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Unexpected protective role for Toll-like receptor 3 in the arterial wall.

Jennifer E Cole , Tina J Navin , Amanda J Cross , Michael E Goddard , Lena Alexopoulou , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (6), pp.2372-7. ⟨10.1073/pnas.1018515108⟩
Article dans une revue hal-00609592v1
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Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1

Suzana P Salcedo , María Ines Marchesini , Hugues Lelouard , Emilie Fugier , Gilles Jolly , et al.
PLoS Pathogens, 2008, 4 (2), pp.e21. ⟨10.1371/journal.ppat.0040021⟩
Article dans une revue hal-00294210v1
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TLR7 Signaling Drives the Development of Sjögren’s Syndrome

Yawen Wang , Annie Roussel-Queval , Lionel Chasson , Noël Hanna Kazazian , Laetitia Marcadet , et al.
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.676010⟩
Article dans une revue hal-03454314v1
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Detrimental contribution of the immuno-inhibitor b7-h1 to rabies virus encephalitis.

Monique Lafon , Françoise Mégret , Sven G Meuth , Ole Simon , Myriam L Velandia Romero , et al.
Journal of Immunology, 2008, 180 (11), pp.7506-15. ⟨10.4049/jimmunol.180.11.7506⟩
Article dans une revue pasteur-00293348v1

Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis.

Philippe P Pagni , Stephanie Traub , Olivier Demaria , Lionel Chasson , Lena Alexopoulou
Autoimmunity, 2010, 43 (4), pp.275-87. ⟨10.3109/08916930903509056⟩
Article dans une revue hal-00502973v1

Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila.

Kristina A Archer , Lena Alexopoulou , Richard A Flavell , Craig R Roy
Cellular Microbiology, 2009, 11 (1), pp.21-36. ⟨10.1111/j.1462-5822.2008.01234.x⟩
Article dans une revue hal-00402930v1

Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection.

Nasiema Allie , Lena Alexopoulou , Valérie Quesniaux , Lizette Fick , Ksanthi Kranidioti , et al.
Immunology, 2008, epub ahead of print. ⟨10.1111/j.1365-2567.2008.02865.x⟩
Article dans une revue hal-00318573v1

Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis.

Pietro Fazzari , Junia Penachioni , Sara Gianola , Ferdinando Rossi , Britta J Eickholt , et al.
BMC Developmental Biology, 2007, 7, pp.55. ⟨10.1186/1471-213X-7-55⟩
Article dans une revue hal-00165510v1

Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury.

Hordur S Hardarson , J Scott Baker , Zhao Yang , Enkhsaikhan Purevjav , Chien-Hua Huang , et al.
AJP - Heart and Circulatory Physiology, 2007, 292 (1), pp.H251-8. ⟨10.1152/ajpheart.00398.2006⟩
Article dans une revue hal-00165354v1
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Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei

Khatoun Al Moussawi , Eric Ghigo , Ulrich Kalinke , Lena Alexopoulou , Jean-Louis Mege , et al.
PLoS Pathogens, 2010, 6 (1), pp.e1000722. ⟨10.1371/journal.ppat.1000722⟩
Article dans une revue hal-00502930v1

PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation.

Iñigo Tirapu , Benoit Giquel , Lena Alexopoulou , Satoshi Uematsu , Richard A. Flavell , et al.
International Immunology, 2009, 21 (7), pp.871-9. ⟨10.1093/intimm/dxp053⟩
Article dans une revue hal-00432092v1

Inflammatory regulation by TLR3 in acute hepatitis.

Xiaoyan Xiao , Peng Zhao , Daniel Rodriguez-Pinto , Dake Qi , Octavian Henegariu , et al.
Journal of Immunology, 2009, 183 (6), pp.3712-9. ⟨10.4049/jimmunol.0901221⟩
Article dans une revue hal-00431899v1

[Toll-like receptor 8: the awkward TLR].

Lena Alexopoulou , Benoit Desnues , Olivier Demaria
Médecine/Sciences, 2012, 28 (1), pp.96-102. ⟨10.1051/medsci/2012281023⟩
Article dans une revue hal-00685835v1

Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells.

Martin Guilliams , Karine Crozat , Sandrine Henri , Samira Tamoutounour , Pierre Grenot , et al.
Blood, 2010, 115 (10), pp.1958-68. ⟨10.1182/blood-2009-09-245274⟩
Article dans une revue hal-00502990v1

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA.

Ivan Perrot , Florence Deauvieau , Catherine Massacrier , Nicola Hughes , Pierre Garrone , et al.
Journal of Immunology, 2010, 185 (4), pp.2080-8. ⟨10.4049/jimmunol.1000532⟩
Article dans une revue hal-00553598v1

Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection.

Nicolas Zucchini , Gilles Bessou , Stephanie Traub , Scott H Robbins , Satoshi Uematsu , et al.
Journal of Immunology, 2008, 180 (9), pp.5799-803
Article dans une revue hal-00294063v1

Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals.

Jill S Cameron , Lena Alexopoulou , Jacob A Sloane , Allitia B Dibernardo , Yinghua Ma , et al.
Journal of Neuroscience, 2007, 27 (47), pp.13033-41. ⟨10.1523/JNEUROSCI.4290-06.2007⟩
Article dans une revue hal-00295070v1
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Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice.

Nicole C Stowell , Jonathan Seideman , Holly A Raymond , Karen A Smalley , Roberta J Lamb , et al.
Respiratory Research, 2009, 10, pp.43. ⟨10.1186/1465-9921-10-43⟩
Article dans une revue hal-00432116v1

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo

Sethuraman Subramanian , Clara Jana-Lui Busch , Kaaweh Molawi , Laufey Geirsdottir , Julien Maurizio , et al.
Nature Immunology, 2022, 23 (3), pp.458-468. ⟨10.1038/s41590-022-01146-w⟩
Article dans une revue hal-03664920v1

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

Zeynep Dogusan , Mónica García , Daisy Flamez , Lena Alexopoulou , Michel Goldman , et al.
Diabetes, 2008, 57 (5), pp.1236-45. ⟨10.2337/db07-0844⟩
Article dans une revue hal-00294097v1
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Sex Bias in Susceptibility to MCMV Infection: Implication of TLR9

Stephanie Traub , Olivier Demaria , Lionel Chasson , Fabienne Serra , Benoit Desnues , et al.
PLoS ONE, 2012, 7 (9), pp.e45171. ⟨10.1371/journal.pone.0045171⟩
Article dans une revue hal-02022455v1

TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice

Amber M. Paul , Dhiraj Acharya , Linda Le , Penghua Wang , Dobrivoje S. Stokic , et al.
Journal of Immunology, 2016, 197 (11), pp.4425-4435. ⟨10.4049/jimmunol.1600902⟩
Article dans une revue hal-01438479v1
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The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling

Benoit Desnues , Amanda B Macedo , Diana Ordoñez-Rueda , Annie Roussel-Queval , Bernard Malissen , et al.
European Journal of Immunology, 2016, 46 (12), pp.2801-2811. ⟨10.1002/eji.201646573⟩
Article dans une revue hal-03475080v1

TLR8 deficiency leads to autoimmunity in mice.

Olivier Demaria , Philippe P Pagni , Stephanie Traub , Aude de Gassart , Nora Branzk , et al.
Journal of Clinical Investigation, 2010, 120 (10), pp.3651-62. ⟨10.1172/JCI42081⟩
Article dans une revue hal-00553587v1

Brucella abortus induces Irgm3 and Irga6 expression via type-I IFN by a MyD88-dependent pathway, without the requirement of TLR2, TLR4, TLR5 and TLR9.

Nicolas Lapaque , Alexandre Muller , Lena Alexopoulou , Jonathan C Howard , Jean-Pierre Gorvel
Microbial Pathogenesis, 2009, epub ahead of print. ⟨10.1016/j.micpath.2009.09.005⟩
Article dans une revue istex hal-00431861v1
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Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling

Noël Hanna Kazazian , Yawen Wang , Annie Roussel-Queval , Laetitia Marcadet , Lionel Chasson , et al.
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.02015⟩
Article dans une revue hal-03454363v1

TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules.

Brian B Gowen , Min-Hui Wong , Kie-Hoon Jung , Andrew B Sanders , William M Mitchell , et al.
Journal of Immunology, 2007, 178 (8), pp.5200-8
Article dans une revue hal-00165500v1

Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity.

Lena Alexopoulou , Ksanthi Kranidioti , Sofia Xanthoulea , Maria Denis , Anastasia Kotanidou , et al.
European Journal of Immunology, 2006, 36 (10), pp.2768-80. ⟨10.1002/eji.200635921⟩
Article dans une revue hal-00165609v1

Cutting edge: Priming of NK cells by IL-18.

Julie Chaix , Marlowe S Tessmer , Kasper Hoebe , Nicolas Fuséri , Bernhard Ryffel , et al.
Journal of Immunology, 2008, 181 (3), pp.1627-31
Article dans une revue hal-00363717v1
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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2

Christina Fieber , Marton Janos , Tina Koestler , Nina Gratz , Xiao-Dong Li , et al.
PLoS ONE, 2015, 10 (e0119727), ⟨10.1371/journal.pone.0119727.s001⟩
Article dans une revue hal-01218062v1