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The Mycobacterium tuberculosis GroEL1 chaperone is a substrate of Ser/Thr protein kinases.

Marc J Canova , Laurent Kremer , Virginie Molle
Journal of Bacteriology, 2009, 191 (8), pp.2876-83. ⟨10.1128/JB.01569-08⟩
Article dans une revue hal-00373654v1

The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria.

Anuradha Alahari , Nathalie Saint , Sylvie Campagna , Virginie Molle , Gérard Molle , et al.
Journal of Bacteriology, 2007, 189 (17), pp.6351-6358. ⟨10.1128/JB.00509-07⟩
Article dans une revue hal-00167441v1

Antimycobacterial activity and mechanism of action of NAS-91.

Paul Gratraud , Namita Surolia , Gurdyal Besra , Avadhesha Surolia , Laurent Kremer
Antimicrobial Agents and Chemotherapy, 2007, epub ahead of print. ⟨10.1128/AAC.00968-07⟩
Article dans une revue hal-00202871v1
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Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

Matthias Richard , Ana Victoria Gutiérrez , Albertus Viljoen , Eric Ghigo , Mickaël Blaise , et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00649⟩
Article dans une revue hal-02137555v1

Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

Matthias Richard , Ana Victoria Gutiérrez , Albertus Viljoen , Daniela Rodriguez-Rincon , Françoise Roquet-Banères , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63 (1), ⟨10.1128/AAC.01316-18⟩
Article dans une revue hal-02137498v1
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The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold

Kien Lam Ung , Husam Alsarraf , Laurent Kremer , Mickael Blaise
Proteins - Structure, Function and Bioinformatics, 2020, 88 (6), pp.809-815. ⟨10.1002/prot.25863⟩
Article dans une revue hal-02988326v1
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CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model

Matt D Johansen , Laurent Kremer
Frontiers in Cellular and Infection Microbiology, 2020, 10, pp.357. ⟨10.3389/fcimb.2020.00357⟩
Article dans une revue inserm-02971833v1
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1 H -benzo[ d ]imidazole derivatives affect MmpL3 in Mycobacterium tuberculosis

Małgorzata Korycka-Machała , Albertus Viljoen , Jakub Pawełczyk , Paulina Borówka , Bożena Dziadek , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63, pp.441 - 460. ⟨10.1128/AAC.00441-19⟩
Article dans une revue hal-02202451v1

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

Laeticia Alibaud , Yoann Rombouts , Xavier Trivelli , Adeline Burguière , S. L. G. Cirillo , et al.
Molecular Microbiology, 2011, 80 (4), pp.919-934. ⟨10.1111/j.1365-2958.2011.07618.x⟩
Article dans une revue hal-00641589v1
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Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum Specimens

Pratt Kolia-Diafouka , Sylvain Godreuil , Arnaud Bourdin , Severine Carrer-Kremer , Laurent Kremer , et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.02224⟩
Article dans une revue hal-01887123v1
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Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

Estalina Báez-Ramírez , Luis Querales , Carlos Andres Aranaga , Gustavo López , Elba Guerrero , et al.
The Cell Surface, 2021, 7, pp.100060. ⟨10.1016/j.tcsw.2021.100060⟩
Article dans une revue inserm-03381892v2

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

Anil K Ojha , Anthony D Baughn , Dhinakaran Sambandan , Tsungda Hsu , Xavier Trivelli , et al.
Molecular Microbiology, 2008, 69 (1), pp.164-174. ⟨10.1111/j.1365-2958.2008.06274.x⟩
Article dans une revue hal-00292249v1
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Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

Catherine Vilchèze , Virginie Molle , Severine Carrere-Kremer , Jade Leiba , Lionel Mourey , et al.
PLoS Pathogens, 2014, 10 (5), pp.e1004115. ⟨10.1371/journal.ppat.1004115⟩
Article dans une revue hal-02282645v1

Identification by surface plasmon resonance of the mycobacterial lipomannan and lipoarabinomannan domains involved in binding to CD14 and LPS-binding protein.

Elisabeth Elass , Bernadette Coddeville , Yann Guerardel , Laurent Kremer , Emmanuel Maes , et al.
FEBS Letters, 2007, 581 (7), pp.1383-90. ⟨10.1016/j.febslet.2007.02.056⟩
Article dans une revue hal-00149417v1

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

Iman Halloum , Severine Carrere-Kremer , Mickaël Blaise , Albertus Viljoen , Audrey Bernut , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (29), pp.E4228-E4237. ⟨10.1073/pnas.1605477113⟩
Article dans une revue hal-02086925v1
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Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening

Léo Faion , Kamel Djaout , Rosangela Frita , Catalin Pintiala , Francois-Xavier Cantrelle , et al.
European Journal of Medicinal Chemistry, 2020, 200, pp.112440. ⟨10.1016/j.ejmech.2020.112440⟩
Article dans une revue hal-02988077v1

Overexpression of the Salmonella KdpF membrane peptide modulates expression of kdp genes and intramacrophage growth

Laila Gannoun-Zaki , Claudine Belon , Christian Dupont , Friederike Hilbert , Laurent Kremer , et al.
FEMS Microbiology Letters, 2014, 359 (1), pp.34-41. ⟨10.1111/1574-6968.12559⟩
Article dans une revue hal-02281803v1
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From the Characterization of the Four Serine/Threonine Protein Kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the Role of PknA and PknB in Cell Division.

Maria Fiuza , Marc J Canova , Isabelle Zanella-Cléon , Michel Becchi , Alain J Cozzone , et al.
Journal of Biological Chemistry, 2008, 283 (26), pp.18099-112. ⟨10.1074/jbc.M802615200⟩
Article dans une revue hal-00292250v1

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts

Vipul K. Singh , Laurence Berry , Audrey Bernut , Shubhra Singh , Severine Carrere-Kremer , et al.
Cellular Microbiology, 2016, 18 (11), pp.1489-1507. ⟨10.1111/cmi.12606⟩
Article dans une revue hal-01453293v1

Point Mutations within the Fatty Acid Synthase Type II Dehydratase Components HadA or HadC Contribute to Isoxyl Resistance in Mycobacterium tuberculosis

Laila Gannoun-Zaki , Laeticia Alibaud , Laurent Kremer
Antimicrobial Agents and Chemotherapy, 2012, 57 (1), pp.629-632. ⟨10.1128/AAC.01972-12⟩
Article dans une revue hal-02281787v1
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In Vivo Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (7), pp.4054-4063. ⟨10.1128/AAC.00142-14⟩
Article dans une revue hal-02088311v1

X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).

Sudharsan Sridharan , Lei Wang , Alistair K Brown , Lynn G Dover , Laurent Kremer , et al.
Journal of Molecular Biology, 2007, 366 (2), pp.469-80. ⟨10.1016/j.jmb.2006.11.006⟩
Article dans une revue hal-00148924v1
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Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Jérôme Ruyck , Christian Dupont , Elodie Lamy , Vincent Le Moigne , Christophe Biot , et al.
ChemistryOpen, 2020, 9 (3), pp.351-365. ⟨10.1002/open.202000042⟩
Article dans une revue hal-02988322v1
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Mycobacterium abscessus, un modèle de résistance aux différentes classes d’antibiotiques

Morgane Illouz , Matthéo Alcaraz , Françoise Roquet-Banères , Laurent Kremer
Médecine/Sciences, 2021, 37 (11), pp.993-1001. ⟨10.1051/medsci/2021164⟩
Article dans une revue hal-03462547v1
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Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline

Jaryd R Sullivan , Andréanne Lupien , Elias Kalthoff , Claire Hamela , Lorne Taylor , et al.
PLoS Pathogens, 2021, 17 (10), pp.e1009965. ⟨10.1371/journal.ppat.1009965⟩
Article dans une revue inserm-03381888v1

An improved method to unravel phosphoacceptors in Ser/Thr protein kinase-phosphorylated substrates

Virginie Molle , Jade Leiba , Isabelle Zanella-Cléon , Michel Becchi , Laurent Kremer
Proteomics, 2010, 10 (21), pp.3910-3915. ⟨10.1002/pmic.201000316⟩
Article dans une revue istex hal-02282736v1
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Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains

Pierre Santucci , Nabil Smichi , Sadia Diomandé , Isabelle Poncin , Vanessa Point , et al.
FEBS Journal, 2019, ⟨10.1111/febs.14864⟩
Article dans une revue hal-02137694v1
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Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus

Tanja Küssau , Niël van Wyk , Matt D Johansen , Husam M. A. B. Alsarraf , Aymeric Neyret , et al.
Cells, 2020, 9 (11), pp.2410. ⟨10.3390/cells9112410⟩
Article dans une revue inserm-02988325v1

Design, synthesis, anti‐mycobacterial and cytotoxic evaluation of C‐4 functionalized 1,8‐naphthalimide‐heterocyclic hydrazide conjugates

Shalini Shalini , Matt Johansen , Laurent Kremer , Vipan Kumar
Chemical Biology and Drug Design, 2019, 94 (1), pp.1300-1305. ⟨10.1111/cbdd.13503⟩
Article dans une revue inserm-02480347v1
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Mycobacterium abscessus

Yves-Marie Boudehen , Laurent Kremer
Trends in Microbiology, 2021, 29 (10), pp.951-952. ⟨10.1016/j.tim.2021.06.006⟩
Article dans une revue inserm-03381908v1