, Peter Swarén, Alexey Bulychev, Jean-Pierre Samama, et al.. Inhibition of the NMC-A β-Lactamase by a Penicillanic Acid Derivative and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme. Journal of the American Chemical Society, American Chemical Society, 1998, 120 (36), pp.9382-9383. ⟨10.1021/ja9817996⟩. ⟨hal-03004572⟩
  • Laurent Maveyraud, Lionel Mourey, Lakshmi Kotra, Jean-Denis Pedelacq, Valérie Guillet, et al.. Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A β-Lactamases from the Antibiotic-Resistant Bacteria. Journal of the American Chemical Society, American Chemical Society, 1998, 120 (38), pp.9748-9752. ⟨10.1021/ja9818001⟩. ⟨hal-03004592⟩
  • Lionel Mourey, Jean-Denis Pedelacq, Catherine Birck, Christine Fabre, Pierre Rougé, et al.. Crystal Structure of the Arcelin-1 Dimer from Phaseolus vulgaris at 1.9-Å Resolution. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1998, 273 (21), pp.12914-12922. ⟨10.1074/jbc.273.21.12914⟩. ⟨hal-03004563⟩
  • Martin Welch, Natalie Chinardet, Lionel Mourey, Catherine Birck, Jean-Pierre Samama. Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY. Nature Structural Biology, Nature Publishing Group, 1998, 5 (1), pp.25-29. ⟨10.1038/nsb0198-25⟩. ⟨hal-03004494⟩
  • Christine Fabre, Henri Causse, Lionel Mourey, Jos Koninkx, Michel Rivière, et al.. Characterization and sugar-binding properties of arcelin-1, an insecticidal lectin-like protein isolated from kidney bean (Phaseolus vulgaris L. cv. RAZ-2) seeds. Biochem. J, 1998, 329 (3), pp.551 - 560. ⟨10.1042/bj3290551⟩. ⟨hal-03004605⟩
  • Lionel Mourey, Jean-Denis Pedelacq, Christine Fabre, Henri Causse, Pierre Rougé, et al.. Small-Angle x-ray scattering and crystallographic studies of arcelin-1: An insecticidal lectin-like glycoprotein fromPhaseolus vulgaris L. Proteins: Structure, Function, and Genetics, Wiley, 1997, 29 (4), pp.433-442. ⟨10.1002/(sici)1097-0134(199712)29:4<433::aid-prot4>3.0.co;2-9⟩. ⟨hal-03004639⟩
  • Jean Cavarelli, Gilles Prévost, William Bourguet, Luc Moulinier, Bernard Chevrier, et al.. The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 Å resolution. Structure, Elsevier (Cell Press), 1997, 5 (6), pp.813-824. ⟨10.1016/s0969-2126(97)00235-9⟩. ⟨hal-03004650⟩
  • Laurent Maveyraud, Isabelle Saves, Odile Burlet-Schiltz, Peter Swarén, Jean-Michel Masson, et al.. Structural Basis of Extended Spectrum TEM ␤-Lactamases CRYSTALLOGRAPHIC, KINETIC, AND MASS SPECTROMETRIC INVESTIGATIONS OF ENZYME MUTANTS*. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1996, 271 (18), pp.10482-10489. ⟨10.1074/jbc.271.18.10482⟩. ⟨hal-03004742⟩
  • Peter Swarén, Laurent Maveyraud, Valérie Guillet, Jean-Michel Masson, Lionel Mourey, et al.. Electrostatic analysis of TEM1 -lactamase: effect of substrate binding, steep potential gradients and consequences of site-directed mutations. Structure, Elsevier (Cell Press), 1995, 3 (6), pp.603-613. ⟨10.1016/s0969-2126(01)00194-0⟩. ⟨hal-03004753⟩
  • Christian Jelsch, Lionel Mourey, Jean-Michel Masson, Jean-Pierre Samama. Crystal Structure of Escherichia coZi TEMl P-Lactamase at 1.8 A Resolution. Proteins: Structure, Function, and Genetics, Wiley, 1993, 16 (4), pp.16364 - 383. ⟨10.1002/prot.340160406⟩. ⟨hal-03004808⟩
  • Lionel Mourey, Jean-Pierre Samama, Marc Delarue, Maurice Petitou, Jean Choay, et al.. Crystal Structure of Cleaved Bovine Antithrombin III at 3·2 Å Resolution. Journal of Molecular Biology, Elsevier, 1993, 232 (1), pp.223-241. ⟨10.1006/jmbi.1993.1378⟩. ⟨hal-03004796⟩
  • Pierre Braunstein, Lionel Mourey, Jacky Rosé, Pierre Granger, Thierry Richert, et al.. Selectivity in substitution chemistry of mixed-metal, tetrahedral MCo3 (M = iron, ruthenium) carbonyl clusters: cobalt-59 NMR study and crystal structure of RuCo3(.mu.3-H)(.mu.-CO)3(CO)8(NMe3). Organometallics, American Chemical Society, 1992, 11 (7), pp.2628-2634. ⟨10.1021/om00043a054⟩. ⟨hal-03004821⟩

Book sections2 documents

  • Jean-Denis Pedelacq, Minh Chau Nguyen, Lionel Mourey, Terwilliger T. C.. A Comprehensive Review on Mycobacterium tuberculosis Targets and Drug Development from a Structural Perspective. Structural Biology in Drug Discovery, Wiley, 2020, ⟨10.1002/9781118681121.ch23⟩. ⟨hal-02950595⟩
  • Gilles Prévost, Lionel Mourey, Didier Colin, Henri Monteil, Mauro Dalla Serra, et al.. Alpha-helix and beta-barrel pore-forming toxins (leucocidins, alpha-, gamma-, and delta-cytolysins) of Staphylococcus aureus. Joseph E. Alouf; Michel R. Popoff. The Comprehensive Sourcebook of Bacterial Protein Toxins, Elsevier, pp.590-607, 2006, 978-0-12-088445-2. ⟨10.1016/B978-012088445-2/50037-8⟩. ⟨hal-03003432⟩