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The Mycobacterium tuberculosis GroEL1 chaperone is a substrate of Ser/Thr protein kinases.

Marc J Canova , Laurent Kremer , Virginie Molle
Journal of Bacteriology, 2009, 191 (8), pp.2876-83. ⟨10.1128/JB.01569-08⟩
Article dans une revue hal-00373654v1

The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria.

Anuradha Alahari , Nathalie Saint , Sylvie Campagna , Virginie Molle , Gérard Molle , et al.
Journal of Bacteriology, 2007, 189 (17), pp.6351-6358. ⟨10.1128/JB.00509-07⟩
Article dans une revue hal-00167441v1

Antimycobacterial activity and mechanism of action of NAS-91.

Paul Gratraud , Namita Surolia , Gurdyal Besra , Avadhesha Surolia , Laurent Kremer
Antimicrobial Agents and Chemotherapy, 2007, epub ahead of print. ⟨10.1128/AAC.00968-07⟩
Article dans une revue hal-00202871v1
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Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

Matthias Richard , Ana Victoria Gutiérrez , Albertus Viljoen , Eric Ghigo , Mickaël Blaise , et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00649⟩
Article dans une revue hal-02137555v1

Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

Matthias Richard , Ana Victoria Gutiérrez , Albertus Viljoen , Daniela Rodriguez-Rincon , Françoise Roquet-Banères , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63 (1), ⟨10.1128/AAC.01316-18⟩
Article dans une revue hal-02137498v1
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The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold

Kien Lam Ung , Husam Alsarraf , Laurent Kremer , Mickael Blaise
Proteins - Structure, Function and Bioinformatics, 2020, 88 (6), pp.809-815. ⟨10.1002/prot.25863⟩
Article dans une revue hal-02988326v1
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CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model

Matt D Johansen , Laurent Kremer
Frontiers in Cellular and Infection Microbiology, 2020, 10, pp.357. ⟨10.3389/fcimb.2020.00357⟩
Article dans une revue inserm-02971833v1
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1 H -benzo[ d ]imidazole derivatives affect MmpL3 in Mycobacterium tuberculosis

Małgorzata Korycka-Machała , Albertus Viljoen , Jakub Pawełczyk , Paulina Borówka , Bożena Dziadek , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63, pp.441 - 460. ⟨10.1128/AAC.00441-19⟩
Article dans une revue hal-02202451v1

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

Laeticia Alibaud , Yoann Rombouts , Xavier Trivelli , Adeline Burguière , S. L. G. Cirillo , et al.
Molecular Microbiology, 2011, 80 (4), pp.919-934. ⟨10.1111/j.1365-2958.2011.07618.x⟩
Article dans une revue hal-00641589v1
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Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum Specimens

Pratt Kolia-Diafouka , Sylvain Godreuil , Arnaud Bourdin , Severine Carrer-Kremer , Laurent Kremer , et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.02224⟩
Article dans une revue hal-01887123v1
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Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

Estalina Báez-Ramírez , Luis Querales , Carlos Andres Aranaga , Gustavo López , Elba Guerrero , et al.
The Cell Surface, 2021, 7, pp.100060. ⟨10.1016/j.tcsw.2021.100060⟩
Article dans une revue inserm-03381892v2

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

Anil K Ojha , Anthony D Baughn , Dhinakaran Sambandan , Tsungda Hsu , Xavier Trivelli , et al.
Molecular Microbiology, 2008, 69 (1), pp.164-174. ⟨10.1111/j.1365-2958.2008.06274.x⟩
Article dans une revue hal-00292249v1
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Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains

Pierre Santucci , Nabil Smichi , Sadia Diomandé , Isabelle Poncin , Vanessa Point , et al.
FEBS Journal, 2019, ⟨10.1111/febs.14864⟩
Article dans une revue hal-02137694v1

Design, synthesis, anti‐mycobacterial and cytotoxic evaluation of C‐4 functionalized 1,8‐naphthalimide‐heterocyclic hydrazide conjugates

Shalini Shalini , Matt Johansen , Laurent Kremer , Vipan Kumar
Chemical Biology and Drug Design, 2019, 94 (1), pp.1300-1305. ⟨10.1111/cbdd.13503⟩
Article dans une revue inserm-02480347v1
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Mycobacterium abscessus

Yves-Marie Boudehen , Laurent Kremer
Trends in Microbiology, 2021, 29 (10), pp.951-952. ⟨10.1016/j.tim.2021.06.006⟩
Article dans une revue inserm-03381908v1
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Mycobacterium marinum MgtC Plays a Role in Phagocytosis but is Dispensable for Intracellular Multiplication

Claudine Belon , Laïla Gannoun-Zaki , Georges Lutfalla , Laurent Kremer , Anne-Béatrice Blanc-Potard
PLoS ONE, 2014, 9 (12), pp.e116052. ⟨10.1371/journal.pone.0116052⟩
Article dans une revue hal-02087386v1

The Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development.

Apoorva Bhatt , Virginie Molle , Gurdyal S Besra , William R Jacobs , Laurent Kremer
Molecular Microbiology, 2007, 64 (6), pp.1442-54. ⟨10.1111/j.1365-2958.2007.05761.x⟩
Article dans une revue hal-00167439v1
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Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus

Tanja Küssau , Niël van Wyk , Matt D Johansen , Husam M. A. B. Alsarraf , Aymeric Neyret , et al.
Cells, 2020, 9 (11), pp.2410. ⟨10.3390/cells9112410⟩
Article dans une revue inserm-02988325v1
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Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues

Geoffrey Coxon , Derek Craig , Rosa Milagros Corrales , Emilie Vialla , Laila Gannoun-Zaki , et al.
PLoS ONE, 2013, 8 (1), pp.e53162. ⟨10.1371/journal.pone.0053162⟩
Article dans une revue hal-02281784v1
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MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth

Vincent Delorme , Sadia V. Diomandé , Luc Dedieu , Jean-François Cavalier , Fredéric Carrière , et al.
PLoS ONE, 2012, 7 (9), pp.e46493. ⟨10.1371/journal.pone.0046493⟩
Article dans une revue hal-02646386v1

Base-Promoted Expedient Access to Spiroisatins: Synthesis and Antitubercular Evaluation of 1 H -1,2,3-Triazole-Tethered Spiroisatin–Ferrocene and Isatin–Ferrocene Conjugates

Kewal Kumar , Christophe Biot , Severine Carrere-Kremer , Laurent Kremer , Yann Guérardel , et al.
Organometallics, 2013, 32 (24), pp.7386-7398. ⟨10.1021/om4009229⟩
Article dans une revue hal-02263476v1
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Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: Role of the Mycobacterium smegmatis 1351 gene (MSMEG-1351) in cis-cyclopropanation of α-mycolates

Laeticia Alibaud , Anuradha Alahari , Xavier Trivelli , Anil K. Ojha , Graham F. Hatfull , et al.
Journal of Biological Chemistry, 2010, 285 (28), pp.21698-21707. ⟨10.1074/jbc.M110.125724⟩
Article dans une revue hal-00641584v1

MmpL8 MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family

Violaine Dubois , Albertus Viljoen , Laura Laencina , Vincent Le Moigne , Audrey Bernut , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (43), pp.E10147-E10156. ⟨10.1073/pnas.1812984115⟩
Article dans une revue hal-02137509v1

TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins.

Virginie Driss , Fanny Legrand , Emmanuel Hermann , Sylvie Loiseau , Yann Guerardel , et al.
Blood, 2009, 113 (14), pp.3235-44. ⟨10.1182/blood-2008-07-166595⟩
Article dans une revue hal-00373657v1

Overexpression of the Salmonella KdpF membrane peptide modulates expression of kdp genes and intramacrophage growth

Laila Gannoun-Zaki , Claudine Belon , Christian Dupont , Friederike Hilbert , Laurent Kremer , et al.
FEMS Microbiology Letters, 2014, 359 (1), pp.34-41. ⟨10.1111/1574-6968.12559⟩
Article dans une revue hal-02281803v1
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From the Characterization of the Four Serine/Threonine Protein Kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the Role of PknA and PknB in Cell Division.

Maria Fiuza , Marc J Canova , Isabelle Zanella-Cléon , Michel Becchi , Alain J Cozzone , et al.
Journal of Biological Chemistry, 2008, 283 (26), pp.18099-112. ⟨10.1074/jbc.M802615200⟩
Article dans une revue hal-00292250v1
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Mycobacterium abscessus, un modèle de résistance aux différentes classes d’antibiotiques

Morgane Illouz , Matthéo Alcaraz , Françoise Roquet-Banères , Laurent Kremer
Médecine/Sciences, 2021, 37 (11), pp.993-1001. ⟨10.1051/medsci/2021164⟩
Article dans une revue hal-03462547v1
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Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline

Jaryd R Sullivan , Andréanne Lupien , Elias Kalthoff , Claire Hamela , Lorne Taylor , et al.
PLoS Pathogens, 2021, 17 (10), pp.e1009965. ⟨10.1371/journal.ppat.1009965⟩
Article dans une revue inserm-03381888v1

X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).

Sudharsan Sridharan , Lei Wang , Alistair K Brown , Lynn G Dover , Laurent Kremer , et al.
Journal of Molecular Biology, 2007, 366 (2), pp.469-80. ⟨10.1016/j.jmb.2006.11.006⟩
Article dans une revue hal-00148924v1
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Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Jérôme Ruyck , Christian Dupont , Elodie Lamy , Vincent Le Moigne , Christophe Biot , et al.
ChemistryOpen, 2020, 9 (3), pp.351-365. ⟨10.1002/open.202000042⟩
Article dans une revue hal-02988322v1