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Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.
David M Kristensen
,
Laurianne Lesné
,
V. Le Fol
,
Christele Desdoits-Lethimonier
,
Nathalie Dejucq-Rainsford
,
et al.
Article dans une revue
hal-00876956v1
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Many putative endocrine disruptors inhibit prostaglandin synthesis.
David M. Kristensen
,
Maria L. Skalkam
,
Karine Audouze
,
Laurianne Lesné
,
Christele Desdoits-Lethimonier
,
et al.
Article dans une revue
hal-00682736v1
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Direct evidence that phtalate esters inhibit human testosterone production
Christele Desdoits
,
Laurianne Lesné
,
Elisabeth Perdu
,
Daniel Zalko
,
Bruno Le Bizec
,
et al.
5th Copenhagen Workshop on Endocrine Disrupters, May 2009, Copenhagen, Denmark
Communication dans un congrès
hal-00670879v1
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Paracetamol, aspirin, and indomethacin display endocrine disrupting properties in the adult human testis in vitro.
Océane Albert
,
Christele Desdoits-Lethimonier
,
Laurianne Lesné
,
Alain Legrand
,
François Guillé
,
et al.
Article dans une revue
inserm-00866016v1
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Pre- and postnatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice.
Anthony Laugeray
,
Ameziane Herzine
,
Olivier Perche
,
Betty Hébert
,
Marine Aguillon-Naury
,
et al.
Article dans une revue
hal-01121829v1
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Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.
François Chauvigné
,
Simon Plummer
,
Laurianne Lesné
,
Jean Pierre J. P. Cravedi
,
Nathalie Dejucq-Rainsford
,
et al.
Article dans une revue
hal-00682585v1
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Parallel assessment of BPA and BPA-substitutes on the human Leydig cell function
Christele Desdoits-Lethimonier
,
Laurianne Lesné
,
Séverine Mazaud-Guittot
,
Karim Bensalah
,
Christian Platel
,
et al.
19th European Testis Workshop, Jun 2016, Saint Malô, France
Communication dans un congrès
hal-02439021v1
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Parallel assessment of BPA and BPA-substitutes on the adult human Leydig cell function.
Christele Desdoits-Lethimonier
,
Laurianne Lesne
,
Séverine Mazaud-Guittot
,
Karim Bensalah
,
Christian Platel
,
et al.
19th European Testis workshop, Jun 2016, Saint-Malo, France
Poster de conférence
hal-02439416v1
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Antiepileptic drugs are endocrine disruptors for the human fetal testis ex vivo
Laurianne Lesné
,
Christèle Desdoits-Lethimonier
,
Elisa Hug
,
Nathalie Costet
,
Léo Raffenne
,
et al.
Article dans une revue
hal-04190597v1
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Ibuprofen and Men
David Moberg Kristensen
,
Christele Desdoits-Lethimonier
,
Abigail Mackey
,
Marlene Dalgaard
,
Federico De Masi
,
et al.
20th European Testis Workshop, May 2018, Obidos, Portugal
Communication dans un congrès
hal-02438972v1
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An investigation of the endocrine-disruptive effects of bisphenol A in human and rat fetal testes.
Millissia Ben Maamar
,
Laurianne Lesné
,
Christèle Desdoits-Lethimonier
,
Isabelle Coiffec
,
Julie Lassurguère
,
et al.
Article dans une revue
hal-01121759v1
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Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro
François Chauvigné
,
Arnaud Menuet
,
Laurianne Lesné
,
Marie-Christine Chagnon
,
Cécile Chevrier
,
et al.
Article dans une revue
hal-00669512v1
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In utero and lactational exposure to low-doses of the pyrethroid insecticide cypermethrin leads to neurodevelopmental defects in male mice-An ethological and transcriptomic study
Anthony Laugeray
,
Ameziane Herzine
,
Olivier Perche
,
Olivier Richard
,
Céline Montecot-Dubourg
,
et al.
Article dans une revue
hal-03477436v1
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Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders
Lauriane Sèdes
,
Christele Desdoits-Lethimonier
,
Betty Rouaisnel
,
Hélène Holota
,
Laura Thirouard
,
et al.
Article dans une revue
hal-01888869v1
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Endocrine disruptive effects of ibuprofen on the human testis from fetal life to adulthood
Millissia Ben Maamar
,
Christele Desdoits-Lethimonier
,
Laurianne Lesné
,
Antoine D. Rolland
,
Isabelle Coiffec
,
et al.
8th Copenhaguen Workshop on Endocrine Disrupters, May 2015, Copenhagen, Denmark
Poster de conférence
hal-02439939v1
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Ibuprofen disrupts the endocrine function of the human adult testis.
Christele Desdoits-Lethimonier
,
Laurianne Lesne
,
Séverine Mazaud-Guittot
,
Millissia Ben Maamar
,
D.M. Kristensen
,
et al.
Journée du GRD Repro, Apr 2015, Rennes, France
Poster de conférence
hal-02439947v1
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Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants
Pierre Gaudriault
,
Séverine Mazaud-Guittot
,
Vincent Lavoué
,
Isabelle Coiffec
,
Laurianne Lesné
,
et al.
Article dans une revue
hal-01579609v1
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Perinatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice
Anthony Laugeray
,
Ameziane Herzine
,
Olivier Perche
,
Olivier Richard
,
Arnaud Menuet
,
et al.
Article dans une revue
hal-03477652v1
|
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Cyp17a1 expression and CYP17 lyase activity as targets to mono-(2-ethylhexyl) phthalate in the rat fetal testis
François Chauvigné
,
Laurianne Lesné
,
Simon Plummer
,
Jean Pierre J. P. Cravedi
,
Nathalie Dejucq-Rainsford
,
et al.
17. European Testis Workshop, Apr 2012, Djurönäset, Sweden. 2012
Poster de conférence
hal-02747118v1
|
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Effects of antiepileptic drugs on the human fetal testis ex vivo
L. Lesne
,
C. Desdoits
,
E. Hug
,
M. Toupin
,
I. Kugathas
,
et al.
Article dans une revue
hal-03798959v1
|
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Ibuprofen results in alterations of human fetal testis development
M. Ben Maamar
,
Lauriane Lesné
,
K. Hennig
,
C. Desdoits-Lethimonier
,
K.R. Kilcoyne
,
et al.
Article dans une revue
hal-01517095v1
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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism
David Mobjerg Kristensen
,
Christele Desdoits-Lethimonier
,
Abigail L. Mackey
,
Marlene Danner Dalgaard
,
Federico de Masi
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (4), pp.E715-E724. ⟨10.1073/pnas.1715035115⟩
Article dans une revue
hal-01710995v1
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Ibuprofen targets several cell types in the human fetal testis.
Millissia Ben Maamar
,
Laurianne Lesne
,
Antoine D. Rolland
,
I. Coiffec
,
Christele Desdoits-Lethimonier
,
et al.
Journée du GRD Repro, Apr 2015, Rennes, France
Poster de conférence
hal-02439945v1
|
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Acetaminophen (APAP, paracetamol) interferes with the first trimester human fetal ovary development in an ex vivo model
Laetitia L Lecante
,
Sabrina Leverrier-Penna
,
Thomas Gicquel
,
Frank Giton
,
Nathalie Costet
,
et al.
Article dans une revue
hal-03578173v1
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Fluorinated alkyl substances and technical mixtures used in food paper-packaging exhibit endocrine-related activity in vitro
A.K. Rosenmai
,
C. Taxvig
,
T. Svingen
,
X. Trier
,
B.M.A. Van Vugt-Lussenburg
,
et al.
Article dans une revue
hal-01367144v1
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Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects
David M. Kristensen
,
Séverine Mazaud-Guittot
,
Pierre Gaudriault
,
Laurianne Lesné
,
Tania Serrano
,
et al.
Article dans une revue
hal-01359566v1
|
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Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.
David Møbjerg Kristensen
,
Ulla Hass
,
Laurianne Lesné
,
Grete Lottrup
,
Pernille Rosenskjold Jacobsen
,
et al.
Article dans une revue
hal-00682685v1
|
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Parallel assessment of the effects of bisphenol A and several of its analogs on the adult human testis
Christèle Desdoits-Lethimonier
,
Lauriane Lesné
,
Pierre Gaudriault
,
Daniel Zalko
,
Jean-Philippe Antignac
,
et al.
Article dans une revue
hal-01578582v1
|
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Human testis steroidogenesis is inhibited by phthalates.
Christele Desdoits-Lethimonier
,
Océane Albert
,
Bruno Le Bizec
,
Elisabeth Perdu
,
Daniel Zalko
,
et al.
Article dans une revue
hal-00876965v1
|
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