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The Mycobacterium tuberculosis GroEL1 chaperone is a substrate of Ser/Thr protein kinases.
Marc J Canova
,
Laurent Kremer
,
Virginie Molle
Article dans une revue
hal-00373654v1
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The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria.
Anuradha Alahari
,
Nathalie Saint
,
Sylvie Campagna
,
Virginie Molle
,
Gérard Molle
,
et al.
Article dans une revue
hal-00167441v1
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Antimycobacterial activity and mechanism of action of NAS-91.
Paul Gratraud
,
Namita Surolia
,
Gurdyal Besra
,
Avadhesha Surolia
,
Laurent Kremer
Article dans une revue
hal-00202871v1
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Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus
Matthias Richard
,
Ana Victoria Gutiérrez
,
Albertus Viljoen
,
Eric Ghigo
,
Mickaël Blaise
,
et al.
Article dans une revue
hal-02137555v1
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Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus
Matthias Richard
,
Ana Victoria Gutiérrez
,
Albertus Viljoen
,
Daniela Rodriguez-Rincon
,
Françoise Roquet-Banères
,
et al.
Article dans une revue
hal-02137498v1
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The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold
Kien Lam Ung
,
Husam Alsarraf
,
Laurent Kremer
,
Mickael Blaise
Article dans une revue
hal-02988326v1
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CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model
Matt D Johansen
,
Laurent Kremer
Article dans une revue
inserm-02971833v1
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Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.
Anil K Ojha
,
Anthony D Baughn
,
Dhinakaran Sambandan
,
Tsungda Hsu
,
Xavier Trivelli
,
et al.
Article dans une revue
hal-00292249v1
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1 H -benzo[ d ]imidazole derivatives affect MmpL3 in Mycobacterium tuberculosis
Małgorzata Korycka-Machała
,
Albertus Viljoen
,
Jakub Pawełczyk
,
Paulina Borówka
,
Bożena Dziadek
,
et al.
Article dans une revue
hal-02202451v1
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A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos
Laeticia Alibaud
,
Yoann Rombouts
,
Xavier Trivelli
,
Adeline Burguière
,
S. L. G. Cirillo
,
et al.
Article dans une revue
hal-00641589v1
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Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2
Estalina Báez-Ramírez
,
Luis Querales
,
Carlos Andres Aranaga
,
Gustavo López
,
Elba Guerrero
,
et al.
Article dans une revue
inserm-03381892v2
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Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum Specimens
Pratt Kolia-Diafouka
,
Sylvain Godreuil
,
Arnaud Bourdin
,
Severine Carrer-Kremer
,
Laurent Kremer
,
et al.
Article dans une revue
hal-01887123v1
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Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains
Pierre Santucci
,
Nabil Smichi
,
Sadia Diomandé
,
Isabelle Poncin
,
Vanessa Point
,
et al.
Article dans une revue
hal-02137694v1
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Design, synthesis, anti‐mycobacterial and cytotoxic evaluation of C‐4 functionalized 1,8‐naphthalimide‐heterocyclic hydrazide conjugates
Shalini Shalini
,
Matt Johansen
,
Laurent Kremer
,
Vipan Kumar
Article dans une revue
inserm-02480347v1
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Mycobacterium abscessus
Yves-Marie Boudehen
,
Laurent Kremer
Article dans une revue
inserm-03381908v1
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Mycobacterium marinum MgtC Plays a Role in Phagocytosis but is Dispensable for Intracellular Multiplication
Claudine Belon
,
Laïla Gannoun-Zaki
,
Georges Lutfalla
,
Laurent Kremer
,
Anne-Béatrice Blanc-Potard
Article dans une revue
hal-02087386v1
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The Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development.
Apoorva Bhatt
,
Virginie Molle
,
Gurdyal S Besra
,
William R Jacobs
,
Laurent Kremer
Article dans une revue
hal-00167439v1
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Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus
Tanja Küssau
,
Niël van Wyk
,
Matt D Johansen
,
Husam M. A. B. Alsarraf
,
Aymeric Neyret
,
et al.
Article dans une revue
inserm-02988325v1
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Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues
Geoffrey Coxon
,
Derek Craig
,
Rosa Milagros Corrales
,
Emilie Vialla
,
Laila Gannoun-Zaki
,
et al.
Article dans une revue
hal-02281784v1
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MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth
Vincent Delorme
,
Sadia V. Diomandé
,
Luc Dedieu
,
Jean-François Cavalier
,
Fredéric Carrière
,
et al.
Article dans une revue
hal-02646386v1
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Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: Role of the Mycobacterium smegmatis 1351 gene (MSMEG-1351) in cis-cyclopropanation of α-mycolates
Laeticia Alibaud
,
Anuradha Alahari
,
Xavier Trivelli
,
Anil K. Ojha
,
Graham F. Hatfull
,
et al.
Article dans une revue
hal-00641584v1
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Base-Promoted Expedient Access to Spiroisatins: Synthesis and Antitubercular Evaluation of 1 H -1,2,3-Triazole-Tethered Spiroisatin–Ferrocene and Isatin–Ferrocene Conjugates
Kewal Kumar
,
Christophe Biot
,
Severine Carrere-Kremer
,
Laurent Kremer
,
Yann Guérardel
,
et al.
Article dans une revue
hal-02263476v1
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TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins.
Virginie Driss
,
Fanny Legrand
,
Emmanuel Hermann
,
Sylvie Loiseau
,
Yann Guerardel
,
et al.
Article dans une revue
hal-00373657v1
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MmpL8 MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family
Violaine Dubois
,
Albertus Viljoen
,
Laura Laencina
,
Vincent Le Moigne
,
Audrey Bernut
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (43), pp.E10147-E10156. ⟨10.1073/pnas.1812984115⟩
Article dans une revue
hal-02137509v1
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Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening
Léo Faion
,
Kamel Djaout
,
Rosangela Frita
,
Catalin Pintiala
,
Francois-Xavier Cantrelle
,
et al.
Article dans une revue
hal-02988077v1
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Overexpression of the Salmonella KdpF membrane peptide modulates expression of kdp genes and intramacrophage growth
Laila Gannoun-Zaki
,
Claudine Belon
,
Christian Dupont
,
Friederike Hilbert
,
Laurent Kremer
,
et al.
Article dans une revue
hal-02281803v1
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An improved method to unravel phosphoacceptors in Ser/Thr protein kinase-phosphorylated substrates
Virginie Molle
,
Jade Leiba
,
Isabelle Zanella-Cléon
,
Michel Becchi
,
Laurent Kremer
Article dans une revue
istex
hal-02282736v1
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From the Characterization of the Four Serine/Threonine Protein Kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the Role of PknA and PknB in Cell Division.
Maria Fiuza
,
Marc J Canova
,
Isabelle Zanella-Cléon
,
Michel Becchi
,
Alain J Cozzone
,
et al.
Article dans une revue
hal-00292250v1
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X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).
Sudharsan Sridharan
,
Lei Wang
,
Alistair K Brown
,
Lynn G Dover
,
Laurent Kremer
,
et al.
Article dans une revue
hal-00148924v1
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Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors
Jérôme Ruyck
,
Christian Dupont
,
Elodie Lamy
,
Vincent Le Moigne
,
Christophe Biot
,
et al.
Article dans une revue
hal-02988322v1
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