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Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.

 David M Kristensen , Laurianne Lesné , V. Le Fol , Christele Desdoits-Lethimonier , Nathalie Dejucq-Rainsford , et al.
International Journal of Andrology, 2012, 35 (3), pp.377-84. ⟨10.1111/j.1365-2605.2012.01282.x⟩
Article dans une revue hal-00876956v1
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Many putative endocrine disruptors inhibit prostaglandin synthesis.

 David M. Kristensen , Maria L. Skalkam , Karine Audouze , Laurianne Lesné , Christele Desdoits-Lethimonier , et al.
Environmental Health Perspectives, 2011, 119 (4), pp.534-41. ⟨10.1289/ehp.1002635⟩
Article dans une revue hal-00682736v1

Direct evidence that phtalate esters inhibit human testosterone production

 Christele Desdoits , Laurianne Lesné , Elisabeth Perdu , Daniel Zalko , Bruno Le Bizec , et al.
5th Copenhagen Workshop on Endocrine Disrupters, May 2009, Copenhagen, Denmark
Communication dans un congrès hal-00670879v1

Paracetamol, aspirin, and indomethacin display endocrine disrupting properties in the adult human testis in vitro.

 Océane Albert , Christele Desdoits-Lethimonier , Laurianne Lesné , Alain Legrand , François Guillé , et al.
Human Reproduction, 2013, 28 (7), pp.1890-8. ⟨10.1093/humrep/det112⟩
Article dans une revue inserm-00866016v1
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Pre- and postnatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice.

 Anthony Laugeray , Ameziane Herzine , Olivier Perche , Betty Hébert , Marine Aguillon-Naury , et al.
Frontiers in Behavioral Neuroscience, 2014, 8, pp.390. ⟨10.3389/fnbeh.2014.00390⟩
Article dans une revue hal-01121829v1
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Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.

 François Chauvigné , Simon Plummer , Laurianne Lesné , Jean Pierre J. P. Cravedi , Nathalie Dejucq-Rainsford , et al.
PLoS ONE, 2011, 6 (11), pp.e27172. ⟨10.1371/journal.pone.0027172⟩
Article dans une revue hal-00682585v1

Parallel assessment of BPA and BPA-substitutes on the human Leydig cell function

 Christele Desdoits-Lethimonier , Laurianne Lesné , Séverine Mazaud-Guittot , Karim Bensalah , Christian Platel , et al.
19th European Testis Workshop, Jun 2016, Saint Malô, France
Communication dans un congrès hal-02439021v1

Parallel assessment of BPA and BPA-substitutes on the adult human Leydig cell function.

 Christele Desdoits-Lethimonier , Laurianne Lesne , Séverine Mazaud-Guittot , Karim Bensalah , Christian Platel , et al.
19th European Testis workshop, Jun 2016, Saint-Malo, France
Poster de conférence hal-02439416v1

Antiepileptic drugs are endocrine disruptors for the human fetal testis ex vivo

 Laurianne Lesné , Christèle Desdoits-Lethimonier , Elisa Hug , Nathalie Costet , Léo Raffenne , et al.
Toxicological Sciences, 2023, ⟨10.1093/toxsci/kfad076⟩
Article dans une revue hal-04190597v1

Ibuprofen and Men

 David Moberg Kristensen , Christele Desdoits-Lethimonier , Abigail Mackey , Marlene Dalgaard , Federico De Masi , et al.
20th European Testis Workshop, May 2018, Obidos, Portugal
Communication dans un congrès hal-02438972v1
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An investigation of the endocrine-disruptive effects of bisphenol A in human and rat fetal testes.

 Millissia Ben Maamar , Laurianne Lesné , Christèle Desdoits-Lethimonier , Isabelle Coiffec , Julie Lassurguère , et al.
PLoS ONE, 2015, 10 (2), pp.e0117226. ⟨10.1371/journal.pone.0117226⟩
Article dans une revue hal-01121759v1
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Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro

 François Chauvigné , Arnaud Menuet , Laurianne Lesné , Marie-Christine Chagnon , Cécile Chevrier , et al.
Environmental Health Perspectives, 2009, 117 (4), pp.515-21. ⟨10.1289/ehp.11870⟩
Article dans une revue hal-00669512v1
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In utero and lactational exposure to low-doses of the pyrethroid insecticide cypermethrin leads to neurodevelopmental defects in male mice-An ethological and transcriptomic study

 Anthony Laugeray , Ameziane Herzine , Olivier Perche , Olivier Richard , Céline Montecot-Dubourg , et al.
PLoS ONE, 2017, 12 (10), pp.e0184475. ⟨10.1371/journal.pone.0184475⟩
Article dans une revue hal-03477436v1
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Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders

 Lauriane Sèdes , Christele Desdoits-Lethimonier , Betty Rouaisnel , Hélène Holota , Laura Thirouard , et al.
Stem Cell Reports, 2018, 11 (4), pp.944-958. ⟨10.1016/j.stemcr.2018.08.018⟩
Article dans une revue hal-01888869v1

Endocrine disruptive effects of ibuprofen on the human testis from fetal life to adulthood

 Millissia Ben Maamar , Christele Desdoits-Lethimonier , Laurianne Lesné , Antoine D. Rolland , Isabelle Coiffec , et al.
8th Copenhaguen Workshop on Endocrine Disrupters, May 2015, Copenhagen, Denmark
Poster de conférence hal-02439939v1

Ibuprofen disrupts the endocrine function of the human adult testis.

 Christele Desdoits-Lethimonier , Laurianne Lesne , Séverine Mazaud-Guittot , Millissia Ben Maamar , D.M. Kristensen , et al.
Journée du GRD Repro, Apr 2015, Rennes, France
Poster de conférence hal-02439947v1
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Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

 Pierre Gaudriault , Séverine Mazaud-Guittot , Vincent Lavoué , Isabelle Coiffec , Laurianne Lesné , et al.
Environmental Health Perspectives, 2017, 125 (8), pp.087004. ⟨10.1289/EHP1014⟩
Article dans une revue hal-01579609v1

Perinatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice

 Anthony Laugeray , Ameziane Herzine , Olivier Perche , Olivier Richard , Arnaud Menuet , et al.
Toxicology Letters, 2014, 229, pp.S43. ⟨10.1016/j.toxlet.2014.06.191⟩
Article dans une revue hal-03477652v1

Cyp17a1 expression and CYP17 lyase activity as targets to mono-(2-ethylhexyl) phthalate in the rat fetal testis

 François Chauvigné , Laurianne Lesné , Simon Plummer , Jean Pierre J. P. Cravedi , Nathalie Dejucq-Rainsford , et al.
17. European Testis Workshop, Apr 2012, Djurönäset, Sweden. 2012
Poster de conférence hal-02747118v1

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

 David Møbjerg Kristensen , Ulla Hass , Laurianne Lesné , Grete Lottrup , Pernille Rosenskjold Jacobsen , et al.
Human Reproduction, 2011, 26 (1), pp.235-44. ⟨10.1093/humrep/deq323⟩
Article dans une revue hal-00682685v1

Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects

 David M. Kristensen , Séverine Mazaud-Guittot , Pierre Gaudriault , Laurianne Lesné , Tania Serrano , et al.
Nature Reviews Endocrinology, 2016, 12 (7), pp.381--393. ⟨10.1038/nrendo.2016.55⟩
Article dans une revue hal-01359566v1

Fluorinated alkyl substances and technical mixtures used in food paper-packaging exhibit endocrine-related activity in vitro

 A.K. Rosenmai , C. Taxvig , T. Svingen , X. Trier , B.M.A. Van Vugt-Lussenburg , et al.
Andrology, 2016, 4 (4), pp.662--672. ⟨10.1111/andr.12190⟩
Article dans une revue hal-01367144v1
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Parallel assessment of the effects of bisphenol A and several of its analogs on the adult human testis

 Christèle Desdoits-Lethimonier , Lauriane Lesné , Pierre Gaudriault , Daniel Zalko , Jean-Philippe Antignac , et al.
Human Reproduction, 2017, 32 (7), pp.1465--1473. ⟨10.1093/humrep/dex093⟩
Article dans une revue hal-01578582v1
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Human testis steroidogenesis is inhibited by phthalates.

 Christele Desdoits-Lethimonier , Océane Albert , Bruno Le Bizec , Elisabeth Perdu , Daniel Zalko , et al.
Human Reproduction, 2012, 27 (5), pp.1451-9. ⟨10.1093/humrep/des069⟩
Article dans une revue hal-00876965v1

Effects of antiepileptic drugs on the human fetal testis ex vivo

 L. Lesne , C. Desdoits , E. Hug , M. Toupin , I. Kugathas , et al.
Toxicology Letters, 2022, 368, pp.S114-S114. ⟨10.1016/j.toxlet.2022.07.321⟩
Article dans une revue hal-03798959v1
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Ibuprofen results in alterations of human fetal testis development

 M. Ben Maamar , Lauriane Lesné , K. Hennig , C. Desdoits-Lethimonier , K.R. Kilcoyne , et al.
Scientific Reports, 2017, 7 (1), pp.44184. ⟨10.1038/srep44184⟩
Article dans une revue hal-01517095v1
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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

 David Mobjerg Kristensen , Christele Desdoits-Lethimonier , Abigail L. Mackey , Marlene Danner Dalgaard , Federico de Masi , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (4), pp.E715-E724. ⟨10.1073/pnas.1715035115⟩
Article dans une revue hal-01710995v1

Ibuprofen targets several cell types in the human fetal testis.

 Millissia Ben Maamar , Laurianne Lesne , Antoine D. Rolland , I. Coiffec , Christele Desdoits-Lethimonier , et al.
Journée du GRD Repro, Apr 2015, Rennes, France
Poster de conférence hal-02439945v1
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Acetaminophen (APAP, paracetamol) interferes with the first trimester human fetal ovary development in an ex vivo model

 Laetitia L Lecante , Sabrina Leverrier-Penna , Thomas Gicquel , Frank Giton , Nathalie Costet , et al.
Journal of Clinical Endocrinology and Metabolism, 2022, 107 (6), pp.1647-1661. ⟨10.1210/clinem/dgac080⟩
Article dans une revue hal-03578173v1
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